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Jingyang Zhang

Publications and source records attributed to Jingyang Zhang.

At least 55 records · Page 3Linked to original sources

3DSAM-adapter: Holistic adaptation of SAM from 2D to 3D for promptable tumor segmentation

Despite that the segment anything model (SAM) achieved impressive results on general-purpose semantic segmentation with strong generalization ability on daily images, its demonstrated performance on medical image segmentation is less precise and not stable, especially when dealing with tumor segmentation tasks that involve objects of small sizes, irregular shapes, and low contrast. Notably, the original SAM architecture is designed for 2D natural images, therefore would not be able to extract the 3D spatial information from volumetric medical data effectively. In this paper, we propose a novel adaptation method for transferring SAM from 2D to 3D for promptable medical image segmentation. Through a holistically designed scheme for architecture modification, we transfer the SAM to support volumetric inputs while retaining the majority of its pre-trained parameters for reuse. The fine-tuning process is conducted in a parameter-efficient manner, wherein most of the pre-trained parameters remain frozen, and only a few lightweight spatial adapters are introduced and tuned. Regardless of the domain gap between natural and medical data and the disparity in the spatial arrangement between 2D and 3D, the transformer trained on natural images can effectively capture the spatial patterns present in volumetric medical images with only lightweight adaptations. We conduct experiments on four open-source tumor segmentation datasets, and with a single click prompt, our model can outperform domain state-of-the-art medical image segmentation models on 3 out of 4 tasks, specifically by 8.25%, 29.87%, and 10.11% for kidney tumor, pancreas tumor, colon cancer segmentation, and achieve similar performance for liver tumor segmentation. We also compare our adaptation method with existing popular adapters, and observed significant performance improvement on most datasets.

cs.CV↗

S^2Former-OR: Single-Stage Bi-Modal Transformer for Scene Graph Generation in OR

Scene graph generation (SGG) of surgical procedures is crucial in enhancing holistically cognitive intelligence in the operating room (OR). However, previous works have primarily relied on multi-stage learning, where the generated semantic scene graphs depend on intermediate processes with pose estimation and object detection. This pipeline may potentially compromise the flexibility of learning multimodal representations, consequently constraining the overall effectiveness. In this study, we introduce a novel single-stage bi-modal transformer framework for SGG in the OR, termed S^2Former-OR, aimed to complementally leverage multi-view 2D scenes and 3D point clouds for SGG in an end-to-end manner. Concretely, our model embraces a View-Sync Transfusion scheme to encourage multi-view visual information interaction. Concurrently, a Geometry-Visual Cohesion operation is designed to integrate the synergic 2D semantic features into 3D point cloud features. Moreover, based on the augmented feature, we propose a novel relation-sensitive transformer decoder that embeds dynamic entity-pair queries and relational trait priors, which enables the direct prediction of entity-pair relations for graph generation without intermediate steps. Extensive experiments have validated the superior SGG performance and lower computational cost of S^2Former-OR on 4D-OR benchmark, compared with current OR-SGG methods, e.g., 3 percentage points Precision increase and 24.2M reduction in model parameters. We further compared our method with generic single-stage SGG methods with broader metrics for a comprehensive evaluation, with consistently better performance achieved.

cs.CV↗

Comprehensive Generative Replay for Task-Incremental Segmentation with Concurrent Appearance and Semantic Forgetting

Generalist segmentation models are increasingly favored for diverse tasks involving various objects from different image sources. Task-Incremental Learning (TIL) offers a privacy-preserving training paradigm using tasks arriving sequentially, instead of gathering them due to strict data sharing policies. However, the task evolution can span a wide scope that involves shifts in both image appearance and segmentation semantics with intricate correlation, causing concurrent appearance and semantic forgetting. To solve this issue, we propose a Comprehensive Generative Replay (CGR) framework that restores appearance and semantic knowledge by synthesizing image-mask pairs to mimic past task data, which focuses on two aspects: modeling image-mask correspondence and promoting scalability for diverse tasks. Specifically, we introduce a novel Bayesian Joint Diffusion (BJD) model for high-quality synthesis of image-mask pairs with their correspondence explicitly preserved by conditional denoising. Furthermore, we develop a Task-Oriented Adapter (TOA) that recalibrates prompt embeddings to modulate the diffusion model, making the data synthesis compatible with different tasks. Experiments on incremental tasks (cardiac, fundus and prostate segmentation) show its clear advantage for alleviating concurrent appearance and semantic forgetting. Code is available at https://github.com/jingyzhang/CGR.

eess.IV↗

SD-NAE: Generating Natural Adversarial Examples with Stable Diffusion

Natural Adversarial Examples (NAEs), images arising naturally from the environment and capable of deceiving classifiers, are instrumental in robustly evaluating and identifying vulnerabilities in trained models. In this work, unlike prior works that passively collect NAEs from real images, we propose to actively synthesize NAEs using the state-of-the-art Stable Diffusion. Specifically, our method formulates a controlled optimization process, where we perturb the token embedding that corresponds to a specified class to generate NAEs. This generation process is guided by the gradient of loss from the target classifier, ensuring that the created image closely mimics the ground-truth class yet fools the classifier. Named SD-NAE (Stable Diffusion for Natural Adversarial Examples), our innovative method is effective in producing valid and useful NAEs, which is demonstrated through a meticulously designed experiment. Code is available at https://github.com/linyueqian/SD-NAE.

cs.CV↗

OSR-ViT: A Simple and Modular Framework for Open-Set Object Detection and Discovery

An object detector's ability to detect and flag \textit{novel} objects during open-world deployments is critical for many real-world applications. Unfortunately, much of the work in open object detection today is disjointed and fails to adequately address applications that prioritize unknown object recall \textit{in addition to} known-class accuracy. To close this gap, we present a new task called Open-Set Object Detection and Discovery (OSODD) and as a solution propose the Open-Set Regions with ViT features (OSR-ViT) detection framework. OSR-ViT combines a class-agnostic proposal network with a powerful ViT-based classifier. Its modular design simplifies optimization and allows users to easily swap proposal solutions and feature extractors to best suit their application. Using our multifaceted evaluation protocol, we show that OSR-ViT obtains performance levels that far exceed state-of-the-art supervised methods. Our method also excels in low-data settings, outperforming supervised baselines using a fraction of the training data.

cs.CV↗

Direct2.5: Diverse Text-to-3D Generation via Multi-view 2.5D Diffusion

Recent advances in generative AI have unveiled significant potential for the creation of 3D content. However, current methods either apply a pre-trained 2D diffusion model with the time-consuming score distillation sampling (SDS), or a direct 3D diffusion model trained on limited 3D data losing generation diversity. In this work, we approach the problem by employing a multi-view 2.5D diffusion fine-tuned from a pre-trained 2D diffusion model. The multi-view 2.5D diffusion directly models the structural distribution of 3D data, while still maintaining the strong generalization ability of the original 2D diffusion model, filling the gap between 2D diffusion-based and direct 3D diffusion-based methods for 3D content generation. During inference, multi-view normal maps are generated using the 2.5D diffusion, and a novel differentiable rasterization scheme is introduced to fuse the almost consistent multi-view normal maps into a consistent 3D model. We further design a normal-conditioned multi-view image generation module for fast appearance generation given the 3D geometry. Our method is a one-pass diffusion process and does not require any SDS optimization as post-processing. We demonstrate through extensive experiments that, our direct 2.5D generation with the specially-designed fusion scheme can achieve diverse, mode-seeking-free, and high-fidelity 3D content generation in only 10 seconds. Project page: https://nju-3dv.github.io/projects/direct25.

cs.CV↗

JointNet: Extending Text-to-Image Diffusion for Dense Distribution Modeling

We introduce JointNet, a novel neural network architecture for modeling the joint distribution of images and an additional dense modality (e.g., depth maps). JointNet is extended from a pre-trained text-to-image diffusion model, where a copy of the original network is created for the new dense modality branch and is densely connected with the RGB branch. The RGB branch is locked during network fine-tuning, which enables efficient learning of the new modality distribution while maintaining the strong generalization ability of the large-scale pre-trained diffusion model. We demonstrate the effectiveness of JointNet by using RGBD diffusion as an example and through extensive experiments, showcasing its applicability in a variety of applications, including joint RGBD generation, dense depth prediction, depth-conditioned image generation, and coherent tile-based 3D panorama generation.

cs.CV↗

Construction of unbiased dental template and parametric dental model for precision digital dentistry

Dental template and parametric dental models are important tools for various applications in digital dentistry. However, constructing an unbiased dental template and accurate parametric dental models remains a challenging task due to the complex anatomical and morphological dental structures and also low volume ratio of the teeth. In this study, we develop an unbiased dental template by constructing an accurate dental atlas from CBCT images with guidance of teeth segmentation. First, to address the challenges, we propose to enhance the CBCT images and their segmentation images, including image cropping, image masking and segmentation intensity reassigning. Then, we further use the segmentation images to perform co-registration with the CBCT images to generate an accurate dental atlas, from which an unbiased dental template can be generated. By leveraging the unbiased dental template, we construct parametric dental models by estimating point-to-point correspondences between the dental models and employing Principal Component Analysis to determine shape subspaces of the parametric dental models. A total of 159 CBCT images of real subjects are collected to perform the constructions. Experimental results demonstrate effectiveness of our proposed method in constructing unbiased dental template and parametric dental model. The developed dental template and parametric dental models are available at https://github.com/Marvin0724/Teeth_template.

cs.CV↗

NeILF++: Inter-Reflectable Light Fields for Geometry and Material Estimation

We present a novel differentiable rendering framework for joint geometry, material, and lighting estimation from multi-view images. In contrast to previous methods which assume a simplified environment map or co-located flashlights, in this work, we formulate the lighting of a static scene as one neural incident light field (NeILF) and one outgoing neural radiance field (NeRF). The key insight of the proposed method is the union of the incident and outgoing light fields through physically-based rendering and inter-reflections between surfaces, making it possible to disentangle the scene geometry, material, and lighting from image observations in a physically-based manner. The proposed incident light and inter-reflection framework can be easily applied to other NeRF systems. We show that our method can not only decompose the outgoing radiance into incident lights and surface materials, but also serve as a surface refinement module that further improves the reconstruction detail of the neural surface. We demonstrate on several datasets that the proposed method is able to achieve state-of-the-art results in terms of geometry reconstruction quality, material estimation accuracy, and the fidelity of novel view rendering.

cs.CV↗

SIO: Synthetic In-Distribution Data Benefits Out-of-Distribution Detection

Building up reliable Out-of-Distribution (OOD) detectors is challenging, often requiring the use of OOD data during training. In this work, we develop a data-driven approach which is distinct and complementary to existing works: Instead of using external OOD data, we fully exploit the internal in-distribution (ID) training set by utilizing generative models to produce additional synthetic ID images. The classifier is then trained using a novel objective that computes weighted loss on real and synthetic ID samples together. Our training framework, which is termed SIO, serves as a "plug-and-play" technique that is designed to be compatible with existing and future OOD detection algorithms, including the ones that leverage available OOD training data. Our experiments on CIFAR-10, CIFAR-100, and ImageNet variants demonstrate that SIO consistently improves the performance of nearly all state-of-the-art (SOTA) OOD detection algorithms. For instance, on the challenging CIFAR-10 v.s. CIFAR-100 detection problem, SIO improves the average OOD detection AUROC of 18 existing methods from 86.25\% to 89.04\% and achieves a new SOTA of 92.94\% according to the OpenOOD benchmark. Code is available at https://github.com/zjysteven/SIO.

cs.CV↗

Structure-aware registration network for liver DCE-CT images

Image registration of liver dynamic contrast-enhanced computed tomography (DCE-CT) is crucial for diagnosis and image-guided surgical planning of liver cancer. However, intensity variations due to the flow of contrast agents combined with complex spatial motion induced by respiration brings great challenge to existing intensity-based registration methods. To address these problems, we propose a novel structure-aware registration method by incorporating structural information of related organs with segmentation-guided deep registration network. Existing segmentation-guided registration methods only focus on volumetric registration inside the paired organ segmentations, ignoring the inherent attributes of their anatomical structures. In addition, such paired organ segmentations are not always available in DCE-CT images due to the flow of contrast agents. Different from existing segmentation-guided registration methods, our proposed method extracts structural information in hierarchical geometric perspectives of line and surface. Then, according to the extracted structural information, structure-aware constraints are constructed and imposed on the forward and backward deformation field simultaneously. In this way, all available organ segmentations, including unpaired ones, can be fully utilized to avoid the side effect of contrast agent and preserve the topology of organs during registration. Extensive experiments on an in-house liver DCE-CT dataset and a public LiTS dataset show that our proposed method can achieve higher registration accuracy and preserve anatomical structure more effectively than state-of-the-art methods.

eess.IV↗

Deep learning reveals the common spectrum underlying multiple brain disorders in youth and elders from brain functional networks

Brain disorders in the early and late life of humans potentially share pathological alterations in brain functions. However, the key evidence from neuroimaging data for pathological commonness remains unrevealed. To explore this hypothesis, we build a deep learning model, using multi-site functional magnetic resonance imaging data (N=4,410, 6 sites), for classifying 5 different brain disorders from healthy controls, with a set of common features. Our model achieves 62.6(1.9)% overall classification accuracy on data from the 6 investigated sites and detects a set of commonly affected functional subnetworks at different spatial scales, including default mode, executive control, visual, and limbic networks. In the deep-layer feature representation for individual data, we observe young and aging patients with disorders are continuously distributed, which is in line with the clinical concept of the "spectrum of disorders". The revealed spectrum underlying early- and late-life brain disorders promotes the understanding of disorder comorbidities in the lifespan.

cs.AI↗

CDDSA: Contrastive Domain Disentanglement and Style Augmentation for Generalizable Medical Image Segmentation

Generalization to previously unseen images with potential domain shifts and different styles is essential for clinically applicable medical image segmentation, and the ability to disentangle domain-specific and domain-invariant features is key for achieving Domain Generalization (DG). However, existing DG methods can hardly achieve effective disentanglement to get high generalizability. To deal with this problem, we propose an efficient Contrastive Domain Disentanglement and Style Augmentation (CDDSA) framework for generalizable medical image segmentation. First, a disentangle network is proposed to decompose an image into a domain-invariant anatomical representation and a domain-specific style code, where the former is sent to a segmentation model that is not affected by the domain shift, and the disentangle network is regularized by a decoder that combines the anatomical and style codes to reconstruct the input image. Second, to achieve better disentanglement, a contrastive loss is proposed to encourage the style codes from the same domain and different domains to be compact and divergent, respectively. Thirdly, to further improve generalizability, we propose a style augmentation method based on the disentanglement representation to synthesize images in various unseen styles with shared anatomical structures. Our method was validated on a public multi-site fundus image dataset for optic cup and disc segmentation and an in-house multi-site Nasopharyngeal Carcinoma Magnetic Resonance Image (NPC-MRI) dataset for nasopharynx Gross Tumor Volume (GTVnx) segmentation. Experimental results showed that the proposed CDDSA achieved remarkable generalizability across different domains, and it outperformed several state-of-the-art methods in domain-generalizable segmentation.

cs.CV↗

Mixture Outlier Exposure: Towards Out-of-Distribution Detection in Fine-grained Environments

Many real-world scenarios in which DNN-based recognition systems are deployed have inherently fine-grained attributes (e.g., bird-species recognition, medical image classification). In addition to achieving reliable accuracy, a critical subtask for these models is to detect Out-of-distribution (OOD) inputs. Given the nature of the deployment environment, one may expect such OOD inputs to also be fine-grained w.r.t. the known classes (e.g., a novel bird species), which are thus extremely difficult to identify. Unfortunately, OOD detection in fine-grained scenarios remains largely underexplored. In this work, we aim to fill this gap by first carefully constructing four large-scale fine-grained test environments, in which existing methods are shown to have difficulties. Particularly, we find that even explicitly incorporating a diverse set of auxiliary outlier data during training does not provide sufficient coverage over the broad region where fine-grained OOD samples locate. We then propose Mixture Outlier Exposure (MixOE), which mixes ID data and training outliers to expand the coverage of different OOD granularities, and trains the model such that the prediction confidence linearly decays as the input transitions from ID to OOD. Extensive experiments and analyses demonstrate the effectiveness of MixOE for building up OOD detector in fine-grained environments. The code is available at https://github.com/zjysteven/MixOE.

cs.LG↗

Fine-grain Inference on Out-of-Distribution Data with Hierarchical Classification

Machine learning methods must be trusted to make appropriate decisions in real-world environments, even when faced with out-of-distribution (OOD) samples. Many current approaches simply aim to detect OOD examples and alert the user when an unrecognized input is given. However, when the OOD sample significantly overlaps with the training data, a binary anomaly detection is not interpretable or explainable, and provides little information to the user. We propose a new model for OOD detection that makes predictions at varying levels of granularity as the inputs become more ambiguous, the model predictions become coarser and more conservative. Consider an animal classifier that encounters an unknown bird species and a car. Both cases are OOD, but the user gains more information if the classifier recognizes that its uncertainty over the particular species is too large and predicts bird instead of detecting it as OOD. Furthermore, we diagnose the classifiers performance at each level of the hierarchy improving the explainability and interpretability of the models predictions. We demonstrate the effectiveness of hierarchical classifiers for both fine- and coarse-grained OOD tasks.

cs.LG↗

Contrastive Semi-supervised Learning for Domain Adaptive Segmentation Across Similar Anatomical Structures

Convolutional Neural Networks (CNNs) have achieved state-of-the-art performance for medical image segmentation, yet need plenty of manual annotations for training. Semi-Supervised Learning (SSL) methods are promising to reduce the requirement of annotations, but their performance is still limited when the dataset size and the number of annotated images are small. Leveraging existing annotated datasets with similar anatomical structures to assist training has a potential for improving the model's performance. However, it is further challenged by the cross-anatomy domain shift due to the different appearance and even imaging modalities from the target structure. To solve this problem, we propose Contrastive Semi-supervised learning for Cross Anatomy Domain Adaptation (CS-CADA) that adapts a model to segment similar structures in a target domain, which requires only limited annotations in the target domain by leveraging a set of existing annotated images of similar structures in a source domain. We use Domain-Specific Batch Normalization (DSBN) to individually normalize feature maps for the two anatomical domains, and propose a cross-domain contrastive learning strategy to encourage extracting domain invariant features. They are integrated into a Self-Ensembling Mean-Teacher (SE-MT) framework to exploit unlabeled target domain images with a prediction consistency constraint. Extensive experiments show that our CS-CADA is able to solve the challenging cross-anatomy domain shift problem, achieving accurate segmentation of coronary arteries in X-ray images with the help of retinal vessel images and cardiac MR images with the help of fundus images, respectively, given only a small number of annotations in the target domain.

cs.CV↗

Learning towards Synchronous Network Memorizability and Generalizability for Continual Segmentation across Multiple Sites

In clinical practice, a segmentation network is often required to continually learn on a sequential data stream from multiple sites rather than a consolidated set, due to the storage cost and privacy restriction. However, during the continual learning process, existing methods are usually restricted in either network memorizability on previous sites or generalizability on unseen sites. This paper aims to tackle the challenging problem of Synchronous Memorizability and Generalizability (SMG) and to simultaneously improve performance on both previous and unseen sites, with a novel proposed SMG-learning framework. First, we propose a Synchronous Gradient Alignment (SGA) objective, which not only promotes the network memorizability by enforcing coordinated optimization for a small exemplar set from previous sites (called replay buffer), but also enhances the generalizability by facilitating site-invariance under simulated domain shift. Second, to simplify the optimization of SGA objective, we design a Dual-Meta algorithm that approximates the SGA objective as dual meta-objectives for optimization without expensive computation overhead. Third, for efficient rehearsal, we configure the replay buffer comprehensively considering additional inter-site diversity to reduce redundancy. Experiments on prostate MRI data sequentially acquired from six institutes demonstrate that our method can simultaneously achieve higher memorizability and generalizability over state-of-the-art methods. Code is available at https://github.com/jingyzhang/SMG-Learning.

eess.IV↗

Critical Regularizations for Neural Surface Reconstruction in the Wild

Neural implicit functions have recently shown promising results on surface reconstructions from multiple views. However, current methods still suffer from excessive time complexity and poor robustness when reconstructing unbounded or complex scenes. In this paper, we present RegSDF, which shows that proper point cloud supervisions and geometry regularizations are sufficient to produce high-quality and robust reconstruction results. Specifically, RegSDF takes an additional oriented point cloud as input, and optimizes a signed distance field and a surface light field within a differentiable rendering framework. We also introduce the two critical regularizations for this optimization. The first one is the Hessian regularization that smoothly diffuses the signed distance values to the entire distance field given noisy and incomplete input. And the second one is the minimal surface regularization that compactly interpolates and extrapolates the missing geometry. Extensive experiments are conducted on DTU, BlendedMVS, and Tanks and Temples datasets. Compared with recent neural surface reconstruction approaches, RegSDF is able to reconstruct surfaces with fine details even for open scenes with complex topologies and unstructured camera trajectories.

cs.CV↗