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Jooyeon Lee

Publications and source records attributed to Jooyeon Lee.

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Bayesian Geostatistical Modeling for Cluster Randomized Trials

Cluster randomized trials (CRTs) offer a practical alternative for addressing logistical challenges and ensuring feasibility in community health, education, and prevention studies, even though individually-randomized controlled trials are considered the gold standard in evaluating therapeutic interventions. Despite their utility, CRTs are often criticized for limited precision and complex modeling requirements. Advances in robust Bayesian methods and the incorporation of spatial correlation into CRT design and analysis remain relatively underdeveloped. This paper introduces a Bayesian geostatistical framework that models individuals nested within geographic clusters while explicitly accounting for spatial dependence. We demonstrate that conventional non-spatial models are susceptible to underestimating uncertainty and lead to misleading inferences, whereas our spatial approach improves estimation stability, controls type I error, and enhances statistical power. Additionally, we explore design implications that are suggested through the exploration of spatial predictive uncertainty. Our results of simulation and real-world data application demonstrate the value and need for wider adoption of spatial methods in CRTs.

stat.ME

Efficient AI-Driven Multi-Section Whole Slide Image Analysis for Biochemical Recurrence Prediction in Prostate Cancer

Prostate cancer is one of the most frequently diagnosed malignancies in men worldwide. However, precise prediction of biochemical recurrence (BCR) after radical prostatectomy remains challenging due to the multifocality of tumors distributed throughout the prostate gland. In this paper, we propose a novel AI framework that simultaneously processes a series of multi-section pathology slides to capture the comprehensive tumor landscape across the entire prostate gland. To develop this predictive AI model, we curated a large-scale dataset of 23,451 slides from 789 patients. The proposed framework demonstrated strong predictive performance for 1- and 2-year BCR prediction, substantially outperforming established clinical benchmarks. The AI-derived risk score was validated as the most potent independent prognostic factor in a multivariable Cox proportional hazards analysis, surpassing conventional clinical markers such as pre-operative PSA and Gleason score. Furthermore, we demonstrated that integrating patch and slide sub-sampling strategies significantly reduces computational cost during both training and inference without compromising predictive performance, and generalizability of AI was confirmed through external validation. Collectively, these results highlight the clinical feasibility and prognostic value of the proposed AI-based multi-section slide analysis as a scalable tool for post-operative management in prostate cancer.

cs.CV

SalamNET at SemEval-2020 Task12: Deep Learning Approach for Arabic Offensive Language Detection

This paper describes SalamNET, an Arabic offensive language detection system that has been submitted to SemEval 2020 shared task 12: Multilingual Offensive Language Identification in Social Media. Our approach focuses on applying multiple deep learning models and conducting in depth error analysis of results to provide system implications for future development considerations. To pursue our goal, a Recurrent Neural Network (RNN), a Gated Recurrent Unit (GRU), and Long-Short Term Memory (LSTM) models with different design architectures have been developed and evaluated. The SalamNET, a Bi-directional Gated Recurrent Unit (Bi-GRU) based model, reports a macro-F1 score of 0.83.

cs.CL