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Jin Keun Seo

Publications and source records attributed to Jin Keun Seo.

31 records · Page 2Linked to original sources

CT sinogram-consistency learning for metal-induced beam hardening correction

This paper proposes a sinogram consistency learning method to deal with beam-hardening related artifacts in polychromatic computerized tomography (CT). The presence of highly attenuating materials in the scan field causes an inconsistent sinogram, that does not match the range space of the Radon transform. When the mismatched data are entered into the range space during CT reconstruction, streaking and shading artifacts are generated owing to the inherent nature of the inverse Radon transform. The proposed learning method aims to repair inconsistent sinograms by removing the primary metal-induced beam-hardening factors along the metal trace in the sinogram. Taking account of the fundamental difficulty in obtaining sufficient training data in a medical environment, the learning method is designed to use simulated training data and a patient-type specific learning model is used to simplify the learning process. The feasibility of the proposed method is investigated using a dataset, consisting of real CT scan of pelvises containing hip prostheses. The anatomical areas in training and test data are different, in order to demonstrate that the proposed method extracts the beam hardening features, selectively. The results show that our method successfully corrects sinogram inconsistency by extracting beam-hardening sources by means of deep learning. This paper proposed a deep learning method of sinogram correction for beam hardening reduction in CT for the first time. Conventional methods for beam hardening reduction are based on regularizations, and have the fundamental drawback of being not easily able to use manifold CT images, while a deep learning approach has the potential to do so.

physics.med-ph↗

Automatic Estimation of Fetal Abdominal Circumference from Ultrasound Images

Ultrasound diagnosis is routinely used in obstetrics and gynecology for fetal biometry, and owing to its time-consuming process, there has been a great demand for automatic estimation. However, the automated analysis of ultrasound images is complicated because they are patient-specific, operator-dependent, and machine-specific. Among various types of fetal biometry, the accurate estimation of abdominal circumference (AC) is especially difficult to perform automatically because the abdomen has low contrast against surroundings, non-uniform contrast, and irregular shape compared to other parameters.We propose a method for the automatic estimation of the fetal AC from 2D ultrasound data through a specially designed convolutional neural network (CNN), which takes account of doctors' decision process, anatomical structure, and the characteristics of the ultrasound image. The proposed method uses CNN to classify ultrasound images (stomach bubble, amniotic fluid, and umbilical vein) and Hough transformation for measuring AC. We test the proposed method using clinical ultrasound data acquired from 56 pregnant women. Experimental results show that, with relatively small training samples, the proposed CNN provides sufficient classification results for AC estimation through the Hough transformation. The proposed method automatically estimates AC from ultrasound images. The method is quantitatively evaluated, and shows stable performance in most cases and even for ultrasound images deteriorated by shadowing artifacts. As a result of experiments for our acceptance check, the accuracies are 0.809 and 0.771 with the expert 1 and expert 2, respectively, while the accuracy between the two experts is 0.905. However, for cases of oversized fetus, when the amniotic fluid is not observed or the abdominal area is distorted, it could not correctly estimate AC.

cs.CV↗

Machine-learning-based nonlinear decomposition of CT images for metal artifact reduction

Computed tomography (CT) images containing metallic objects commonly show severe streaking and shadow artifacts. Metal artifacts are caused by nonlinear beam-hardening effects combined with other factors such as scatter and Poisson noise. In this paper, we propose an implant-specific method that extracts beam-hardening artifacts from CT images without affecting the background image. We found that in cases where metal is inserted in the water (or tissue), the generated beam-hardening artifacts can be approximately extracted by subtracting artifacts generated exclusively by metals. We used a deep learning technique to train nonlinear representations of beam-hardening artifacts arising from metals, which appear as shadows and streaking artifacts. The proposed network is not designed to identify ground-truth CT images (i.e., the CT image before its corruption by metal artifacts). Consequently, these images are not required for training. The proposed method was tested on a dataset consisting of real CT scans of pelvises containing simulated hip prostheses. The results demonstrate that the proposed deep learning method successfully extracts both shadowing and streaking artifacts.

physics.med-ph↗

A Fidelity-embedded Regularization Method for Robust Electrical Impedance Tomography

Electrical impedance tomography (EIT) provides functional images of an electrical conductivity distribution inside the human body. Since the 1980s, many potential clinical applications have arisen using inexpensive portable EIT devices. EIT acquires multiple trans-impedance measurements across the body from an array of surface electrodes around a chosen imaging slice. The conductivity image reconstruction from the measured data is a fundamentally ill-posed inverse problem notoriously vulnerable to measurement noise and artifacts. Most available methods invert the ill-conditioned sensitivity or Jacobian matrix using a regularized least-squares data-fitting technique. Their performances rely on the regularization parameter, which controls the trade-off between fidelity and robustness. For clinical applications of EIT, it would be desirable to develop a method achieving consistent performance over various uncertain data, regardless of the choice of the regularization parameter. Based on the analysis of the structure of the Jacobian matrix, we propose a fidelity-embedded regularization (FER) method and a motion artifact removal filter. Incorporating the Jacobian matrix in the regularization process, the new FER method with the motion artifact removal filter offers stable reconstructions of high-fidelity images from noisy data by taking a very large regularization parameter value. The proposed method showed practical merits in experimental studies of chest EIT imaging.

math.AP↗

Dipole Incompatibility Related Artifacts in Quantitative Susceptibility Mapping

Artifacts in quantitative susceptibility mapping (QSM) are analyzed to establish an optimal design criterion for QSM inversion algorithms. The magnetic field data is decomposed into two parts, dipole compatible and incompatible parts. The dipole compatible part generates the desired non-streaking solution. The dipole incompatible part, including noise, discretization error, and anisotropy sources, generates artifacts defined by a wave propagator with the B0 field direction as the time axis. Granular noise causes streaking and contiguous error causes both streaking and shadow artifacts. As an example, truncation-based QSM algorithms are inherently prone to streaking artifacts because of the deviation of the dipole kernel during truncation. Through numerical phantom and imaging experiments, several QSM methods, including a Bayesian regularization method and the k-space truncation methods, were compared to show that the Bayesian approach with a structural prior provides advantages in terms of both image quality and quantitative measures.

physics.med-ph↗

Mathematical framework for abdominal electrical impedance tomography to assess fatness

This paper presents a static electrical impedance tomography (EIT) technique that evaluates abdominal obesity by estimating the thickness of subcutaneous fat. EIT has a fundamental drawback for absolute admittivity imaging because of its lack of reference data for handling the forward modeling errors. To reduce the effect of boundary geometry errors in imaging abdominal fat, we develop a depth-based reconstruction method that uses a specially chosen current pattern to construct reference-like data, which are then used to identify the border between subcutaneous fat and muscle. The performance of the proposed method is demonstrated by numerical simulations using 32-channel EIT system and human like domain.

math.NA↗

Mathematical framework for multi-frequency identification of thin insulating and small conductive inhomogeneities

We are aiming to identify the thin insulating inhomogeneities and small conductive inhomogeneities inside an electrically conducting medium by using multi-frequency electrical impedance tomography (mfEIT). The thin insulating inhomogeneities are considered in the form of tubular neighborhood of a curve and small conductive inhomogeneities are regarded as circular disks. Taking advantage of the frequency dependent behavior of insulating objects, we give a rigorous derivation of the potential along thin insulating objects at various frequencies. Asymptotic formula is given to analyze relationship between inhomogeneities and boundary potential at different frequencies. In numerical simulations, spectroscopic images are provided to visualize the reconstructed admittivity at various frequencies. For the view of both kinds of inhomogeneities, an integrated reconstructed image based on principle component analysis (PCA) is provided. Phantom experiments are performed by using Swisstom EIT-Pioneer Set.

math.AP↗

Magnetic resonance-based reconstruction method of conductivity and permittivity distributions at the Larmor frequency

Magnetic resonance electrical property tomography is a recent medical imaging modality for visualizing the electrical tissue properties of the human body using radio-frequency magnetic fields. It uses the fact that in magnetic resonance imaging systems the eddy currents induced by the radio-frequency magnetic fields reflect the conductivity ($σ$) and permittivity ($ε$) distributions inside the tissues through Maxwell's equations. The corresponding inverse problem consists of reconstructing the admittivity distribution ($γ=σ+iωε$) at the Larmor frequency ($ω/2π=$128 MHz for a 3 tesla MRI machine) from the positive circularly polarized component of the magnetic field ${\bf H}=(H_x,H_y,H_z)$. Previous methods are usually based on an assumption of local homogeneity ($\nablaγ\approx 0$) which simplifies the governing equation. However, previous methods that include the assumption of homogeneity are prone to artifacts in the region where $γ$ varies. Hence, recent work has sought a reconstruction method that does not assume local-homogeneity. This paper presents a new magnetic resonance electrical property tomography reconstruction method which does not require any local homogeneity assumption on $γ$. We find that $γ$ is a solution of a semi-elliptic partial differential equation with its coefficients depending only on the measured data $H^+$, which enable us to compute a blurred version of $γ$. To improve the resolution of the reconstructed image, we developed a new optimization algorithm that minimizes the mismatch between the data and the model data as a highly nonlinear function of $γ$. Numerical simulations are presented to illustrate the potential of the proposed reconstruction method.

math.AP↗

Electrical impedance tomography-based pressure-sensing using conductive membrane

This paper presents a mathematical framework for a flexible pressure-sensor model using electrical impedance tomography (EIT). When pressure is applied to a conductive membrane patch with clamped boundary, the pressure-induced surface deformation results in a change in the conductivity distribution. This change can be detected in the current-voltage data ({\it i.e.,} EIT data) measured on the boundary of the membrane patch. Hence, the corresponding inverse problem is to reconstruct the pressure distribution from the data. The 2D apparent conductivity (in terms of EIT data) corresponding to the surface deformation is anisotropic. Thus, we consider a constrained inverse problem by restricting the coefficient tensor to the range of the map from pressure to 2D-apparent conductivity. This paper provides theoretical grounds for the mathematical model of the inverse problem. We develop a reconstruction algorithm based on a careful sensitivity analysis. We demonstrate the performance of the reconstruction algorithm through numerical simulations to validate its feasibility for future experimental studies.

math.AP↗

Viscoelastic modulus reconstruction using time harmonic vibrations

This paper presents a new iterative reconstruction method to provide high-resolution images of shear modulus and viscosity via the internal measurement of displacement fields in tissues. To solve the inverse problem, we compute the Fréchet derivatives of the least-squares discrepancy functional with respect to the shear modulus and shear viscosity. The proposed iterative reconstruction method using this Fréchet derivative does not require any differentiation of the displacement data for the full isotropic linearly viscoelastic model, whereas the standard reconstruction methods require at least double differentiation. Because the minimization problem is ill-posed and highly nonlinear, this adjoint-based optimization method needs a very well-matched initial guess. We find a good initial guess. For a well-matched initial guess, numerical experiments show that the proposed method considerably improves the quality of the reconstructed viscoelastic images.

math.AP↗

Characterization of Metal Artifacts in X-ray Computed Tomography

Metal streak artifacts in X-ray computerized tomography (CT) are rigorously characterized here using the notion of the wavefront set from microlocal analysis. The metal artifacts are caused mainly from the mismatch of the forward model of the filtered back-projection; the presence of metallic subjects in an imaging subject violates the model's assumption of the CT sinogram data being the Radon transform of an image. The increasing use of metallic implants has increased demand for the reduction of metal artifacts in the field of dental and medical radiography. However, it is a challenging issue due to the serious difficulties in analyzing the X-ray data, which depends nonlinearly on the distribution of the metallic subject. In this paper, we found that the metal streaking artifacts cause mainly from the boundary geometry of the metal region. The metal streaking artifacts are produced only when the wavefront set of the Radon transform of the characteristic function of a metal region does not contain the wavefront set of the square of the Radon transform. We also found a sufficient condition for the non-existence of the metal streak artifacts.

math.AP↗

Electrical impedance spectroscopy-based nondestructive testing for imaging defects in concrete structures

An electrical impedance spectroscopy-based nondestructive testing (NDT) method is proposed to image both cracks and reinforcing bars in concrete structures. The method utilizes the frequency-dependent behavior of thin insulating cracks: low-frequency electrical currents are blocked by insulating cracks, whereas high-frequency currents can pass through the conducting bars without being blocked by thin cracks. Rigorous mathematical analysis relates the geometric structures of the cracks and bars to the frequency-dependent Neumann-to-Dirichlet data. Various numerical simulations support the feasibility of the proposed method.

math.AP↗

Mathematical modeling of mechanical vibration assisted conductivity imaging

This paper aims at mathematically modeling a new multi-physics conductivity imaging system incorporating mechanical vibrations simultaneously applied to an imaging object together with current injections. We perturb the internal conductivity distribution by applying time-harmonic mechanical vibrations on the boundary. This enhances the effects of any conductivity discontinuity on the induced internal current density distribution. Unlike other conductivity contrast enhancing frameworks, it does not require a prior knowledge of a reference data. In this paper, we provide a mathematical framework for this novel imaging modality. As an application of the vibration-assisted impedance imaging framework, we propose a new breast image reconstruction method in electrical impedance tomography (EIT). As its another application, we investigate a conductivity anomaly detection problem and provide an efficient location search algorithm. We show both analytically and numerically that the applied mechanical vibration increases the data sensitivity to the conductivity contrast and enhances the quality of reconstructed images and anomaly detection results. For numerous applications in impedance imaging, the proposed multi-physics method opens a new difference imaging area called the vibration-difference imaging, which can augment the time-difference and also frequency-difference imaging methods for sensitivity improvements.

physics.med-ph↗