arXiv subjects

John Regan

Publications and source records attributed to John Regan.

At least 19 recordsLinked to original sources

arXiv2026

Measuring the Occupation-Level Impact of AbbVie Intelligence: AI Applicability Analysis, 2024-2025

This paper presents an empirical analysis of AbbVie Intelligence's measurable impact on employee work activities across 192 distinct occupations in 2024 and 2025. Drawing on 598,744 de-identified AI conversations classified according to the O*NET Intermediate Work Activity (IWA) taxonomy, we compute occupation-level AI Applicability Scores that quantify the extent to which AI tools can meaningfully assist or automate real work at scale. Three convergent analyses are conducted: (1) longitudinal year-over-year trends from 2024 to 2025, (2) a quasi-experimental pre-post evaluation of the AbbVie Intelligence version 3 platform release in August 2025, and (3) a pre-post evaluation of the AbbVie AI Learning Summit held in November 22025. Results demonstrate statistically significant improvements across all three dimensions. Mean AI Applicability Scores rose substantially from 2024 to 2025; the platform release product a +10.0% gain (p<0.001); and the AI Learning Summit produced a +6.68% gain (p<0.001). These findings establish that both technological platform enhancements and structured enterprise AI eduction programs independently and substantially expand the reach of AI across the AbbVie workforce.

cs.CY↗

arXiv2026

The LISA Astrophysics MBHcatalogues Project: A comparison of predictions of simulated massive black hole binaries

In the hierarchical paradigm of galaxy formation, central massive black holes (MBHs) are expected to coalesce after the merger of their host galaxies. One of the main goals of the Laser Interferometer Space Antenna (LISA) is to constrain the origin and growth of MBHs through their merger rates and mass distribution. Predicting MBH merger rates requires not only tracing their statistical population from large to small physical scales (kpc to sub-pc) but also modelling their formation, accretion, dynamics, mergers, and their galactic physical processes across cosmic time. This project is the result of a large collaborative effort undertaken by the LISA Astrophysics Working Group, bringing together its collective expertise on MBH formation, evolution, and modelling, to build a comprehensive understanding of MBH merger rates across cosmic time. The project compares various theoretical predictions of MBH merger rates, quantifies the spread, and evaluates the global astrophysical uncertainties of the LISA event rates. To build a unique and complete view, our work is based on about 20 semi-analytical models and cosmological simulations from the literature, all employing distinct approaches to modelling MBH and galaxy physics. To compute the merger rates, we also incorporate delays arising from the dynamical phase of MBH hardening to coalescence. We present the expected LISA merger rates given current galaxy formation models and discuss how the merger rate depends on model assumptions, such as the seeding model and the resolution of cosmological simulations.

astro-ph.GA↗

arXiv2025

Rotating Supermassive Pop III Stars On The Main Sequence

The detection of billion-solar-mass supermassive black holes (SMBHs) within the first billion years of cosmic history challenges conventional theories of black hole formation and growth. Simultaneously, recent JWST observations revealing exceptionally high nitrogen-to-oxygen abundance ratios in galaxies at high redshifts raise critical questions about rapid chemical enrichment mechanisms operating in the early universe. Supermassive stars (SMSs) with masses of 1000 to 10000 M$_{\odot}$ are promising candidates to explain these phenomena, but existing models have so far neglected the pivotal role of stellar rotation. Here, we present the first comprehensive evolutionary models of rotating Pop III SMSs computed using the GENEC stellar evolution code, including detailed treatments of rotation-induced chemical mixing, angular momentum transport, and mass loss driven by the $\Omega\Gamma$ limit. We demonstrate that rotation significantly enlarges the convective core and extends stellar lifetimes by up to 20%, with moderate enhancement of mass-loss rates as stars approach critical rotation thresholds. Our results further indicate that the cores of SMSs rotate relatively slowly (below $\sim 200$ km s$^{-1}$), resulting in dimensionless spin parameters $a* < 0.1$ for intermediate-mass black hole (IMBH) remnants that are notably lower than theoretical maximum spins. These findings highlight rotation as a key factor in determining the structural evolution, chemical yields, and black hole spin properties of SMSs, providing critical insights to interpret observational signatures from the high-redshift universe.

astro-ph.SR↗

arXiv2025

On the Use of WGANs for Super-Resolution in Dark-Matter Simulations

Super-resolution techniques have the potential to reduce the computational cost of cosmological and astrophysical simulations. This can be achieved by enabling traditional simulation methods to run at lower resolution and then efficiently computing high-resolution data corresponding to the simulated low-resolution data. In this work, we investigate the application of a Wasserstein Generative Adversarial Network (WGAN) model, previously proposed in the literature, to increase the particle resolution of dark-matter-only simulations. We reproduce prior results, showing the WGAN model successfully generates high-resolution data with summary statistics, including the power spectrum and halo mass function, that closely match those of true high-resolution simulations. However, we also identify a limitation of the WGAN model in the form of smeared features in generated high-resolution data, particularly in the shapes of dark-matter halos and filaments. This limitation points to a potential weakness of the proposed WGAN-based super-resolution method in capturing the detailed structure of halos, and underscores the need for further development in applying such models to cosmological data.

astro-ph.GA↗

arXiv2024

A Heavy Seed Black Hole Mass Function at High Redshift -- Prospects for LISA

The advent of new and near-future observatories probing the earliest epochs of the Universe has opened the opportunity to investigate the formation and growth of the first massive black holes (MBHs). Additionally, the use of high resolution cosmological simulations to investigate these high-redshift environments is needed to predict the dark matter halos in which these MBH seeds will form. We use the Renaissance simulations to analyse the formation and growth of so-called heavy seed black holes. Other past work has investigated the formation and growth of light (black hole) seeds with Renaissance and found that these black holes do not grow in the environments in which they reside. In this work we seed MBHs, in post-processing, and track accretion onto the MBHs as well as mergers with other MBHs at high-redshift. We show that the heavy seeds struggle to achieve high accretion rates with only the most massive black holes ($\gtrsim 10^5 M_{\odot}$) growing at close to the Eddington limit under optimistic conditions. Despite the lack of significant growth for these early MBHs, the signals from their merger events will be sufficiently strong (SNR $\sim 10^2$) to be probed by the next generation of gravitational wave observatories, such as LISA. We predict that LISA will observe of the order of 10 MBH merger events per year where the mergers occur at z $\gtrsim$ 10 or at least begin their early inspiral phase at z $\gtrsim$ 10.

astro-ph.GA↗

arXiv2024

Massive Black Hole Seeds

The pathway(s) to seeding the massive black holes (MBHs) that exist at the heart of galaxies in the present and distant Universe remains an unsolved problem. Here we categorise, describe and quantitatively discuss the formation pathways of both $\textit{light}$ and $\textit{heavy}$ seeds. We emphasise that the most recent computational models suggest that rather than a bimodal-like mass spectrum between $\textit{light}$ and $\textit{heavy}$ seeds with $\textit{light}$ at one end and $\textit{heavy}$ at the other that instead a continuum exists. $\textit{Light}$ seeds being more ubiquitous and the heavier seeds becoming less and less abundant due the rarer environmental conditions required for their formation. We therefore examine the different mechanisms that give rise to different seed mass spectrums. We show how and why the mechanisms that produce the $\textit{heaviest}$ seeds are also among the rarest events in the Universe and are hence extremely unlikely to be the seeds for the vast majority of the MBH population. We quantify, within the limits of the current large uncertainties in the seeding processes, the expected number densities of the seed mass spectrum. We argue that $\textit{light}$ seeds must be at least $10^{3}$ to $10^{5}$ times more numerous than $\textit{heavy}$ seeds to explain the MBH population as a whole. Based on our current understanding of the seed population this makes $\textit{heavy}$ seeds ($\rm{M_{seed}} > 10^3$ M$_{\odot}$) a significantly more likely pathway given that $\textit{heavy}$ seeds have an abundance pattern than is close to and likely in excess of $10^{-4}$ compared to $\textit{light}$ seeds. Finally, we examine the current state-of-the-art in numerical calculations and recent observations and plot a path forward for near-future advances in both domains.

astro-ph.GA↗

arXiv2023

Massive Black Holes in Galactic Nuclei

Massive black holes are key inhabitants of the nuclei of galaxies. Moreover, their astrophysical relevance has gained significant traction in recent years, thanks especially to the amazing results that are being (or will be) delivered by instruments such as the James Webb Space Telescope, Pulsar Timing Array projects and LISA. In this Chapter, we aim to detail a broad set of aspects related to the astrophysical nature of massive black holes embedded in galactic nuclei, with a particular focus on recent and upcoming advances in the field. In particular, we will address questions such as: What shapes the relations connecting the mass of massive black holes with the properties of their host galaxies? How do massive black holes form in the early Universe? What mechanisms keep on feeding them so that they can attain very large masses at z = 0? How do binaries composed of two massive black holes form and coalesce into a single, larger black hole? Here we present these topics from a mainly theoretical viewpoint and discuss how present and upcoming facilities may enhance our understanding of massive black holes in the near future.

astro-ph.GA↗

arXiv2023

No Tension: JWST Galaxies at $z > 10$ Consistent with Cosmological Simulations

Recent observations by JWST have uncovered galaxies in the very early universe via the JADES and CEERS surveys. These galaxies have been measured to have very high stellar masses with substantial star formation rates. There are concerns that these observations are in tension with the $Λ$CDM model of the universe, as the stellar masses of the galaxies are relatively high for their respective redshifts. Recent studies have compared the JWST observations with large-scale cosmological simulations. While they were successful in reproducing the galaxies seen in JADES and CEERS, the mass and spatial resolution of these simulations were insufficient to fully capture the early assembly history of the simulated galaxies. In this study, we use results from the Renaissance simulations, which are a suite of high resolution simulations designed to model galaxy formation in the early universe. We find that the most massive galaxies in Renaissance have stellar masses and star formation rates that are entirely consistent with the observations from the JADES and CEERS surveys. The exquisite resolution afforded by Renaissance allows us to model the build-up of early galaxies from stellar masses as low as 10$^4$ M$_\odot$ up to a maximum stellar mass of a few times 10$^{7}$ M$_\odot$. Within this galaxy formation paradigm, we find excellent agreement with JADES and CEERS. We find no tension between the $Λ$CDM model and current JWST measurements. As JWST continues to explore the high redshift universe, high resolution simulations, such as Renaissance, will continue to be crucial in understanding the formation history of early embryonic galaxies.

astro-ph.GA↗

arXiv2023

Astrophysics with the Laser Interferometer Space Antenna

The Laser Interferometer Space Antenna (LISA) will be a transformative experiment for gravitational wave astronomy, and, as such, it will offer unique opportunities to address many key astrophysical questions in a completely novel way. The synergy with ground-based and space-born instruments in the electromagnetic domain, by enabling multi-messenger observations, will add further to the discovery potential of LISA. The next decade is crucial to prepare the astrophysical community for LISA's first observations. This review outlines the extensive landscape of astrophysical theory, numerical simulations, and astronomical observations that are instrumental for modeling and interpreting the upcoming LISA datastream. To this aim, the current knowledge in three main source classes for LISA is reviewed; ultracompact stellar-mass binaries, massive black hole binaries, and extreme or intermediate mass ratio inspirals. The relevant astrophysical processes and the established modeling techniques are summarized. Likewise, open issues and gaps in our understanding of these sources are highlighted, along with an indication of how LISA could help making progress in the different areas. New research avenues that LISA itself, or its joint exploitation with upcoming studies in the electromagnetic domain, will enable, are also illustrated. Improvements in modeling and analysis approaches, such as the combination of numerical simulations and modern data science techniques, are discussed. This review is intended to be a starting point for using LISA as a new discovery tool for understanding our Universe.

gr-qc↗

arXiv2022

Massive Star Formation in Overdense Regions of the Early Universe

Both the origin of, and the population demographics of, massive black holes (MBHs) remains an open question in modern day astrophysics. Here we introduce the BlackDemon suite of cosmological simulations using the Enzo code. The suite consists primarily of three, high resolution, distinct regions, each with a side length of 1 h$^{-1}$ Mpc. Two of the regions evolve within a larger overdense region while the other evolves within a more `normal' region. The simulation suite has spatial and mass resolution capable of resolving the formation of the first galaxies and MBHs within each region. We report here, as the first in a series of papers, the evolution of the simulation suite up to the point where star formation has commenced in each region and for 2 Myr after the onset of star formation. Within these environments the masses of the first objects to form have masses between approximately 100 M$_{\odot}$ and $10^4$ M$_{\odot}$. The larger mass objects form due to both major mergers, which trigger rapid mass inflow to the centre of the halo, and also through multiple minor mergers which allows the host halo to grow to close to the atomic cooling threshold. In both scenarios the initially very high accretion rates quickly grow the objects to close to $10^4$ M$_{\odot}$. However, accretion halts after less than 50,000 years due to gas starvation. The final fate of these objects in terms of fragmentation and subsequent fragment mergers cannot be deduced at our current resolution. In the case where fragmentation is mild such objects are likely to form super-massive stars before contracting to the main sequence evolving into massive population III stars and subsequently MBHs.

astro-ph.GA↗

arXiv2019

Unveiling the Gravitational Universe at μ-Hz Frequencies

We propose a space-based interferometer surveying the gravitational wave (GW) sky in the milli-Hz to $μ$-Hz frequency range. By the 2040s', the $μ$-Hz frequency band, bracketed in between the Laser Interferometer Space Antenna (LISA) and pulsar timing arrays, will constitute the largest gap in the coverage of the astrophysically relevant GW spectrum. Yet many outstanding questions related to astrophysics and cosmology are best answered by GW observations in this band. We show that a $μ$-Hz GW detector will be a truly overarching observatory for the scientific community at large, greatly extending the potential of LISA. Conceived to detect massive black hole binaries from their early inspiral with high signal-to-noise ratio, and low-frequency stellar binaries in the Galaxy, this instrument will be a cornerstone for multimessenger astronomy from the solar neighbourhood to the high-redshift Universe.

astro-ph.IM↗

arXiv2019

Electromagnetic Window into the Dawn of Black Holes

Massive 10^6-10^10 Msun black holes (BHs) are ubiquitous in local galactic nuclei. They were common by the time the Universe is several Gyr old, and many of them were in place within the first 1~Gyr after the Big Bang. Their quick assembly has been attributed to mechanisms such as the rapid collapse of gas into the nuclei of early protogalaxies, accretion and mergers of stellar-mass BHs accompanying structure formation at early times, and the runaway collapse of early, ultra-dense stellar clusters. The origin of the early massive BHs remains an intriguing and long-standing unsolved puzzle in astrophysics. Here we discuss strategies for discerning between BH seeding models using electromagnetic observations. We argue that the most direct answers will be obtained through detection of BHs with masses M<10^5 Msun at redshifts z>10, where we expect them to first form. Reaching out to these redshifts and down to these masses is crucial, because BHs are expected to lose the memory of their initial assembly by the time they grow well above 10^5 Msun and are incorporated into higher-mass galaxies. The best way to detect 10^4-10^5 Msun BHs at high redshifts is by a sensitive X-ray survey. Critical constraining power is augmented by establishing the properties and the environments of their host galaxies in deep optical/IR imaging surveys. Required OIR data can be obtained with the JWST and WFIRST missions. The required X-ray flux limits (down to 10^{-19} erg/s/cm^2) are accessible only with a next-generation X-ray observatory which has both high (sub-1") angular resolution and high throughput. A combination of deep X-ray and OIR surveys will be capable of probing several generic markers of the BH seed scenarios, and resolving the long-stanging puzzle of their origin. These electromagnetic observations are also highly synergistic with the information from LISA on high-z BH mergers.

astro-ph.HE↗

arXiv2018

The Growth of Black Holes from Population III Remnants in the Renaissance Simulations

The formation of stellar mass black holes from the remnants of Population III stars provides a source of initial black hole seeds with the potential to grow into intermediate or, in rare cases, possibly supermassive black holes. We use the Renaissance simulation suite to follow the growth of over 15,000 black holes born into mini-haloes in the early Universe. We compute the evolution of the black holes by post-processing individual remnant Population III star particles in the Renaissance simulation snapshots. The black holes populate haloes from 10$^{6}$ M$_{\odot}$ up to 10$^{9}$ M$_{\odot}$. We find that all of the black holes display very inefficient growth. On average the black holes increase their initial mass by a factor 10$^{-5}$, with the most active black holes increasing their mass by approximately 10%. Only a single black hole experiences any period of super-Eddington accretion, but the duration is very short and not repeated. Furthermore, we find no correlation of black hole accretion with halo mass in the mass range sampled. Within most haloes, we identify clumps of cool, dense gas for which accretion rates would be high, but instances of black holes encountering these clumps are rare and short-lived. Star formation competes with black hole growth by consuming available gas and driving down accretion rates through feedback. We conclude that the black holes born from Population III remnants do not form a significant population of intermediate mass black holes in the early Universe and will need to wait until later times to undergo significant accretion, if at all.

astro-ph.GA↗

arXiv2017

The formation of direct collapse black holes under the influence of streaming velocities

We study the influence of a high baryonic streaming velocity on the formation of direct collapse black holes (DCBHs) with the help of cosmological simulations carried out using the moving mesh code {\sc arepo}. We show that a streaming velocity that is as large as three times the root-mean-squared value is effective at suppressing the formation of H$_{2}$-cooled minihaloes, while still allowing larger atomic cooling haloes (ACHs) to form. We find that enough H$_{2}$ forms in the centre of these ACHs to effectively cool the gas, demonstrating that a high streaming velocity by itself cannot produce the conditions required for DCBH formation. However, we argue that high streaming velocity regions do provide an ideal environment for the formation of DCBHs in close pairs of ACHs (the "synchronised halo" model). Due to the absence of star formation in minihaloes, the gas remains chemically pristine until the ACHs form. If two such haloes form with only a small separation in time and space, then the one forming stars earlier can provide enough ultraviolet radiation to suppress H$_{2}$ cooling in the other, allowing it to collapse to form a DCBH. Baryonic streaming may therefore play a crucial role in the formation of the seeds of the highest redshift quasars.

astro-ph.GA↗

arXiv2017

An analytic resolution to the competition between Lyman-Werner radiation and metal winds in direct collapse black hole hosts

A near pristine atomic cooling halo close to a star forming galaxy offers a natural pathway for forming massive direct collapse black hole (DCBH) seeds which could be the progenitors of the $z>6$ redshift quasars. The close proximity of the haloes enables a sufficient Lyman-Werner flux to effectively dissociate H$_2$ in the core of the atomic cooling halo. A mild background may also be required to delay star formation in the atomic cooling halo, often attributed to distant background galaxies. In this letter we investigate the impact of metal enrichment from both the background galaxies and the close star forming galaxy under extremely unfavourable conditions such as instantaneous metal mixing. We find that within the time window of DCBH formation, the level of enrichment never exceeds the critical threshold (Z$_{cr} \sim 1 \times 10^{-5} \ \rm Z_{\odot})$, and attains a maximum metallicity of Z $\sim 2 \times 10^{-6} \ \rm Z_{\odot}$. As the system evolves, the metallicity eventually exceeds the critical threshold, long after the DCBH has formed.

astro-ph.GA↗

arXiv2017

Rapid Formation of Massive Black Holes in close proximity to Embryonic Proto-Galaxies

The Direct Collapse Black Hole (DCBH) scenario provides a solution for forming the massive black holes powering bright quasars observed in the early Universe. A prerequisite for forming a DCBH is that the formation of (much less massive) Population III stars be avoided - this can be achieved by destroying H$_2$ via Lyman-Werner (LW) radiation (E$_{\rm{LW}}$ = 12.6 eV). We find that two conditions must be met in the proto-galaxy that will host the DCBH. First, prior star formation must be delayed; this can be achieved with a background LW flux of J$_{\rm BG} \gtrsim 100\ J_{21}$. Second, an intense burst of LW radiation from a neighbouring star-bursting proto-galaxy is required, just before the gas cloud undergoes gravitational collapse, to finally suppress star formation completely. We show here for the first time using high-resolution hydrodynamical simulations, including full radiative transfer, that this low-level background, combined with tight synchronisation and irradiation of a secondary proto-galaxy by a primary proto-galaxy, inevitably moves the secondary proto-galaxy onto the isothermal atomic cooling track, without the deleterious effects of either photo-evaporating the gas or polluting it by heavy elements. These, atomically cooled, massive proto-galaxies are expected to ultimately form a DCBH of mass $10^4 - 10^5 M_{\odot}$.

astro-ph.GA↗

arXiv2016

Grackle: a Chemistry and Cooling Library for Astrophysics

We present the Grackle chemistry and cooling library for astrophysical simulations and models. Grackle provides a treatment of non-equilibrium primordial chemistry and cooling for H, D, and He species, including H2 formation on dust grains; tabulated primordial and metal cooling; multiple UV background models; and support for radiation transfer and arbitrary heat sources. The library has an easily implementable interface for simulation codes written in C, C++, and Fortran as well as a Python interface with added convenience functions for semi-analytical models. As an open-source project, Grackle provides a community resource for accessing and disseminating astrochemical data and numerical methods. We present the full details of the core functionality, the simulation and Python interfaces, testing infrastructure, performance, and range of applicability. Grackle is a fully open-source project and new contributions are welcome.

astro-ph.CO↗

arXiv2016

Music from the heavens - Gravitational waves from supermassive black hole mergers in the EAGLE simulations

We estimate the expected event rate of gravitational wave signals from mergers of supermassive black holes that could be resolved by a space-based interferometer, such as the Evolved Laser Interferometer Space Antenna (eLISA), utilising the reference cosmological hydrodynamical simulation from the EAGLE suite. These simulations assume a $Λ$CDM cosmogony with state-of-the-art subgrid models for radiative cooling, star formation, stellar mass loss, and feedback from stars and accreting black holes. They have been shown to reproduce the observed galaxy population with unprecedented fidelity. We combine the merger rates of supermassive black holes in EAGLE with the latest phenomenological waveform models to calculate the gravitational waves signals from the intrinsic parameters of the merging black holes. The EAGLE models predict $\sim2$ detections per year by a gravitational wave detector such as eLISA. We find that these signals are largely dominated by mergers between seed mass black holes merging at redshifts between $z\sim2$ and $z\sim1$. In order to investigate the dependence on the assumed black hole seed mass, we introduce an additional model with a black hole seed mass an order of magnitude smaller than in our reference model. We also consider a variation of the reference model where a prescription for the expected delays in the black hole merger timescale has been included after their host galaxies merge. We find that the merger rate is similar in all models, but that the initial black hole seed mass could be distinguished through their detected gravitational waveforms. Hence, the characteristic gravitational wave signals detected by eLISA will provide profound insight into the origin of supermassive black holes and the initial mass distribution of black hole seeds.

astro-ph.GA↗