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Jianqing Fan

Publications and source records attributed to Jianqing Fan.

At least 145 records · Page 8Linked to original sources

Principal component analysis for big data

Big data is transforming our world, revolutionizing operations and analytics everywhere, from financial engineering to biomedical sciences. The complexity of big data often makes dimension reduction techniques necessary before conducting statistical inference. Principal component analysis, commonly referred to as PCA, has become an essential tool for multivariate data analysis and unsupervised dimension reduction, the goal of which is to find a lower dimensional subspace that captures most of the variation in the dataset. This article provides an overview of methodological and theoretical developments of PCA over the last decade, with focus on its applications to big data analytics. We first review the mathematical formulation of PCA and its theoretical development from the view point of perturbation analysis. We then briefly discuss the relationship between PCA and factor analysis as well as its applications to large covariance estimation and multiple testing. PCA also finds important applications in many modern machine learning problems, and we focus on community detection, ranking, mixture model and manifold learning in this paper.

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A New Perspective on Robust $M$-Estimation: Finite Sample Theory and Applications to Dependence-Adjusted Multiple Testing

Heavy-tailed errors impair the accuracy of the least squares estimate, which can be spoiled by a single grossly outlying observation. As argued in the seminal work of Peter Huber in 1973 [{\it Ann. Statist.} {\bf 1} (1973) 799--821], robust alternatives to the method of least squares are sorely needed. To achieve robustness against heavy-tailed sampling distributions, we revisit the Huber estimator from a new perspective by letting the tuning parameter involved diverge with the sample size. In this paper, we develop nonasymptotic concentration results for such an adaptive Huber estimator, namely, the Huber estimator with the tuning parameter adapted to sample size, dimension, and the variance of the noise. Specifically, we obtain a sub-Gaussian-type deviation inequality and a nonasymptotic Bahadur representation when noise variables only have finite second moments. The nonasymptotic results further yield two conventional normal approximation results that are of independent interest, the Berry-Esseen inequality and Cramér-type moderate deviation. As an important application to large-scale simultaneous inference, we apply these robust normal approximation results to analyze a dependence-adjusted multiple testing procedure for moderately heavy-tailed data. It is shown that the robust dependence-adjusted procedure asymptotically controls the overall false discovery proportion at the nominal level under mild moment conditions. Thorough numerical results on both simulated and real datasets are also provided to back up our theory.

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Generalized High-Dimensional Trace Regression via Nuclear Norm Regularization

We study the generalized trace regression with a near low-rank regression coefficient matrix, which extends notion of sparsity for regression coefficient vectors. Specifically, given a matrix covariate $X$, the probability density function $f(Y\vert X)=c(Y)\exp{(ϕ^{-1}\left[-Yη^* + b(η^*)\right])}$, where $η^*=tr({Θ^*}^TX)$. This model accommodates various types of responses and embraces many important problem setups such as reduced-rank regression, matrix regression that accommodates a panel of regressors, matrix completion, among others. We estimate $Θ^*$ through minimizing empirical negative log-likelihood plus nuclear norm penalty. We first establish a general theory and then for each specific problem, we derive explicitly the statistical rate of the proposed estimator. They all match the minimax rates in the linear trace regression up to logarithmic factors. Numerical studies confirm the rates we established and demonstrate the advantage of generalized trace regression over linear trace regression when the response is dichotomous. We also show the benefit of incorporating nuclear norm regularization in dynamic stock return prediction and in image classification.

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Partial Consistency with Sparse Incidental Parameters

Penalized estimation principle is fundamental to high-dimensional problems. In the literature, it has been extensively and successfully applied to various models with only structural parameters. As a contrast, in this paper, we apply this penalization principle to a linear regression model with a finite-dimensional vector of structural parameters and a high-dimensional vector of sparse incidental parameters. For the estimators of the structural parameters, we derive their consistency and asymptotic normality, which reveals an oracle property. However, the penalized estimators for the incidental parameters possess only partial selection consistency but not consistency. This is an interesting partial consistency phenomenon: the structural parameters are consistently estimated while the incidental ones cannot. For the structural parameters, also considered is an alternative two-step penalized estimator, which has fewer possible asymptotic distributions and thus is more suitable for statistical inferences. We further extend the methods and results to the case where the dimension of the structural parameter vector diverges with but slower than the sample size. A data-driven approach for selecting a penalty regularization parameter is provided. The finite-sample performance of the penalized estimators for the structural parameters is evaluated by simulations and a real data set is analyzed.

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Are Discoveries Spurious? Distributions of Maximum Spurious Correlations and Their Applications

Over the last two decades, many exciting variable selection methods have been developed for finding a small group of covariates that are associated with the response from a large pool. Can the discoveries from these data mining approaches be spurious due to high dimensionality and limited sample size? Can our fundamental assumptions about the exogeneity of the covariates needed for such variable selection be validated with the data? To answer these questions, we need to derive the distributions of the maximum spurious correlations given a certain number of predictors, namely, the distribution of the correlation of a response variable $Y$ with the best $s$ linear combinations of $p$ covariates $\mathbf{X}$, even when $\mathbf{X}$ and $Y$ are independent. When the covariance matrix of $\mathbf{X}$ possesses the restricted eigenvalue property, we derive such distributions for both a finite $s$ and a diverging $s$, using Gaussian approximation and empirical process techniques. However, such a distribution depends on the unknown covariance matrix of $\mathbf{X}$. Hence, we use the multiplier bootstrap procedure to approximate the unknown distributions and establish the consistency of such a simple bootstrap approach. The results are further extended to the situation where the residuals are from regularized fits. Our approach is then used to construct the upper confidence limit for the maximum spurious correlation and to test the exogeneity of the covariates. The former provides a baseline for guarding against false discoveries and the latter tests whether our fundamental assumptions for high-dimensional model selection are statistically valid. Our techniques and results are illustrated with both numerical examples and real data analysis.

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An $\ell_{\infty}$ Eigenvector Perturbation Bound and Its Application to Robust Covariance Estimation

In statistics and machine learning, people are often interested in the eigenvectors (or singular vectors) of certain matrices (e.g. covariance matrices, data matrices, etc). However, those matrices are usually perturbed by noises or statistical errors, either from random sampling or structural patterns. One usually employs Davis-Kahan $\sin θ$ theorem to bound the difference between the eigenvectors of a matrix $A$ and those of a perturbed matrix $\widetilde{A} = A + E$, in terms of $\ell_2$ norm. In this paper, we prove that when $A$ is a low-rank and incoherent matrix, the $\ell_{\infty}$ norm perturbation bound of singular vectors (or eigenvectors in the symmetric case) is smaller by a factor of $\sqrt{d_1}$ or $\sqrt{d_2}$ for left and right vectors, where $d_1$ and $d_2$ are the matrix dimensions. The power of this new perturbation result is shown in robust covariance estimation, particularly when random variables have heavy tails. There, we propose new robust covariance estimators and establish their asymptotic properties using the newly developed perturbation bound. Our theoretical results are verified through extensive numerical experiments.

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A Shrinkage Principle for Heavy-Tailed Data: High-Dimensional Robust Low-Rank Matrix Recovery

This paper introduces a simple principle for robust high-dimensional statistical inference via an appropriate shrinkage on the data. This widens the scope of high-dimensional techniques, reducing the moment conditions from sub-exponential or sub-Gaussian distributions to merely bounded second or fourth moment. As an illustration of this principle, we focus on robust estimation of the low-rank matrix $Θ^*$ from the trace regression model $Y=Tr (Θ^{*T}X) +ε$. It encompasses four popular problems: sparse linear models, compressed sensing, matrix completion and multi-task regression. We propose to apply penalized least-squares approach to appropriately truncated or shrunk data. Under only bounded $2+δ$ moment condition on the response, the proposed robust methodology yields an estimator that possesses the same statistical error rates as previous literature with sub-Gaussian errors. For sparse linear models and multi-tasking regression, we further allow the design to have only bounded fourth moment and obtain the same statistical rates, again, by appropriate shrinkage of the design matrix. As a byproduct, we give a robust covariance matrix estimator and establish its concentration inequality in terms of the spectral norm when the random samples have only bounded fourth moment. Extensive simulations have been carried out to support our theories.

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I-LAMM for Sparse Learning: Simultaneous Control of Algorithmic Complexity and Statistical Error

We propose a computational framework named iterative local adaptive majorize-minimization (I-LAMM) to simultaneously control algorithmic complexity and statistical error when fitting high dimensional models. I-LAMM is a two-stage algorithmic implementation of the local linear approximation to a family of folded concave penalized quasi-likelihood. The first stage solves a convex program with a crude precision tolerance to obtain a coarse initial estimator, which is further refined in the second stage by iteratively solving a sequence of convex programs with smaller precision tolerances. Theoretically, we establish a phase transition: the first stage has a sublinear iteration complexity, while the second stage achieves an improved linear rate of convergence. Though this framework is completely algorithmic, it provides solutions with optimal statistical performances and controlled algorithmic complexity for a large family of nonconvex optimization problems. The iteration effects on statistical errors are clearly demonstrated via a contraction property. Our theory relies on a localized version of the sparse/restricted eigenvalue condition, which allows us to analyze a large family of loss and penalty functions and provide optimality guarantees under very weak assumptions (For example, I-LAMM requires much weaker minimal signal strength than other procedures). Thorough numerical results are provided to support the obtained theory.

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Embracing the Blessing of Dimensionality in Factor Models

Factor modeling is an essential tool for exploring intrinsic dependence structures among high-dimensional random variables. Much progress has been made for estimating the covariance matrix from a high-dimensional factor model. However, the blessing of dimensionality has not yet been fully embraced in the literature: much of the available data is often ignored in constructing covariance matrix estimates. If our goal is to accurately estimate a covariance matrix of a set of targeted variables, shall we employ additional data, which are beyond the variables of interest, in the estimation? In this paper, we provide sufficient conditions for an affirmative answer, and further quantify its gain in terms of Fisher information and convergence rate. In fact, even an oracle-like result (as if all the factors were known) can be achieved when a sufficiently large number of variables is used. The idea of utilizing data as much as possible brings computational challenges. A divide-and-conquer algorithm is thus proposed to alleviate the computational burden, and also shown not to sacrifice any statistical accuracy in comparison with a pooled analysis. Simulation studies further confirm our advocacy for the use of full data, and demonstrate the effectiveness of the above algorithm. Our proposal is applied to a microarray data example that shows empirical benefits of using more data.

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Guarding against Spurious Discoveries in High Dimensions

Many data mining and statistical machine learning algorithms have been developed to select a subset of covariates to associate with a response variable. Spurious discoveries can easily arise in high-dimensional data analysis due to enormous possibilities of such selections. How can we know statistically our discoveries better than those by chance? In this paper, we define a measure of goodness of spurious fit, which shows how good a response variable can be fitted by an optimally selected subset of covariates under the null model, and propose a simple and effective LAMM algorithm to compute it. It coincides with the maximum spurious correlation for linear models and can be regarded as a generalized maximum spurious correlation. We derive the asymptotic distribution of such goodness of spurious fit for generalized linear models and $L_1$ regression. Such an asymptotic distribution depends on the sample size, ambient dimension, the number of variables used in the fit, and the covariance information. It can be consistently estimated by multiplier bootstrapping and used as a benchmark to guard against spurious discoveries. It can also be applied to model selection, which considers only candidate models with goodness of fits better than those by spurious fits. The theory and method are convincingly illustrated by simulated examples and an application to the binary outcomes from German Neuroblastoma Trials.

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Structured Correlation Detection with Application to Colocalization Analysis in Dual-Channel Fluorescence Microscopic Imaging

Motivated by the problem of colocalization analysis in fluorescence microscopic imaging, we study in this paper structured detection of correlated regions between two random processes observed on a common domain. We argue that although intuitive, direct use of the maximum log-likelihood statistic suffers from potential bias and substantially reduced power, and introduce a simple size-based normalization to overcome this problem. We show that scanning with the proposed size-corrected likelihood ratio statistics leads to optimal correlation detection over a large collection of structured correlation detection problems.

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Heterogeneity Adjustment with Applications to Graphical Model Inference

Heterogeneity is an unwanted variation when analyzing aggregated datasets from multiple sources. Though different methods have been proposed for heterogeneity adjustment, no systematic theory exists to justify these methods. In this work, we propose a generic framework named ALPHA (short for Adaptive Low-rank Principal Heterogeneity Adjustment) to model, estimate, and adjust heterogeneity from the original data. Once the heterogeneity is adjusted, we are able to remove the biases of batch effects and to enhance the inferential power by aggregating the homogeneous residuals from multiple sources. Under a pervasive assumption that the latent heterogeneity factors simultaneously affect a large fraction of observed variables, we provide a rigorous theory to justify the proposed framework. Our framework also allows the incorporation of informative covariates and appeals to the "Bless of Dimensionality". As an illustrative application of this generic framework, we consider a problem of estimating high-dimensional precision matrix for graphical model inference based on multiple datasets. We also provide thorough numerical studies on both synthetic datasets and a brain imaging dataset to demonstrate the efficacy of the developed theory and methods.

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Robust Covariance Estimation for Approximate Factor Models

In this paper, we study robust covariance estimation under the approximate factor model with observed factors. We propose a novel framework to first estimate the initial joint covariance matrix of the observed data and the factors, and then use it to recover the covariance matrix of the observed data. We prove that once the initial matrix estimator is good enough to maintain the element-wise optimal rate, the whole procedure will generate an estimated covariance with desired properties. For data with only bounded fourth moments, we propose to use Huber loss minimization to give the initial joint covariance estimation. This approach is applicable to a much wider range of distributions, including sub-Gaussian and elliptical distributions. We also present an asymptotic result for Huber's M-estimator with a diverging parameter. The conclusions are demonstrated by extensive simulations and real data analysis.

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Projected principal component analysis in factor models

This paper introduces a Projected Principal Component Analysis (Projected-PCA), which employs principal component analysis to the projected (smoothed) data matrix onto a given linear space spanned by covariates. When it applies to high-dimensional factor analysis, the projection removes noise components. We show that the unobserved latent factors can be more accurately estimated than the conventional PCA if the projection is genuine, or more precisely, when the factor loading matrices are related to the projected linear space. When the dimensionality is large, the factors can be estimated accurately even when the sample size is finite. We propose a flexible semiparametric factor model, which decomposes the factor loading matrix into the component that can be explained by subject-specific covariates and the orthogonal residual component. The covariates' effects on the factor loadings are further modeled by the additive model via sieve approximations. By using the newly proposed Projected-PCA, the rates of convergence of the smooth factor loading matrices are obtained, which are much faster than those of the conventional factor analysis. The convergence is achieved even when the sample size is finite and is particularly appealing in the high-dimension-low-sample-size situation. This leads us to developing nonparametric tests on whether observed covariates have explaining powers on the loadings and whether they fully explain the loadings. The proposed method is illustrated by both simulated data and the returns of the components of the S&P 500 index.

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Sufficient Forecasting Using Factor Models

We consider forecasting a single time series when there is a large number of predictors and a possible nonlinear effect. The dimensionality was first reduced via a high-dimensional (approximate) factor model implemented by the principal component analysis. Using the extracted factors, we develop a novel forecasting method called the sufficient forecasting, which provides a set of sufficient predictive indices, inferred from high-dimensional predictors, to deliver additional predictive power. The projected principal component analysis will be employed to enhance the accuracy of inferred factors when a semi-parametric (approximate) factor model is assumed. Our method is also applicable to cross-sectional sufficient regression using extracted factors. The connection between the sufficient forecasting and the deep learning architecture is explicitly stated. The sufficient forecasting correctly estimates projection indices of the underlying factors even in the presence of a nonparametric forecasting function. The proposed method extends the sufficient dimension reduction to high-dimensional regimes by condensing the cross-sectional information through factor models. We derive asymptotic properties for the estimate of the central subspace spanned by these projection directions as well as the estimates of the sufficient predictive indices. We further show that the natural method of running multiple regression of target on estimated factors yields a linear estimate that actually falls into this central subspace. Our method and theory allow the number of predictors to be larger than the number of observations. We finally demonstrate that the sufficient forecasting improves upon the linear forecasting in both simulation studies and an empirical study of forecasting macroeconomic variables.

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Regularity Properties for Sparse Regression

Statistical and machine learning theory has developed several conditions ensuring that popular estimators such as the Lasso or the Dantzig selector perform well in high-dimensional sparse regression, including the restricted eigenvalue, compatibility, and $\ell_q$ sensitivity properties. However, some of the central aspects of these conditions are not well understood. For instance, it is unknown if these conditions can be checked efficiently on any given data set. This is problematic, because they are at the core of the theory of sparse regression. Here we provide a rigorous proof that these conditions are NP-hard to check. This shows that the conditions are computationally infeasible to verify, and raises some questions about their practical applications. However, by taking an average-case perspective instead of the worst-case view of NP-hardness, we show that a particular condition, $\ell_q$ sensitivity, has certain desirable properties. This condition is weaker and more general than the others. We show that it holds with high probability in models where the parent population is well behaved, and that it is robust to certain data processing steps. These results are desirable, as they provide guidance about when the condition, and more generally the theory of sparse regression, may be relevant in the analysis of high-dimensional correlated observational data.

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Estimation of functionals of sparse covariance matrices

High-dimensional statistical tests often ignore correlations to gain simplicity and stability leading to null distributions that depend on functionals of correlation matrices such as their Frobenius norm and other $\ell_r$ norms. Motivated by the computation of critical values of such tests, we investigate the difficulty of estimation the functionals of sparse correlation matrices. Specifically, we show that simple plug-in procedures based on thresholded estimators of correlation matrices are sparsity-adaptive and minimax optimal over a large class of correlation matrices. Akin to previous results on functional estimation, the minimax rates exhibit an elbow phenomenon. Our results are further illustrated in simulated data as well as an empirical study of data arising in financial econometrics.

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Distributed Estimation and Inference with Statistical Guarantees

This paper studies hypothesis testing and parameter estimation in the context of the divide and conquer algorithm. In a unified likelihood based framework, we propose new test statistics and point estimators obtained by aggregating various statistics from $k$ subsamples of size $n/k$, where $n$ is the sample size. In both low dimensional and high dimensional settings, we address the important question of how to choose $k$ as $n$ grows large, providing a theoretical upper bound on $k$ such that the information loss due to the divide and conquer algorithm is negligible. In other words, the resulting estimators have the same inferential efficiencies and estimation rates as a practically infeasible oracle with access to the full sample. Thorough numerical results are provided to back up the theory.

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