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Jianbing Zhu

Publications and source records attributed to Jianbing Zhu.

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Promise and challenges of heart chamber segmentation from non-contrast CT scans using contrastive unpaired image translation: a feasibility study

Purpose: To evaluate the feasibility and challenges of heart chamber segmentation from non-contrast CT scans using contrastive unpaired image translation and deep learning-based segmentation. Approach: We developed ChameleonNet, a framework utilizing the Contrastive Unpaired Translation (CUT) network with decoupled contrastive learning (DCL) loss to synthesize non-contrast CT from contrast CT scans. Using annotations of four heart chambers (left atrium (LA), left ventricle (LV), right atrium (RA), and right ventricle (RV)) from contrast scans, we trained a Hausdorff distance loss-enhanced nnU-Net on synthesized non-contrast images. The translation model was trained with 35,538 contrast-enhanced and 37,197 non-contrast CT slices. The segmentation model was trained with 292 synthesized non-contrast scans. Performance was evaluated using Dice similarity coefficient (DSC) and 95th Hausdorff distance (HD95) on 36 synthesized non-contrast scans, and volume agreement on 36 real non-contrast CT scans was assessed using Pearson correlation, mean absolute percentage error (MAPE), and mean percentage error (MPE). Results: The segmentation model achieved DSC of 0.94 (0.01), 0.91 (0.04), 0.92 (0.03), 0.93 (0.02), and HD95 of 3.63 (1.49), 5.74 (4.08), 5.18 (1.77), 5.51 (3.21) mm on synthesized non-contrast images for LA, LV, RA, and RV, respectively. On real non-contrast CT scans, Pearson correlations were 0.93, 0.82, 0.87, and 0.89 (all p<0.001), with MAPE ranging from 9.22% to 20.79%, and MPE ranging from -12.52% to 4.67%. Conclusions: ChameleonNet demonstrated feasibility for heart chamber segmentation from non-contrast CT without manual non-contrast annotations. However, volume errors, particularly for LV and RV, indicate that further refinement and validation are needed before clinical use.

eess.IV

MD Loss: Efficient Training of 3D Seismic Fault Segmentation Network under Sparse Labels by Weakening Anomaly Annotation

Data-driven fault detection has been regarded as a 3D image segmentation task. The models trained from synthetic data are difficult to generalize in some surveys. Recently, training 3D fault segmentation using sparse manual 2D slices is thought to yield promising results, but manual labeling has many false negative labels (abnormal annotations), which is detrimental to training and consequently to detection performance. Motivated to train 3D fault segmentation networks under sparse 2D labels while suppressing false negative labels, we analyze the training process gradient and propose the Mask Dice (MD) loss. Moreover, the fault is an edge feature, and current encoder-decoder architectures widely used for fault detection (e.g., U-shape network) are not conducive to edge representation. Consequently, Fault-Net is proposed, which is designed for the characteristics of faults, employs high-resolution propagation features, and embeds MultiScale Compression Fusion block to fuse multi-scale information, which allows the edge information to be fully preserved during propagation and fusion, thus enabling advanced performance via few computational resources. Experimental demonstrates that MD loss supports the inclusion of human experience in training and suppresses false negative labels therein, enabling baseline models to improve performance and generalize to more surveys. Fault-Net is capable to provide a more stable and reliable interpretation of faults, it uses extremely low computational resources and inference is significantly faster than other models. Our method indicates optimal performance in comparison with several mainstream methods.

cs.CV

Attention-Based 3D Seismic Fault Segmentation Training by a Few 2D Slice Labels

Detection faults in seismic data is a crucial step for seismic structural interpretation, reservoir characterization and well placement. Some recent works regard it as an image segmentation task. The task of image segmentation requires huge labels, especially 3D seismic data, which has a complex structure and lots of noise. Therefore, its annotation requires expert experience and a huge workload. In this study, we present lambda-BCE and lambda-smooth L1loss to effectively train 3D-CNN by some slices from 3D seismic data, so that the model can learn the segmentation of 3D seismic data from a few 2D slices. In order to fully extract information from limited data and suppress seismic noise, we propose an attention module that can be used for active supervision training and embedded in the network. The attention heatmap label is generated by the original label, and letting it supervise the attention module using the lambda-smooth L1loss. The experiment demonstrates the effectiveness of our loss function, the method can extract 3D seismic features from a few 2D slice labels. And it also shows the advanced performance of the attention module, which can significantly suppress the noise in the seismic data while increasing the model's sensitivity to the foreground. Finally, on the public test set, we only use the 2D slice labels training that accounts for 3.3% of the 3D volume label, and achieve similar performance to the 3D volume label training.

cs.CV

Crossover-Net: Leveraging the Vertical-Horizontal Crossover Relation for Robust Segmentation

Robust segmentation for non-elongated tissues in medical images is hard to realize due to the large variation of the shape, size, and appearance of these tissues in different patients. In this paper, we present an end-to-end trainable deep segmentation model termed Crossover-Net for robust segmentation in medical images. Our proposed model is inspired by an insightful observation: during segmentation, the representation from the horizontal and vertical directions can provide different local appearance and orthogonality context information, which helps enhance the discrimination between different tissues by simultaneously learning from these two directions. Specifically, by converting the segmentation task to a pixel/voxel-wise prediction problem, firstly, we originally propose a cross-shaped patch, namely crossover-patch, which consists of a pair of (orthogonal and overlapped) vertical and horizontal patches, to capture the orthogonal vertical and horizontal relation. Then, we develop the Crossover-Net to learn the vertical-horizontal crossover relation captured by our crossover-patches. To achieve this goal, for learning the representation on a typical crossover-patch, we design a novel loss function to (1) impose the consistency on the overlap region of the vertical and horizontal patches and (2) preserve the diversity on their non-overlap regions. We have extensively evaluated our method on CT kidney tumor, MR cardiac, and X-ray breast mass segmentation tasks. Promising results are achieved according to our extensive evaluation and comparison with the state-of-the-art segmentation models.

eess.IV

Crossbar-Net: A Novel Convolutional Network for Kidney Tumor Segmentation in CT Images

Due to the irregular motion, similar appearance and diverse shape, accurate segmentation of kidney tumor in CT images is a difficult and challenging task. To this end, we present a novel automatic segmentation method, termed as Crossbar-Net, with the goal of accurate segmenting the kidney tumors. Firstly, considering that the traditional learning-based segmentation methods normally employ either whole images or squared patches as the training samples, we innovatively sample the orthogonal non-squared patches (namely crossbar patches), to fully cover the whole kidney tumors in either horizontal or vertical directions. These sampled crossbar patches could not only represent the detailed local information of kidney tumor as the traditional patches, but also describe the global appearance from either horizontal or vertical direction using contextual information. Secondly, with the obtained crossbar patches, we trained a convolutional neural network with two sub-models (i.e., horizontal sub-model and vertical sub-model) in a cascaded manner, to integrate the segmentation results from two directions (i.e., horizontal and vertical). This cascaded training strategy could effectively guarantee the consistency between sub-models, by feeding each other with the most difficult samples, for a better segmentation. In the experiment, we evaluate our method on a real CT kidney tumor dataset, collected from 94 different patients including 3,500 images. Compared with the state-of-the-art segmentation methods, the results demonstrate the superior results of our method on dice ratio score, true positive fraction, centroid distance and Hausdorff distance. Moreover, we have extended our crossbar-net to a different task: cardiac segmentation, showing the promising results for the better generalization.

cs.CV