arXiv subjects

Jiuchen Zhang

Publications and source records attributed to Jiuchen Zhang.

3 recordsLinked to original sources

arXiv2026

Neural Network Machine Regression (NNMR): A Deep Learning Framework for Uncovering High-order Synergistic Effects

We propose a new neural network framework, termed Neural Network Machine Regression (NNMR), which integrates trainable input gating and adaptive depth regularization to jointly perform feature selection and function estimation in an end-to-end manner. By penalizing both gating parameters and redundant layers, NNMR yields sparse and interpretable architectures while capturing complex nonlinear relationships driven by high-order synergistic effects. We further develop a post-selection inference procedure based on split-sample, permutation-based hypothesis testing, enabling valid inference without restrictive parametric assumptions. Compared with existing methods, including Bayesian kernel machine regression and widely used post hoc attribution techniques, NNMR scales efficiently to high-dimensional feature spaces while rigorously controlling type I error. Simulation studies demonstrate its superior selection accuracy and inference reliability. Finally, an empirical application reveals sparse, biologically meaningful food group predictors associated with somatic growth among adolescents living in Mexico City.

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arXiv2026

Cumulative Treatment Effect Testing under Continuous Time Reinforcement Learning

Understanding the impact of treatment effect over time is a fundamental aspect of many scientific and medical studies. In this paper, we introduce a novel approach under a continuous-time reinforcement learning framework for testing a treatment effect. Specifically, our method provides an effective test on carryover effects of treatment over time utilizing the average treatment effect (ATE). The average treatment effect is defined as difference of value functions over an infinite horizon, which accounts for cumulative treatment effects, both immediate and carryover. The proposed method outperforms existing testing procedures such as discrete time reinforcement learning strategies in multi-resolution observation settings where observation times can be irregular. Another advantage of the proposed method is that it can capture treatment effects of a shorter duration and provide greater accuracy compared to discrete-time approximations, through the use of continuous-time estimation for the value function. We establish the asymptotic normality of the proposed test statistics and apply it to OhioT1DM diabetes data to evaluate the cumulative treatment effects of bolus insulin on patients' glucose levels.

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arXiv2024

Individualized Dynamic Latent Factor Model for Multi-resolutional Data with Application to Mobile Health

Mobile health has emerged as a major success for tracking individual health status, due to the popularity and power of smartphones and wearable devices. This has also brought great challenges in handling heterogeneous, multi-resolution data which arise ubiquitously in mobile health due to irregular multivariate measurements collected from individuals. In this paper, we propose an individualized dynamic latent factor model for irregular multi-resolution time series data to interpolate unsampled measurements of time series with low resolution. One major advantage of the proposed method is the capability to integrate multiple irregular time series and multiple subjects by mapping the multi-resolution data to the latent space. In addition, the proposed individualized dynamic latent factor model is applicable to capturing heterogeneous longitudinal information through individualized dynamic latent factors. Our theory provides a bound on the integrated interpolation error and the convergence rate for B-spline approximation methods. Both the simulation studies and the application to smartwatch data demonstrate the superior performance of the proposed method compared to existing methods.

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