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Jona Carmon

Publications and source records attributed to Jona Carmon.

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Capturing Inner Experience At Scale: An AI Interviewer Co-Developed with the Founder of a Landmark Phenomenological Method

Subjective experience is central to psychological science, yet methods for studying it force a choice between depth and scale. Classical Experience sampling, as in ecological momentary assessments (EMA), captures experience as it occurs, but it confines participants to predetermined response formats that prescribe how experience is measured. Descriptive Experience Sampling (DES) instead investigates specific moments in depth through expert expositional interviews, but its reliance on scarce trained interviewers keeps samples small. Large language model (LLM) systems can scale qualitative interviewing. Some models operationalize established interviewing methods such as motivational interviewing, yet none is grounded in a method for apprehending inner experience. Here we present an AI interviewer that aspires to operationalize DES into an explicit, inspectable reasoning architecture. At each turn it appraises the participant's message across eleven quality dimensions, maintains a conservative account of what has been established, selects a stage-appropriate intervention, and composes a single non-leading query, always holding that temporal grounding precedes experiential content. It was derived from the full corpus of DES transcripts and refined with the method's originator Russell T. Hurlburt. To our knowledge it is the first AI interviewer grounded in an established method for studying inner experience. The interviewer runs inside Introscope, an application that delivers the beeps and conducts the interviews and a study platform that lets researchers run studies via shareable links and review the sampled experience. It is demonstrated in an accompanying video https://introscope.mpib-berlin.mpg.de/video. Pending validation studies, we will make it freely available to researchers and the public, for crowdsourced sampling and individual exploration of inner experience.

q-bio.NC

Uncertainty promotes neuroreductionism: A behavioral online study on folk psychological causal inference from neuroimaging data

Introduction. Increased efforts in neuroscience try to understand mental disorders as brain disorders. In the present study we investigate how common a neuroreductionist inclination is among highly educated people. In particular, we shed light on implicit presuppositions of mental disorders little is known about in the public, exemplified here by the case of Body Integrity Dysphoria (BID) that is considered a mental disorder for the first time in ICD-11. Methods. Identically graphed, simulated data of mind-brain correlations were shown in three contexts with presumably different presumptions about causality. 738 highly-educated laymen rated plausibility of causality attribution from brain to mind and from mind to brain for correlations between brain structural properties and mental phenomena. We contrasted participants' plausibility ratings of causality in the contexts of commonly perceived brain-lesion induced behavior (aphasia), behavior-induced training effects (piano playing), and a newly described mental disorder (BID). Results. The findings reveal the expected context-dependent modulation of causality attributions in the contexts of aphasia and piano playing. Furthermore, we observed a significant tendency to more readily attribute causal inference from brain to mind than vice versa with respect to BID. Conclusion. In some contexts, exemplified here by aphasia and piano playing, unidirectional causality attributions may be justified. However, with respect to BID, we critically discuss presumably unjustified neuroreductionist inclinations under causal uncertainty. Finally, we emphasize the need for a presupposition-free approach in psychiatry.

q-bio.NC

Reliability and comparability of human brain structural covariance networks

Structural covariance analysis is a widely used structural MRI analysis method which characterises the co-relations of morphology between brain regions over a group of subjects. To our knowledge, little has been investigated in terms of the comparability of results between different data sets or the reliability of results over the same subjects in different rescan sessions, image resolutions, or FreeSurfer versions. In terms of comparability, our results show substantial differences in the structural covariance matrix between data sets of age- and sex-matched healthy human adults. These differences persist after site correction, they are exacerbated by low sample sizes, and they are most pronounced when using average cortical thickness as a morphological measure. Down-stream graph theoretic analyses further show statistically significant differences. In terms of reliability, substantial differences were also found when comparing repeated scan sessions of the same subjects, and image resolutions and FreeSurfer versions of the same image. We could further estimate the relative measurement error and showed that it is largest when using thickness. With simulated data, we argue that cortical thickness is least reliable because of larger relative measurement errors. Practically, we make the following recommendations (1) pooling subjects across sites into one group should be avoided, particularly if sites differ in image resolutions, demographics, or preprocessing; (2) surface area and volume should be preferred as morphological measures over cortical thickness; (3) a large number of subjects should be used to estimate structural covariance; (4) measurement error should be assessed where repeated measurements are available; (5) if combining sites is critical, univariate site-correction is insufficient, but error covariance should be explicitly measured and modelled.

q-bio.NC