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Jinwei Zhang

Publications and source records attributed to Jinwei Zhang.

At least 37 records · Page 2Linked to original sources

DAGrid: Directed Accumulator Grid

Recent research highlights that the Directed Accumulator (DA), through its parametrization of geometric priors into neural networks, has notably improved the performance of medical image recognition, particularly with small and imbalanced datasets. However, DA's potential in pixel-wise dense predictions is unexplored. To bridge this gap, we present the Directed Accumulator Grid (DAGrid), which allows geometric-preserving filtering in neural networks, thus broadening the scope of DA's applications to include pixel-level dense prediction tasks. DAGrid utilizes homogeneous data types in conjunction with designed sampling grids to construct geometrically transformed representations, retaining intricate geometric information and promoting long-range information propagation within the neural networks. Contrary to its symmetric counterpart, grid sampling, which might lose information in the sampling process, DAGrid aggregates all pixels, ensuring a comprehensive representation in the transformed space. The parallelization of DAGrid on modern GPUs is facilitated using CUDA programming, and also back propagation is enabled for deep neural network training. Empirical results show DAGrid-enhanced neural networks excel in supervised skin lesion segmentation and unsupervised cardiac image registration. Specifically, the network incorporating DAGrid has realized a 70.8% reduction in network parameter size and a 96.8% decrease in FLOPs, while concurrently improving the Dice score for skin lesion segmentation by 1.0% compared to state-of-the-art transformers. Furthermore, it has achieved improvements of 4.4% and 8.2% in the average Dice score and Dice score of the left ventricular mass, respectively, indicating an increase in registration accuracy for cardiac images. The source code is available at https://github.com/tinymilky/DeDA.

cs.CV↗

mcLARO: Multi-Contrast Learned Acquisition and Reconstruction Optimization for simultaneous quantitative multi-parametric mapping

Purpose: To develop a method for rapid sub-millimeter T1, T2, T2* and QSM mapping in a single scan using multi-contrast Learned Acquisition and Reconstruction Optimization (mcLARO). Methods: A pulse sequence was developed by interleaving inversion recovery and T2 magnetization preparations and single-echo and multi-echo gradient echo acquisitions, which sensitized k-space data to T1, T2, T2* and magnetic susceptibility. The proposed mcLARO used a deep learning framework to optimize both the multi-contrast k-space under-sampling pattern and the image reconstruction based on image feature fusion. The proposed mcLARO method with R=8 under-sampling was validated in a retrospective ablation study using fully sampled data as reference and evaluated in a prospective study using separately acquired conventionally sampled quantitative maps as reference standard. Results: The retrospective ablation study showed improved image sharpness of mcLARO compared to the baseline network without multi-contrast sampling pattern optimization or image feature fusion, and negligible bias and narrow 95% limits of agreement on regional T1, T2, T2* and QSM values were obtained by the under-sampled reconstructions compared to the fully sampled reconstruction. The prospective study showed small or negligible bias and narrow 95% limits of agreement on regional T1, T2, T2* and QSM values by mcLARO (5:39 mins) compared to reference scans (40:03 mins in total). Conclusion: mcLARO enabled fast sub-millimeter T1, T2, T2* and QSM mapping in a single scan.

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DeDA: Deep Directed Accumulator

Chronic active multiple sclerosis lesions, also termed as rim+ lesions, can be characterized by a hyperintense rim at the edge of the lesion on quantitative susceptibility maps. These rim+ lesions exhibit a geometrically simple structure, where gradients at the lesion edge are radially oriented and a greater magnitude of gradients is observed in contrast to rim- (non rim+) lesions. However, recent studies have shown that the identification performance of such lesions remains unsatisfied due to the limited amount of data and high class imbalance. In this paper, we propose a simple yet effective image processing operation, deep directed accumulator (DeDA), that provides a new perspective for injecting domain-specific inductive biases (priors) into neural networks for rim+ lesion identification. Given a feature map and a set of sampling grids, DeDA creates and quantizes an accumulator space into finite intervals, and accumulates feature values accordingly. This DeDA operation is a generalized discrete Radon transform and can also be regarded as a symmetric operation to the grid sampling within the forward-backward neural network framework, the process of which is order-agnostic, and can be efficiently implemented with the native CUDA programming. Experimental results on a dataset with 177 rim+ and 3986 rim- lesions show that 10.1% of improvement in a partial (false positive rate<0.1) area under the receiver operating characteristic curve (pROC AUC) and 10.2% of improvement in an area under the precision recall curve (PR AUC) can be achieved respectively comparing to other state-of-the-art methods. The source code is available online at https://github.com/tinymilky/DeDA

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Spatially Covariant Lesion Segmentation

Compared to natural images, medical images usually show stronger visual patterns and therefore this adds flexibility and elasticity to resource-limited clinical applications by injecting proper priors into neural networks. In this paper, we propose spatially covariant pixel-aligned classifier (SCP) to improve the computational efficiency and meantime maintain or increase accuracy for lesion segmentation. SCP relaxes the spatial invariance constraint imposed by convolutional operations and optimizes an underlying implicit function that maps image coordinates to network weights, the parameters of which are obtained along with the backbone network training and later used for generating network weights to capture spatially covariant contextual information. We demonstrate the effectiveness and efficiency of the proposed SCP using two lesion segmentation tasks from different imaging modalities: white matter hyperintensity segmentation in magnetic resonance imaging and liver tumor segmentation in contrast-enhanced abdominal computerized tomography. The network using SCP has achieved 23.8%, 64.9% and 74.7% reduction in GPU memory usage, FLOPs, and network size with similar or better accuracy for lesion segmentation.

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LARO: Learned Acquisition and Reconstruction Optimization to accelerate Quantitative Susceptibility Mapping

Quantitative susceptibility mapping (QSM) involves acquisition and reconstruction of a series of images at multi-echo time points to estimate tissue field, which prolongs scan time and requires specific reconstruction technique. In this paper, we present our new framework, called Learned Acquisition and Reconstruction Optimization (LARO), which aims to accelerate the multi-echo gradient echo (mGRE) pulse sequence for QSM. Our approach involves optimizing a Cartesian multi-echo k-space sampling pattern with a deep reconstruction network. Next, this optimized sampling pattern was implemented in an mGRE sequence using Cartesian fan-beam k-space segmenting and ordering for prospective scans. Furthermore, we propose to insert a recurrent temporal feature fusion module into the reconstruction network to capture signal redundancies along echo time. Our ablation studies show that both the optimized sampling pattern and proposed reconstruction strategy help improve the quality of the multi-echo image reconstructions. Generalization experiments show that LARO is robust on the test data with new pathologies and different sequence parameters. Our code is available at https://github.com/Jinwei1209/LARO.git.

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Motion Artifact Reduction in Quantitative Susceptibility Mapping using Deep Neural Network

An approach to reduce motion artifacts in Quantitative Susceptibility Mapping using deep learning is proposed. We use an affine motion model with randomly created motion profiles to simulate motion-corrupted QSM images. The simulated QSM image is paired with its motion-free reference to train a neural network using supervised learning. The trained network is tested on unseen simulated motion-corrupted QSM images, in healthy volunteers and in Parkinson's disease patients. The results show that motion artifacts, such as ringing and ghosting, were successfully suppressed.

physics.med-ph↗

Probabilistic Dipole Inversion for Adaptive Quantitative Susceptibility Mapping

A learning-based posterior distribution estimation method, Probabilistic Dipole Inversion (PDI), is proposed to solve the quantitative susceptibility mapping (QSM) inverse problem in MRI with uncertainty estimation. In PDI, a deep convolutional neural network (CNN) is used to represent the multivariate Gaussian distribution as the approximate posterior distribution of susceptibility given the input measured field. Such CNN is first trained on healthy subjects via posterior density estimation, where the training dataset contains samples from the true posterior distribution. Domain adaptations are then deployed on patient datasets with new pathologies not included in pre-training, where PDI updates the pre-trained CNN's weights in an unsupervised fashion by minimizing the Kullback-Leibler divergence between the approximate posterior distribution represented by CNN and the true posterior distribution from the likelihood distribution of a known physical model and pre-defined prior distribution. Based on our experiments, PDI provides additional uncertainty estimation compared to the conventional MAP approach, while addressing the potential issue of the pre-trained CNN when test data deviates from training.

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Temporal Feature Fusion with Sampling Pattern Optimization for Multi-echo Gradient Echo Acquisition and Image Reconstruction

Quantitative imaging in MRI usually involves acquisition and reconstruction of a series of images at multi-echo time points, which possibly requires more scan time and specific reconstruction technique compared to conventional qualitative imaging. In this work, we focus on optimizing the acquisition and reconstruction process of multi-echo gradient echo pulse sequence for quantitative susceptibility mapping as one important quantitative imaging method in MRI. A multi-echo sampling pattern optimization block extended from LOUPE-ST is proposed to optimize the k-space sampling patterns along echoes. Besides, a recurrent temporal feature fusion block is proposed and inserted into a backbone deep ADMM network to capture the signal evolution along echo time during reconstruction. Experiments show that both blocks help improve multi-echo image reconstruction performance.

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NeRD: Neural Representation of Distribution for Medical Image Segmentation

We introduce Neural Representation of Distribution (NeRD) technique, a module for convolutional neural networks (CNNs) that can estimate the feature distribution by optimizing an underlying function mapping image coordinates to the feature distribution. Using NeRD, we propose an end-to-end deep learning model for medical image segmentation that can compensate the negative impact of feature distribution shifting issue caused by commonly used network operations such as padding and pooling. An implicit function is used to represent the parameter space of the feature distribution by querying the image coordinate. With NeRD, the impact of issues such as over-segmenting and missing have been reduced, and experimental results on the challenging white matter lesion segmentation and left atrial segmentation verify the effectiveness of the proposed method. The code is available via https://github.com/tinymilky/NeRD.

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Geometric Loss for Deep Multiple Sclerosis lesion Segmentation

Multiple sclerosis (MS) lesions occupy a small fraction of the brain volume, and are heterogeneous with regards to shape, size and locations, which poses a great challenge for training deep learning based segmentation models. We proposed a new geometric loss formula to address the data imbalance and exploit the geometric property of MS lesions. We showed that traditional region-based and boundary-aware loss functions can be associated with the formula. We further develop and instantiate two loss functions containing first- and second-order geometric information of lesion regions to enforce regularization on optimizing deep segmentation models. Experimental results on two MS lesion datasets with different scales, acquisition protocols and resolutions demonstrated the superiority of our proposed methods compared to other state-of-the-art methods.

cs.CV↗

Efficient Folded Attention for 3D Medical Image Reconstruction and Segmentation

Recently, 3D medical image reconstruction (MIR) and segmentation (MIS) based on deep neural networks have been developed with promising results, and attention mechanism has been further designed to capture global contextual information for performance enhancement. However, the large size of 3D volume images poses a great computational challenge to traditional attention methods. In this paper, we propose a folded attention (FA) approach to improve the computational efficiency of traditional attention methods on 3D medical images. The main idea is that we apply tensor folding and unfolding operations with four permutations to build four small sub-affinity matrices to approximate the original affinity matrix. Through four consecutive sub-attention modules of FA, each element in the feature tensor can aggregate spatial-channel information from all other elements. Compared to traditional attention methods, with moderate improvement of accuracy, FA can substantially reduce the computational complexity and GPU memory consumption. We demonstrate the superiority of our method on two challenging tasks for 3D MIR and MIS, which are quantitative susceptibility mapping and multiple sclerosis lesion segmentation.

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Driving Conditions-Driven Energy Management for Hybrid Electric Vehicles: A Review

Motivated by the concerns on transported fuel consumption and global air pollution, industrial engineers, and academic researchers have made many efforts to construct more efficient and environment-friendly vehicles. Hybrid electric vehicles (HEVs) are the representative ones because they can satisfy the power demand by coordinating energy supplements among different energy storage devices. To achieve this goal, energy management approaches are crucial technology, and driving cycles are the critical influence factor. Therefore, this paper aims to summarize driving cycle-driven energy management strategies (EMSs) for HEVs. First, the definition and significance of driving cycles in the energy management field are clarified, and the recent literature in this research domain is reviewed and revisited. In addition, according to the known information of driving cycles, the EMSs are divided into three categories, and the relevant study directions, such as standard driving cycles, long-term driving cycle generation (LT-DCG) and short-term driving cycle prediction (ST-DCP) are illuminated and analyzed. Furthermore, the existing database of driving cycles in highway and urban aspects are displayed and discussed. Finally, this article also elaborates on the future prospects of energy management technologies related to driving cycles. This paper focusing on helping the relevant researchers realize the state-of-the-art of HEVs energy management field and also recognize its future development direction.

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Extending LOUPE for K-space Under-sampling Pattern Optimization in Multi-coil MRI

The previously established LOUPE (Learning-based Optimization of the Under-sampling Pattern) framework for optimizing the k-space sampling pattern in MRI was extended in three folds: firstly, fully sampled multi-coil k-space data from the scanner, rather than simulated k-space data from magnitude MR images in LOUPE, was retrospectively under-sampled to optimize the under-sampling pattern of in-vivo k-space data; secondly, binary stochastic k-space sampling, rather than approximate stochastic k-space sampling of LOUPE during training, was applied together with a straight-through (ST) estimator to estimate the gradient of the threshold operation in a neural network; thirdly, modified unrolled optimization network, rather than modified U-Net in LOUPE, was used as the reconstruction network in order to reconstruct multi-coil data properly and reduce the dependency on training data. Experimental results show that when dealing with the in-vivo k-space data, unrolled optimization network with binary under-sampling block and ST estimator had better reconstruction performance compared to the ones with either U-Net reconstruction network or approximate sampling pattern optimization network, and once trained, the learned optimal sampling pattern worked better than the hand-crafted variable density sampling pattern when deployed with other conventional reconstruction methods.

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Transfer Deep Reinforcement Learning-enabled Energy Management Strategy for Hybrid Tracked Vehicle

This paper proposes an adaptive energy management strategy for hybrid electric vehicles by combining deep reinforcement learning (DRL) and transfer learning (TL). This work aims to address the defect of DRL in tedious training time. First, an optimization control modeling of a hybrid tracked vehicle is built, wherein the elaborate powertrain components are introduced. Then, a bi-level control framework is constructed to derive the energy management strategies (EMSs). The upper-level is applying the particular deep deterministic policy gradient (DDPG) algorithms for EMS training at different speed intervals. The lower-level is employing the TL method to transform the pre-trained neural networks for a novel driving cycle. Finally, a series of experiments are executed to prove the effectiveness of the presented control framework. The optimality and adaptability of the formulated EMS are illuminated. The founded DRL and TL-enabled control policy is capable of enhancing energy efficiency and improving system performance.

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Reinforcement Learning-Enabled Decision-Making Strategies for a Vehicle-Cyber-Physical-System in Connected Environment

As a typical vehicle-cyber-physical-system (V-CPS), connected automated vehicles attracted more and more attention in recent years. This paper focuses on discussing the decision-making (DM) strategy for autonomous vehicles in a connected environment. First, the highway DM problem is formulated, wherein the vehicles can exchange information via wireless networking. Then, two classical reinforcement learning (RL) algorithms, Q-learning and Dyna, are leveraged to derive the DM strategies in a predefined driving scenario. Finally, the control performance of the derived DM policies in safety and efficiency is analyzed. Furthermore, the inherent differences of the RL algorithms are embodied and discussed in DM strategies.

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Bayesian Learning of Probabilistic Dipole Inversion for Quantitative Susceptibility Mapping

A learning-based posterior distribution estimation method, Probabilistic Dipole Inversion (PDI), is proposed to solve quantitative susceptibility mapping (QSM) inverse problem in MRI with uncertainty estimation. A deep convolutional neural network (CNN) is used to represent the multivariate Gaussian distribution as the approximated posterior distribution of susceptibility given the input measured field. In PDI, such CNN is firstly trained on healthy subjects dataset with labels by maximizing the posterior Gaussian distribution loss function as used in Bayesian deep learning. When tested on new dataset without any label, PDI updates the pre-trained network in an unsupervised fashion by minimizing the KL divergence between the approximated posterior distribution represented by CNN and the true posterior distribution given the likelihood distribution from known physical model and prior distribution. Based on our experiments, PDI provides additional uncertainty estimation compared to the conventional MAP approach, meanwhile addressing the potential discrepancy issue of CNN when test data deviates from training dataset.

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EM-GAN: Fast Stress Analysis for Multi-Segment Interconnect Using Generative Adversarial Networks

In this paper, we propose a fast transient hydrostatic stress analysis for electromigration (EM) failure assessment for multi-segment interconnects using generative adversarial networks (GANs). Our work leverages the image synthesis feature of GAN-based generative deep neural networks. The stress evaluation of multi-segment interconnects, modeled by partial differential equations, can be viewed as time-varying 2D-images-to-image problem where the input is the multi-segment interconnects topology with current densities and the output is the EM stress distribution in those wire segments at the given aging time. Based on this observation, we train conditional GAN model using the images of many self-generated multi-segment wires and wire current densities and aging time (as conditions) against the COMSOL simulation results. Different hyperparameters of GAN were studied and compared. The proposed algorithm, called {\it EM-GAN}, can quickly give accurate stress distribution of a general multi-segment wire tree for a given aging time, which is important for full-chip fast EM failure assessment. Our experimental results show that the EM-GAN shows 6.6\% averaged error compared to COMSOL simulation results with orders of magnitude speedup. It also delivers 8.3X speedup over state-of-the-art analytic based EM analysis solver.

cs.LG↗

RSANet: Recurrent Slice-wise Attention Network for Multiple Sclerosis Lesion Segmentation

Brain lesion volume measured on T2 weighted MRI images is a clinically important disease marker in multiple sclerosis (MS). Manual delineation of MS lesions is a time-consuming and highly operator-dependent task, which is influenced by lesion size, shape and conspicuity. Recently, automated lesion segmentation algorithms based on deep neural networks have been developed with promising results. In this paper, we propose a novel recurrent slice-wise attention network (RSANet), which models 3D MRI images as sequences of slices and captures long-range dependencies through a recurrent manner to utilize contextual information of MS lesions. Experiments on a dataset with 43 patients show that the proposed method outperforms the state-of-the-art approaches. Our implementation is available online at https://github.com/tinymilky/RSANet.

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