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Jonas Franke

Publications and source records attributed to Jonas Franke.

5 recordsLinked to original sources

Spatially or temporally resolved phase-based optoretinography with actively-tracked point-scanning optical coherence tomography

Optoretinography is a promising approach to measure visual function but its clinical translation has remained confined to research settings due to demanding hardware requirements. Here, we demonstrate that high-quality phase-based optoretinography can be performed using conventional point-scanning spectral-domain optical coherence tomography. We show that the need for high imaging speed can be circumvented by accurate sampling of phase changes at consistent spatial location. Light-evoked outer-segment expansion could be temporally resolved in B-scan series acquired at a fixed position when filtering off-location B-scans, and spatially resolved in volumes acquired at rates as low as 1~Hz. These results indicate that the technical barrier for phase-based optoretinography is substantially lower than previously assumed and pave the way toward broad clinical translation.

physics.optics

Measuring choriocapillaris blood flow with laser Doppler optical coherence tomography

We report on using a laser Doppler processing of Fourier-domain optical coherence tomography (OCT) data for the assessment of pulsatile blood flow in the choriocapillaris. Signal fluctuations in B-scans recorded at 2 kHz were analyzed by Fourier transform to extract blood flow information. The spectral broadening of light backscattered by the choriocapillaris was used to derive a choriocapillaris flow velocity index in physical units, with sufficient temporal resolution to capture heartbeat-induced variations. Furthermore, the asymmetry in the spectral broadening enabled us to determine the axial direction of blood flow with high sensitivity, allowing for the detection of flow orientation in retinal capillaries. This approach is promising as it can be directly implemented on widely available fast-scanning Fourier-domain OCT instruments.

physics.optics

Diffuse-illumination holographic optical coherence tomography

Holographic optical coherence tomography (OCT) is a powerful imaging technique, but its ability to reveal low-reflectivity features is limited. In this study, we performed holographic OCT by incoherently averaging volumes with changing diffuse illumination of numerical aperture (NA) equal to the detection NA. While the reduction of speckle from singly scattered light is only modest, we discovered that speckle from multiply scattered light can be arbitrarily reduced, resulting in substantial improvements in image quality. This technique also offers the advantage of suppressing noises arising from spatial coherence, and can be implemented with a partially spatially incoherent light source for further mitigation of multiple scattering. Finally, we show that although holographic reconstruction capabilities are increasingly lost with decreasing spatial coherence, they can be retained over an axial range sufficient to standard OCT applications.

physics.optics

PECVD and PEALD on polymer substrates (Part II): Understanding and tuning of barrier and membrane properties of thin films

This feature article presents insights concerning the correlation of PECVD and PEALD thin film structures with their barrier or membrane properties. While in principle similar precursor gases and processes can be applied, the adjustment of deposition parameters for different polymer substrates can lead to either an effective diffusion barrier or selective permeabilities. In both cases the understanding of the film growth and the analysis of the pore size distribution and the pore surface chemistry is of utmost importance for the understanding of the related transport properties of small molecules. In this regard the article presents both concepts of thin film engineering and analytical as well as theoretical approaches leading to a comprehensive description of the state of the art in this field. Moreover, based on the presented correlation of film structure and molecular transport properties perspectives of future relevant research in this area is presented.

cond-mat.soft

Computational timbre and tonal system similarity analysis of the music of Northern Myanmar-based Kachin compared to Xinjiang-based Uyghur ethnic groups

The music of Northern Myanmar Kachin ethnic group is compared to the music of western China, Xijiang based Uyghur music, using timbre and pitch feature extraction and machine learning. Although separated by Tibet, the muqam tradition of Xinjiang might be found in Kachin music due to myths of Kachin origin, as well as linguistic similarities, e.g., the Kachin term 'makan' for a musical piece. Extractions were performed using the apollon and COMSAR (Computational Music and Sound Archiving) frameworks, on which the Ethnographic Sound Recordings Archive (ESRA) is based, using ethnographic recordings from ESRA next to additional pieces. In terms of pitch, tonal systems were compared using Kohonen self-organizing map (SOM), which clearly clusters Kachin and Uyghur musical pieces. This is mainly caused by the Xinjiang muqam music showing just fifth and fourth, while Kachin pieces tend to have a higher fifth and fourth, next to other dissimilarities. Also, the timbre features of spectral centroid and spectral sharpness standard deviation clearly tells Uyghur from Kachin pieces, where Uyghur music shows much larger deviations. Although more features will be compared in the future, like rhythm or melody, these already strong findings might introduce an alternative comparison methodology of ethnic groups beyond traditional linguistic definitions.

cs.SD