arXiv subjects

Jiayi Ji

Publications and source records attributed to Jiayi Ji.

94 records · Page 6Linked to original sources

arXiv2021

Estimating heterogeneous survival treatment effect in observational data using machine learning

Methods for estimating heterogeneous treatment effect in observational data have largely focused on continuous or binary outcomes, and have been relatively less vetted with survival outcomes. Using flexible machine learning methods in the counterfactual framework is a promising approach to address challenges due to complex individual characteristics, to which treatments need to be tailored. To evaluate the operating characteristics of recent survival machine learning methods for the estimation of treatment effect heterogeneity and inform better practice, we carry out a comprehensive simulation study presenting a wide range of settings describing confounded heterogeneous survival treatment effects and varying degrees of covariate overlap. Our results suggest that the nonparametric Bayesian Additive Regression Trees within the framework of accelerated failure time model (AFT-BART-NP) consistently yields the best performance, in terms of bias, precision and expected regret. Moreover, the credible interval estimators from AFT-BART-NP provide close to nominal frequentist coverage for the individual survival treatment effect when the covariate overlap is at least moderate. Including a non-parametrically estimated propensity score as an additional fixed covariate in the AFT-BART-NP model formulation can further improve its efficiency and frequentist coverage. Finally, we demonstrate the application of flexible causal machine learning estimators through a comprehensive case study examining the heterogeneous survival effects of two radiotherapy approaches for localized high-risk prostate cancer.

stat.AP↗

arXiv2020

Improving Image Captioning by Leveraging Intra- and Inter-layer Global Representation in Transformer Network

Transformer-based architectures have shown great success in image captioning, where object regions are encoded and then attended into the vectorial representations to guide the caption decoding. However, such vectorial representations only contain region-level information without considering the global information reflecting the entire image, which fails to expand the capability of complex multi-modal reasoning in image captioning. In this paper, we introduce a Global Enhanced Transformer (termed GET) to enable the extraction of a more comprehensive global representation, and then adaptively guide the decoder to generate high-quality captions. In GET, a Global Enhanced Encoder is designed for the embedding of the global feature, and a Global Adaptive Decoder are designed for the guidance of the caption generation. The former models intra- and inter-layer global representation by taking advantage of the proposed Global Enhanced Attention and a layer-wise fusion module. The latter contains a Global Adaptive Controller that can adaptively fuse the global information into the decoder to guide the caption generation. Extensive experiments on MS COCO dataset demonstrate the superiority of our GET over many state-of-the-arts.

cs.CV↗

arXiv2020

Estimation of Causal Effects of Multiple Treatments in Observational Studies with a Binary Outcome

There is a dearth of robust methods to estimate the causal effects of multiple treatments when the outcome is binary. This paper uses two unique sets of simulations to propose and evaluate the use of Bayesian Additive Regression Trees (BART) in such settings. First, we compare BART to several approaches that have been proposed for continuous outcomes, including inverse probability of treatment weighting (IPTW), targeted maximum likelihood estimator (TMLE), vector matching and regression adjustment. Results suggest that under conditions of non-linearity and non-additivity of both the treatment assignment and outcome generating mechanisms, BART, TMLE and IPTW using generalized boosted models (GBM) provide better bias reduction and smaller root mean squared error. BART and TMLE provide more consistent 95 per cent CI coverage and better large-sample convergence property. Second, we supply BART with a strategy to identify a common support region for retaining inferential units and for avoiding extrapolating over areas of the covariate space where common support does not exist. BART retains more inferential units than the generalized propensity score based strategy, and shows lower bias, compared to TMLE or GBM, in a variety of scenarios differing by the degree of covariate overlap. A case study examining the effects of three surgical approaches for non-small cell lung cancer demonstrates the methods.

stat.ME↗

arXiv2019

Semantic-aware Image Deblurring

Image deblurring has achieved exciting progress in recent years. However, traditional methods fail to deblur severely blurred images, where semantic contents appears ambiguously. In this paper, we conduct image deblurring guided by the semantic contents inferred from image captioning. Specially, we propose a novel Structured-Spatial Semantic Embedding model for image deblurring (termed S3E-Deblur), which introduces a novel Structured-Spatial Semantic tree model (S3-tree) to bridge two basic tasks in computer vision: image deblurring (ImD) and image captioning (ImC). In particular, S3-tree captures and represents the semantic contents in structured spatial features in ImC, and then embeds the spatial features of the tree nodes into GAN based ImD. Co-training on S3-tree, ImC, and ImD is conducted to optimize the overall model in a multi-task end-to-end manner. Extensive experiments on severely blurred MSCOCO and GoPro datasets demonstrate the significant superiority of S3E-Deblur compared to the state-of-the-arts on both ImD and ImC tasks.

cs.CV↗