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Jianchuan Yang

Publications and source records attributed to Jianchuan Yang.

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Physics-Informed Hemodynamic Modeling for Data-Free Prediction and Sparse-Data Assimilation

Clinical decision-making for coronary intervention relies mainly on angiography and fractional flow reserve (FFR). However, angiography is two-dimensional and lacks depth information for 3D lesion characterization, while FFR provides only a single functional index, offering limited hemodynamic insight. Among existing methods, numerical analysis is computationally expensive, whereas learning-based approaches require extensive supervision and often lack physical consistency. To address these limitations, we propose physics-informed hemodynamic modeling, an integrated deep learning framework for 3D coronary blood flow analysis from dual-view angiography. First, an attention-enhanced CNN reconstructs coronary geometry from angiography. The resulting point clouds are then mapped to a reference domain and Fourier-encoded for joint representation. A decoupled network separately predicts velocity and pressure fields, with embedded physical priors enabling efficient transfer across physiological conditions. Across 32 clinical patients evaluated under four flow conditions, the trans-stenotic pressure-drop mean absolute percentage error was 2.02%, while the velocity and pressure relative-L2 errors were 0.054 and 0.023, respectively. Validation against hospital-measured FFR further achieved 93.8% diagnostic accuracy (30/32; exact 95% CI, 79.2%-99.2%). The framework also supports illustrative revascularization comparisons and sparse-data assimilation, with the full angiography-to-hemodynamics pipeline completed within 20 minutes per patient.

eess.IV

Solved in Unit Domain: JacobiNet for Differentiable Coordinate-Transformed PINNs

Physics-Informed Neural Networks (PINNs) offer a powerful framework for solving PDEs by embedding physical laws into the learning process. However, when applied to domains with irregular boundaries, PINNs often suffer from instability and slow convergence, which stems from (1) inconsistent normalization due to geometric anisotropy, (2) inaccurate boundary enforcement, and (3) imbalanced loss term competition. A common workaround is to map the domain to a regular space. Yet, conventional mapping methods rely on case-specific meshes, define Jacobians at pre-specified fixed nodes, reformulate PDEs via the chain rule-making them incompatible with modern automatic differentiation, tensor-based frameworks. To bridge this gap, we propose JacobiNet, a learning-based coordinate-transformed PINN framework that unifies domain mapping and PDE solving within an end-to-end differentiable architecture. JacobiNet enables direct Jacobian computation via autograd, shares computation graph with downstream PINNs, thereby avoiding case-specific meshing, explicit Jacobian computation/storage, and manual PDE reformulation while unlocking geometric-editing operations. Separating physical modeling from geometric complexity, JacobiNet (1) addresses normalization challenges in the original anisotropic coordinates, (2) facilitates the hard enforcement of boundary conditions, and (3) mitigates the long-standing imbalance among loss terms. Evaluated on various PDEs, JacobiNet reduces the relative L2 error from 0.11-0.73 to 0.01-0.09, achieving an average 15.6x improvement in accuracy. In vessel-like domains with varying shapes, JacobiNet enables millisecond-level mapping inference for unseen geometries, improves prediction accuracy by an average of 3.65x, while delivering over 10x speedup-demonstrating strong generalization, accuracy, and efficiency.

cs.LG

FEM-Informed Hypergraph Neural Networks for Efficient Elastoplasticity

Graph neural networks (GNNs) naturally align with sparse operators and unstructured discretizations, making them a promising paradigm for physics-informed machine learning in computational mechanics. Motivated by discrete physics losses and Hierarchical Deep Learning Neural Network (HiDeNN) constructions, we embed finite-element (FEM) computations at nodes and Gauss points directly into message-passing layers and propose a numerically consistent FEM-Informed Hypergraph Neural Networks (FHGNN). Similar to conventional physics-informed neural networks (PINNs), training is purely physics-driven and requires no labeled data: the input is a node element hypergraph whose edges encode mesh connectivity. Guided by empirical results and condition-number analysis, we adopt an efficient variational loss. Validated on 3D benchmarks, including cyclic loading with isotropic/kinematic hardening, the proposed method delivers substantially improved accuracy and efficiency over recent, competitive PINN variants. By leveraging GPU-parallel tensor operations and the discrete representation, it scales effectively to large elastoplastic problems and can be competitive with, or faster than, multi-core FEM implementations at comparable accuracy. This work establishes a foundation for scalable, physics-embedded learning in nonlinear solid mechanics.

cs.LG