arXiv subjects

Jonghun Lee

Publications and source records attributed to Jonghun Lee.

6 recordsLinked to original sources

arXiv2026

High-Fidelity Transcranial Ultrasound Multi-focal Stimulation via Physics-Aware Hologram Technique

Transcranial ultrasound stimulation (TUS) offers non-invasive deep-brain neuromodulation with high spatial precision, but reliably generating complex multi-target acoustic fields through the skull remains challenging. Here, we introduce a physics-aware hologram technique that directly generates fabrication-ready holographic implementations while preserving consistency between numerical field synthesis and physical acoustic realization. The method enables single-, dual-, and tri-focal transcranial stimulation patterns and was validated through in silico simulations, ex vivo skull measurements, and in vivo experiments. Compared with representative state-of-the-art methods, the proposed approach improved focal reconstruction and energy confinement at intended targets while reducing off-target acoustic leakage. In a neuropathic-pain mouse model, simultaneous bilateral stimulation of thalamic nuclei reduced c-Fos expression and showed preliminary improvements in pain-related behavioral responses. These findings support the use of fabrication-consistent holographic design for spatially localized and reproducible multi-target transcranial neuromodulation.

eess.SY↗

arXiv2026

TriGen: NPU Architecture for End-to-End Acceleration of Large Language Models based on SW-HW Co-Design

Recent studies have extensively explored NPU architectures for accelerating AI inference in on-device environments, which are inherently resource-constrained. Meanwhile, transformer-based large language models (LLMs) have become dominant, with rapidly increasing model sizes but low degree of parameter reuse compared to conventional CNNs, making end-to-end execution on resource-limited devices extremely challenging. To address these challenges, we propose TriGen, a novel NPU architecture tailored for resource-constrained environments through software-hardware co-design. Firstly, TriGen adopts low-precision computation using microscaling (MX) to enable additional optimization opportunities while preserving accuracy, and resolves the issues that arise by employing such precision. Secondly, to jointly optimize both nonlinear and linear operations, TriGen eliminates the need for specialized hardware for essential nonlinear operations by using fast and accurate LUT, thereby maximizing performance gains and reducing hardware-cost in on-device environments, and finally, by taking practical hardware constraints into account, further employs scheduling techniques to maximize computational utilization even under limited on-chip memory capacity. We evaluate the performance of TriGen on various LLMs and show that TriGen achieves an average 2.73x performance speedup and 52% less memory transfer over the baseline NPU design with negligible accuracy loss.

cs.AR↗

arXiv2025

Continuum Dropout for Neural Differential Equations

Neural Differential Equations (NDEs) excel at modeling continuous-time dynamics, effectively handling challenges such as irregular observations, missing values, and noise. Despite their advantages, NDEs face a fundamental challenge in adopting dropout, a cornerstone of deep learning regularization, making them susceptible to overfitting. To address this research gap, we introduce Continuum Dropout, a universally applicable regularization technique for NDEs built upon the theory of alternating renewal processes. Continuum Dropout formulates the on-off mechanism of dropout as a stochastic process that alternates between active (evolution) and inactive (paused) states in continuous time. This provides a principled approach to prevent overfitting and enhance the generalization capabilities of NDEs. Moreover, Continuum Dropout offers a structured framework to quantify predictive uncertainty via Monte Carlo sampling at test time. Through extensive experiments, we demonstrate that Continuum Dropout outperforms existing regularization methods for NDEs, achieving superior performance on various time series and image classification tasks. It also yields better-calibrated and more trustworthy probability estimates, highlighting its effectiveness for uncertainty-aware modeling.

stat.ML↗

arXiv2025

DGSAM: Domain Generalization via Individual Sharpness-Aware Minimization

Domain generalization (DG) aims to learn models that perform well on unseen target domains by training on multiple source domains. Sharpness-Aware Minimization (SAM), known for finding flat minima that improve generalization, has therefore been widely adopted in DG. However, our analysis reveals that SAM in DG may converge to \textit{fake flat minima}, where the total loss surface appears flat in terms of global sharpness but remains sharp with respect to individual source domains. To understand this phenomenon more precisely, we formalize the average worst-case domain risk as the maximum loss under domain distribution shifts within a bounded divergence, and derive a generalization bound that reveals the limitations of global sharpness-aware minimization. In contrast, we show that individual sharpness provides a valid upper bound on this risk, making it a more suitable proxy for robust domain generalization. Motivated by these insights, we shift the DG paradigm toward minimizing individual sharpness across source domains. We propose \textit{Decreased-overhead Gradual SAM (DGSAM)}, which applies gradual domain-wise perturbations in a computationally efficient manner to consistently reduce individual sharpness. Extensive experiments demonstrate that DGSAM not only improves average accuracy but also reduces performance variance across domains, while incurring less computational overhead than SAM.

stat.ML↗

arXiv2025

Comprehensive Review of Neural Differential Equations for Time Series Analysis

Time series modeling and analysis have become critical in various domains. Conventional methods such as RNNs and Transformers, while effective for discrete-time and regularly sampled data, face significant challenges in capturing the continuous dynamics and irregular sampling patterns inherent in real-world scenarios. Neural Differential Equations (NDEs) represent a paradigm shift by combining the flexibility of neural networks with the mathematical rigor of differential equations. This paper presents a comprehensive review of NDE-based methods for time series analysis, including neural ordinary differential equations, neural controlled differential equations, and neural stochastic differential equations. We provide a detailed discussion of their mathematical formulations, numerical methods, and applications, highlighting their ability to model continuous-time dynamics. Furthermore, we address key challenges and future research directions. This survey serves as a foundation for researchers and practitioners seeking to leverage NDEs for advanced time series analysis.

cs.LG↗

arXiv2018

Tunable Assembly of Gold Nanorods in Polymer Solutions to Generate Controlled Nanostructured Materials

Gold nanorods grafted with short chain polymers are assembled into controlled open structures using polymer-induced depletion interactions and structurally characterized using small angle x-ray scattering. When the nanorod diameter is smaller than the radius of gyration of the depletant polymer, the depletion interaction depends solely on the correlation length of the polymer solution and not directly on the polymer molecular weight. As the polymer concentration increases, the stronger depletion interactions increasingly compress the grafted chains and push the gold nanorods closer together. By contrast, other structural characteristics such as the number of nearest neighbors and fractal dimension exhibit a non-monotonic dependence on polymer concentration. These parameters are maximal at intermediate concentrations, which are attributed to a crossover from reaction-limited to diffusion-limited aggregation. The control over structural properties of anisotropic nanoscale building blocks demonstrated here will be beneficial to designing and producing materials \emph{in situ} with specific direction-dependent nanoscale properties and provides a crucial route for advances in additive manufacturing.

cond-mat.soft↗