arXiv subjects

Jiaqi Ding

Publications and source records attributed to Jiaqi Ding.

11 recordsLinked to original sources

arXiv2026

LangBP: Language-Guided Reasoning and Acting for Joint Bidding and Pricing

Auto-bidding is a long-horizon sequential decision problem for maximizing conversion value under budget and key performance indicator (KPI) constraints. Recent work extends this task from bidding alone to joint bidding and pricing, where a policy controls bidding decisions and pricing corrections. Existing methods mainly rely on numerical trajectory modeling, which offers limited support for interpreting campaign context and expressing high-level strategies. Large language models (LLMs) can complement this paradigm with their reasoning capabilities. However, existing language-guided methods have two limitations. First, they condition actions on language strategies without modeling the corresponding state changes, making it difficult to distinguish errors in strategy understanding from errors in action generation. Second, different instructions can produce similar execution effects, leading to imbalanced policy updates across effects. We propose LangBP, a hierarchical framework for language-guided joint bidding and pricing. LangBP's Semantic Decision Transformer (S-DT) predicts target states from the instruction and the trajectory history, then recovers the joint action via inverse dynamics. We further propose Execution-Grouped Policy Optimization (EGPO), which scores candidate effects with a Context--Effect Verifier (CEV) and balances policy updates across effect groups. Experiments on AuctionNet show that LangBP outperforms strong baselines, and online A/B tests further demonstrate business gains in real-world deployment on a large-scale e-commerce platform.

cs.GT↗

arXiv2026

SPACE: Source-free Proxy Anchor Concept Erasure for MLLMs

As Multimodal Large Language Models (MLLMs) face growing privacy risks and regulatory constraints, machine unlearning (MU) has emerged as a crucial solution for removing sensitive data while preserving model performance. However, existing MU methods typically rely on visual data of the target concepts, which is often unavailable due to strict data retention policies, thus creating a demand for source-free unlearning approaches that operate without access to the target data. In this work, we propose Source-free Proxy Anchor Concept Erasure (SPACE), the first source-free unlearning framework specialized for MLLMs. SPACE consists of two stages: (1) Text-Guided Proxy Anchor Selection (TPAS), which retrieves semantically aligned proxy anchors from the shared feature space. (2) Dual-Constraint Semantic Isolation (DCSI), which optimizes these anchors to indirectly erase target concepts. DCSI confines updates to the null space of retained knowledge, ensuring structural integrity. We theoretically prove that SPACE strictly bounds the perturbation on retained knowledge and maximizes feature spectral entropy, thereby maintaining the model's performance. Furthermore, extensive experiments across six datasets show that SPACE achieves performance comparable to that of state-of-the-art data-dependent methods, validating its effectiveness in source-free MU scenarios. The source code will be released.

cs.LG↗

arXiv2026

Matrix-Response Generalized Linear Mixed Model with Applications to Longitudinal Brain Images

Longitudinal brain imaging data facilitate the monitoring of structural and functional alterations in individual brains across time, offering essential understanding of dynamic neurobiological mechanisms. Such data improve sensitivity for detecting early biomarkers of disease progression and enhance the evaluation of intervention effects. While recent matrix-response regression models can relate static brain networks to external predictors, there remain few statistical methods for longitudinal brain networks, especially those derived from high-dimensional imaging data. We introduce a matrix-response generalized linear mixed model that accommodates longitudinal brain networks and identifies edges whose connectivity is influenced by external predictors. An efficient Monte Carlo Expectation-Maximization algorithm is developed for parameter estimation. Extensive simulations demonstrate effective identification of covariate-related network components and accurate parameter estimation. We further demonstrate the usage of the proposed method through applications to diffusion tensor imaging (DTI) and functional MRI (fMRI) datasets.

stat.AP↗

arXiv2026

GeoDynamics: A Geometric State-Space Neural Network for Understanding Brain Dynamics on Riemannian Manifolds

State-space models (SSMs) have become a cornerstone for unraveling brain dynamics, revealing how latent neural states evolve over time and give rise to observed signals. By combining the flexibility of deep learning with the principled dynamical structure of SSMs, recent studies have achieved powerful fits to functional neuroimaging data. However, most existing approaches still view the brain as a set of loosely connected regions or impose oversimplified network priors, falling short of a truly holistic and self-organized dynamical system perspective. Brain functional connectivity (FC) at each time point naturally forms a symmetric positive definite (SPD) matrix, which resides on a curved Riemannian manifold rather than in Euclidean space. Capturing the trajectories of these SPD matrices is key to understanding how coordinated networks support cognition and behavior. To this end, we introduce GeoDynamics, a geometric state-space neural network that tracks latent brain-state trajectories directly on the high-dimensional SPD manifold. GeoDynamics embeds each connectivity matrix into a manifold-aware recurrent framework, learning smooth and geometry-respecting transitions that reveal task-driven state changes and early markers of Alzheimer's disease, Parkinson's disease, and autism. Beyond neuroscience, we validate GeoDynamics on human action recognition benchmarks (UTKinect, Florence, HDM05), demonstrating its scalability and robustness in modeling complex spatiotemporal dynamics across diverse domains.

cs.LG↗

arXiv2026

Explore Brain-Inspired Machine Intelligence for Connecting Dots on Graphs Through Holographic Blueprint of Oscillatory Synchronization

Neural coupling in both neuroscience and artificial intelligence emerges as dynamic oscillatory patterns that encode abstract concepts. To this end, we hypothesize that a deeper understanding of the neural mechanisms governing brain rhythms can inspire next-generation design principles for machine learning algorithms, leading to improved efficiency and robustness. Building on this idea, we first model evolving brain rhythms through the interference of spontaneously synchronized neural oscillations, termed HoloBrain. The success of modeling brain rhythms using an artificial dynamical system of coupled oscillations motivates a "first principle" for brain-inspired machine intelligence based on a shared synchronization mechanism, termed HoloGraph. This principle enables graph neural networks to move beyond conventional heat diffusion paradigms toward modeling oscillatory synchronization. Our HoloGraph framework not only effectively mitigates the over-smoothing problem in graph neural networks but also demonstrates strong potential for reasoning and solving challenging problems on graphs.

q-bio.NC↗

arXiv2025

Understanding Mechanistic Role of Structural and Functional Connectivity in Tau Propagation Through Multi-Layer Modeling

Emerging neuroimaging evidence shows that pathological tau proteins build up along specific brain networks, suggesting that large-scale network architecture plays a key role in the progression of Alzheimer's disease (AD). However, how structural connectivity (SC) and functional connectivity (FC) interact to influence tau propagation remains unclear. Leveraging an unprecedented volume of longitudinal neuroimaging data, we examine SC-FC interactions through a multi-layer graph diffusion model. Beyond showing that connectome architecture constrains tau spread, our model reveals a regionally asymmetric contribution of SC and FC. Specifically, FC predominantly drives tau spread in subcortical areas, the insula, frontal and temporal cortices, whereas SC plays a larger role in occipital, parietal, and limbic regions. The relative dominance of SC versus FC shifts over the course of disease, with FC generally prevailing in early AD and SC becoming primary in later stages. Spatial patterns of SC- and FC-dominant regions strongly align with the regional expression of AD-associated genes involved in inflammation, apoptosis, and lysosomal function, including CHUK (IKK-alpha), TMEM106B, MCL1, NOTCH1, and TH. In parallel, other non-modifiable risk factors (e.g., APOE genotype, sex) and biological mechanisms (e.g., amyloid deposition) selectively reshape tau propagation by shifting dominant routes between anatomical and functional pathways in a region-specific manner. Findings are validated in an independent AD cohort.

cs.LG↗

arXiv2025

BrainMAP: Learning Multiple Activation Pathways in Brain Networks

Functional Magnetic Resonance Image (fMRI) is commonly employed to study human brain activity, since it offers insight into the relationship between functional fluctuations and human behavior. To enhance analysis and comprehension of brain activity, Graph Neural Networks (GNNs) have been widely applied to the analysis of functional connectivities (FC) derived from fMRI data, due to their ability to capture the synergistic interactions among brain regions. However, in the human brain, performing complex tasks typically involves the activation of certain pathways, which could be represented as paths across graphs. As such, conventional GNNs struggle to learn from these pathways due to the long-range dependencies of multiple pathways. To address these challenges, we introduce a novel framework BrainMAP to learn Multiple Activation Pathways in Brain networks. BrainMAP leverages sequential models to identify long-range correlations among sequentialized brain regions and incorporates an aggregation module based on Mixture of Experts (MoE) to learn from multiple pathways. Our comprehensive experiments highlight BrainMAP's superior performance. Furthermore, our framework enables explanatory analyses of crucial brain regions involved in tasks. Our code is provided at https://github.com/LzyFischer/Graph-Mamba.

cs.AI↗

arXiv2024

NeuroPath: A Neural Pathway Transformer for Joining the Dots of Human Connectomes

Although modern imaging technologies allow us to study connectivity between two distinct brain regions in-vivo, an in-depth understanding of how anatomical structure supports brain function and how spontaneous functional fluctuations emerge remarkable cognition is still elusive. Meanwhile, tremendous efforts have been made in the realm of machine learning to establish the nonlinear mapping between neuroimaging data and phenotypic traits. However, the absence of neuroscience insight in the current approaches poses significant challenges in understanding cognitive behavior from transient neural activities. To address this challenge, we put the spotlight on the coupling mechanism of structural connectivity (SC) and functional connectivity (FC) by formulating such network neuroscience question into an expressive graph representation learning problem for high-order topology. Specifically, we introduce the concept of topological detour to characterize how a ubiquitous instance of FC (direct link) is supported by neural pathways (detour) physically wired by SC, which forms a cyclic loop interacted by brain structure and function. In the cliché of machine learning, the multi-hop detour pathway underlying SC-FC coupling allows us to devise a novel multi-head self-attention mechanism within Transformer to capture multi-modal feature representation from paired graphs of SC and FC. Taken together, we propose a biological-inspired deep model, coined as NeuroPath, to find putative connectomic feature representations from the unprecedented amount of neuroimages, which can be plugged into various downstream applications such as task recognition and disease diagnosis. We have evaluated NeuroPath on large-scale public datasets including HCP and UK Biobank under supervised and zero-shot learning, where the state-of-the-art performance by our NeuroPath indicates great potential in network neuroscience.

q-bio.NC↗

arXiv2024

Machine Learning on Dynamic Functional Connectivity: Promise, Pitfalls, and Interpretations

An unprecedented amount of existing functional Magnetic Resonance Imaging (fMRI) data provides a new opportunity to understand the relationship between functional fluctuation and human cognition/behavior using a data-driven approach. To that end, tremendous efforts have been made in machine learning to predict cognitive states from evolving volumetric images of blood-oxygen-level-dependent (BOLD) signals. Due to the complex nature of brain function, however, the evaluation on learning performance and discoveries are not often consistent across current state-of-the-arts (SOTA). By capitalizing on large-scale existing neuroimaging data (34,887 data samples from six public databases), we seek to establish a well-founded empirical guideline for designing deep models for functional neuroimages by linking the methodology underpinning with knowledge from the neuroscience domain. Specifically, we put the spotlight on (1) What is the current SOTA performance in cognitive task recognition and disease diagnosis using fMRI? (2) What are the limitations of current deep models? and (3) What is the general guideline for selecting the suitable machine learning backbone for new neuroimaging applications? We have conducted a comprehensive evaluation and statistical analysis, in various settings, to answer the above outstanding questions.

cs.LG↗

arXiv2023

Re-Think and Re-Design Graph Neural Networks in Spaces of Continuous Graph Diffusion Functionals

Graph neural networks (GNNs) are widely used in domains like social networks and biological systems. However, the locality assumption of GNNs, which limits information exchange to neighboring nodes, hampers their ability to capture long-range dependencies and global patterns in graphs. To address this, we propose a new inductive bias based on variational analysis, drawing inspiration from the Brachistochrone problem. Our framework establishes a mapping between discrete GNN models and continuous diffusion functionals. This enables the design of application-specific objective functions in the continuous domain and the construction of discrete deep models with mathematical guarantees. To tackle over-smoothing in GNNs, we analyze the existing layer-by-layer graph embedding models and identify that they are equivalent to l2-norm integral functionals of graph gradients, which cause over-smoothing. Similar to edge-preserving filters in image denoising, we introduce total variation (TV) to align the graph diffusion pattern with global community topologies. Additionally, we devise a selective mechanism to address the trade-off between model depth and over-smoothing, which can be easily integrated into existing GNNs. Furthermore, we propose a novel generative adversarial network (GAN) that predicts spreading flows in graphs through a neural transport equation. To mitigate vanishing flows, we customize the objective function to minimize transportation within each community while maximizing inter-community flows. Our GNN models achieve state-of-the-art (SOTA) performance on popular graph learning benchmarks such as Cora, Citeseer, and Pubmed.

cs.LG↗

arXiv2021

Scalable Multi-Task Gaussian Processes with Neural Embedding of Coregionalization

Multi-task regression attempts to exploit the task similarity in order to achieve knowledge transfer across related tasks for performance improvement. The application of Gaussian process (GP) in this scenario yields the non-parametric yet informative Bayesian multi-task regression paradigm. Multi-task GP (MTGP) provides not only the prediction mean but also the associated prediction variance to quantify uncertainty, thus gaining popularity in various scenarios. The linear model of coregionalization (LMC) is a well-known MTGP paradigm which exploits the dependency of tasks through linear combination of several independent and diverse GPs. The LMC however suffers from high model complexity and limited model capability when handling complicated multi-task cases. To this end, we develop the neural embedding of coregionalization that transforms the latent GPs into a high-dimensional latent space to induce rich yet diverse behaviors. Furthermore, we use advanced variational inference as well as sparse approximation to devise a tight and compact evidence lower bound (ELBO) for higher quality of scalable model inference. Extensive numerical experiments have been conducted to verify the higher prediction quality and better generalization of our model, named NSVLMC, on various real-world multi-task datasets and the cross-fluid modeling of unsteady fluidized bed.

stat.ML↗