arXiv subjects

Jian Wu

Publications and source records attributed to Jian Wu.

At least 145 records · Page 8Linked to original sources

arXiv2025

AI Scientists Fail Without Strong Implementation Capability

The emergence of Artificial Intelligence (AI) Scientist represents a paradigm shift in scientific discovery, with large language models (LLMs) taking the lead as the primary executor in the entire scientific workflow from idea generation to experiment implementation. Recent AI Scientist studies demonstrate sufficient capabilities for independent scientific discovery, with the generated research reports gaining acceptance at the ICLR 2025 workshop and ACL 2025, arguing that a human-level AI Scientist, capable of uncovering phenomena previously unknown to humans, may be imminent. Despite this substantial progress, AI Scientist has yet to produce a groundbreaking achievement in the domain of computer science on par with automated scientific tools. Based on extensive quantitative evidence from existing benchmarks in complex engineering tasks and a systematic evaluation assess 28 research papers generated by five advanced AI Scientist systems, we argue that \textbf{the fundamental bottleneck for AI Scientists lies in their capability to execute the requisite verification procedures.} Current AI Scientist systems lack the execution capabilities needed to execute rigorous experiments and produce high-quality scientific papers. To better illustrate the root cause of this \textbf{implementation gap}, we provide an in-depth discussion on the fundamental limitations of AI Scientist. This position paper aims to call for the participants in the community to bridge the implementation gap.

cs.AI↗

arXiv2025

Group-On: Boosting One-Shot Segmentation with Supportive Query

One-shot semantic segmentation aims to segment query images given only ONE annotated support image of the same class. This task is challenging because target objects in the support and query images can be largely different in appearance and pose (i.e., intra-class variation). Prior works suggested that incorporating more annotated support images in few-shot settings boosts performances but increases costs due to additional manual labeling. In this paper, we propose a novel and effective approach for ONE-shot semantic segmentation, called Group-On, which packs multiple query images in batches for the benefit of mutual knowledge support within the same category. Specifically, after coarse segmentation masks of the batch of queries are predicted, query-mask pairs act as pseudo support data to enhance mask predictions mutually. To effectively steer such process, we construct an innovative MoME module, where a flexible number of mask experts are guided by a scene-driven router and work together to make comprehensive decisions, fully promoting mutual benefits of queries. Comprehensive experiments on three standard benchmarks show that, in the ONE-shot setting, Group-On significantly outperforms previous works by considerable margins. With only one annotated support image, Group-On can be even competitive with the counterparts using 5 annotated images.

cs.CV↗

arXiv2025

LLMs Can Simulate Standardized Patients via Agent Coevolution

Training medical personnel using standardized patients (SPs) remains a complex challenge, requiring extensive domain expertise and role-specific practice. Previous research on Large Language Model (LLM)-based SPs mostly focuses on improving data retrieval accuracy or adjusting prompts through human feedback. However, this focus has overlooked the critical need for patient agents to learn a standardized presentation pattern that transforms data into human-like patient responses through unsupervised simulations. To address this gap, we propose EvoPatient, a novel simulated patient framework in which a patient agent and doctor agents simulate the diagnostic process through multi-turn dialogues, simultaneously gathering experience to improve the quality of both questions and answers, ultimately enabling human doctor training. Extensive experiments on various cases demonstrate that, by providing only overall SP requirements, our framework improves over existing reasoning methods by more than 10\% in requirement alignment and better human preference, while achieving an optimal balance of resource consumption after evolving over 200 cases for 10 hours, with excellent generalizability. Our system will be available at https://github.com/ZJUMAI/EvoPatient.

cs.CL↗

arXiv2025

Modality-Fair Preference Optimization for Trustworthy MLLM Alignment

Multimodal large language models (MLLMs) have achieved remarkable success across various tasks. However, separate training of visual and textual encoders often results in a misalignment of the modality. Such misalignment may lead models to generate content that is absent from the input image, a phenomenon referred to as hallucination. These inaccuracies severely undermine the trustworthiness of MLLMs in real-world applications. Despite attempts to optimize text preferences to mitigate this issue, our initial investigation indicates that the trustworthiness of MLLMs remains inadequate. Specifically, these models tend to provide preferred answers even when the input image is heavily distorted. Analysis of visual token attention also indicates that the model focuses primarily on the surrounding context rather than the key object referenced in the question. These findings highlight a misalignment between the modalities, where answers inadequately leverage input images. Motivated by our findings, we propose Modality-Fair Preference Optimization (MFPO), which comprises three components: the construction of a multimodal preference dataset in which dispreferred images differ from originals solely in key regions; an image reward loss function encouraging the model to generate answers better aligned with the input images; and an easy-to-hard iterative alignment strategy to stabilize joint modality training. Extensive experiments on three trustworthiness benchmarks demonstrate that MFPO significantly enhances the trustworthiness of MLLMs. In particular, it enables the 7B models to attain trustworthiness levels on par with, or even surpass, those of the 13B, 34B, and larger models.

cs.CV↗

arXiv2025

Reason from Future: Reverse Thought Chain Enhances LLM Reasoning

It has been demonstrated that carefully designed reasoning paradigms, like Chain-of-Thought (CoT) and Tree-of-Thought (ToT), can enhance the reasoning capabilities of small language models by detailed thinking and extensive thought searching, unbounded branching factors in the searching space create prohibitive reasoning consumption. However these methods fall into the trap of local optimum reasoning, which means the model lacks a global perspective while solving problems. We propose a novel reasoning paradigm called Reason from Future (RFF), which generates reasoning paths by bidirectional reasoning that combines top-down planning with bottom-up reasoning accumulation. The essence of RFF lies in its reverse reasoning mechanism, which prioritizes core logical relationships and imposes goal-oriented constraints on intermediate steps, thereby reducing the searching space and mitigating error accumulation inherent in sequential forward reasoning. Empirical evaluations across diverse experiments demonstrate that RFF outperforms conventional paradigms with higher accuracy and less searching space to solve complex tasks.

cs.AI↗

arXiv2025

STORM: Benchmarking Visual Rating of MLLMs with a Comprehensive Ordinal Regression Dataset

Visual rating is an essential capability of artificial intelligence (AI) for multi-dimensional quantification of visual content, primarily applied in ordinal regression (OR) tasks such as image quality assessment, facial age estimation, and medical image grading. However, current multi-modal large language models (MLLMs) under-perform in such visual rating ability while also suffering the lack of relevant datasets and benchmarks. In this work, we collect and present STORM, a data collection and benchmark for Stimulating Trustworthy Ordinal Regression Ability of MLLMs for universal visual rating. STORM encompasses 14 ordinal regression datasets across five common visual rating domains, comprising 655K image-level pairs and the corresponding carefully curated VQAs. Importantly, we also propose a coarse-to-fine processing pipeline that dynamically considers label candidates and provides interpretable thoughts, providing MLLMs with a general and trustworthy ordinal thinking paradigm. This benchmark aims to evaluate the all-in-one and zero-shot performance of MLLMs in scenarios requiring understanding of the essential common ordinal relationships of rating labels. Extensive experiments demonstrate the effectiveness of our framework and shed light on better fine-tuning strategies. The STORM dataset, benchmark, and pre-trained models are available on the following webpage to support further research in this area. Datasets and codes are released on the project page: https://storm-bench.github.io/.

cs.CV↗

arXiv2025

HSCR: Hierarchical Self-Contrastive Rewarding for Aligning Medical Vision Language Models

Medical Vision-Language Models (Med-VLMs) have achieved success across various tasks, yet most existing methods overlook the modality misalignment issue that can lead to untrustworthy responses in clinical settings. In this paper, we propose Hierarchical Self-Contrastive Rewarding (HSCR), a novel approach that addresses two critical challenges in Med-VLM alignment: 1) Cost-effective generation of high-quality preference data; 2) Capturing nuanced and context-aware preferences for improved alignment. HSCR first leverages the inherent capability of Med-VLMs to generate dispreferred responses with higher sampling probability. By analyzing output logit shifts after visual token dropout, we identify modality-coupled tokens that induce misalignment and derive an implicit alignment reward function. This function guides token replacement with hallucinated ones during decoding, producing high-quality dispreferred data. Furthermore, HSCR introduces a multi-level preference optimization strategy, which extends beyond traditional adjacent-level optimization by incorporating nuanced implicit preferences, leveraging relative quality in dispreferred data to capture subtle alignment cues for more precise and context-aware optimization. Extensive experiments across multiple medical tasks, including Med-VQA, medical image captioning and instruction following, demonstrate that HSCR not only enhances zero-shot performance but also significantly improves modality alignment and trustworthiness with just 2,000 training entries.

cs.CV↗

arXiv2025

MagiCodec: Simple Masked Gaussian-Injected Codec for High-Fidelity Reconstruction and Generation

Neural audio codecs have made significant strides in efficiently mapping raw audio waveforms into discrete token representations, which are foundational for contemporary audio generative models. However, most existing codecs are optimized primarily for reconstruction quality, often at the expense of the downstream modelability of the encoded tokens. Motivated by the need to overcome this bottleneck, we introduce $\textbf{MagiCodec}$, a novel single-layer, streaming Transformer-based audio codec. MagiCodec is designed with a multistage training pipeline that incorporates Gaussian noise injection and latent regularization, explicitly targeting the enhancement of semantic expressiveness in the generated codes while preserving high reconstruction fidelity. We analytically derive the effect of noise injection in the frequency domain, demonstrating its efficacy in attenuating high-frequency components and fostering robust tokenization. Extensive experimental evaluations show that MagiCodec surpasses state-of-the-art codecs in both reconstruction quality and downstream tasks. Notably, the tokens produced by MagiCodec exhibit Zipf-like distributions, as observed in natural languages, thereby improving compatibility with language-model-based generative architectures. The code and pre-trained models are available at https://github.com/Ereboas/MagiCodec.

cs.SD↗

arXiv2025

Rethinking Neural-based Matrix Inversion: Why can't, and Where can

Deep neural networks have achieved substantial success across various scientific computing tasks. A pivotal challenge within this domain is the rapid and parallel approximation of matrix inverses, critical for numerous applications. Despite significant progress, there currently exists no universal neural-based method for approximating matrix inversion. This paper presents a theoretical analysis demonstrating the fundamental limitations of neural networks in developing a general matrix inversion model. We expand the class of Lipschitz functions to encompass a wider array of neural network models, thereby refining our theoretical approach. Moreover, we delineate specific conditions under which neural networks can effectively approximate matrix inverses. Our theoretical results are supported by experimental results from diverse matrix datasets, exploring the efficacy of neural networks in addressing the matrix inversion challenge.

cs.LG↗

arXiv2025

From Misleading Queries to Accurate Answers: A Three-Stage Fine-Tuning Method for LLMs

Large language models (LLMs) exhibit excellent performance in natural language processing (NLP), but remain highly sensitive to the quality of input queries, especially when these queries contain misleading or inaccurate information. Existing methods focus on correcting the output, but they often overlook the potential of improving the ability of LLMs to detect and correct misleading content in the input itself. In this paper, we propose a novel three-stage fine-tuning method that enhances the ability of LLMs to detect and correct misleading information in the input, further improving response accuracy and reducing hallucinations. Specifically, the three stages include (1) training LLMs to identify misleading information, (2) training LLMs to correct the misleading information using built-in or external knowledge, and (3) training LLMs to generate accurate answers based on the corrected queries. To evaluate our method, we conducted experiments on three datasets for the hallucination detection task and the question answering~(QA) task, as well as two datasets containing misleading information that we constructed. The experimental results demonstrate that our method significantly improves the accuracy and factuality of LLM responses, while also enhancing the ability to detect hallucinations and reducing the generation of hallucinations in the output, particularly when the query contains misleading information.

cs.CL↗

arXiv2025

MT$^{3}$: Scaling MLLM-based Text Image Machine Translation via Multi-Task Reinforcement Learning

Text Image Machine Translation (TIMT)-the task of translating textual content embedded in images-is critical for applications in accessibility, cross-lingual information access, and real-world document understanding. However, TIMT remains a complex challenge due to the need for accurate optical character recognition (OCR), robust visual-text reasoning, and high-quality translation, often requiring cascading multi-stage pipelines. Recent advances in large-scale Reinforcement Learning (RL) have improved reasoning in Large Language Models (LLMs) and Multimodal LLMs (MLLMs), but their application to end-to-end TIMT is still underexplored. To bridge this gap, we introduce MT$^{3}$, the first framework to apply Multi-Task RL to MLLMs for end-to-end TIMT. MT$^{3}$ adopts a multi-task optimization paradigm targeting three key sub-skills: text recognition, context-aware reasoning, and translation. It is trained using a novel multi-mixed reward mechanism that adapts rule-based RL strategies to TIMT's intricacies, offering fine-grained, non-binary feedback across tasks. Furthermore, to facilitate the evaluation of TIMT in authentic cross-cultural and real-world social media contexts, we introduced XHSPost, the first social media TIMT benchmark. Our MT$^{3}$-7B-Zero achieves state-of-the-art results on the latest in-domain MIT-10M benchmark, outperforming strong baselines such as Qwen2.5-VL-72B and InternVL2.5-78B by notable margins across multiple metrics. Additionally, the model shows strong generalization to out-of-distribution language pairs and datasets. In-depth analyses reveal how multi-task synergy, reinforcement learning initialization, curriculum design, and reward formulation contribute to advancing MLLM-driven TIMT.

cs.CL↗

arXiv2025

Towards Reliable Large Audio Language Model

Recent advancements in large audio language models (LALMs) have demonstrated impressive results and promising prospects in universal understanding and reasoning across speech, music, and general sound. However, these models still lack the ability to recognize their knowledge boundaries and refuse to answer questions they don't know proactively. While there have been successful attempts to enhance the reliability of LLMs, reliable LALMs remain largely unexplored. In this paper, we systematically investigate various approaches towards reliable LALMs, including training-free methods such as multi-modal chain-of-thought (MCoT), and training-based methods such as supervised fine-tuning (SFT). Besides, we identify the limitations of previous evaluation metrics and propose a new metric, the Reliability Gain Index (RGI), to assess the effectiveness of different reliable methods. Our findings suggest that both training-free and training-based methods enhance the reliability of LALMs to different extents. Moreover, we find that awareness of reliability is a "meta ability", which can be transferred across different audio modalities, although significant structural and content differences exist among sound, music, and speech.

cs.SD↗

arXiv2025

A Framework for Spontaneous Brillouin Noise: Unveiling Fundamental Limits in Brillouin Metrology

Spontaneous Brillouin scattering (SpBS) provides a non-contact tool for probing the mechanical and thermodynamic properties of materials, enabling important applications such as distributed optical fiber sensing and high-resolution Brillouin microscopy. Achieving metrological precision in these systems relies critically on identifying fundamental noise sources. While a pioneering study three decades ago numerically investigated an intrinsic SpBS noise mechanism, this phenomenon has remained largely unexplored, particularly in the context of Brillouin metrological systems. Here, by revisiting its physical formation process and rethinking its stochastic behaviors, we develop and experimentally validate a comprehensive analytical framework on this long-overlooked noise source. Importantly, we theoretically predict, for the first time, the SpBS noise is a universal and fundamental limit that can dominate over conventional limits such as shot noise in Brillouin metrological systems like imaging, microscopy and sensing. Specifically, we experimentally demonstrate the SpBS-noise-limited regime in Brillouin imaging and sensing scenarios. This framework establishes a critical foundation for understanding and optimizing the performance bounds of current and future Brillouin-based technologies across diverse applications.

physics.optics↗

arXiv2025

Dual-level Fuzzy Learning with Patch Guidance for Image Ordinal Regression

Ordinal regression bridges regression and classification by assigning objects to ordered classes. While human experts rely on discriminative patch-level features for decisions, current approaches are limited by the availability of only image-level ordinal labels, overlooking fine-grained patch-level characteristics. In this paper, we propose a Dual-level Fuzzy Learning with Patch Guidance framework, named DFPG that learns precise feature-based grading boundaries from ambiguous ordinal labels, with patch-level supervision. Specifically, we propose patch-labeling and filtering strategies to enable the model to focus on patch-level features exclusively with only image-level ordinal labels available. We further design a dual-level fuzzy learning module, which leverages fuzzy logic to quantitatively capture and handle label ambiguity from both patch-wise and channel-wise perspectives. Extensive experiments on various image ordinal regression datasets demonstrate the superiority of our proposed method, further confirming its ability in distinguishing samples from difficult-to-classify categories. The code is available at https://github.com/ZJUMAI/DFPG-ord.

cs.CV↗

arXiv2025

Uncertainty-Aware Multi-Expert Knowledge Distillation for Imbalanced Disease Grading

Automatic disease image grading is a significant application of artificial intelligence for healthcare, enabling faster and more accurate patient assessments. However, domain shifts, which are exacerbated by data imbalance, introduce bias into the model, posing deployment difficulties in clinical applications. To address the problem, we propose a novel \textbf{U}ncertainty-aware \textbf{M}ulti-experts \textbf{K}nowledge \textbf{D}istillation (UMKD) framework to transfer knowledge from multiple expert models to a single student model. Specifically, to extract discriminative features, UMKD decouples task-agnostic and task-specific features with shallow and compact feature alignment in the feature space. At the output space, an uncertainty-aware decoupled distillation (UDD) mechanism dynamically adjusts knowledge transfer weights based on expert model uncertainties, ensuring robust and reliable distillation. Additionally, UMKD also tackles the problems of model architecture heterogeneity and distribution discrepancies between source and target domains, which are inadequately tackled by previous KD approaches. Extensive experiments on histology prostate grading (\textit{SICAPv2}) and fundus image grading (\textit{APTOS}) demonstrate that UMKD achieves a new state-of-the-art in both source-imbalanced and target-imbalanced scenarios, offering a robust and practical solution for real-world disease image grading.

cs.CV↗

arXiv2025

Matrix Factorization with Dynamic Multi-view Clustering for Recommender System

Matrix factorization (MF), a cornerstone of recommender systems, decomposes user-item interaction matrices into latent representations. Traditional MF approaches, however, employ a two-stage, non-end-to-end paradigm, sequentially performing recommendation and clustering, resulting in prohibitive computational costs for large-scale applications like e-commerce and IoT, where billions of users interact with trillions of items. To address this, we propose Matrix Factorization with Dynamic Multi-view Clustering (MFDMC), a unified framework that balances efficient end-to-end training with comprehensive utilization of web-scale data and enhances interpretability. MFDMC leverages dynamic multi-view clustering to learn user and item representations, adaptively pruning poorly formed clusters. Each entity's representation is modeled as a weighted projection of robust clusters, capturing its diverse roles across views. This design maximizes representation space utilization, improves interpretability, and ensures resilience for downstream tasks. Extensive experiments demonstrate MFDMC's superior performance in recommender systems and other representation learning domains, such as computer vision, highlighting its scalability and versatility.

cs.IR↗

arXiv2025

OmniV-Med: Scaling Medical Vision-Language Model for Universal Visual Understanding

The practical deployment of medical vision-language models (Med-VLMs) necessitates seamless integration of textual data with diverse visual modalities, including 2D/3D images and videos, yet existing models typically employ separate encoders for different modalities. To address this limitation, we present OmniV-Med, a unified framework for multimodal medical understanding. Our technical contributions are threefold: First, we construct OmniV-Med-Instruct, a comprehensive multimodal medical dataset containing 252K instructional samples spanning 14 medical image modalities and 11 clinical tasks. Second, we devise a rotary position-adaptive encoder that processes multi-resolution 2D/3D images and videos within a unified architecture, diverging from conventional modality-specific encoders. Third, we introduce a medical-aware token pruning mechanism that exploits spatial-temporal redundancy in volumetric data (e.g., consecutive CT slices) and medical videos, effectively reducing 60\% of visual tokens without performance degradation. Empirical evaluations demonstrate that OmniV-Med-7B achieves state-of-the-art performance on 7 benchmarks spanning 2D/3D medical imaging and video understanding tasks. Notably, our lightweight variant (OmniV-Med-1.5B) attains comparable performance while requiring only 8 RTX3090 GPUs for training and supporting efficient long-video inference. Data, code and model will be released.

cs.CL↗

arXiv2025

ProtFlow: Fast Protein Sequence Design via Flow Matching on Compressed Protein Language Model Embeddings

The design of protein sequences with desired functionalities is a fundamental task in protein engineering. Deep generative methods, such as autoregressive models and diffusion models, have greatly accelerated the discovery of novel protein sequences. However, these methods mainly focus on local or shallow residual semantics and suffer from low inference efficiency, large modeling space and high training cost. To address these challenges, we introduce ProtFlow, a fast flow matching-based protein sequence design framework that operates on embeddings derived from semantically meaningful latent space of protein language models. By compressing and smoothing the latent space, ProtFlow enhances performance while training on limited computational resources. Leveraging reflow techniques, ProtFlow enables high-quality single-step sequence generation. Additionally, we develop a joint design pipeline for the design scene of multichain proteins. We evaluate ProtFlow across diverse protein design tasks, including general peptides and long-chain proteins, antimicrobial peptides, and antibodies. Experimental results demonstrate that ProtFlow outperforms task-specific methods in these applications, underscoring its potential and broad applicability in computational protein sequence design and analysis.

cs.LG↗