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Juan Manuel Górriz

Publications and source records attributed to Juan Manuel Górriz.

6 recordsLinked to original sources

Exact analytical PGSE signal for diffusion confined to a cylindrical surface using a spectral Laplacian formalism

Objective. To derive an exact analytical expression for the diffusion MRI signal arising from diffusion confined to a cylindrical surface under finite rectangular pulsed-gradient spin-echo (PGSE) gradients, and to develop computationally efficient strategies for repeated model evaluations. Approach. The Bloch-Torrey equation was solved using a spectral matrix formalism of the Laplace operator in the eigenbasis of the cylindrical surface. The resulting signal is expressed as a product of non-commuting matrix exponentials and is valid for arbitrary rectangular gradient durations and separations, without approximations to the diffusion propagator or spin phase distribution. A reduced real spectral basis was introduced to decrease the dimensionality of the problem. Accelerated implementations based on Strang splitting and Gauss-Legendre quadrature were developed for repeated signal evaluations and computation of the spherical mean. The analytical signal was validated against Monte Carlo diffusion simulations. Main results. The exact formulation showed excellent agreement with Monte Carlo simulations over a wide range of cylinder radii and acquisition parameters. The spectral expansion converged rapidly with mode order, and the reduced basis substantially decreased computational cost without loss of accuracy. The accelerated implementations provided large additional speed-ups while retaining controllable errors relative to the exact solution. Significance. The proposed framework extends exact finite-pulse solutions of the Bloch-Torrey equation to diffusion confined to cylindrical surfaces and provides practical implementations for directional and orientationally averaged diffusion MRI signals. It therefore offers an approximation-free reference for assessing faster signal approximations and for applications requiring large numbers of model evaluations.

physics.med-ph↗

RESISTO Project: Safeguarding the Power Grid from Meteorological Phenomena

The RESISTO project, a pioneer innovation initiative in Europe, endeavors to enhance the resilience of electrical networks against extreme weather events and associated risks. Emphasizing intelligence and flexibility within distribution networks, RESISTO aims to address climatic and physical incidents comprehensively, fostering resilience across planning, response, recovery, and adaptation phases. Leveraging advanced technologies including AI, IoT sensors, and aerial robots, RESISTO integrates prediction, detection, and mitigation strategies to optimize network operation. This article summarizes the main technical aspects of the proposed solutions to meet the aforementioned objectives, including the development of a climate risk detection platform, an IoT-based monitoring and anomaly detection network, and a fleet of intelligent aerial robots. Each contributing to the project's overarching objectives of enhancing network resilience and operational efficiency.

cs.OH↗

RESISTO Project: Automatic detection of operation temperature anomalies for power electric transformers using thermal imaging

The RESISTO project represents a pioneering initiative in Europe aimed at enhancing the resilience of the power grid through the integration of advanced technologies. This includes artificial intelligence and thermal surveillance systems to mitigate the impact of extreme meteorological phenomena. RESISTO endeavors to predict, prevent, detect, and recover from weather-related incidents, ultimately enhancing the quality of service provided and ensuring grid stability and efficiency in the face of evolving climate challenges. In this study, we introduce one of the fundamental pillars of the project: a monitoring system for the operating temperature of different regions within power transformers, aiming to detect and alert early on potential thermal anomalies. To achieve this, a distributed system of thermal cameras for real-time temperature monitoring has been deployed in The Doñana National Park, alongside servers responsible for the storing, analyzing, and alerting of any potential thermal anomalies. An adaptive prediction model was developed for temperature forecasting, which learns online from the newly available data. In order to test the long-term performance of the proposed solution, we generated a synthetic temperature database for the whole of the year 2022. Overall, the proposed system exhibits promising capabilities in predicting and detecting thermal anomalies in power electric transformers, showcasing potential applications in enhancing grid reliability and preventing equipment failures.

eess.SY↗

EEG Connectivity Analysis Using Denoising Autoencoders for the Detection of Dyslexia

The Temporal Sampling Framework (TSF) theorizes that the characteristic phonological difficulties of dyslexia are caused by an atypical oscillatory sampling at one or more temporal rates. The LEEDUCA study conducted a series of Electroencephalography (EEG) experiments on children listening to amplitude modulated (AM) noise with slow-rythmic prosodic (0.5-1 Hz), syllabic (4-8 Hz) or the phoneme (12-40 Hz) rates, aimed at detecting differences in perception of oscillatory sampling that could be associated with dyslexia. The purpose of this work is to check whether these differences exist and how they are related to children's performance in different language and cognitive tasks commonly used to detect dyslexia. To this purpose, temporal and spectral inter-channel EEG connectivity was estimated, and a denoising autoencoder (DAE) was trained to learn a low-dimensional representation of the connectivity matrices. This representation was studied via correlation and classification analysis, which revealed ability in detecting dyslexic subjects with an accuracy higher than 0.8, and balanced accuracy around 0.7. Some features of the DAE representation were significantly correlated ($p<0.005$) with children's performance in language and cognitive tasks of the phonological hypothesis category such as phonological awareness and rapid symbolic naming, as well as reading efficiency and reading comprehension. Finally, a deeper analysis of the adjacency matrix revealed a reduced bilateral connection between electrodes of the temporal lobe (roughly the primary auditory cortex) in DD subjects, as well as an increased connectivity of the F7 electrode, placed roughly on Broca's area. These results pave the way for a complementary assessment of dyslexia using more objective methodologies such as EEG.

q-bio.NC↗

Deep Learning in current Neuroimaging: a multivariate approach with power and type I error control but arguable generalization ability

Discriminative analysis in neuroimaging by means of deep/machine learning techniques is usually tested with validation techniques, whereas the associated statistical significance remains largely under-developed due to their computational complexity. In this work, a non-parametric framework is proposed that estimates the statistical significance of classifications using deep learning architectures. In particular, a combination of autoencoders (AE) and support vector machines (SVM) is applied to: (i) a one-condition, within-group designs often of normal controls (NC) and; (ii) a two-condition, between-group designs which contrast, for example, Alzheimer's disease (AD) patients with NC (the extension to multi-class analyses is also included). A random-effects inference based on a label permutation test is proposed in both studies using cross-validation (CV) and resubstitution with upper bound correction (RUB) as validation methods. This allows both false positives and classifier overfitting to be detected as well as estimating the statistical power of the test. Several experiments were carried out using the Alzheimer's Disease Neuroimaging Initiative (ADNI) dataset, the Dominantly Inherited Alzheimer Network (DIAN) dataset, and a MCI prediction dataset. We found in the permutation test that CV and RUB methods offer a false positive rate close to the significance level and an acceptable statistical power (although lower using cross-validation). A large separation between training and test accuracies using CV was observed, especially in one-condition designs. This implies a low generalization ability as the model fitted in training is not informative with respect to the test set. We propose as solution by applying RUB, whereby similar results are obtained to those of the CV test set, but considering the whole set and with a lower computational cost per iteration.

stat.ML↗

Ensemble Deep Learning on Large, Mixed-Site fMRI Datasets in Autism and Other Tasks

Deep learning models for MRI classification face two recurring problems: they are typically limited by low sample size, and are abstracted by their own complexity (the "black box problem"). In this paper, we train a convolutional neural network (CNN) with the largest multi-source, functional MRI (fMRI) connectomic dataset ever compiled, consisting of 43,858 datapoints. We apply this model to a cross-sectional comparison of autism (ASD) vs typically developing (TD) controls that has proved difficult to characterise with inferential statistics. To contextualise these findings, we additionally perform classifications of gender and task vs rest. Employing class-balancing to build a training set, we trained 3$\times$300 modified CNNs in an ensemble model to classify fMRI connectivity matrices with overall AUROCs of 0.6774, 0.7680, and 0.9222 for ASD vs TD, gender, and task vs rest, respectively. Additionally, we aim to address the black box problem in this context using two visualization methods. First, class activation maps show which functional connections of the brain our models focus on when performing classification. Second, by analyzing maximal activations of the hidden layers, we were also able to explore how the model organizes a large and mixed-centre dataset, finding that it dedicates specific areas of its hidden layers to processing different covariates of data (depending on the independent variable analyzed), and other areas to mix data from different sources. Our study finds that deep learning models that distinguish ASD from TD controls focus broadly on temporal and cerebellar connections, with a particularly high focus on the right caudate nucleus and paracentral sulcus.

q-bio.QM↗