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John Robinson

Publications and source records attributed to John Robinson.

18 recordsLinked to original sources

Exploiting complex 3D-printed surface structures for portable quantum technologies

Portable quantum technologies require robust, lightweight apparatus with superior performance. For techniques dependent upon high-vacuum environments, such as atom interferometers and atomic clocks, 3D-printing enables new avenues to tailor in-vacuum gas propagation dynamics. We demonstrate intricate, fine-scale surface patterning of 3D-printed vacuum components to increase the rate at which gas particles collide with the surface. By applying a non-evaporable getter coating for use as a surface pump, we show that the patterned surface pumps gas particles 3.8 times faster than an equivalent flat areas. These patterns can be directly integrated into additively manufactured components, enabling application in close proximity to key experimental regions and contributing to overall mass-reduction. We develop numerical simulations that show good agreement with this result and predict up to a ten-fold increase in pumping rate, for realistic surface structures. Our work has direct applications in enabling passively-pumped portable quantum technologies, but also establishes 3D-printing as a powerful technique for the creation of optimized surface patterning to provide enhanced control over high-vacuum gas dynamics for a broad range of applications.

quant-ph

Large-scale quantum reservoir learning with an analog quantum computer

Quantum machine learning has gained considerable attention as quantum technology advances, presenting a promising approach for efficiently learning complex data patterns. Despite this promise, most contemporary quantum methods require significant resources for variational parameter optimization and face issues with vanishing gradients, leading to experiments that are either limited in scale or lack potential for quantum advantage. To address this, we develop a general-purpose, gradient-free, and scalable quantum reservoir learning algorithm that harnesses the quantum dynamics of neutral-atom analog quantum computers to process data. We experimentally implement the algorithm, achieving competitive performance across various categories of machine learning tasks, including binary and multi-class classification, as well as timeseries prediction. Effective and improving learning is observed with increasing system sizes of up to 108 qubits, demonstrating the largest quantum machine learning experiment to date. We further observe comparative quantum kernel advantage in learning tasks by constructing synthetic datasets based on the geometric differences between generated quantum and classical data kernels. Our findings demonstrate the potential of utilizing classically intractable quantum correlations for effective machine learning. We expect these results to stimulate further extensions to different quantum hardware and machine learning paradigms, including early fault-tolerant hardware and generative machine learning tasks.

quant-ph

Surface-based parcellation and vertex-wise analysis of ultra high-resolution ex vivo 7 tesla MRI in Alzheimer's disease and related dementias

Magnetic resonance imaging (MRI) is the standard modality to understand human brain structure and function in vivo (antemortem). Decades of research in human neuroimaging has led to the widespread development of methods and tools to provide automated volume-based segmentations and surface-based parcellations which help localize brain functions to specialized anatomical regions. Recently ex vivo (postmortem) imaging of the brain has opened-up avenues to study brain structure at sub-millimeter ultra high-resolution revealing details not possible to observe with in vivo MRI. Unfortunately, there has been limited methodological development in ex vivo MRI primarily due to lack of datasets and limited centers with such imaging resources. Therefore, in this work, we present one-of-its-kind dataset of 82 ex vivo T2w whole brain hemispheres MRI at 0.3 mm isotropic resolution spanning Alzheimer's disease and related dementias. We adapted and developed a fast and easy-to-use automated surface-based pipeline to parcellate, for the first time, ultra high-resolution ex vivo brain tissue at the native subject space resolution using the Desikan-Killiany-Tourville (DKT) brain atlas. This allows us to perform vertex-wise analysis in the template space and thereby link morphometry measures with pathology measurements derived from histology. We will open-source our dataset docker container, Jupyter notebooks for ready-to-use out-of-the-box set of tools and command line options to advance ex vivo MRI clinical brain imaging research on the project webpage.

cs.CV

Automated deep learning segmentation of high-resolution 7 T postmortem MRI for quantitative analysis of structure-pathology correlations in neurodegenerative diseases

Postmortem MRI allows brain anatomy to be examined at high resolution and to link pathology measures with morphometric measurements. However, automated segmentation methods for brain mapping in postmortem MRI are not well developed, primarily due to limited availability of labeled datasets, and heterogeneity in scanner hardware and acquisition protocols. In this work, we present a high resolution of 135 postmortem human brain tissue specimens imaged at 0.3 mm$^{3}$ isotropic using a T2w sequence on a 7T whole-body MRI scanner. We developed a deep learning pipeline to segment the cortical mantle by benchmarking the performance of nine deep neural architectures, followed by post-hoc topological correction. We then segment four subcortical structures (caudate, putamen, globus pallidus, and thalamus), white matter hyperintensities, and the normal appearing white matter. We show generalizing capabilities across whole brain hemispheres in different specimens, and also on unseen images acquired at 0.28 mm^3 and 0.16 mm^3 isotropic T2*w FLASH sequence at 7T. We then compute localized cortical thickness and volumetric measurements across key regions, and link them with semi-quantitative neuropathological ratings. Our code, Jupyter notebooks, and the containerized executables are publicly available at: https://pulkit-khandelwal.github.io/exvivo-brain-upenn

cs.CV

Gray Matter Segmentation in Ultra High Resolution 7 Tesla ex vivo T2w MRI of Human Brain Hemispheres

Ex vivo MRI of the brain provides remarkable advantages over in vivo MRI for visualizing and characterizing detailed neuroanatomy. However, automated cortical segmentation methods in ex vivo MRI are not well developed, primarily due to limited availability of labeled datasets, and heterogeneity in scanner hardware and acquisition protocols. In this work, we present a high resolution 7 Tesla dataset of 32 ex vivo human brain specimens. We benchmark the cortical mantle segmentation performance of nine neural network architectures, trained and evaluated using manually-segmented 3D patches sampled from specific cortical regions, and show excellent generalizing capabilities across whole brain hemispheres in different specimens, and also on unseen images acquired at different magnetic field strength and imaging sequences. Finally, we provide cortical thickness measurements across key regions in 3D ex vivo human brain images. Our code and processed datasets are publicly available at https://github.com/Pulkit-Khandelwal/picsl-ex-vivo-segmentation.

eess.IV

Post-Quantum Security for Ultra-Reliable Low-Latency Heterogeneous Networks

We consider the problem of post-quantum secure and ultra-reliable communication through a heterogeneous network consisting of multiple connections. Three performance metrics are considered: security, throughput, and in-order delivery delay. In this setting, previous work has looked, individually, at the trade-offs between in-order delivery delay and throughput, and between security and throughput. This is the first work considering the trade-off between all three for heterogeneous communication networks, while taking the computational complexity into account. We present LL-HUNCC, a low latency hybrid universal network coding cryptosystem. LL-HUNCC is an efficient coding scheme which allows for secure communications over a noisy untrusted heterogeneous network by encrypting only a small part of the information being sent. This scheme provides post-quantum security with high throughput and low in-order delivery delay guarantees. We evaluate LL-HUNCC via simulations on a setting inspired by a practical scenario for heterogeneous communications involving a satellite communication link and a 5G communication network. Under this scenario, we compare LL-HUNCC to the state-of-the-art where all communication paths are encrypted via a post-quantum public-key cryptosystem.

cs.IT

Masked Conditional Neural Networks for Automatic Sound Events Recognition

Deep neural network architectures designed for application domains other than sound, especially image recognition, may not optimally harness the time-frequency representation when adapted to the sound recognition problem. In this work, we explore the ConditionaL Neural Network (CLNN) and the Masked ConditionaL Neural Network (MCLNN) for multi-dimensional temporal signal recognition. The CLNN considers the inter-frame relationship, and the MCLNN enforces a systematic sparseness over the network's links to enable learning in frequency bands rather than bins allowing the network to be frequency shift invariant mimicking a filterbank. The mask also allows considering several combinations of features concurrently, which is usually handcrafted through exhaustive manual search. We applied the MCLNN to the environmental sound recognition problem using the ESC-10 and ESC-50 datasets. MCLNN achieved competitive performance, using 12% of the parameters and without augmentation, compared to state-of-the-art Convolutional Neural Networks.

cs.LG

Automatic Classification of Music Genre using Masked Conditional Neural Networks

Neural network based architectures used for sound recognition are usually adapted from other application domains such as image recognition, which may not harness the time-frequency representation of a signal. The ConditionaL Neural Networks (CLNN) and its extension the Masked ConditionaL Neural Networks (MCLNN) are designed for multidimensional temporal signal recognition. The CLNN is trained over a window of frames to preserve the inter-frame relation, and the MCLNN enforces a systematic sparseness over the network's links that mimics a filterbank-like behavior. The masking operation induces the network to learn in frequency bands, which decreases the network susceptibility to frequency-shifts in time-frequency representations. Additionally, the mask allows an exploration of a range of feature combinations concurrently analogous to the manual handcrafting of the optimum collection of features for a recognition task. MCLNN have achieved competitive performance on the Ballroom music dataset compared to several hand-crafted attempts and outperformed models based on state-of-the-art Convolutional Neural Networks.

cs.SD

Recognition of Acoustic Events Using Masked Conditional Neural Networks

Automatic feature extraction using neural networks has accomplished remarkable success for images, but for sound recognition, these models are usually modified to fit the nature of the multi-dimensional temporal representation of the audio signal in spectrograms. This may not efficiently harness the time-frequency representation of the signal. The ConditionaL Neural Network (CLNN) takes into consideration the interrelation between the temporal frames, and the Masked ConditionaL Neural Network (MCLNN) extends upon the CLNN by forcing a systematic sparseness over the network's weights using a binary mask. The masking allows the network to learn about frequency bands rather than bins, mimicking a filterbank used in signal transformations such as MFCC. Additionally, the Mask is designed to consider various combinations of features, which automates the feature hand-crafting process. We applied the MCLNN for the Environmental Sound Recognition problem using the Urbansound8k, YorNoise, ESC-10 and ESC-50 datasets. The MCLNN have achieved competitive performance compared to state-of-the-art Convolutional Neural Networks and hand-crafted attempts.

cs.LG

Masked Conditional Neural Networks for Environmental Sound Classification

The ConditionaL Neural Network (CLNN) exploits the nature of the temporal sequencing of the sound signal represented in a spectrogram, and its variant the Masked ConditionaL Neural Network (MCLNN) induces the network to learn in frequency bands by embedding a filterbank-like sparseness over the network's links using a binary mask. Additionally, the masking automates the exploration of different feature combinations concurrently analogous to handcrafting the optimum combination of features for a recognition task. We have evaluated the MCLNN performance using the Urbansound8k dataset of environmental sounds. Additionally, we present a collection of manually recorded sounds for rail and road traffic, YorNoise, to investigate the confusion rates among machine generated sounds possessing low-frequency components. MCLNN has achieved competitive results without augmentation and using 12% of the trainable parameters utilized by an equivalent model based on state-of-the-art Convolutional Neural Networks on the Urbansound8k. We extended the Urbansound8k dataset with YorNoise, where experiments have shown that common tonal properties affect the classification performance.

cs.LG

Environmental Sound Recognition using Masked Conditional Neural Networks

Neural network based architectures used for sound recognition are usually adapted from other application domains, which may not harness sound related properties. The ConditionaL Neural Network (CLNN) is designed to consider the relational properties across frames in a temporal signal, and its extension the Masked ConditionaL Neural Network (MCLNN) embeds a filterbank behavior within the network, which enforces the network to learn in frequency bands rather than bins. Additionally, it automates the exploration of different feature combinations analogous to handcrafting the optimum combination of features for a recognition task. We applied the MCLNN to the environmental sounds of the ESC-10 dataset. The MCLNN achieved competitive accuracies compared to state-of-the-art convolutional neural networks and hand-crafted attempts.

cs.LG

Music Genre Classification using Masked Conditional Neural Networks

The ConditionaL Neural Networks (CLNN) and the Masked ConditionaL Neural Networks (MCLNN) exploit the nature of multi-dimensional temporal signals. The CLNN captures the conditional temporal influence between the frames in a window and the mask in the MCLNN enforces a systematic sparseness that follows a filterbank-like pattern over the network links. The mask induces the network to learn about time-frequency representations in bands, allowing the network to sustain frequency shifts. Additionally, the mask in the MCLNN automates the exploration of a range of feature combinations, usually done through an exhaustive manual search. We have evaluated the MCLNN performance using the Ballroom and Homburg datasets of music genres. MCLNN has achieved accuracies that are competitive to state-of-the-art handcrafted attempts in addition to models based on Convolutional Neural Networks.

cs.LG

Masked Conditional Neural Networks for Audio Classification

We present the ConditionaL Neural Network (CLNN) and the Masked ConditionaL Neural Network (MCLNN) designed for temporal signal recognition. The CLNN takes into consideration the temporal nature of the sound signal and the MCLNN extends upon the CLNN through a binary mask to preserve the spatial locality of the features and allows an automated exploration of the features combination analogous to hand-crafting the most relevant features for the recognition task. MCLNN has achieved competitive recognition accuracies on the GTZAN and the ISMIR2004 music datasets that surpass several state-of-the-art neural network based architectures and hand-crafted methods applied on both datasets.

stat.ML

High-performance near- and mid-infrared crystalline coatings

Substrate-transferred crystalline coatings have recently emerged as a groundbreaking new concept in optical interference coatings. Building upon our initial demonstration of this technology, we have now realized significant improvements in the limiting optical performance of these novel single-crystal $GaAs/Al_{x}Ga_{1-x}As$ multilayers. In the near-infrared (NIR), for coating center wavelengths spanning 1064 to 1560 nm, we have reduced the excess optical losses (scatter + absorption) to levels as low as 3 parts per million, enabling the realization of a cavity finesse exceeding $3\times 10^{5}$ at the telecom-relevant wavelength range near 1550 nm. Moreover, we demonstrate the direct measurement of sub-ppm optical absorption at 1064 nm. Concurrently, we investigate the mid-IR (MIR) properties of these coatings and observe exceptional performance for first attempts in this important wavelength region. Specifically, we verify excess losses at the hundred ppm level for wavelengths of 3300 and 3700 nm. Taken together, our NIR optical losses are now fully competitive with ion beam sputtered multilayer coatings, while our first prototype MIR optics have already reached state-of-the-art performance levels for reflectors covering this portion of the fingerprint region for optical gas sensing. Mirrors fabricated with our crystalline coating technique exhibit the lowest mechanical loss, and thus the lowest Brownian noise, the highest thermal conductivity, and, potentially, the widest spectral coverage of any "supermirror" technology in a single material platform. Looking ahead, we see a bright future for crystalline coatings in applications requiring the ultimate levels of optical, thermal, and optomechanical performance

cond-mat.mtrl-sci

A new permutation test statistic for complete block designs

We introduce a nonparametric test statistic for the permutation test in complete block designs. We find the region in which the statistic exists and consider particularly its properties on the boundary of the region. Further, we prove that saddlepoint approximations for tail probabilities can be obtained inside the interior of this region. Finally, numerical examples are given showing that both accuracy and power of the new statistic improves on these properties of the classical $F$-statistic under some non-Gaussian models and equals them for the Gaussian case.

math.ST

Relative errors for bootstrap approximations of the serial correlation coefficient

We consider the first serial correlation coefficient under an AR(1) model where errors are not assumed to be Gaussian. In this case it is necessary to consider bootstrap approximations for tests based on the statistic since the distribution of errors is unknown. We obtain saddle-point approximations for tail probabilities of the statistic and its bootstrap version and use these to show that the bootstrap tail probabilities approximate the true values with given relative errors, thus extending the classical results of Daniels [Biometrika 43 (1956) 169-185] for the Gaussian case. The methods require conditioning on the set of odd numbered observations and suggest a conditional bootstrap which we show has similar relative error properties.

math.ST

Saddlepoint approximations for likelihood ratio like statistics with applications to permutation tests

We obtain two theorems extending the use of a saddlepoint approximation to multiparameter problems for likelihood ratio-like statistics which allow their use in permutation and rank tests and could be used in bootstrap approximations. In the first, we show that in some cases when no density exists, the integral of the formal saddlepoint density over the set corresponding to large values of the likelihood ratio-like statistic approximates the true probability with relative error of order $1/n$. In the second, we give multivariate generalizations of the Lugannani--Rice and Barndorff-Nielsen or $r^*$ formulas for the approximations. These theorems are applied to obtain permutation tests based on the likelihood ratio-like statistics for the $k$ sample and the multivariate two-sample cases. Numerical examples are given to illustrate the high degree of accuracy, and these statistics are compared to the classical statistics in both cases.

math.ST

Cramér-type large deviations for samples from a finite population

Cramér-type large deviations for means of samples from a finite population are established under weak conditions. The results are comparable to results for the so-called self-normalized large deviation for independent random variables. Cramér-type large deviations for the finite population Student $t$-statistic are also investigated.

math.ST