arXiv subjects

Jingshan Zhong

Publications and source records attributed to Jingshan Zhong.

5 recordsLinked to original sources

arXiv2024

High-fidelity near-diffraction-limited projection through scattering with reference-less transmission matrix

Image projection through scattering media has applications ranging from light delivery through multimode fiber to near-eye displays. Conventional methods utilize the transmission matrix (TM) measured by interfering with a reference beam. However, it is noise-sensitive, often resulting in artifacts that degrade the projection quality. Here we propose to characterize the scattering by computationally retrieving TM from intensity-only measurements and solve the projection problem formulated with the retrieved TM by optimization. We experimentally validate the proposed method by projecting through a multimode fiber. Compared to the conventional methods, it projects improved-quality images with resolution near to the diffraction limit, and simplifies the experimental setup by eliminating the reference. It paves the way for applications of high-quality near-diffraction-limited projection through scattering.

physics.optics↗

arXiv2023

Efficient reference-less transmission matrix retrieval for a multimode fiber using fast Fourier transform

Transmission matrix (TM) linearly maps the incident and transmitted complex fields, and has been used widely due to its ability to characterize scattering media. It is computationally demanding to reconstruct the TM from intensity images measured by a reference-less experimental setup. Removing reference beam for interference gains the advantage of simple experimental setup. However, the long computational time still limits its practical application. We propose an efficient reference-less TM retrieval method for multimode fiber (MMF). Our method adopts a data acquisition scheme which employs Fourier transform matrix in the design of the incident fields. We develop a nonlinear optimization algorithm to solve the TM retrieval problem in a parallel manner. The data acquisition scheme allows the algorithm to be implemented with fast Fourier transform (FFT), and hence achieves great efficiency improvement. Further, our method acquires intensity images at a defocus plane and correct the error of relative phase offset of TM recovered from the intensity images measured at one fixed plane. We validate the proposed TM retrieval method with both simulations and experiments. By using FFT, our TM retrieval algorithm achieves 1200x speed-up in computational time, and recovers $2286 \times 8192$ TM of a 0.22 NA and $50 \ μm$ diameter MMF with 124.9 seconds by a computer of 32 CPU cores. With the advantages of efficiency and the correction of phase offset, our method paves the way for the application of reference-less TM retrieval in real practice.

physics.optics↗

arXiv2017

Multiplexed phase-space imaging for 3D fluorescence microscopy

Optical phase-space functions describe spatial and angular information simultaneously; examples include light fields in ray optics and Wigner functions in wave optics. Measurement of phase-space enables digital refocusing, aberration removal and 3D reconstruction. High-resolution capture of 4D phase-space datasets is, however, challenging. Previous scanning approaches are slow, light inefficient and do not achieve diffraction-limited resolution. Here, we propose a multiplexed method that solves these problems. We use a spatial light modulator (SLM) in the pupil plane of a microscope in order to sequentially pattern multiplexed coded apertures while capturing images in real space. Then, we reconstruct the 3D fluorescence distribution of our sample by solving an inverse problem via regularized least squares with a proximal accelerated gradient descent solver. We experimentally reconstruct a 101-Megavoxel 3D volume ($1010\times510\times500μ$m with NA 0.4), demonstrating improved acquisition time, light throughput and resolution compared to scanning aperture methods. Our flexible patterning scheme further allows sparsity in the sample to be exploited for reduced data capture.

physics.optics↗

arXiv2015

Experimental robustness of Fourier Ptychography phase retrieval algorithms

Fourier ptychography is a new computational microscopy technique that provides gigapixel-scale intensity and phase images with both wide field-of-view and high resolution. By capturing a stack of low-resolution images under different illumination angles, a nonlinear inverse algorithm can be used to computationally reconstruct the high-resolution complex field. Here, we compare and classify multiple proposed inverse algorithms in terms of experimental robustness. We find that the main sources of error are noise, aberrations and mis-calibration (i.e. model mis-match). Using simulations and experiments, we demonstrate that the choice of cost function plays a critical role, with amplitude-based cost functions performing better than intensity-based ones. The reason for this is that Fourier ptychography datasets consist of images from both brightfield and darkfield illumination, representing a large range of measured intensities. Both noise (e.g. Poisson noise) and model mis-match errors are shown to scale with intensity. Hence, algorithms that use an appropriate cost function will be more tolerant to both noise and model mis-match. Given these insights, we propose a global Newton's method algorithm which is robust and computationally efficient. Finally, we discuss the impact of procedures for algorithmic correction of aberrations and mis-calibration.

physics.optics↗

arXiv2015

Computational illumination for high-speed in vitro Fourier ptychographic microscopy

We demonstrate a new computational illumination technique that achieves large space-bandwidth-time product, for quantitative phase imaging of unstained live samples in vitro. Microscope lenses can have either large field of view (FOV) or high resolution, not both. Fourier ptychographic microscopy (FPM) is a new computational imaging technique that circumvents this limit by fusing information from multiple images taken with different illumination angles. The result is a gigapixel-scale image having both wide FOV and high resolution, i.e. large space-bandwidth product (SBP). FPM has enormous potential for revolutionizing microscopy and has already found application in digital pathology. However, it suffers from long acquisition times (on the order of minutes), limiting throughput. Faster capture times would not only improve imaging speed, but also allow studies of live samples, where motion artifacts degrade results. In contrast to fixed (e.g. pathology) slides, live samples are continuously evolving at various spatial and temporal scales. Here, we present a new source coding scheme, along with real-time hardware control, to achieve 0.8 NA resolution across a 4x FOV with sub-second capture times. We propose an improved algorithm and new initialization scheme, which allow robust phase reconstruction over long time-lapse experiments. We present the first FPM results for both growing and confluent in vitro cell cultures, capturing videos of subcellular dynamical phenomena in popular cell lines undergoing division and migration. Our method opens up FPM to applications with live samples, for observing rare events in both space and time.

physics.optics↗