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Jinglun Li

Publications and source records attributed to Jinglun Li.

At least 19 recordsLinked to original sources

EpaCache: Error-Propagation-Aware Caching for Accelerating Diffusion-Based Visual Generation

Diffusion-based visual generative models deliver strong image and video synthesis quality but incur high inference costs because sequential samplers repeatedly evaluate large networks. Caching-based methods reduce inference latency by reusing intermediate computations across adjacent timesteps. However, existing cache controllers rely primarily on local temporal variation and overlook the trajectory-level consequences of cache reuse. We introduce Error-Propagation-Aware Cache (EpaCache), a training-free caching policy that adaptively allocates the reuse budget on timesteps with lower downstream impact. Experiments on image and video synthesis models demonstrate that EpaCache consistently improves the latency--fidelity trade-off over existing caching methods. On FLUX.1-dev, EpaCache outperforms the prior state-of-the-art caching method in both latency and fidelity, reducing inference time from $11.7$ s to $11.3$ s while improving PSNR from $21.4$ to $22.8$. On HunyuanVideo, EpaCache achieves a $2.63\times$ speedup over uncached inference and improves SSIM from $0.891$ to $0.905$ over the prior state-of-the-art method at matched latency.

cs.AI

SPARE: Structural Parameter-Free Affinity Regularization for Flow Matching

Denoising diffusion transformers achieve strong generation quality but converge slowly during training. Regularizing their internal representations has emerged as an effective accelerator, yet existing methods split into two families with complementary costs. Target-based methods strengthen representations by aligning them to external features, which requires an external encoder and a learnable projection head to bridge feature spaces. Target-free methods hold no reference at all, and can only repel the model's own features across samples or layers, discarding whatever structure the data contains. Prior work suggests that spatial structure, rather than global semantics, drives the gains of alignment. We therefore ask whether such structure can serve as a target directly, and whether it exists not only within an image but across images. Our key insight is that the clean data latent already carries this structure in the relations among its tokens, where a relation is the similarity between two tokens, a single scalar comparable across feature spaces without a projection head. We propose Structural Parameter-free Affinity Regularization (SPARE), a regularizer that matches the pairwise affinities of intermediate tokens to those of the clean latents. To exploit this structure fully, SPARE extends the matching to token pairs across images, precisely the pairs that prior target-free methods repel by default, and calibrates both relation types with a single learning objective. On ImageNet $256 \times 256$ with SiT backbones under matched 400K-iteration budgets, SPARE adds no encoder, head, or parameters and only 0.08 GB of training memory, yet attains the lowest FID among parameter-free regularizers in every tested setting, recovers 37 to 54\% of REPA's FID reduction, and improves over REPA when combined with it, reaching FID 1.90 under classifier-free guidance at 1M iterations.

cs.CV

pVACtools v6: A comprehensive suite for neoantigen prediction, visualization, and therapy design

With the rise of checkpoint blockade therapies and neoantigen-based vaccines reaching later-stage trials, there is a growing need for computational tools to identify and prioritize neoantigens. pVACtools, initially introduced in 2016, is an open-source informatic suite designed to support basic and translational neoantigen research. pVACtools assists prediction, prioritization, and visualization of neoantigens, as well as design of neoantigen-based therapies. We describe several major advances to pVACtools since the last update: (1) expanded neoantigen quality and safety assessment features, including support for peptide presentation scoring, immunogenicity prediction, anchor residue analysis, reference proteome similarity, percentile score calculation; (2) addition of pVACsplice, a new tool for predicting neoantigens from tumor-specific cis-splicing mutations; (3) addition of pVACbind, a flexible tool that supports noncanonical neoantigen sources; (4) improvement in neoantigen selection strategies; (5) a substantially improved pVACvector algorithm that achieves higher DNA/mRNA vector vaccine design success rates with shorter runtimes; (6) new utilities to support synthetic long peptide vaccine design; (7) extended prediction support for many non-human species; and (8) addition of pVACcompare, a tool to support comparison between two pVACseq results. Together, these updates reinforce pVACtools as the field's most comprehensive toolkit for neoantigen research, from basic discovery to the design and execution of personalized cancer vaccine clinical trials.

q-bio.QM

The Velocity Deficit: Initial Energy Injection for Flow Matching

While Flow Matching theoretically guarantees constant-velocity trajectories, we identify a critical breakdown in high-dimensional practice: the Velocity Deficit. We show that the MSE objective systematically underestimates velocity magnitude, causing generated samples to fail to reach the data manifold-a phenomenon we term Integration Lag. To rectify this, we propose Initial Energy Injection, instantiated via two complementary methods: the training-based Magnitude-Aware Flow Matching (MAFM) and the training-free Scale Schedule Corrector (SSC). Both are grounded in our discovery of a crucial asymmetry: velocity contraction causes harmful kinetic stagnation at the trajectory's start, yet acts as a beneficial denoising mechanism at its end. Empirically, SSC yields significant efficiency gains with zero retraining and just one line of code. On ImageNet-1k (256x256), it improves FID by 44.6% (from 13.68 to 7.58) and achieves a 5x speedup, enabling a 50-step generator (FID 7.58) to beat a 250-step baseline (FID 8.65). Furthermore, our methods generalize to Text-to-Image tasks and high-resolution generation, improving FID on MS-COCO by ~22%.

cs.CV

Unified Multimodal Visual Tracking with Dual Mixture-of-Experts

Multimodal visual object tracking can be divided into to several kinds of tasks (e.g. RGB and RGB+X tracking), based on the input modality. Existing methods often train separate models for each modality or rely on pretrained models to adapt to new modalities, which limits efficiency, scalability, and usability. Thus, we introduce OneTrackerV2, a unified multi-modal tracking framework that enables end-to-end training for any modality. We propose Meta Merger to embed multi-modal information into a unified space, allowing flexible modality fusion and robustness. We further introduce Dual Mixture-of-Experts (DMoE): T-MoE models spatio-temporal relations for tracking, while M-MoE embeds multi-modal knowledge, disentangling cross-modal dependencies and reducing feature conflicts. With a shared architecture, unified parameters, and a single end-to-end training, OneTrackerV2 achieves state-of-the-art performance across five RGB and RGB+X tracking tasks and 12 benchmarks, while maintaining high inference efficiency. Notably, even after model compression, OneTrackerV2 retains strong performance. Moreover, OneTrackerV2 demonstrates remarkable robustness under modality-missing scenarios.

cs.CV

LingoLoop Attack: Trapping MLLMs via Linguistic Context and State Entrapment into Endless Loops

Multimodal Large Language Models (MLLMs) have shown great promise but require substantial computational resources during inference. Attackers can exploit this by inducing excessive output, leading to resource exhaustion and service degradation. Prior energy-latency attacks aim to increase generation time by broadly shifting the output token distribution away from the EOS token, but they neglect the influence of token-level Part-of-Speech (POS) characteristics on EOS and sentence-level structural patterns on output counts, limiting their efficacy. To address this, we propose LingoLoop, an attack designed to induce MLLMs to generate excessively verbose and repetitive sequences. First, we find that the POS tag of a token strongly affects the likelihood of generating an EOS token. Based on this insight, we propose a POS-Aware Delay Mechanism to postpone EOS token generation by adjusting attention weights guided by POS information. Second, we identify that constraining output diversity to induce repetitive loops is effective for sustained generation. We introduce a Generative Path Pruning Mechanism that limits the magnitude of hidden states, encouraging the model to produce persistent loops. Extensive experiments on models like Qwen2.5-VL-3B demonstrate LingoLoop's powerful ability to trap them in generative loops; it consistently drives them to their generation limits and, when those limits are relaxed, can induce outputs with up to 367x more tokens than clean inputs, triggering a commensurate surge in energy consumption. These findings expose significant MLLMs' vulnerabilities, posing challenges for their reliable deployment.

cs.CL

ImmunoNX: a robust bioinformatics workflow to support personalized neoantigen vaccine trials

Personalized neoantigen vaccines represent a promising immunotherapy approach that harnesses tumor-specific antigens to stimulate anti-tumor immune responses. However, the design of these vaccines requires sophisticated computational workflows to predict and prioritize neoantigen candidates from patient sequencing data, coupled with rigorous review to ensure candidate quality. While numerous computational tools exist for neoantigen prediction, to our knowledge, there are no established protocols detailing the complete process from raw sequencing data through systematic candidate selection. Here, we present ImmunoNX (Immunogenomics Neoantigen eXplorer), an end-to-end protocol for neoantigen prediction and vaccine design that has supported over 185 patients across 11 clinical trials. The workflow integrates tumor DNA/RNA and matched normal DNA sequencing data through a computational pipeline built with Workflow Definition Language (WDL) and executed via Cromwell on Google Cloud Platform. ImmunoNX employs consensus-based variant calling, in-silico HLA typing, and pVACtools for neoantigen prediction. Additionally, we describe a two-stage immunogenomics review process with prioritization of neoantigen candidates, enabled by pVACview, followed by manual assessment of variants using the Integrative Genomics Viewer (IGV). This workflow enables vaccine design in under three months. We demonstrate the protocol using the HCC1395 breast cancer cell line dataset, identifying 78 high-confidence neoantigen candidates from 322 initial predictions. Although demonstrated here for vaccine development, this workflow can be adapted for diverse neoantigen therapies and experiments. Therefore, this protocol provides the research community with a reproducible, version-controlled framework for designing personalized neoantigen vaccines, supported by detailed documentation, example datasets, and open-source code.

q-bio.GN

Seeing is Believing: Rich-Context Hallucination Detection for MLLMs via Backward Visual Grounding

Multimodal Large Language Models (MLLMs) have unlocked powerful cross-modal capabilities, but still significantly suffer from hallucinations. As such, accurate detection of hallucinations in MLLMs is imperative for ensuring their reliability in practical applications. To this end, guided by the principle of "Seeing is Believing", we introduce VBackChecker, a novel reference-free hallucination detection framework that verifies the consistency of MLLMgenerated responses with visual inputs, by leveraging a pixellevel Grounding LLM equipped with reasoning and referring segmentation capabilities. This reference-free framework not only effectively handles rich-context scenarios, but also offers interpretability. To facilitate this, an innovative pipeline is accordingly designed for generating instruction-tuning data (R-Instruct), featuring rich-context descriptions, grounding masks, and hard negative samples. We further establish R^2 -HalBench, a new hallucination benchmark for MLLMs, which, unlike previous benchmarks, encompasses real-world, rich-context descriptions from 18 MLLMs with high-quality annotations, spanning diverse object-, attribute, and relationship-level details. VBackChecker outperforms prior complex frameworks and achieves state-of-the-art performance on R^2 -HalBench, even rivaling GPT-4o's capabilities in hallucination detection. It also surpasses prior methods in the pixel-level grounding task, achieving over a 10% improvement. All codes, data, and models are available at https://github.com/PinxueGuo/VBackChecker.

cs.CL

Improving Adversarial Transferability with Neighbourhood Gradient Information

Deep neural networks (DNNs) are known to be susceptible to adversarial examples, leading to significant performance degradation. In black-box attack scenarios, a considerable attack performance gap between the surrogate model and the target model persists. This work focuses on enhancing the transferability of adversarial examples to narrow this performance gap. We observe that the gradient information around the clean image, i.e., Neighbourhood Gradient Information (NGI), can offer high transferability.Based on this insight, we introduce NGI-Attack, incorporating Example Backtracking and Multiplex Mask strategies to exploit this gradient information and enhance transferability. Specifically, we first adopt Example Backtracking to accumulate Neighbourhood Gradient Information as the initial momentum term. Then, we utilize Multiplex Mask to form a multi-way attack strategy that forces the network to focus on non-discriminative regions, which can obtain richer gradient information during only a few iterations. Extensive experiments demonstrate that our approach significantly enhances adversarial transferability. Especially, when attacking numerous defense models, we achieve an average attack success rate of 95.2%. Notably, our method can seamlessly integrate with any off-the-shelf algorithm, enhancing their attack performance without incurring extra time costs.

cs.CV

Controlling few-body reaction pathways using a Feshbach resonance

Gaining control over chemical reactions on the quantum level is a central goal of the modern field of cold and ultracold chemistry. Here, we demonstrate a novel method to coherently steer reaction flux of a three-body recombination process across different product spin channels. For this, we employ a magnetically-tunable Feshbach resonance to admix, in a controlled way, a specific spin state to the reacting collision complex. This allows for the control of the reaction flux into the admixed spin channel, which can be used to significantly change the reaction products. Furthermore, we also investigate the influence of an Efimov resonance on the reaction dynamics. We find that while the Efimov resonance can be used to globally enhance three-body recombination, the relative flux between the reaction channels remains unchanged. Our control scheme is general and can be extended to other reaction processes. It also provides new opportunities in combination with other control schemes, such as quantum interference of reaction paths.

cond-mat.quant-gas

Synthesizing Near-Boundary OOD Samples for Out-of-Distribution Detection

Pre-trained vision-language models have exhibited remarkable abilities in detecting out-of-distribution (OOD) samples. However, some challenging OOD samples, which lie close to in-distribution (InD) data in image feature space, can still lead to misclassification. The emergence of foundation models like diffusion models and multimodal large language models (MLLMs) offers a potential solution to this issue. In this work, we propose SynOOD, a novel approach that harnesses foundation models to generate synthetic, challenging OOD data for fine-tuning CLIP models, thereby enhancing boundary-level discrimination between InD and OOD samples. Our method uses an iterative in-painting process guided by contextual prompts from MLLMs to produce nuanced, boundary-aligned OOD samples. These samples are refined through noise adjustments based on gradients from OOD scores like the energy score, effectively sampling from the InD/OOD boundary. With these carefully synthesized images, we fine-tune the CLIP image encoder and negative label features derived from the text encoder to strengthen connections between near-boundary OOD samples and a set of negative labels. Finally, SynOOD achieves state-of-the-art performance on the large-scale ImageNet benchmark, with minimal increases in parameters and runtime. Our approach significantly surpasses existing methods, and the code is available at https://github.com/Jarvisgivemeasuit/SynOOD.

cs.CV

General Compression Framework for Efficient Transformer Object Tracking

Previous works have attempted to improve tracking efficiency through lightweight architecture design or knowledge distillation from teacher models to compact student trackers. However, these solutions often sacrifice accuracy for speed to a great extent, and also have the problems of complex training process and structural limitations. Thus, we propose a general model compression framework for efficient transformer object tracking, named CompressTracker, to reduce model size while preserving tracking accuracy. Our approach features a novel stage division strategy that segments the transformer layers of the teacher model into distinct stages to break the limitation of model structure. Additionally, we also design a unique replacement training technique that randomly substitutes specific stages in the student model with those from the teacher model, as opposed to training the student model in isolation. Replacement training enhances the student model's ability to replicate the teacher model's behavior and simplifies the training process. To further forcing student model to emulate teacher model, we incorporate prediction guidance and stage-wise feature mimicking to provide additional supervision during the teacher model's compression process. CompressTracker is structurally agnostic, making it compatible with any transformer architecture. We conduct a series of experiment to verify the effectiveness and generalizability of our CompressTracker. Our CompressTracker-SUTrack, compressed from SUTrack, retains about 99 performance on LaSOT (72.2 AUC) while achieves 2.42x speed up. Code is available at https://github.com/LingyiHongfd/CompressTracker.

cs.CV

Enhancing Diffusion-based Unrestricted Adversarial Attacks via Adversary Preferences Alignment

Preference alignment in diffusion models has primarily focused on benign human preferences (e.g., aesthetic). In this paper, we propose a novel perspective: framing unrestricted adversarial example generation as a problem of aligning with adversary preferences. Unlike benign alignment, adversarial alignment involves two inherently conflicting preferences: visual consistency and attack effectiveness, which often lead to unstable optimization and reward hacking (e.g., reducing visual quality to improve attack success). To address this, we propose APA (Adversary Preferences Alignment), a two-stage framework that decouples conflicting preferences and optimizes each with differentiable rewards. In the first stage, APA fine-tunes LoRA to improve visual consistency using rule-based similarity reward. In the second stage, APA updates either the image latent or prompt embedding based on feedback from a substitute classifier, guided by trajectory-level and step-wise rewards. To enhance black-box transferability, we further incorporate a diffusion augmentation strategy. Experiments demonstrate that APA achieves significantly better attack transferability while maintaining high visual consistency, inspiring further research to approach adversarial attacks from an alignment perspective. Code will be available at https://github.com/deep-kaixun/APA.

cs.CV

VideoPure: Diffusion-based Adversarial Purification for Video Recognition

Recent work indicates that video recognition models are vulnerable to adversarial examples, posing a serious security risk to downstream applications. However, current research has primarily focused on adversarial attacks, with limited work exploring defense mechanisms. Furthermore, due to the spatial-temporal complexity of videos, existing video defense methods face issues of high cost, overfitting, and limited defense performance. Recently, diffusion-based adversarial purification methods have achieved robust defense performance in the image domain. However, due to the additional temporal dimension in videos, directly applying these diffusion-based adversarial purification methods to the video domain suffers performance and efficiency degradation. To achieve an efficient and effective video adversarial defense method, we propose the first diffusion-based video purification framework to improve video recognition models' adversarial robustness: VideoPure. Given an adversarial example, we first employ temporal DDIM inversion to transform the input distribution into a temporally consistent and trajectory-defined distribution, covering adversarial noise while preserving more video structure. Then, during DDIM denoising, we leverage intermediate results at each denoising step and conduct guided spatial-temporal optimization, removing adversarial noise while maintaining temporal consistency. Finally, we input the list of optimized intermediate results into the video recognition model for multi-step voting to obtain the predicted class. We investigate the defense performance of our method against black-box, gray-box, and adaptive attacks on benchmark datasets and models. Compared with other adversarial purification methods, our method overall demonstrates better defense performance against different attacks. Our code is available at https://github.com/deep-kaixun/VideoPure.

cs.CV

DeTrack: In-model Latent Denoising Learning for Visual Object Tracking

Previous visual object tracking methods employ image-feature regression models or coordinate autoregression models for bounding box prediction. Image-feature regression methods heavily depend on matching results and do not utilize positional prior, while the autoregressive approach can only be trained using bounding boxes available in the training set, potentially resulting in suboptimal performance during testing with unseen data. Inspired by the diffusion model, denoising learning enhances the model's robustness to unseen data. Therefore, We introduce noise to bounding boxes, generating noisy boxes for training, thus enhancing model robustness on testing data. We propose a new paradigm to formulate the visual object tracking problem as a denoising learning process. However, tracking algorithms are usually asked to run in real-time, directly applying the diffusion model to object tracking would severely impair tracking speed. Therefore, we decompose the denoising learning process into every denoising block within a model, not by running the model multiple times, and thus we summarize the proposed paradigm as an in-model latent denoising learning process. Specifically, we propose a denoising Vision Transformer (ViT), which is composed of multiple denoising blocks. In the denoising block, template and search embeddings are projected into every denoising block as conditions. A denoising block is responsible for removing the noise in a predicted bounding box, and multiple stacked denoising blocks cooperate to accomplish the whole denoising process. Subsequently, we utilize image features and trajectory information to refine the denoised bounding box. Besides, we also utilize trajectory memory and visual memory to improve tracking stability. Experimental results validate the effectiveness of our approach, achieving competitive performance on several challenging datasets.

cs.CV

X-Prompt: Multi-modal Visual Prompt for Video Object Segmentation

Multi-modal Video Object Segmentation (VOS), including RGB-Thermal, RGB-Depth, and RGB-Event, has garnered attention due to its capability to address challenging scenarios where traditional VOS methods struggle, such as extreme illumination, rapid motion, and background distraction. Existing approaches often involve designing specific additional branches and performing full-parameter fine-tuning for fusion in each task. However, this paradigm not only duplicates research efforts and hardware costs but also risks model collapse with the limited multi-modal annotated data. In this paper, we propose a universal framework named X-Prompt for all multi-modal video object segmentation tasks, designated as RGB+X. The X-Prompt framework first pre-trains a video object segmentation foundation model using RGB data, and then utilize the additional modality of the prompt to adapt it to downstream multi-modal tasks with limited data. Within the X-Prompt framework, we introduce the Multi-modal Visual Prompter (MVP), which allows prompting foundation model with the various modalities to segment objects precisely. We further propose the Multi-modal Adaptation Experts (MAEs) to adapt the foundation model with pluggable modality-specific knowledge without compromising the generalization capacity. To evaluate the effectiveness of the X-Prompt framework, we conduct extensive experiments on 3 tasks across 4 benchmarks. The proposed universal X-Prompt framework consistently outperforms the full fine-tuning paradigm and achieves state-of-the-art performance. Code: https://github.com/PinxueGuo/X-Prompt.git

cs.CV

TagOOD: A Novel Approach to Out-of-Distribution Detection via Vision-Language Representations and Class Center Learning

Multimodal fusion, leveraging data like vision and language, is rapidly gaining traction. This enriched data representation improves performance across various tasks. Existing methods for out-of-distribution (OOD) detection, a critical area where AI models encounter unseen data in real-world scenarios, rely heavily on whole-image features. These image-level features can include irrelevant information that hinders the detection of OOD samples, ultimately limiting overall performance. In this paper, we propose \textbf{TagOOD}, a novel approach for OOD detection that leverages vision-language representations to achieve label-free object feature decoupling from whole images. This decomposition enables a more focused analysis of object semantics, enhancing OOD detection performance. Subsequently, TagOOD trains a lightweight network on the extracted object features to learn representative class centers. These centers capture the central tendencies of IND object classes, minimizing the influence of irrelevant image features during OOD detection. Finally, our approach efficiently detects OOD samples by calculating distance-based metrics as OOD scores between learned centers and test samples. We conduct extensive experiments to evaluate TagOOD on several benchmark datasets and demonstrate its superior performance compared to existing OOD detection methods. This work presents a novel perspective for further exploration of multimodal information utilization in OOD detection, with potential applications across various tasks.

cs.CV

Hierarchical Visual Categories Modeling: A Joint Representation Learning and Density Estimation Framework for Out-of-Distribution Detection

Detecting out-of-distribution inputs for visual recognition models has become critical in safe deep learning. This paper proposes a novel hierarchical visual category modeling scheme to separate out-of-distribution data from in-distribution data through joint representation learning and statistical modeling. We learn a mixture of Gaussian models for each in-distribution category. There are many Gaussian mixture models to model different visual categories. With these Gaussian models, we design an in-distribution score function by aggregating multiple Mahalanobis-based metrics. We don't use any auxiliary outlier data as training samples, which may hurt the generalization ability of out-of-distribution detection algorithms. We split the ImageNet-1k dataset into ten folds randomly. We use one fold as the in-distribution dataset and the others as out-of-distribution datasets to evaluate the proposed method. We also conduct experiments on seven popular benchmarks, including CIFAR, iNaturalist, SUN, Places, Textures, ImageNet-O, and OpenImage-O. Extensive experiments indicate that the proposed method outperforms state-of-the-art algorithms clearly. Meanwhile, we find that our visual representation has a competitive performance when compared with features learned by classical methods. These results demonstrate that the proposed method hasn't weakened the discriminative ability of visual recognition models and keeps high efficiency in detecting out-of-distribution samples.

cs.CV