arXiv subjects

Jiayi Zhong

Publications and source records attributed to Jiayi Zhong.

3 recordsLinked to original sources

arXiv2026

A Safeguarded Projected-Gradient Framework for Complementarity Constrained Least Squares Problems

Both generalized absolute value equations (GAVEs) and linear complementarity problems (LCPs) can be formulated as least-squares problems over the complementarity set. Because this feasible set is nonconvex, projected stationarity does not in general imply zero residual. We develop a safeguarded projected-gradient framework with a linear-system refinement on a selected polyhedral face. We establish matrix conditions under which every projected stationary point is a global solution and derive corresponding global convergence results. Specifically, when refinement on a correct active face returns a solution, we give explicit iteration bounds for active-face identification and prove finite termination. Numerical experiments on GAVE and LCP benchmarks demonstrate the high accuracy of the proposed framework across the tested settings.

math.OC↗

arXiv2026

AI-driven Large-scale Electron Microscopy enables Whole-tissue Subcellular Digitization

The distribution and interactions of cellular organelles play a critical role in mediating cellular physiology and pathology. Large-scale electron microscopy enables visualization of organelle distribution and interactions at the tissue level with nanometer resolution, but robust and efficient computational analysis tools are lacking. Here, we present a deep learning tool for universal large-scale 2D/3D electron microscopy analysis, DeepOrganelle. This new tool enables high-throughput, cell-resolved spatiotemporal mapping and digitization of organelle distribution and interactions. When applied to spermatogenesis across 12 stages and 22 differentiation status of the germ cells, DeepOrganelle uncovered previously unrecognized, stage-dependent dynamics of mitochondria-endoplasmic reticulum contact sites within one subphase of prophase I during meiosis. It also revealed coordinated organelle redistribution in Sertoli cells towards the blood-testis barrier, digitizing the remodeling dynamics of the tissue. This study demonstrates that DeepOrganelle provides a powerful framework that captures subcellular dynamics at the whole-tissue level.

physics.bio-ph↗

arXiv2025

Cycle-Aware ZZ Crosstalk Mitigation on Quantum Hardware

ZZ crosstalk and decoherence hinder superconducting quantum computing. To enhance parallelism in mitigating ZZ crosstalk, we formulate the problem by integrating quantum cycles and two forms of qubit interference. We then propose CYCO, a CYcle-aware ZZ Crosstalk Optimization algorithm, which uses a timing-based greedy strategy to schedule gates through cycles within quantum circuits. A novel data structure called Time and Distance Dependency Graph is designed to model gate data dependencies and physical distances from quantum topologies for precise scheduling. Additionally, dynamically punching barriers reduces idle time in quantum circuits, further enhancing parallelism. Simulations show a reduction of up to 37.44% in quantum program cycle (14.19% on average) on various NISQ devices with 53 to 127 qubits. Real-device experiments on IBMQ-Brisbane demonstrate significant acceleration in quantum computing while maintaining fidelity.

quant-ph↗