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Joohoon Lee

Publications and source records attributed to Joohoon Lee.

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Benchmarking Vision-Language Models for Automated Pathology Diagnosis and Report Generation

The rapid advancement of vision-language models (VLMs) has accelerated progress in computational pathology; however, whole-slide image (WSI)-based pathology report generation remains limited by the scarcity of large-scale WSI--report datasets and the complexity of mapping spatially distributed visual patterns to structured clinical text. To address this, we introduce a clinically curated Pan-Asia WSI--report dataset of approximately 10,500 pairs from five institutions and establish the REG 2025 benchmark through a MICCAI challenge for systematic evaluation of multimodal models. We analyze submitted methods spanning pretrained VLMs, multiple-instance learning frameworks, hierarchical expert models, retrieval-augmented generation, and cross-modal Transformers. Rather than indicating that VLM use alone was sufficient for superior performance, the results suggest that top-performing methods benefited from structured report representations, hierarchical diagnostic decomposition, and effective multimodal grounding. We identify key limitations, including instability in quantitative attribute estimation (e.g., numeric hallucination) and a tendency toward diagnostic overspecification, with some errors resembling known diagnostic pitfalls in routine pathology. These findings establish REG 2025 as a benchmark for evaluating WSI-based structured report generation and vision-language understanding in computational pathology, providing insights for the design of clinically grounded multimodal pathology models.

cs.CV

On Epistemic Uncertainty of Visual Tokens for Object Hallucinations in Large Vision-Language Models

Large vision-language models (LVLMs), which integrate a vision encoder (VE) with a large language model, have achieved remarkable success across various tasks. However, there are still crucial challenges in LVLMs such as object hallucination, generating descriptions of objects that are not in the input image. Here, we argue that uncertain visual tokens within the VE is a key factor that contributes to object hallucination. Our statistical analysis found that there are positive correlations between visual tokens with high epistemic uncertainty and the occurrence of hallucinations. Furthermore, we show theoretically and empirically that visual tokens in early VE layers that exhibit large representation deviations under small adversarial perturbations indicate high epistemic uncertainty. Based on these findings, we propose a simple yet effective strategy to mitigate object hallucination by modifying the VE only. Our method comprises a proxy method with adversarial perturbations for identifying uncertain visual tokens efficiently and a method to mask these uncertain visual tokens during the self-attention process in the middle layers of the VE, suppressing their influence on visual encoding and thus alleviating hallucinations. Extensive experiments show that our method significantly reduces object hallucinations in LVLMs and can synergistically work with other prior arts.

cs.CV

Geometrical Properties of Text Token Embeddings for Strong Semantic Binding in Text-to-Image Generation

Text-to-image (T2I) models often suffer from text-image misalignment in complex scenes involving multiple objects and attributes. Semantic binding has attempted to associate the generated attributes and objects with their corresponding noun phrases (NPs) by text or latent optimizations with the modulation of cross-attention (CA) maps; yet, the factors that influence semantic binding remain underexplored. Here, we investigate the geometrical properties of text token embeddings and their CA maps. We found that the geometrical properties of token embeddings, specifically angular distances and norms, are crucial factors in the differentiation of the CA map. These theoretical findings led to our proposed training-free text-embedding-aware T2I framework, dubbed \textbf{TokeBi}, for strong semantic binding. TokeBi consists of Causality-Aware Projection-Out (CAPO) for distinguishing inter-NP CA maps and Adaptive Token Mixing (ATM) for enhancing inter-NP separation while maintaining intra-NP cohesion in CA maps. Extensive experiments confirm that TokeBi outperforms prior arts across diverse baselines and datasets.

cs.CV