arXiv subjects

Jingsheng Tang

Publications and source records attributed to Jingsheng Tang.

4 recordsLinked to original sources

arXiv2026

OpTI-Mouse: Optimization for Targeted Temporal Interference Stimulation in the Mouse Brain

Temporal Interference (TI) stimulation enables deep brain targeting, yet precise optimization tools for mouse models remain limited. We developed a computational optimization tool integrating mouse head modeling with the optimization algorithm to optimize stimulation strategies for predefined target regions. By balancing target intensity and spatial focality, the optimized strategy significantly outperformed empirical baselines. For the CA3-CA1 target, it achieved a 7-fold intensity increase (10.29 vs. 2.89 V/m) under iso-focality conditions. Conversely, for the Dentate Gyrus, it improved spatial confinement ($r_{0.5}$ reduced from 3.99 to 3.54 mm) while maintaining comparable intensity. Cross-model validation on a standardized Sim4Life phantom further confirmed the framework's robustness. This approach offers a powerful tool for enhancing the precision and reproducibility of preclinical TI stimulation studies.

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arXiv2025

Personalized Transcranial Electrical Stimulation: A Review of Computational Modeling and Optimization

Objective. Personalized transcranial electrical stimulation (tES) has gained growing attention due to the substantial inter-individual variability in brain anatomy and physiology. While previous reviews have discussed the physiological mechanisms and clinical applications of tES, there remains a critical gap in up-to-date syntheses focused on the computational modeling frameworks that enable individualized stimulation optimization. Approach. This review presents a comprehensive overview of recent advances in computational techniques supporting personalized tES. We systematically examine developments in forward modeling for simulating individualized electric fields, as well as inverse modeling approaches for optimizing stimulation parameters. We critically evaluate progress in head modeling pipelines, optimization algorithms, and the integration of multimodal brain data. Main results. Recent advances have substantially accelerated the construction of subject-specific head conductor models and expanded the landscape of optimization methods, including multi-objective optimization and brain network-informed optimization. These advances allow for dynamic and individualized stimulation planning, moving beyond empirical trial-and-error approaches.Significance. By integrating the latest developments in computational modeling for personalized tES, this review highlights current challenges, emerging opportunities, and future directions for achieving precision neuromodulation in both research and clinical contexts.

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arXiv2025

DCA: Graph-Guided Deep Embedding Clustering for Brain Atlases

Brain atlases are essential for reducing the dimensionality of neuroimaging data and enabling interpretable analysis. However, most existing atlases are predefined, group-level templates with limited flexibility and resolution. We present Deep Cluster Atlas (DCA), a graph-guided deep embedding clustering framework for generating individualized, voxel-wise brain parcellations. DCA combines a pretrained autoencoder with spatially regularized deep clustering to produce functionally coherent and spatially contiguous regions. Our method supports flexible control over resolution and anatomical scope, and generalizes to arbitrary brain structures. We further introduce a standardized benchmarking platform for atlas evaluation, using multiple large-scale fMRI datasets. Across multiple datasets and scales, DCA outperforms state-of-the-art atlases, improving functional homogeneity by 98.8% and silhouette coefficient by 29%, and achieves superior performance in downstream tasks such as autism diagnosis and cognitive decoding. We also observe that a fine-tuned pretrained model achieves superior results on the corresponding task. Codes and models are available at https://github.com/ncclab-sustech/DCA .

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arXiv2024

sEMG-based Gesture-Free Hand Intention Recognition: System, Dataset, Toolbox, and Benchmark Results

In sensitive scenarios, such as meetings, negotiations, and team sports, messages must be conveyed without detection by non-collaborators. Previous methods, such as encrypting messages, eye contact, and micro-gestures, had problems with either inaccurate information transmission or leakage of interaction intentions. To this end, a novel gesture-free hand intention recognition scheme was proposed, that adopted surface electromyography(sEMG) and isometric contraction theory to recognize different hand intentions without any gesture. Specifically, this work includes four parts: (1) the experimental system, consisting of the upper computer software, self-conducted myoelectric watch, and sports platform, is built to get sEMG signals and simulate multiple usage scenarios; (2) the paradigm is designed to standard prompt and collect the gesture-free sEMG datasets. Eight-channel signals of ten subjects were recorded twice per subject at about 5-10 days intervals; (3) the toolbox integrates preprocessing methods (data segmentation, filter, normalization, etc.), commonly used sEMG signal decoding methods, and various plotting functions, to facilitate the research of the dataset; (4) the benchmark results of widely used methods are provided. The results involve single-day, cross-day, and cross-subject experiments of 6-class and 12-class gesture-free hand intention when subjects with different sports motions. To help future research, all data, hardware, software, and methods are open-sourced on the following website: click here.

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