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Jiwei Zhao

Publications and source records attributed to Jiwei Zhao.

34 records · Page 2Linked to original sources

Assumption-Lean and Data-Adaptive Post-Prediction Inference

A primary challenge facing modern scientific research is the limited availability of gold-standard data which can be costly, labor-intensive, or invasive to obtain. With the rapid development of machine learning (ML), scientists can now employ ML algorithms to predict gold-standard outcomes with variables that are easier to obtain. However, these predicted outcomes are often used directly in subsequent statistical analyses, ignoring imprecision and heterogeneity introduced by the prediction procedure. This will likely result in false positive findings and invalid scientific conclusions. In this work, we introduce PoSt-Prediction Adaptive inference (PSPA) that allows valid and powerful inference based on ML-predicted data. Its "assumption-lean" property guarantees reliable statistical inference without assumptions on the ML prediction. Its "data-adaptive" feature guarantees an efficiency gain over existing methods, regardless of the accuracy of ML prediction. We demonstrate the statistical superiority and broad applicability of our method through simulations and real-data applications.

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Coverage Analysis of Downlink Transmission in Multi-Connectivity Cellular V2X Networks

With the increasing of connected vehicles in the fifth-generation mobile communication networks (5G) and beyond 5G (B5G), ensuring the reliable and high-speed cellular vehicle-to-everything (C-V2X) communication has posed significant challenges due to the high mobility of vehicles. For improving the network performance and reliability, multi-connectivity technology has emerged as a crucial transmission mode for C-V2X in the 5G era. To this end, this paper proposes a framework for analyzing the performance of multi-connectivity in C-V2X downlink transmission, with a focus on the performance indicators of joint distance distribution and coverage probability. Specifically, we first derive the joint distance distribution of multi-connectivity. By leveraging the tools of stochastic geometry, we then obtain the analytical expressions of coverage probability based on the previous results for general multi-connectivity cases in C-V2X. Subsequently, we evaluate the effect of path loss exponent and downlink base station density on coverage probability based on the proposed analytical framework. Finally, extensive Monte Carlo simulations are conducted to validate the effectiveness of the proposed analytical framework and the simulation results reveal that multi-connectivity technology can significantly enhance the coverage probability in C-V2X.

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Performance Analysis for Downlink Transmission in Multi-Connectivity Cellular V2X Networks

With the ever-increasing number of connected vehicles in the fifth-generation mobile communication networks (5G) and beyond 5G (B5G), ensuring the reliability and high-speed demand of cellular vehicle-to-everything (C-V2X) communication in scenarios where vehicles are moving at high speeds poses a significant challenge.Recently, multi-connectivity technology has become a promising network access paradigm for improving network performance and reliability for C-V2X in the 5G and B5G era. To this end, this paper proposes an analytical framework for the performance of downlink in multi-connectivity C-V2X networks. Specifically, by modeling the vehicles and base stations as one-dimensional Poisson point processes, we first derive and analyze the joint distance distribution of multi-connectivity. Then through leveraging the tools of stochastic geometry, the coverage probability and spectral efficiency are obtained based on the previous results for general multi-connectivity cases in C-V2X. Additionally, we evaluate the effect of path loss exponent and the density of downlink base station on system performance indicators. We demonstrate through extensive Monte Carlo simulations that multi-connectivity technology can effectively enhance network performance in C-V2X. Our findings have important implications for the research and application of multi-connectivity C-V2X in the 5G and B5G era.

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Channel-Feedback-Free Transmission for Downlink FD-RAN: A Radio Map based Complex-valued Precoding Network Approach

As the demand for high-quality services proliferates, an innovative network architecture, the fully-decoupled RAN (FD-RAN), has emerged for more flexible spectrum resource utilization and lower network costs. However, with the decoupling of uplink base stations and downlink base stations in FD-RAN, the traditional transmission mechanism, which relies on real-time channel feedback, is not suitable as the receiver is not able to feedback accurate and timely channel state information to the transmitter. This paper proposes a novel transmission scheme without relying on physical layer channel feedback. Specifically, we design a radio map based complex-valued precoding network~(RMCPNet) model, which outputs the base station precoding based on user location. RMCPNet comprises multiple subnets, with each subnet responsible for extracting unique modal features from diverse input modalities. Furthermore, the multi-modal embeddings derived from these distinct subnets are integrated within the information fusion layer, culminating in a unified representation. We also develop a specific RMCPNet training algorithm that employs the negative spectral efficiency as the loss function. We evaluate the performance of the proposed scheme on the public DeepMIMO dataset and show that RMCPNet can achieve 16\% and 76\% performance improvements over the conventional real-valued neural network and statistical codebook approach, respectively.

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Efficient and Model-Agnostic Parameter Estimation Under Privacy-Preserving Post-randomization Data

Protecting individual privacy is crucial when releasing sensitive data for public use. While data de-identification helps, it is not enough. This paper addresses parameter estimation in scenarios where data are perturbed using the Post-Randomization Method (PRAM) to enhance privacy. Existing methods for parameter estimation under PRAM data suffer from limitations like being parameter-specific, model-dependent, and lacking efficiency guarantees. We propose a novel, efficient method that overcomes these limitations. Our method is applicable to general parameters defined through estimating equations and makes no assumptions about the underlying data model. We further prove that the proposed estimator achieves the semiparametric efficiency bound, making it optimal in terms of asymptotic variance.

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ReTaSA: A Nonparametric Functional Estimation Approach for Addressing Continuous Target Shift

The presence of distribution shifts poses a significant challenge for deploying modern machine learning models in real-world applications. This work focuses on the target shift problem in a regression setting (Zhang et al., 2013; Nguyen et al., 2016). More specifically, the target variable y (also known as the response variable), which is continuous, has different marginal distributions in the training source and testing domain, while the conditional distribution of features x given y remains the same. While most literature focuses on classification tasks with finite target space, the regression problem has an infinite dimensional target space, which makes many of the existing methods inapplicable. In this work, we show that the continuous target shift problem can be addressed by estimating the importance weight function from an ill-posed integral equation. We propose a nonparametric regularized approach named ReTaSA to solve the ill-posed integral equation and provide theoretical justification for the estimated importance weight function. The effectiveness of the proposed method has been demonstrated with extensive numerical studies on synthetic and real-world datasets.

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Doubly Flexible Estimation under Label Shift

In studies ranging from clinical medicine to policy research, complete data are usually available from a population $\mathscr{P}$, but the quantity of interest is often sought for a related but different population $\mathscr{Q}$ which only has partial data. In this paper, we consider the setting that both outcome $Y$ and covariate ${\bf X}$ are available from $\mathscr{P}$ whereas only ${\bf X}$ is available from $\mathscr{Q}$, under the so-called label shift assumption, i.e., the conditional distribution of ${\bf X}$ given $Y$ remains the same across the two populations. To estimate the parameter of interest in $\mathscr{Q}$ via leveraging the information from $\mathscr{P}$, the following three ingredients are essential: (a) the common conditional distribution of ${\bf X}$ given $Y$, (b) the regression model of $Y$ given ${\bf X}$ in $\mathscr{P}$, and (c) the density ratio of $Y$ between the two populations. We propose an estimation procedure that only needs standard nonparametric technique to approximate the conditional expectations with respect to (a), while by no means needs an estimate or model for (b) or (c); i.e., doubly flexible to the possible model misspecifications of both (b) and (c). This is conceptually different from the well-known doubly robust estimation in that, double robustness allows at most one model to be misspecified whereas our proposal can allow both (b) and (c) to be misspecified. This is of particular interest in our setting because estimating (c) is difficult, if not impossible, by virtue of the absence of the $Y$-data in $\mathscr{Q}$. Furthermore, even though the estimation of (b) is sometimes off-the-shelf, it can face curse of dimensionality or computational challenges. We develop the large sample theory for the proposed estimator, and examine its finite-sample performance through simulation studies as well as an application to the MIMIC-III database.

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Sufficient Identification Conditions and Semiparametric Estimation under Missing Not at Random Mechanisms

Conducting valid statistical analyses is challenging in the presence of missing-not-at-random (MNAR) data, where the missingness mechanism is dependent on the missing values themselves even conditioned on the observed data. Here, we consider a MNAR model that generalizes several prior popular MNAR models in two ways: first, it is less restrictive in terms of statistical independence assumptions imposed on the underlying joint data distribution, and second, it allows for all variables in the observed sample to have missing values. This MNAR model corresponds to a so-called criss-cross structure considered in the literature on graphical models of missing data that prevents nonparametric identification of the entire missing data model. Nonetheless, part of the complete-data distribution remains nonparametrically identifiable. By exploiting this fact and considering a rich class of exponential family distributions, we establish sufficient conditions for identification of the complete-data distribution as well as the entire missingness mechanism. We then propose methods for testing the independence restrictions encoded in such models using odds ratio as our parameter of interest. We adopt two semiparametric approaches for estimating the odds ratio parameter and establish the corresponding asymptotic theories: one involves maximizing a conditional likelihood with order statistics and the other uses estimating equations. The utility of our methods is illustrated via simulation studies.

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ELSA: Efficient Label Shift Adaptation through the Lens of Semiparametric Models

We study the domain adaptation problem with label shift in this work. Under the label shift context, the marginal distribution of the label varies across the training and testing datasets, while the conditional distribution of features given the label is the same. Traditional label shift adaptation methods either suffer from large estimation errors or require cumbersome post-prediction calibrations. To address these issues, we first propose a moment-matching framework for adapting the label shift based on the geometry of the influence function. Under such a framework, we propose a novel method named \underline{E}fficient \underline{L}abel \underline{S}hift \underline{A}daptation (ELSA), in which the adaptation weights can be estimated by solving linear systems. Theoretically, the ELSA estimator is $\sqrt{n}$-consistent ($n$ is the sample size of the source data) and asymptotically normal. Empirically, we show that ELSA can achieve state-of-the-art estimation performances without post-prediction calibrations, thus, gaining computational efficiency.

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Test of Significance for High-dimensional Thresholds with Application to Individualized Minimal Clinically Important Difference

This work is motivated by learning the individualized minimal clinically important difference, a vital concept to assess clinical importance in various biomedical studies. We formulate the scientific question into a high-dimensional statistical problem where the parameter of interest lies in an individualized linear threshold. The goal is to develop a hypothesis testing procedure for the significance of a single element in this parameter as well as of a linear combination of this parameter. The difficulty dues to the high-dimensional nuisance in developing such a testing procedure, and also stems from the fact that this high-dimensional threshold model is nonregular and the limiting distribution of the corresponding estimator is nonstandard. To deal with these challenges, we construct a test statistic via a new bias-corrected smoothed decorrelated score approach, and establish its asymptotic distributions under both null and local alternative hypotheses. We propose a double-smoothing approach to select the optimal bandwidth in our test statistic and provide theoretical guarantees for the selected bandwidth. We conduct simulation studies to demonstrate how our proposed procedure can be applied in empirical studies. We apply the proposed method to a clinical trial where the scientific goal is to assess the clinical importance of a surgery procedure.

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Optimal and Safe Estimation for High-Dimensional Semi-Supervised Learning

We consider the estimation problem in high-dimensional semi-supervised learning. Our goal is to investigate when and how the unlabeled data can be exploited to improve the estimation of the regression parameters of linear model in light of the fact that such linear models may be misspecified in data analysis. We first establish the minimax lower bound for parameter estimation in the semi-supervised setting, and show that this lower bound cannot be achieved by supervised estimators using the labeled data only. We propose an optimal semi-supervised estimator that can attain this lower bound and therefore improves the supervised estimators, provided that the conditional mean function can be consistently estimated with a proper rate. We further propose a safe semi-supervised estimator. We view it safe, because this estimator is always at least as good as the supervised estimators. We also extend our idea to the aggregation of multiple semi-supervised estimators caused by different misspecifications of the conditional mean function. Extensive numerical simulations and a real data analysis are conducted to illustrate our theoretical results.

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A Statistical Inference Framework for the Minimal Clinically Important Difference

In clinical research, the effect of a treatment or intervention is widely assessed through clinical importance, instead of statistical significance. In this paper, we propose a principled statistical inference framework to learning the minimal clinically important difference (MCID), a vital concept in assessing clinical importance. We formulate the scientific question into a novel statistical learning problem, develop an efficient algorithm for parameter estimation, and establish the asymptotic theory for the proposed estimator. We conduct comprehensive simulation studies to examine the finite sample performance of the proposed method. We also re-analyze the ChAMP (Chondral Lesions And Meniscus Procedures) trial, where the primary outcome is the patient-reported pain score and the ultimate goal is to determine whether there exists a significant difference in post-operative knee pain between patients undergoing debridement versus observation of chondral lesions during the surgery. Some previous analysis of this trial exhibited that the effect of debriding the chondral lesions does not reach a statistical significance. Our analysis reinforces this conclusion that the effect of debriding the chondral lesions is not only statistically non-significant, but also clinically un-important.

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Avoid Estimating the Unknown Function in a Semiparametric Nonignorable Propensity Model

We study the problem of estimating a functional or a parameter in the context where outcome is subject to nonignorable missingness. We completely avoid modeling the regression relation, while allowing the propensity to be modeled by a semiparametric logistic relation where the dependence on covariates is unspecified. We discover a surprising phenomenon in that the estimation of the parameter in the propensity model as well as the functional estimation can be carried out without assessing the missingness dependence on covariates. This allows us to propose a general class of estimators for both model parameter estimation and functional estimation, including estimating the outcome mean. The robustness of the estimators are nonstandard and are established rigorously through theoretical derivations, and are supported by simulations and a data application.

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A Versatile Estimation Procedure without Estimating the Nonignorable Missingness Mechanism

We consider the estimation problem in a regression setting where the outcome variable is subject to nonignorable missingness and identifiability is ensured by the shadow variable approach. We propose a versatile estimation procedure where modeling of missingness mechanism is completely bypassed. We show that our estimator is easy to implement and we derive the asymptotic theory of the proposed estimator. We also investigate some alternative estimators under different scenarios. Comprehensive simulation studies are conducted to demonstrate the finite sample performance of the method. We apply the estimator to a children's mental health study to illustrate its usefulness.

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Nonregular and Minimax Estimation of Individualized Thresholds in High Dimension with Binary Responses

Given a large number of covariates $Z$, we consider the estimation of a high-dimensional parameter $θ$ in an individualized linear threshold $θ^T Z$ for a continuous variable $X$, which minimizes the disagreement between $\text{sign}(X-θ^TZ)$ and a binary response $Y$. While the problem can be formulated into the M-estimation framework, minimizing the corresponding empirical risk function is computationally intractable due to discontinuity of the sign function. Moreover, estimating $θ$ even in the fixed-dimensional setting is known as a nonregular problem leading to nonstandard asymptotic theory. To tackle the computational and theoretical challenges in the estimation of the high-dimensional parameter $θ$, we propose an empirical risk minimization approach based on a regularized smoothed loss function. The statistical and computational trade-off of the algorithm is investigated. Statistically, we show that the finite sample error bound for estimating $θ$ in $\ell_2$ norm is $(s\log d/n)^{β/(2β+1)}$, where $d$ is the dimension of $θ$, $s$ is the sparsity level, $n$ is the sample size and $β$ is the smoothness of the conditional density of $X$ given the response $Y$ and the covariates $Z$. The convergence rate is nonstandard and slower than that in the classical Lasso problems. Furthermore, we prove that the resulting estimator is minimax rate optimal up to a logarithmic factor. The Lepski's method is developed to achieve the adaption to the unknown sparsity $s$ and smoothness $β$. Computationally, an efficient path-following algorithm is proposed to compute the solution path. We show that this algorithm achieves geometric rate of convergence for computing the whole path. Finally, we evaluate the finite sample performance of the proposed estimator in simulation studies and a real data analysis.

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Penalized pairwise pseudo likelihood for variable selection with nonignorable missing data

The regularization approach for variable selection was well developed for a completely observed data set in the past two decades. In the presence of missing values, this approach needs to be tailored to different missing data mechanisms. In this paper, we focus on a flexible and generally applicable missing data mechanism, which contains both ignorable and nonignorable missing data mechanism assumptions. We show how the regularization approach for variable selection can be adapted to the situation under this missing data mechanism. The computational and theoretical properties for variable selection consistency are established. The proposed method is further illustrated by comprehensive simulation studies and real data analyses, for both low and high dimensional settings.

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