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Jiangpeng Yan

Publications and source records attributed to Jiangpeng Yan.

28 records · Page 2Linked to original sources

Towards better understanding and better generalization of few-shot classification in histology images with contrastive learning

Few-shot learning is an established topic in natural images for years, but few work is attended to histology images, which is of high clinical value since well-labeled datasets and rare abnormal samples are expensive to collect. Here, we facilitate the study of few-shot learning in histology images by setting up three cross-domain tasks that simulate real clinics problems. To enable label-efficient learning and better generalizability, we propose to incorporate contrastive learning (CL) with latent augmentation (LA) to build a few-shot system. CL learns useful representations without manual labels, while LA transfers semantic variations of the base dataset in an unsupervised way. These two components fully exploit unlabeled training data and can scale gracefully to other label-hungry problems. In experiments, we find i) models learned by CL generalize better than supervised learning for histology images in unseen classes, and ii) LA brings consistent gains over baselines. Prior studies of self-supervised learning mainly focus on ImageNet-like images, which only present a dominant object in their centers. Recent attention has been paid to images with multi-objects and multi-textures. Histology images are a natural choice for such a study. We show the superiority of CL over supervised learning in terms of generalization for such data and provide our empirical understanding for this observation. The findings in this work could contribute to understanding how the model generalizes in the context of both representation learning and histological image analysis. Code is available.

eess.IV↗

Value Activation for Bias Alleviation: Generalized-activated Deep Double Deterministic Policy Gradients

It is vital to accurately estimate the value function in Deep Reinforcement Learning (DRL) such that the agent could execute proper actions instead of suboptimal ones. However, existing actor-critic methods suffer more or less from underestimation bias or overestimation bias, which negatively affect their performance. In this paper, we reveal a simple but effective principle: proper value correction benefits bias alleviation, where we propose the generalized-activated weighting operator that uses any non-decreasing function, namely activation function, as weights for better value estimation. Particularly, we integrate the generalized-activated weighting operator into value estimation and introduce a novel algorithm, Generalized-activated Deep Double Deterministic Policy Gradients (GD3). We theoretically show that GD3 is capable of alleviating the potential estimation bias. We interestingly find that simple activation functions lead to satisfying performance with no additional tricks, and could contribute to faster convergence. Experimental results on numerous challenging continuous control tasks show that GD3 with task-specific activation outperforms the common baseline methods. We also uncover a fact that fine-tuning the polynomial activation function achieves superior results on most of the tasks.

cs.LG↗

Implicit Feature Refinement for Instance Segmentation

We propose a novel implicit feature refinement module for high-quality instance segmentation. Existing image/video instance segmentation methods rely on explicitly stacked convolutions to refine instance features before the final prediction. In this paper, we first give an empirical comparison of different refinement strategies,which reveals that the widely-used four consecutive convolutions are not necessary. As an alternative, weight-sharing convolution blocks provides competitive performance. When such block is iterated for infinite times, the block output will eventually convergeto an equilibrium state. Based on this observation, the implicit feature refinement (IFR) is developed by constructing an implicit function. The equilibrium state of instance features can be obtained by fixed-point iteration via a simulated infinite-depth network. Our IFR enjoys several advantages: 1) simulates an infinite-depth refinement network while only requiring parameters of single residual block; 2) produces high-level equilibrium instance features of global receptive field; 3) serves as a plug-and-play general module easily extended to most object recognition frameworks. Experiments on the COCO and YouTube-VIS benchmarks show that our IFR achieves improved performance on state-of-the-art image/video instance segmentation frameworks, while reducing the parameter burden (e.g.1% AP improvement on Mask R-CNN with only 30.0% parameters in mask head). Code is made available at https://github.com/lufanma/IFR.git

cs.CV↗

A Coarse-to-Fine Instance Segmentation Network with Learning Boundary Representation

Boundary-based instance segmentation has drawn much attention since of its attractive efficiency. However, existing methods suffer from the difficulty in long-distance regression. In this paper, we propose a coarse-to-fine module to address the problem. Approximate boundary points are generated at the coarse stage and then features of these points are sampled and fed to a refined regressor for fine prediction. It is end-to-end trainable since differential sampling operation is well supported in the module. Furthermore, we design a holistic boundary-aware branch and introduce instance-agnostic supervision to assist regression. Equipped with ResNet-101, our approach achieves 31.7\% mask AP on COCO dataset with single-scale training and testing, outperforming the baseline 1.3\% mask AP with less than 1\% additional parameters and GFLOPs. Experiments also show that our proposed method achieves competitive performance compared to existing boundary-based methods with a lightweight design and a simple pipeline.

cs.CV↗

Efficient Continuous Control with Double Actors and Regularized Critics

How to obtain good value estimation is one of the key problems in Reinforcement Learning (RL). Current value estimation methods, such as DDPG and TD3, suffer from unnecessary over- or underestimation bias. In this paper, we explore the potential of double actors, which has been neglected for a long time, for better value function estimation in continuous setting. First, we uncover and demonstrate the bias alleviation property of double actors by building double actors upon single critic and double critics to handle overestimation bias in DDPG and underestimation bias in TD3 respectively. Next, we interestingly find that double actors help improve the exploration ability of the agent. Finally, to mitigate the uncertainty of value estimate from double critics, we further propose to regularize the critic networks under double actors architecture, which gives rise to Double Actors Regularized Critics (DARC) algorithm. Extensive experimental results on challenging continuous control tasks show that DARC significantly outperforms state-of-the-art methods with higher sample efficiency.

cs.LG↗

F3RNet: Full-Resolution Residual Registration Network for Deformable Image Registration

Deformable image registration (DIR) is essential for many image-guided therapies. Recently, deep learning approaches have gained substantial popularity and success in DIR. Most deep learning approaches use the so-called mono-stream "high-to-low, low-to-high" network structure, and can achieve satisfactory overall registration results. However, accurate alignments for some severely deformed local regions, which are crucial for pinpointing surgical targets, are often overlooked. Consequently, these approaches are not sensitive to some hard-to-align regions, e.g., intra-patient registration of deformed liver lobes. In this paper, we propose a novel unsupervised registration network, namely the Full-Resolution Residual Registration Network (F3RNet), for deformable registration of severely deformed organs. The proposed method combines two parallel processing streams in a residual learning fashion. One stream takes advantage of the full-resolution information that facilitates accurate voxel-level registration. The other stream learns the deep multi-scale residual representations to obtain robust recognition. We also factorize the 3D convolution to reduce the training parameters and enhance network efficiency. We validate the proposed method on a clinically acquired intra-patient abdominal CT-MRI dataset and a public inspiratory and expiratory thorax CT dataset. Experiments on both multimodal and unimodal registration demonstrate promising results compared to state-of-the-art approaches.

eess.IV↗

Unimodal Cyclic Regularization for Training Multimodal Image Registration Networks

The loss function of an unsupervised multimodal image registration framework has two terms, i.e., a metric for similarity measure and regularization. In the deep learning era, researchers proposed many approaches to automatically learn the similarity metric, which has been shown effective in improving registration performance. However, for the regularization term, most existing multimodal registration approaches still use a hand-crafted formula to impose artificial properties on the estimated deformation field. In this work, we propose a unimodal cyclic regularization training pipeline, which learns task-specific prior knowledge from simpler unimodal registration, to constrain the deformation field of multimodal registration. In the experiment of abdominal CT-MR registration, the proposed method yields better results over conventional regularization methods, especially for severely deformed local regions.

cs.CV↗

Unsupervised Multimodal Image Registration with Adaptative Gradient Guidance

Multimodal image registration (MIR) is a fundamental procedure in many image-guided therapies. Recently, unsupervised learning-based methods have demonstrated promising performance over accuracy and efficiency in deformable image registration. However, the estimated deformation fields of the existing methods fully rely on the to-be-registered image pair. It is difficult for the networks to be aware of the mismatched boundaries, resulting in unsatisfactory organ boundary alignment. In this paper, we propose a novel multimodal registration framework, which leverages the deformation fields estimated from both: (i) the original to-be-registered image pair, (ii) their corresponding gradient intensity maps, and adaptively fuses them with the proposed gated fusion module. With the help of auxiliary gradient-space guidance, the network can concentrate more on the spatial relationship of the organ boundary. Experimental results on two clinically acquired CT-MRI datasets demonstrate the effectiveness of our proposed approach.

cs.CV↗

Adversarial Uni- and Multi-modal Stream Networks for Multimodal Image Registration

Deformable image registration between Computed Tomography (CT) images and Magnetic Resonance (MR) imaging is essential for many image-guided therapies. In this paper, we propose a novel translation-based unsupervised deformable image registration method. Distinct from other translation-based methods that attempt to convert the multimodal problem (e.g., CT-to-MR) into a unimodal problem (e.g., MR-to-MR) via image-to-image translation, our method leverages the deformation fields estimated from both: (i) the translated MR image and (ii) the original CT image in a dual-stream fashion, and automatically learns how to fuse them to achieve better registration performance. The multimodal registration network can be effectively trained by computationally efficient similarity metrics without any ground-truth deformation. Our method has been evaluated on two clinical datasets and demonstrates promising results compared to state-of-the-art traditional and learning-based methods.

eess.IV↗

Match4Rec: A Novel Recommendation Algorithm Based on Bidirectional Encoder Representation with the Matching Task

Characterizing users' interests accurately plays a significant role in an effective recommender system. The sequential recommender system can learn powerful hidden representations of users from successive user-item interactions and dynamic users' preferences. To analyze such sequential data, conventional methods mainly include Markov Chains (MCs) and Recurrent Neural Networks (RNNs). Recently, the use of self-attention mechanisms and bi-directional architectures have gained much attention. However, there still exists a major limitation in previous works that they only model the user's main purposes in the behavioral sequences separately and locally, and they lack the global representation of the user's whole sequential behavior. To address this limitation, we propose a novel bidirectional sequential recommendation algorithm that integrates the user's local purposes with the global preference by additive supervision of the matching task. We combine the mask task with the matching task in the training process of the bidirectional encoder. A new sample production method is also introduced to alleviate the effect of mask noise. Our proposed model can not only learn bidirectional semantics from users' behavioral sequences but also explicitly produces user representations to capture user's global preference. Extensive empirical studies demonstrate our approach considerably outperforms various state-of-the-art models.

cs.SI↗