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Jianbin Wang

Publications and source records attributed to Jianbin Wang.

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Reconstructing the Invisible Fraction of Semi-visible Jets in ISR-Boosted Events via Neural Network Regression

Semi-visible jets (SVJs) provide a characteristic collider signature of strongly interacting dark sectors, in which the key model parameter $r_{\mathrm{inv}}$ controls the fraction of dark hadrons decaying to dark matter candidates. In this work, a regression model is developed to reconstruct $r_{\mathrm{inv}}$ in SVJ events produced in association with an energetic photon. The model uses information from high-level physics objects only, and the training procedure is optimized to ensure applicability. The performance is found to be robust against varying signal parameters and $r_{\mathrm{inv}}$ can be reconstructed at a much higher precision, compared to previously developed analytical method. It offers a new approach to conduct SVJ searches that can potentially unify both $s$-channel and $t$-channel productions, enhancing the sensitivities.

hep-ph

Cell lineage tracing using nuclease barcoding

Lineage tracing, the determination and mapping of progeny arising from single cells, is an important approach enabling the elucidation of mechanisms underlying diverse biological processes ranging from development to disease. We developed a dynamic sequence-based barcode for lineage tracing and have demonstrated its performance in C. elegans, a model organism whose lineage tree is well established. The strategy we use creates lineage trees based upon the introduction of specific mutations into cells and the propagation of these mutations to daughter cells at each cell division. We present an experimental proof of concept along with a corresponding simulation and analytical model for deeper understanding of the coding capacity of the system. By introducing mutations in a predictable manner using CRISPR/Cas9, our technology will enable more complete investigations of cellular processes.

q-bio.GN