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Jose Rodrigo Rojo-Garcia

Publications and source records attributed to Jose Rodrigo Rojo-Garcia.

3 recordsLinked to original sources

Bayesian optimal experimental design with Wasserstein information criteria

Bayesian optimal experimental design (OED) provides a principled framework for selecting observations or experiments. We introduce new Bayesian design criteria based on the expected Wasserstein-$p$ distance between the prior and posterior distributions, termed Wasserstein information criteria. These criteria have many parallels with the widely used expected information gain (EIG) criterion, which instead relies on the Kullback--Leibler divergence. We show that the Wasserstein-$2$ criterion admits a closed-form solution in the linear-Gaussian setting, a property which can be used for more general approximation schemes, and contrast this solution with classical notions of Bayesian alphabetic optimality. Then we develop a stability analysis of the Wasserstein-$1$ criterion, wherein we bound errors induced by perturbations of the prior or likelihood. We partially extend this analysis to the Wasserstein-$2$ criterion. In particular, these results yield error rates for empirical approximations of the prior. We then illustrate the computability of the Wasserstein-$2$ criterion and demonstrate our approximation rates through simulations.

stat.ME↗

Surrogate model for Bayesian optimal experimental design in chromatography

We applied Bayesian Optimal Experimental Design (OED) in the estimation of parameters involved in the Equilibrium Dispersive Model for chromatography with two components with the Langmuir adsorption isotherm. The coefficients estimated were Henry's coefficients, the total absorption capacity and the number of theoretical plates, while the design variables were the injection time and the initial concentration. The Bayesian OED algorithm is based on nested Monte Carlo estimation, which becomes computationally challenging due to the simulation time of the PDE involved in the dispersive model. This complication was relaxed by introducing a surrogate model based on Piecewise Sparse Linear Interpolation. Using the surrogate model instead the original reduces significantly the simulation time and it approximates the solution of the PDE with high degree of accuracy. The estimation of the parameters over strategical design points provided by OED reduces the uncertainty in the estimation of parameters. Additionally, the Bayesian OED methodology indicates no improvements when increasing the number of measurements in temporal nodes above a threshold value.

stat.AP↗

Stability estimates for the expected utility in Bayesian optimal experimental design

We study stability properties of the expected utility function in Bayesian optimal experimental design. We provide a framework for this problem in a non-parametric setting and prove a convergence rate of the expected utility with respect to a likelihood perturbation. This rate is uniform over the design space and its sharpness in the general setting is demonstrated by proving a lower bound in a special case. To make the problem more concrete we proceed by considering non-linear Bayesian inverse problems with Gaussian likelihood and prove that the assumptions set out for the general case are satisfied and regain the stability of the expected utility with respect to perturbations to the observation map. Theoretical convergence rates are demonstrated numerically in three different examples.

math.ST↗