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Jin Liu

Publications and source records attributed to Jin Liu.

At least 73 records · Page 4Linked to original sources

UniTac2Pose: A Unified Approach Learned in Simulation for Category-level Visuotactile In-hand Pose Estimation

Accurate estimation of the in-hand pose of an object based on its CAD model is crucial in both industrial applications and everyday tasks, ranging from positioning workpieces and assembling components to seamlessly inserting devices like USB connectors. While existing methods often rely on regression, feature matching, or registration techniques, achieving high precision and generalizability to unseen CAD models remains a significant challenge. In this paper, we propose a novel three-stage framework for in-hand pose estimation. The first stage involves sampling and pre-ranking pose candidates, followed by iterative refinement of these candidates in the second stage. In the final stage, post-ranking is applied to identify the most likely pose candidates. These stages are governed by a unified energy-based diffusion model, which is trained solely on simulated data. This energy model simultaneously generates gradients to refine pose estimates and produces an energy scalar that quantifies the quality of the pose estimates. Additionally, borrowing the idea from the computer vision domain, we incorporate a render-compare architecture within the energy-based score network to significantly enhance sim-to-real performance, as demonstrated by our ablation studies. We conduct comprehensive experiments to show that our method outperforms conventional baselines based on regression, matching, and registration techniques, while also exhibiting strong intra-category generalization to previously unseen CAD models. Moreover, our approach integrates tactile object pose estimation, pose tracking, and uncertainty estimation into a unified framework, enabling robust performance across a variety of real-world conditions.

cs.LG↗

HypoGeneAgent: A Hypothesis Language Agent for Gene-Set Cluster Resolution Selection Using Perturb-seq Datasets

Large-scale single-cell and Perturb-seq investigations routinely involve clustering cells and subsequently annotating each cluster with Gene-Ontology (GO) terms to elucidate the underlying biological programs. However, both stages, resolution selection and functional annotation, are inherently subjective, relying on heuristics and expert curation. We present HYPOGENEAGENT, a large language model (LLM)-driven framework, transforming cluster annotation into a quantitatively optimizable task. Initially, an LLM functioning as a gene-set analyst analyzes the content of each gene program or perturbation module and generates a ranked list of GO-based hypotheses, accompanied by calibrated confidence scores. Subsequently, we embed every predicted description with a sentence-embedding model, compute pair-wise cosine similarities, and let the agent referee panel score (i) the internal consistency of the predictions, high average similarity within the same cluster, termed intra-cluster agreement (ii) their external distinctiveness, low similarity between clusters, termed inter-cluster separation. These two quantities are combined to produce an agent-derived resolution score, which is maximized when clusters exhibit simultaneous coherence and mutual exclusivity. When applied to a public K562 CRISPRi Perturb-seq dataset as a preliminary test, our Resolution Score selects clustering granularities that exhibit alignment with known pathway compared to classical metrics such silhouette score, modularity score for gene functional enrichment summary. These findings establish LLM agents as objective adjudicators of cluster resolution and functional annotation, thereby paving the way for fully automated, context-aware interpretation pipelines in single-cell multi-omics studies.

q-bio.QM↗

Anderson Delocalization in Strongly Coupled Disordered Non-Hermitian Chains

Disorder and non-Hermitian effects together can upend how waves localize. In a 1D disordered chain, the non-Hermitian skin effect (NHSE) can induce Anderson delocalization, defying the usual rule that disorder in low dimensions always localizes states. While weak disorder leaves the NHSE intact, strong disorder restores Anderson localization. Here, we study a surprising twist: coupling a strongly disordered Hatano-Nelson chain to a disordered Hermitian chain with their disorder anti-symmetrically correlated. Strikingly, once the inter-chain coupling exceeds a threshold, the system undergoes Anderson delocalization irrespective of disorder strength, reinstating the NHSE with no Hermitian counterpart. This transition arises from the interplay of non-reciprocal hopping, inter-chain coupling, and engineered disorder correlations, and is captured by a real-space winding number. To confirm this, we build an electrical-circuit analog and directly observe the re-emergent NHSE via voltage measurements. Our work uncovers unexplored and experimentally accessible physics at the crossroads of non-Hermiticity and disorder.

cond-mat.dis-nn↗

FedSWA: Improving Generalization in Federated Learning with Highly Heterogeneous Data via Momentum-Based Stochastic Controlled Weight Averaging

For federated learning (FL) algorithms such as FedSAM, their generalization capability is crucial for real-word applications. In this paper, we revisit the generalization problem in FL and investigate the impact of data heterogeneity on FL generalization. We find that FedSAM usually performs worse than FedAvg in the case of highly heterogeneous data, and thus propose a novel and effective federated learning algorithm with Stochastic Weight Averaging (called \texttt{FedSWA}), which aims to find flatter minima in the setting of highly heterogeneous data. Moreover, we introduce a new momentum-based stochastic controlled weight averaging FL algorithm (\texttt{FedMoSWA}), which is designed to better align local and global models. Theoretically, we provide both convergence analysis and generalization bounds for \texttt{FedSWA} and \texttt{FedMoSWA}. We also prove that the optimization and generalization errors of \texttt{FedMoSWA} are smaller than those of their counterparts, including FedSAM and its variants. Empirically, experimental results on CIFAR10/100 and Tiny ImageNet demonstrate the superiority of the proposed algorithms compared to their counterparts. Open source code at: https://github.com/junkangLiu0/FedSWA.

cs.LG↗

Bipartite Patient-Modality Graph Learning with Event-Conditional Modelling of Censoring for Cancer Survival Prediction

Accurately predicting the survival of cancer patients is crucial for personalized treatment. However, existing studies focus solely on the relationships between samples with known survival risks, without fully leveraging the value of censored samples. Furthermore, these studies may suffer performance degradation in modality-missing scenarios and even struggle during the inference process. In this study, we propose a bipartite patient-modality graph learning with event-conditional modelling of censoring for cancer survival prediction (CenSurv). Specifically, we first use graph structure to model multimodal data and obtain representation. Then, to alleviate performance degradation in modality-missing scenarios, we design a bipartite graph to simulate the patient-modality relationship in various modality-missing scenarios and leverage a complete-incomplete alignment strategy to explore modality-agnostic features. Finally, we design a plug-and-play event-conditional modeling of censoring (ECMC) that selects reliable censored data using dynamic momentum accumulation confidences, assigns more accurate survival times to these censored data, and incorporates them as uncensored data into training. Comprehensive evaluations on 5 publicly cancer datasets showcase the superiority of CenSurv over the best state-of-the-art by 3.1% in terms of the mean C-index, while also exhibiting excellent robustness under various modality-missing scenarios. In addition, using the plug-and-play ECMC module, the mean C-index of 8 baselines increased by 1.3% across 5 datasets. Code of CenSurv is available at https://github.com/yuehailin/CenSurv.

cs.LG↗

BS-LDM: Effective Bone Suppression in High-Resolution Chest X-Ray Images with Conditional Latent Diffusion Models

Lung diseases represent a significant global health challenge, with Chest X-Ray (CXR) being a key diagnostic tool due to its accessibility and affordability. Nonetheless, the detection of pulmonary lesions is often hindered by overlapping bone structures in CXR images, leading to potential misdiagnoses. To address this issue, we develop an end-to-end framework called BS-LDM, designed to effectively suppress bone in high-resolution CXR images. This framework is based on conditional latent diffusion models and incorporates a multi-level hybrid loss-constrained vector-quantized generative adversarial network which is crafted for perceptual compression, ensuring the preservation of details. To further enhance the framework's performance, we utilize offset noise in the forward process, and a temporal adaptive thresholding strategy in the reverse process. These additions help minimize discrepancies in generating low-frequency information of soft tissue images. Additionally, we have compiled a high-quality bone suppression dataset named SZCH-X-Rays. This dataset includes 818 pairs of high-resolution CXR and soft tissue images collected from our partner hospital. Moreover, we processed 241 data pairs from the JSRT dataset into negative images, which are more commonly used in clinical practice. Our comprehensive experiments and downstream evaluations reveal that BS-LDM excels in bone suppression, underscoring its clinical value. Our code is available at https://github.com/diaoquesang/BS-LDM.

eess.IV↗

Optical trapping based on microring resonators with transverse slot structure

Over the past few decades, optical manipulation has emerged as a highly successful tool in various fields, such as biology, micro/nanorobotics, and physics. Among the different techniques, the transverse slot optical waveguide has shown remarkable potential in enhancing the field and significantly improving optical trapping capabilities. Additionally, microring resonators have demonstrated the ability to enhance the field at specific resonance wavelengths, enabling the manipulation and capture of particles. In this study, we investigated the impact of the structure on nanoparticle capture by introducing a 50 nm transverse slot in a 5 μm microring resonator. Through the integration of a transverse slot in the microring resonator, we observed a substantial increase in the maximum bound optical power for a nanosphere with a refractive index of 1.6 and a diameter of 50 nm, reaching 3988.8 pN/W. This value is 2292 times higher than the maximum optical force in a straight waveguide and 2.266 times higher than the maximum optical force in a microring resonator. The proposed structure significantly enhances the optical trapping capabilities for nanoscale particles, thus paving the way for the development of advanced micro/nanomanipulation techniques.

physics.optics↗

Nonlinearization of the KdV-type and mKdV-type bilinear equations

In this paper, we show a general procedure to nonlinearize bilinear equations by using the Bell polynomials. As applications, we obtain nonlinear forms of some integrable bilinear equations (in the sense having 3-soliton solutions) of the KdV type and mKdV type that were found by Jarmo Hietarinta in 1980s. Examples of non-integrable bilinear equations of the KdV type are also given.

nlin.SI↗

On-chip Non-Hermitian Cavity Quantum Electrodynamics

Exceptional points (EPs) promise revolutionary control over quantum light-matter interactions. Here, we experimentally demonstrate flexible and reversible engineering of quantum vacuum fluctuation in an integrated microcavity supporting chiral Eps. We develop a hybrid lithium niobate (LN)-GaAs quantum photonic platform, seamlessly combining high-quality quantum emitters, a low-loss photonic circuit, efficient electro-optic (EO) effect, and local strain actuator in a single device. Chiral EPs are implemented by dynamically tuning the coupling between the modes associated with a micro-ring resonator, resulting in anomalous spontaneous emission dynamic with a 7-fold modulation of the lifetime (120 ps to 850 ps). Meanwhile, we reshape single-photon spectra via cavity local density of states (LDOS) engineering and generate non-Lorentzian spectral profiles: squared-Lorentzian, Fano-like, and EP-induced transparency (EPIT), a suppression of emission at zero detuning. This work unveils exotic cavity quantum electrodynamics (cQED) effects unique to EPs and establishes a universal paradigm for non-Hermitian quantum photonics.

physics.optics↗

Streamlining Biomedical Research with Specialized LLMs

In this paper, we propose a novel system that integrates state-of-the-art, domain-specific large language models with advanced information retrieval techniques to deliver comprehensive and context-aware responses. Our approach facilitates seamless interaction among diverse components, enabling cross-validation of outputs to produce accurate, high-quality responses enriched with relevant data, images, tables, and other modalities. We demonstrate the system's capability to enhance response precision by leveraging a robust question-answering model, significantly improving the quality of dialogue generation. The system provides an accessible platform for real-time, high-fidelity interactions, allowing users to benefit from efficient human-computer interaction, precise retrieval, and simultaneous access to a wide range of literature and data. This dramatically improves the research efficiency of professionals in the biomedical and pharmaceutical domains and facilitates faster, more informed decision-making throughout the R\&D process. Furthermore, the system proposed in this paper is available at https://synapse-chat.patsnap.com.

cs.CL↗

Embodied Perception for Test-time Grasping Detection Adaptation with Knowledge Infusion

It has always been expected that a robot can be easily deployed to unknown scenarios, accomplishing robotic grasping tasks without human intervention. Nevertheless, existing grasp detection approaches are typically off-body techniques and are realized by training various deep neural networks with extensive annotated data support. {In this paper, we propose an embodied test-time adaptation framework for grasp detection that exploits the robot's exploratory capabilities.} The framework aims to improve the generalization performance of grasping skills for robots in an unforeseen environment. Specifically, we introduce embodied assessment criteria based on the robot's manipulation capability to evaluate the quality of the grasp detection and maintain suitable samples. This process empowers the robots to actively explore the environment and continuously learn grasping skills, eliminating human intervention. Besides, to improve the efficiency of robot exploration, we construct a flexible knowledge base to provide context of initial optimal viewpoints. Conditioned on the maintained samples, the grasp detection networks can be adapted in the test-time scene. When the robot confronts new objects, it will undergo the same adaptation procedure mentioned above to realize continuous learning. Extensive experiments conducted on a real-world robot demonstrate the effectiveness and generalization of our proposed framework.

cs.RO↗

In-situ three-dimensional strain engineering of solid-state quantum emitters in photonic structures towards scalable quantum networks

Solid-state quantum emitters are pivotal for modern photonic quantum technology, yet their inherent spectral inhomogeneity imposes a critical challenge in pursuing scalable quantum network. Here, we develop a cryogenic-compatible strain-engineering platform based on a polydimethylsiloxane (PDMS) stamp that is not obviously working properly at cryogenic temperature. In-situ three-dimensional (3D) strain control is achieved for quantum dots (QDs) embedded in photonic nanostructures. The compliant PDMS enables independent tuning of emission energy and elimination of fine structure splitting (FSS) of single QDs, as demonstrated by a 7 meV spectral shift with a near-vanishing FSS in circular Bragg resonators and an unprecedented 15 meV tuning range in the micropillar. The PDMS-based 3D strain-engineering platform, compatible with diverse photonic structures at cryogenic temperature, provides a powerful and versatile tool for exploring fundamental strain-related physics and advancing integrated photonic quantum technology.

physics.optics↗

WHERE-Bot: a Wheel-less Helical-ring Everting Robot Capable of Omnidirectional Locomotion

Compared to conventional wheeled transportation systems designed for flat surfaces, soft robots exhibit exceptional adaptability to various terrains, enabling stable movement in complex environments. However, due to the risk of collision with obstacles and barriers, most soft robots rely on sensors for navigation in unstructured environments with uncertain boundaries. In this work, we present the WHERE-Bot, a wheel-less everting soft robot capable of omnidirectional locomotion. Our WHERE-Bot can navigate through unstructured environments by leveraging its structural and motion advantages rather than relying on sensors for boundary detection. By configuring a spring toy ``Slinky'' into a loop shape, the WHERE-Bot performs multiple rotational motions: spiral-rotating along the hub circumference, self-rotating around the hub's center, and orbiting around a certain point. The robot's trajectories can be reprogrammed by actively altering its mass distribution. The WHERE-Bot shows significant potential for boundary exploration in unstructured environments.

cs.RO↗

Quantifying patterns of punctuation in modern Chinese prose

Recent research shows that punctuation patterns in texts exhibit universal features across languages. Analysis of Western classical literature reveals that the distribution of spaces between punctuation marks aligns with a discrete Weibull distribution, typically used in survival analysis. By extending this analysis to Chinese literature represented here by three notable contemporary works, it is shown that Zipf's law applies to Chinese texts similarly to Western texts, where punctuation patterns also improve adherence to the law. Additionally, the distance distribution between punctuation marks in Chinese texts follows the Weibull model, though larger spacing is less frequent than in English translations. Sentence-ending punctuation, representing sentence length, diverges more from this pattern, reflecting greater flexibility in sentence length. This variability supports the formation of complex, multifractal sentence structures, particularly evident in Gao Xingjian's "Soul Mountain". These findings demonstrate that both Chinese and Western texts share universal punctuation and word distribution patterns, underscoring their broad applicability across languages.

cs.CL↗

Experimental Observation of Topological Disclination States in Lossy Electric Circuits

Topological phase transitions can be remarkably induced purely by manipulating gain and loss mechanisms, offering a novel approach to engineering topological properties. Recent theoretical studies have revealed gain-loss-induced topological disclination states, along with the associated fractional charge trapped at the disclination sites. Here, we present the experimental demonstration of topological disclination states in a purely lossy electric circuit. By designing alternating lossy electric circuit networks that correspond to the disclination lattice, we observe a voltage response localized at the disclination sites and demonstrate the robustness of these states against disorder. Furthermore, we measure the charge distribution, confirming the presence of fractional charge at the disclination sites, which gives rise to the topological disclination states. Our experiment provides direct evidence of gain-loss-induced topological disclination states in electric circuits, opening new possibilities for applications in classical systems.

cond-mat.mes-hall↗

Multi-modal Multi-kernel Graph Learning for Autism Prediction and Biomarker Discovery

Due to its complexity, graph learning-based multi-modal integration and classification is one of the most challenging obstacles for disease prediction. To effectively offset the negative impact between modalities in the process of multi-modal integration and extract heterogeneous information from graphs, we propose a novel method called MMKGL (Multi-modal Multi-Kernel Graph Learning). For the problem of negative impact between modalities, we propose a multi-modal graph embedding module to construct a multi-modal graph. Different from conventional methods that manually construct static graphs for all modalities, each modality generates a separate graph by adaptive learning, where a function graph and a supervision graph are introduced for optimization during the multi-graph fusion embedding process. We then propose a multi-kernel graph learning module to extract heterogeneous information from the multi-modal graph. The information in the multi-modal graph at different levels is aggregated by convolutional kernels with different receptive field sizes, followed by generating a cross-kernel discovery tensor for disease prediction. Our method is evaluated on the benchmark Autism Brain Imaging Data Exchange (ABIDE) dataset and outperforms the state-of-the-art methods. In addition, discriminative brain regions associated with autism are identified by our model, providing guidance for the study of autism pathology.

cs.LG↗

Pre-train and Fine-tune: Recommenders as Large Models

In reality, users have different interests in different periods, regions, scenes, etc. Such changes in interest are so drastic that they are difficult to be captured by recommenders. Existing multi-domain learning can alleviate this problem. However, the structure of the industrial recommendation system is complex, the amount of data is huge, and the training cost is extremely high, so it is difficult to modify the structure of the industrial recommender and re-train it. To fill this gap, we consider recommenders as large pre-trained models and fine-tune them. We first propose the theory of the information bottleneck for fine-tuning and present an explanation for the fine-tuning technique in recommenders. To tailor for recommendation, we design an information-aware adaptive kernel (IAK) technique to fine-tune the pre-trained recommender. Specifically, we define fine-tuning as two phases: knowledge compression and knowledge matching and let the training stage of IAK explicitly approximate these two phases. Our proposed approach designed from the essence of fine-tuning is well interpretable. Extensive online and offline experiments show the superiority of our proposed method. Besides, we also share unique and important lessons we learned when deploying the method in a large-scale online platform. We also present the potential issues of fine-tuning techniques in recommendation systems and the corresponding solutions. The recommender with IAK technique has been deployed on the homepage of a billion-scale online food platform for several months and has yielded considerable profits in our business.

cs.IR↗

Localization-Delocalization Transitions in Non-Hermitian Aharonov-Bohm Cages

A unique feature of non-Hermitian systems is the extreme sensitivity of the eigenspectrum to boundary conditions with the emergence of the non-Hermitian skin effect (NHSE). A NHSE originates from the point-gap topology of complex eigenspectrum, where an extensive number of eigenstates are anomalously localized at the boundary driven by nonreciprocal dissipation. Two different approaches to create localization are disorder and flat-band spectrum, and their interplay can lead to the anomalous inverse Anderson localization, where the Bernoulli anti-symmetric disorder induce mobility in a full-flat band system in the presence of Aharonov-Bohm (AB) Cage. In this work, we study the localization-delocalization transitions due to the interplay of the point-gap topology, flat band and correlated disorder in the one-dimensional rhombic lattice, where both its Hermitian and non-Hermitian structures show AB cage in the presence of magnetic flux. Although it remains the coexistence of localization and delocalization for the Hermitian rhombic lattice in the presence of the random anti-symmetric disorder, it surprisingly becomes complete delocalization, accompanied by the emergence of NHSE. To further study the effects from the Bernoulli anti-symmetric disorder, we found the similar NHSE due to the interplay of the point-gap topology, correlated disorder and flat bands. Our anomalous localization-delocalization property can be experimentally tested in the classical physical platform, such as electrical circuit.

cond-mat.mes-hall↗