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Joy T Wu

Publications and source records attributed to Joy T Wu.

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GazeXPErT: An Expert Eye-tracking Dataset for Interpretable and Explainable AI in Oncologic FDG-PET/CT Scans

[18F]FDG-PET/CT is a cornerstone imaging modality for guiding oncology therapies, yet human expert shortages necessitate more efficient diagnostic aids. While standalone AI models for automatic lesion detection exist, clinical translation remains hindered by AI explainability, reliability, and workflow integration. Meanwhile, human-computer-interaction in radiology remain limited to keyboard, mouse and voice, ignoring experts' faster, natural gaze signal. We present GazeXPErT, a 4D eye-tracking dataset with annotated expert decision windows for tumor detection and measurement on 346 dual-read FDG-PET/CTs. The dataset contributes 9,030 gaze-to-lesion trajectories derived from 3,948 minutes of 60 Hz eye-tracking data, rendered in COCO-style format. GazeXPErT captures experts' visual reasoning patterns when adjudicating suspicious lesions. It aims to facilitate development of trusted, explainable and interactive AI models through understanding expert gaze patterns. Baseline feasibility experiments suggest salient signal is extractable from routinely collected expert gaze (3D nnU-Net Dice: 0.6819 versus 0.6008 without), that gaze-trained vision transformers may aid dynamic lesion localization (74.95% predicted gaze closer to tumor), and that experts' intent may be predictable from raw gaze (Accuracy 67.53%, AUROC 0.747).

eess.IV

Age prediction using a large chest X-ray dataset

Age prediction based on appearances of different anatomies in medical images has been clinically explored for many decades. In this paper, we used deep learning to predict a persons age on Chest X-Rays. Specifically, we trained a CNN in regression fashion on a large publicly available dataset. Moreover, for interpretability, we explored activation maps to identify which areas of a CXR image are important for the machine (i.e. CNN) to predict a patients age, offering insight. Overall, amongst correctly predicted CXRs, we see areas near the clavicles, shoulders, spine, and mediastinum being most activated for age prediction, as one would expect biologically. Amongst incorrectly predicted CXRs, we have qualitatively identified disease patterns that could possibly make the anatomies appear older or younger than expected. A further technical and clinical evaluation would improve this work. As CXR is the most commonly requested imaging exam, a potential use case for estimating age may be found in the preventative counseling of patient health status compared to their age-expected average, particularly when there is a large discrepancy between predicted age and the real patient age.

cs.CV