arXiv subjects

Joyce Lee

Publications and source records attributed to Joyce Lee.

5 recordsLinked to original sources

arXiv2026

abx_amr_simulator: A simulation environment for antibiotic prescribing policy optimization under antimicrobial resistance

Antimicrobial resistance (AMR) poses a global health threat, reducing the effectiveness of antibiotics and complicating clinical decision-making. To address this challenge, we introduce abx_amr_simulator, a Python-based simulation package designed to model antibiotic prescribing and AMR dynamics within a controlled, reinforcement learning (RL)-compatible environment. The simulator allows users to specify patient populations, antibiotic-specific AMR response curves, and reward functions that balance immedi- ate clinical benefit against long-term resistance management. Key features include a modular design for configuring patient attributes, antibiotic resistance dynamics modeled via a leaky-balloon abstraction, and tools to explore partial observability through noise, bias, and delay in observations. The package is compatible with the Gymnasium RL API, enabling users to train and test RL agents under diverse clinical scenarios. From an ML perspective, the package provides a configurable benchmark environment for sequential decision-making under uncertainty, including partial observability induced by noisy, biased, and delayed observations. By providing a customizable and extensible framework, abx_amr_simulator offers a valuable tool for studying AMR dynamics and optimizing antibiotic stewardship strategies under realistic uncertainty.

cs.LG↗

arXiv2024

Finding Understanding and Support: Navigating Online Communities to Share and Connect at the intersection of Abuse and Foster Care Experiences

Many children in foster care experience trauma that is rooted in unstable family relationships. Other members of the foster care system like foster parents and social workers face secondary trauma. Drawing on 10 years of Reddit data, we used a mixed methods approach to analyze how different members of the foster care system find support and similar experiences at the intersection of two Reddit communities - foster care, and abuse. Users who cross this boundary focus on trauma experiences specific to different roles in foster care. While representing a small number of users, boundary crossing users contribute heavily to both communities, and, compared to matching users, receive higher scores and more replies. We explore the roles boundary crossing users have both in the online community and in the context of foster care. Finally, we present design recommendations that would support trauma survivors find communities more suited to their personal experiences.

cs.HC↗

arXiv2023

Forecasting with Sparse but Informative Variables: A Case Study in Predicting Blood Glucose

In time-series forecasting, future target values may be affected by both intrinsic and extrinsic effects. When forecasting blood glucose, for example, intrinsic effects can be inferred from the history of the target signal alone (\textit{i.e.} blood glucose), but accurately modeling the impact of extrinsic effects requires auxiliary signals, like the amount of carbohydrates ingested. Standard forecasting techniques often assume that extrinsic and intrinsic effects vary at similar rates. However, when auxiliary signals are generated at a much lower frequency than the target variable (e.g., blood glucose measurements are made every 5 minutes, while meals occur once every few hours), even well-known extrinsic effects (e.g., carbohydrates increase blood glucose) may prove difficult to learn. To better utilize these \textit{sparse but informative variables} (SIVs), we introduce a novel encoder/decoder forecasting approach that accurately learns the per-timepoint effect of the SIV, by (i) isolating it from intrinsic effects and (ii) restricting its learned effect based on domain knowledge. On a simulated dataset pertaining to the task of blood glucose forecasting, when the SIV is accurately recorded our approach outperforms baseline approaches in terms of rMSE (13.07 [95% CI: 11.77,14.16] vs. 14.14 [12.69,15.27]). In the presence of a corrupted SIV, the proposed approach can still result in lower error compared to the baseline but the advantage is reduced as noise increases. By isolating their effects and incorporating domain knowledge, our approach makes it possible to better utilize SIVs in forecasting.

cs.LG↗

arXiv2020

Deep Reinforcement Learning for Closed-Loop Blood Glucose Control

People with type 1 diabetes (T1D) lack the ability to produce the insulin their bodies need. As a result, they must continually make decisions about how much insulin to self-administer to adequately control their blood glucose levels. Longitudinal data streams captured from wearables, like continuous glucose monitors, can help these individuals manage their health, but currently the majority of the decision burden remains on the user. To relieve this burden, researchers are working on closed-loop solutions that combine a continuous glucose monitor and an insulin pump with a control algorithm in an `artificial pancreas.' Such systems aim to estimate and deliver the appropriate amount of insulin. Here, we develop reinforcement learning (RL) techniques for automated blood glucose control. Through a series of experiments, we compare the performance of different deep RL approaches to non-RL approaches. We highlight the flexibility of RL approaches, demonstrating how they can adapt to new individuals with little additional data. On over 2.1 million hours of data from 30 simulated patients, our RL approach outperforms baseline control algorithms: leading to a decrease in median glycemic risk of nearly 50% from 8.34 to 4.24 and a decrease in total time hypoglycemic of 99.8%, from 4,610 days to 6. Moreover, these approaches are able to adapt to predictable meal times (decreasing average risk by an additional 24% as meals increase in predictability). This work demonstrates the potential of deep RL to help people with T1D manage their blood glucose levels without requiring expert knowledge. All of our code is publicly available, allowing for replication and extension.

cs.LG↗

arXiv2020

A Risk Assessment of a Pretrial Risk Assessment Tool: Tussles, Mitigation Strategies, and Inherent Limits

We perform a risk assessment of the Public Safety Assessment (PSA), a software used in San Francisco and other jurisdictions to assist judges in deciding whether defendants need to be detained before their trial. With a mixed-methods approach including stakeholder interviews and the use of theoretical frameworks, we lay out the values at play as pretrial justice is automated. After identifying value implications of delegating decision making to technology, we articulate benefits and limitations of the PSA solution, as well as suggest mitigation strategies. We then draft the Handoff Tree, a novel algorithmic approach to pretrial justice that accommodates some of the inherent limitations of risk assessment tools by design. The model pairs every prediction with an associated error rate, and hands off the decision to the judge if the uncertainty is too high. By explicitly stating error rate, the Handoff Tree aims both to limit the impact of predictive disparity between race and gender, and to prompt judges to be more critical of retention recommendations, given the high rate of false positives they often entail.

cs.CY↗