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Jiazheng Wang

Publications and source records attributed to Jiazheng Wang.

30 records · Page 2Linked to original sources

EndoChat: Grounded Multimodal Large Language Model for Endoscopic Surgery

Recently, Multimodal Large Language Models (MLLMs) have demonstrated their immense potential in computer-aided diagnosis and decision-making. In the context of robotic-assisted surgery, MLLMs can serve as effective tools for surgical training and guidance. However, there is still a lack of MLLMs specialized for surgical scene understanding in clinical applications. In this work, we introduce EndoChat to address various dialogue paradigms and subtasks in surgical scene understanding that surgeons encounter. To train our EndoChat, we construct the Surg-396K dataset through a novel pipeline that systematically extracts surgical information and generates structured annotations based on collected large-scale endoscopic surgery datasets. Furthermore, we introduce a multi-scale visual token interaction mechanism and a visual contrast-based reasoning mechanism to enhance the model's representation learning and reasoning capabilities. Our model achieves state-of-the-art performance across five dialogue paradigms and eight surgical scene understanding tasks. Additionally, we conduct evaluations with professional surgeons, most of whom provide positive feedback on collaborating with EndoChat. Overall, these results demonstrate that our EndoChat has great potential to significantly advance training and automation in robotic-assisted surgery.

cs.CV↗

Reproducibility Assessment of Magnetic Resonance Spectroscopy of Pregenual Anterior Cingulate Cortex across Sessions and Vendors via the Cloud Computing Platform CloudBrain-MRS

Given the need to elucidate the mechanisms underlying illnesses and their treatment, as well as the lack of harmonization of acquisition and post-processing protocols among different magnetic resonance system vendors, this work is to determine if metabolite concentrations obtained from different sessions, machine models and even different vendors of 3 T scanners can be highly reproducible and be pooled for diagnostic analysis, which is very valuable for the research of rare diseases. Participants underwent magnetic resonance imaging (MRI) scanning once on two separate days within one week (one session per day, each session including two proton magnetic resonance spectroscopy (1H-MRS) scans with no more than a 5-minute interval between scans (no off-bed activity)) on each machine. were analyzed for reliability of within- and between- sessions using the coefficient of variation (CV) and intraclass correlation coefficient (ICC), and for reproducibility of across the machines using correlation coefficient. As for within- and between- session, all CV values for a group of all the first or second scans of a session, or for a session were almost below 20%, and most of the ICCs for metabolites range from moderate (0.4-0.59) to excellent (0.75-1), indicating high data reliability. When it comes to the reproducibility across the three scanners, all Pearson correlation coefficients across the three machines approached 1 with most around 0.9, and majority demonstrated statistical significance (P<0.01). Additionally, the intra-vendor reproducibility was greater than the inter-vendor ones.

stat.ML↗

Unsupervised Multimodal 3D Medical Image Registration with Multilevel Correlation Balanced Optimization

Surgical navigation based on multimodal image registration has played a significant role in providing intraoperative guidance to surgeons by showing the relative position of the target area to critical anatomical structures during surgery. However, due to the differences between multimodal images and intraoperative image deformation caused by tissue displacement and removal during surgery, effective registration of preoperative and intraoperative multimodal images faces significant challenges. To address the multimodal image registration challenges in Learn2Reg 2024, an unsupervised multimodal medical image registration method based on multilevel correlation balanced optimization (MCBO) is designed to solve these problems. First, the features of each modality are extracted based on the modality independent neighborhood descriptor, and the multimodal images are mapped to the feature space. Second, a multilevel pyramidal fusion optimization mechanism is designed to achieve global optimization and local detail complementation of the deformation field through dense correlation analysis and weight-balanced coupled convex optimization for input features at different scales. For preoperative medical images in different modalities, the alignment and stacking of valid information between different modalities is achieved by the maximum fusion between deformation fields. Our method focuses on the ReMIND2Reg task in Learn2Reg 2024, and to verify the generality of the method, we also tested it on the COMULIS3DCLEM task. Based on the results, our method achieved second place in the validation of both two tasks. The code is available at https://github.com/wjiazheng/MCBO.

cs.CV↗

Large Scale Unsupervised Brain MRI Image Registration Solution for Learn2Reg 2024

In this paper, we summarize the methods and experimental results we proposed for Task 2 in the learn2reg 2024 Challenge. This task focuses on unsupervised registration of anatomical structures in brain MRI images between different patients. The difficulty lies in: (1) without segmentation labels, and (2) a large amount of data. To address these challenges, we built an efficient backbone network and explored several schemes to further enhance registration accuracy. Under the guidance of the NCC loss function and smoothness regularization loss function, we obtained a smooth and reasonable deformation field. According to the leaderboard, our method achieved a Dice coefficient of 77.34%, which is 1.4% higher than the TransMorph. Overall, we won second place on the leaderboard for Task 2.

cs.CV↗

One for Multiple: Physics-informed Synthetic Data Boosts Generalizable Deep Learning for Fast MRI Reconstruction

Magnetic resonance imaging (MRI) is a widely used radiological modality renowned for its radiation-free, comprehensive insights into the human body, facilitating medical diagnoses. However, the drawback of prolonged scan times hinders its accessibility. The k-space undersampling offers a solution, yet the resultant artifacts necessitate meticulous removal during image reconstruction. Although Deep Learning (DL) has proven effective for fast MRI image reconstruction, its broader applicability across various imaging scenarios has been constrained. Challenges include the high cost and privacy restrictions associated with acquiring large-scale, diverse training data, coupled with the inherent difficulty of addressing mismatches between training and target data in existing DL methodologies. Here, we present a novel Physics-Informed Synthetic data learning framework for Fast MRI, called PISF. PISF marks a breakthrough by enabling generalized DL for multi-scenario MRI reconstruction through a single trained model. Our approach separates the reconstruction of a 2D image into many 1D basic problems, commencing with 1D data synthesis to facilitate generalization. We demonstrate that training DL models on synthetic data, coupled with enhanced learning techniques, yields in vivo MRI reconstructions comparable to or surpassing those of models trained on matched realistic datasets, reducing the reliance on real-world MRI data by up to 96%. Additionally, PISF exhibits remarkable generalizability across multiple vendors and imaging centers. Its adaptability to diverse patient populations has been validated through evaluations by ten experienced medical professionals. PISF presents a feasible and cost-effective way to significantly boost the widespread adoption of DL in various fast MRI applications.

eess.IV↗

CNTLS: A Benchmark Dataset for Abstractive or Extractive Chinese Timeline Summarization

Timeline summarization (TLS) involves creating summaries of long-running events using dated summaries from numerous news articles. However, limited data availability has significantly slowed down the development of timeline summarization. In this paper, we introduce the CNTLS dataset, a versatile resource for Chinese timeline summarization. CNTLS encompasses 77 real-life topics, each with 2524 documents and summarizes nearly 60\% days duration compression on average all topics. We meticulously analyze the corpus using well-known metrics, focusing on the style of the summaries and the complexity of the summarization task. Specifically, we evaluate the performance of various extractive and generative summarization systems on the CNTLS corpus to provide benchmarks and support further research. To the best of our knowledge, CNTLS is the first Chinese timeline summarization dataset. The dataset and source code are released\footnote{Code and data available at: \emph{\url{https://github.com/OpenSUM/CNTLS}}.}.

cs.AI↗

Magnetic Resonance Spectroscopy Quantification Aided by Deep Estimations of Imperfection Factors and Macromolecular Signal

Objective: Magnetic Resonance Spectroscopy (MRS) is an important technique for biomedical detection. However, it is challenging to accurately quantify metabolites with proton MRS due to serious overlaps of metabolite signals, imperfections because of non-ideal acquisition conditions, and interference with strong background signals mainly from macromolecules. The most popular method, LCModel, adopts complicated non-linear least square to quantify metabolites and addresses these problems by designing empirical priors such as basis-sets, imperfection factors. However, when the signal-to-noise ratio of MRS signal is low, the solution may have large deviation. Methods: Linear Least Squares (LLS) is integrated with deep learning to reduce the complexity of solving this overall quantification. First, a neural network is designed to explicitly predict the imperfection factors and the overall signal from macromolecules. Then, metabolite quantification is solved analytically with the introduced LLS. In our Quantification Network (QNet), LLS takes part in the backpropagation of network training, which allows the feedback of the quantification error into metabolite spectrum estimation. This scheme greatly improves the generalization to metabolite concentrations unseen for training compared to the end-to-end deep learning method. Results: Experiments show that compared with LCModel, the proposed QNet, has smaller quantification errors for simulated data, and presents more stable quantification for 20 healthy in vivo data at a wide range of signal-to-noise ratio. QNet also outperforms other end-to-end deep learning methods. Conclusion: This study provides an intelligent, reliable and robust MRS quantification. Significance: QNet is the first LLS quantification aided by deep learning.

physics.med-ph↗

Magnetic Resonance Spectroscopy Deep Learning Denoising Using Few In Vivo Data

Magnetic Resonance Spectroscopy (MRS) is a noninvasive tool to reveal metabolic information. One challenge of 1H-MRS is the low Signal-Noise Ratio (SNR). To improve the SNR, a typical approach is to perform Signal Averaging (SA) with M repeated samples. The data acquisition time, however, is increased by M times accordingly, and a complete clinical MRS scan takes approximately 10 minutes at a common setting M=128. Recently, deep learning has been introduced to improve the SNR but most of them use the simulated data as the training set. This may hinder the MRS applications since some potential differences, such as acquisition system imperfections, and physiological and psychologic conditions may exist between the simulated and in vivo data. Here, we proposed a new scheme that purely used the repeated samples of realistic data. A deep learning model, Refusion Long Short-Term Memory (ReLSTM), was designed to learn the mapping from the low SNR time-domain data (24 SA) to the high SNR one (128 SA). Experiments on the in vivo brain spectra of 7 healthy subjects, 2 brain tumor patients and 1 cerebral infarction patient showed that only using 20% repeated samples, the denoised spectra by ReLSTM could provide comparable estimated concentrations of metabolites to 128 SA. Compared with the state-of-the-art low-rank denoising method, the ReLSTM achieved the lower relative error and the Cramér-Rao lower bounds in quantifying some important biomarkers. In summary, ReLSTM can perform high-fidelity denoising of the spectra under fast acquisition (24 SA), which would be valuable to MRS clinical studies.

physics.med-ph↗

Improving Primal Heuristics for Mixed Integer Programming Problems based on Problem Reduction: A Learning-based Approach

In this paper, we propose a Bi-layer Predictionbased Reduction Branch (BP-RB) framework to speed up the process of finding a high-quality feasible solution for Mixed Integer Programming (MIP) problems. A graph convolutional network (GCN) is employed to predict binary variables' values. After that, a subset of binary variables is fixed to the predicted value by a greedy method conditioned on the predicted probabilities. By exploring the logical consequences, a learning-based problem reduction method is proposed, significantly reducing the variable and constraint sizes. With the reductive sub-MIP problem, the second layer GCN framework is employed to update the prediction for the remaining binary variables' values and to determine the selection of variables which are then used for branching to generate the Branch and Bound (B&B) tree. Numerical examples show that our BP-RB framework speeds up the primal heuristic and finds the feasible solution with high quality.

math.OC↗

Simplex Initialization: A Survey of Techniques and Trends

The simplex method is one of the most fundamental technologies for solving linear programming (LP) problems and has been widely applied to different practical applications. In the past literature, how to improve and accelerate the simplex method has attracted plenty of research. One important way to achieve this goal is to find a better initialization method for the simplex. In this survey, we aim to provide an overview about the initialization methods in the primal and dual simplex, respectively. We also propose several potential future directions about how to improve the existing initialization methods with the help of advanced learning technologies.

math.OC↗

Branch and Bound in Mixed Integer Linear Programming Problems: A Survey of Techniques and Trends

In this paper, we surveyed the existing literature studying different approaches and algorithms for the four critical components in the general branch and bound (B&B) algorithm, namely, branching variable selection, node selection, node pruning, and cutting-plane selection. However, the complexity of the B&B algorithm always grows exponentially with respect to the increase of the decision variable dimensions. In order to improve the speed of B&B algorithms, learning techniques have been introduced in this algorithm recently. We further surveyed how machine learning can be used to improve the four critical components in B&B algorithms. In general, a supervised learning method helps to generate a policy that mimics an expert but significantly improves the speed. An unsupervised learning method helps choose different methods based on the features. In addition, models trained with reinforcement learning can beat the expert policy, given enough training and a supervised initialization. Detailed comparisons between different algorithms have been summarized in our survey. Finally, we discussed some future research directions to accelerate and improve the algorithms further in the literature.

cs.LG↗

Stochastic Event-based Sensor Schedules for Remote State Estimation in Cognitive Radio Sensor Networks

We consider the problem of communication allocation for remote state estimation in a cognitive radio sensor network~(CRSN). A sensor collects measurements of a physical plant, and transmits the data to a remote estimator as a secondary user (SU) in the shared network. The existence of the primal users (PUs) brings exogenous uncertainties into the transmission scheduling process, and how to design an event-based scheduling scheme considering these uncertainties has not been addressed in the literature. In this work, we start from the formulation of a discrete-time remote estimation process in the CRSN, and then analyze the hidden information contained in the absence of data transmission. In order to achieve a better tradeoff between estimation performance and communication consumption, we propose both open-loop and closed-loop schedules using the hidden information under a Bayesian setting. The open-loop schedule does not rely on any feedback signal but only works for stable plants. For unstable plants, a closed-loop schedule is designed based on feedback signals. The parameter design problems in both schedules are efficiently solved by convex programming. Numerical simulations are included to illustrate the theoretical results.

eess.SY↗