arXiv subjects

Jun Shen

Publications and source records attributed to Jun Shen.

At least 73 records · Page 4Linked to original sources

arXiv2023

In Vivo GABA Detection by Single Pulse Editing with One Shot

Over the past two decades, magnetic resonance spectroscopy with two-shot difference editing has been widely employed to characterize altered levels of GABA, the primary inhibitory neurotransmitter in the brain, in various neuropsychiatric disorders. This conventional technique detects the GABA H4 resonance, making it unsuitable for investigating GABA metabolism. It also suffers from subtraction artifacts, signal loss, and significant contamination by macromolecules. Here, we introduce a single-shot method for detecting GABA H2, effectively overcoming these difficulties. Since GABA turnover initiates at its protonated C2 and unprotonated C1 positions, we demonstrate, for the first time, noninvasive real-time monitoring of GABA metabolism in the human brain, utilizing GABA H2 as a highly sensitive reporter for GABA C2. This new method not only enhances the quantitative measurement of GABA levels but also opens up a new avenue to probe the metabolic processes underlying alterations in GABA levels in patients.

physics.med-ph↗

arXiv2023

DANAA: Towards transferable attacks with double adversarial neuron attribution

While deep neural networks have excellent results in many fields, they are susceptible to interference from attacking samples resulting in erroneous judgments. Feature-level attacks are one of the effective attack types, which targets the learnt features in the hidden layers to improve its transferability across different models. Yet it is observed that the transferability has been largely impacted by the neuron importance estimation results. In this paper, a double adversarial neuron attribution attack method, termed `DANAA', is proposed to obtain more accurate feature importance estimation. In our method, the model outputs are attributed to the middle layer based on an adversarial non-linear path. The goal is to measure the weight of individual neurons and retain the features that are more important towards transferability. We have conducted extensive experiments on the benchmark datasets to demonstrate the state-of-the-art performance of our method. Our code is available at: https://github.com/Davidjinzb/DANAA

cs.CV↗

arXiv2023

Hypergraph Convolutional Networks for Fine-grained ICU Patient Similarity Analysis and Risk Prediction

The Intensive Care Unit (ICU) is one of the most important parts of a hospital, which admits critically ill patients and provides continuous monitoring and treatment. Various patient outcome prediction methods have been attempted to assist healthcare professionals in clinical decision-making. Existing methods focus on measuring the similarity between patients using deep neural networks to capture the hidden feature structures. However, the higher-order relationships are ignored, such as patient characteristics (e.g., diagnosis codes) and their causal effects on downstream clinical predictions. In this paper, we propose a novel Hypergraph Convolutional Network that allows the representation of non-pairwise relationships among diagnosis codes in a hypergraph to capture the hidden feature structures so that fine-grained patient similarity can be calculated for personalized mortality risk prediction. Evaluation using a publicly available eICU Collaborative Research Database indicates that our method achieves superior performance over the state-of-the-art models on mortality risk prediction. Moreover, the results of several case studies demonstrated the effectiveness and robustness of the model decisions.

cs.LG↗

arXiv2023

A novel automatic wind power prediction framework based on multi-time scale and temporal attention mechanisms

Wind energy is a widely distributed, renewable, and environmentally friendly energy source that plays a crucial role in mitigating global warming and addressing energy shortages. Nevertheless, wind power generation is characterized by volatility, intermittence, and randomness, which hinder its ability to serve as a reliable power source for the grid. Accurate wind power forecasting is crucial for developing a new power system that heavily relies on renewable energy sources. However, traditional wind power forecasting systems primarily focus on ultra-short-term or short-term forecasts, limiting their ability to address the diverse adjustment requirements of the power system simultaneously. To overcome these challenges, We propose an automatic framework capable of forecasting wind power across multi-time scale. The framework based on the tree-structured Parzen estimator (TPE) and temporal fusion transformer (TFT) that can provide ultra-short-term, short-term and medium-term wind power forecasting power.Our approach employs the TFT for wind power forecasting and categorizes features based on their properties. Additionally, we introduce a generic algorithm to simultaneously fine-tune the hyperparameters of the decomposition method and model. We evaluate the performance of our framework by conducting ablation experiments using three commonly used decomposition algorithms and six state-of-the-art models for forecasting multi-time scale. The experimental results demonstrate that our proposed method considerably improves prediction accuracy on the public dataset Engie https://opendata-renewables.engie.com. Compared to the second-best state-of-the-art model, our approach exhibits a reduction of 31.75% and 28.74% in normalized mean absolute error (nMAE) for 24-hour forecasting, and 20.79% and 16.93% in nMAE for 48-hour forecasting, respectively.

cs.LG↗

arXiv2023

Radiomics-Informed Deep Learning for Classification of Atrial Fibrillation Sub-Types from Left-Atrium CT Volumes

Atrial Fibrillation (AF) is characterized by rapid, irregular heartbeats, and can lead to fatal complications such as heart failure. The disease is divided into two sub-types based on severity, which can be automatically classified through CT volumes for disease screening of severe cases. However, existing classification approaches rely on generic radiomic features that may not be optimal for the task, whilst deep learning methods tend to over-fit to the high-dimensional volume inputs. In this work, we propose a novel radiomics-informed deep-learning method, RIDL, that combines the advantages of deep learning and radiomic approaches to improve AF sub-type classification. Unlike existing hybrid techniques that mostly rely on naïve feature concatenation, we observe that radiomic feature selection methods can serve as an information prior, and propose supplementing low-level deep neural network (DNN) features with locally computed radiomic features. This reduces DNN over-fitting and allows local variations between radiomic features to be better captured. Furthermore, we ensure complementary information is learned by deep and radiomic features by designing a novel feature de-correlation loss. Combined, our method addresses the limitations of deep learning and radiomic approaches and outperforms state-of-the-art radiomic, deep learning, and hybrid approaches, achieving 86.9% AUC for the AF sub-type classification task. Code is available at https://github.com/xmed-lab/RIDL.

cs.CV↗

arXiv2023

The coupling effect between the environment and strategies drives the emergence of group cooperation

Introducing environmental feedback into evolutionary game theory has led to the development of eco-evolutionary games, which have gained popularity due to their ability to capture the intricate interplay between the environment and decision-making processes. However, current researches in this field focus on the study to macroscopic evolutionary dynamics in infinite populations. In this study, we propose a multi-agent computational model based on reinforcement learning to explore the coupled dynamics between strategies and the environment in finite populations from a bottom-up perspective. Our findings indicate that even in environments that favor defectors, high levels of group cooperation can emerge from self-interested individuals, highlighting the significant role of the coupling effect between the environment and strategies. Over time, the higher payoff of defection can be diluted due to environmental degradation, while cooperation can become the dominant strategy when positively reinforced by the environment. Remarkably, individuals can accurately detect the inflection point of the environment solely through rewards, when a reinforcing positive feedback loop are triggered, resulting in a rapid increase in agents' rewards and facilitating the establishment and maintenance of group cooperation. Our research provides a fresh perspective on understanding the emergence of group cooperation and sheds light on the underlying mechanisms involving individuals and the environment.

physics.bio-ph↗

arXiv2023

MedFMC: A Real-world Dataset and Benchmark For Foundation Model Adaptation in Medical Image Classification

Foundation models, often pre-trained with large-scale data, have achieved paramount success in jump-starting various vision and language applications. Recent advances further enable adapting foundation models in downstream tasks efficiently using only a few training samples, e.g., in-context learning. Yet, the application of such learning paradigms in medical image analysis remains scarce due to the shortage of publicly accessible data and benchmarks. In this paper, we aim at approaches adapting the foundation models for medical image classification and present a novel dataset and benchmark for the evaluation, i.e., examining the overall performance of accommodating the large-scale foundation models downstream on a set of diverse real-world clinical tasks. We collect five sets of medical imaging data from multiple institutes targeting a variety of real-world clinical tasks (22,349 images in total), i.e., thoracic diseases screening in X-rays, pathological lesion tissue screening, lesion detection in endoscopy images, neonatal jaundice evaluation, and diabetic retinopathy grading. Results of multiple baseline methods are demonstrated using the proposed dataset from both accuracy and cost-effective perspectives.

cs.CV↗

arXiv2023

Engineering Blockchain Based Software Systems: Foundations, Survey, and Future Directions

Many scientific and practical areas have shown increasing interest in reaping the benefits of blockchain technology to empower software systems. However, the unique characteristics and requirements associated with Blockchain Based Software (BBS) systems raise new challenges across the development lifecycle that entail an extensive improvement of conventional software engineering. This article presents a systematic literature review of the state-of-the-art in BBS engineering research from a software engineering perspective. We characterize BBS engineering from the theoretical foundations, processes, models, and roles and discuss a rich repertoire of key development activities, principles, challenges, and techniques. The focus and depth of this survey not only gives software engineering practitioners and researchers a consolidated body of knowledge about current BBS development but also underpins a starting point for further research in this field.

cs.SE↗

arXiv2023

In Vivo Magnetic Resonance Spectroscopy by J-Locked Chemical Shift Encoding for Determination of Neurochemical Concentration and Transverse Relaxation Time

Cell pathology in neuropsychiatric disorders has mainly been accessible by analyzing postmortem tissue samples. Although molecular transverse relaxation informs local cellular microenvironment via molecule-environment interactions, precise determination of the transverse relaxation times of molecules with scalar couplings (J), such as glutamate and glutamine, is difficult using current in vivo magnetic resonance spectroscopy (MRS) technologies, whose approach to measuring transverse relaxation has not changed for decades. We introduce an in vivo MRS technique that achieves chemical shift encoding with selectively locked J-couplings in each column of the acquired two-dimensional dataset, freeing up the entire row dimension for transverse relaxation encoding. This results in increased spectral resolution, minimized background signals, and markedly broadened dynamic range for transverse relaxation encoding. This technique enables determination of the transverse relaxation times of glutamate and glutamine in vivo with unprecedented high precision. Since glutamate predominantly resides in glutamatergic neurons and glutamine in glia in the brain, this noninvasive technique provides a way to probe cellular pathophysiology in neuropsychiatric disorders for characterizing disease progression and monitoring treatment response in a cell type-specific manner in vivo.

physics.med-ph↗

arXiv2023

Resilient Output Containment Control of Heterogeneous Multiagent Systems Against Composite Attacks: A Digital Twin Approach

This paper studies the distributed resilient output containment control of heterogeneous multiagent systems against composite attacks, including denial-of-services (DoS) attacks, false-data injection (FDI) attacks, camouflage attacks, and actuation attacks. Inspired by digital twins, a twin layer (TL) with higher security and privacy is used to decouple the above problem into two tasks: defense protocols against DoS attacks on TL and defense protocols against actuation attacks on cyber-physical layer (CPL). First, considering modeling errors of leader dynamics, we introduce distributed observers to reconstruct the leader dynamics for each follower on TL under DoS attacks. Second, distributed estimators are used to estimate follower states according to the reconstructed leader dynamics on the TL. Third, according to the reconstructed leader dynamics, we design decentralized solvers that calculate the output regulator equations on CPL. Fourth, decentralized adaptive attack-resilient control schemes that resist unbounded actuation attacks are provided on CPL. Furthermore, we apply the above control protocols to prove that the followers can achieve uniformly ultimately bounded (UUB) convergence, and the upper bound of the UUB convergence is determined explicitly. Finally, two simulation examples are provided to show the effectiveness of the proposed control protocols.

eess.SY↗

arXiv2023

User Pairing and Power Allocation in Untrusted Multiuser NOMA for Internet-of-Things

In the Internet-of-Things (IoT), massive sensitive and confidential information is transmitted wirelessly, making security a serious concern. This is particularly true when technologies, such as non-orthogonal multiple access (NOMA), are used, making it possible for users to access each other's data. This paper studies secure communications in multiuser NOMA downlink systems, where each user is potentially an eavesdropper. Resource allocation is formulated to achieve the maximum sum secrecy rate, meanwhile satisfying the users' data requirements and power constraint. We solve this non-trivial, mixed-integer non-linear programming problem by decomposing it into power allocation with a closed-form solution, and user pairing obtained effectively using linear programming relaxation and barrier algorithm. These subproblems are solved iteratively until convergence, with the convergence rate rigorously analyzed. Simulations demonstrate that our approach outperforms its existing alternatives significantly in the sum secrecy rate and computational complexity.

cs.IT↗

arXiv2023

Dipolar Spin Liquid Ending with Quantum Critical Point in a Gd-based Triangular Magnet

By performing experiment and model studies on a triangular-lattice dipolar magnet KBaGd(BO$_3$)$_2$ (KBGB), we find the highly frustrated magnet with a planar anisotropy hosts a strongly fluctuating dipolar spin liquid (DSL), which originates from the intriguing interplay between dipolar and Heisenberg interactions. The DSL constitutes an extended regime in the field-temperature phase diagram, which gets lowered in temperature as field increases and eventually ends with an unconventional quantum critical point (QCP) at $B_c\simeq 0.75$~T. Based on dipolar Heisenberg model calculations, we identify the DSL as a Berezinskii-Kosterlitz-Thouless (BKT) phase with emergent U(1) symmetry. Due to the tremendous entropy accumulation that can be related to the strong BKT and quantum fluctuations, unprecedented magnetic cooling effects are observed in the DSL regime and particularly near the QCP, making KBGB a superior dipolar coolant to commercial Gd-based refrigerants. We establish the phase diagram for triangular-lattice dipolar quantum magnets where emergent symmetry plays an essential role, and provide a basis and opens an avenue for their applications in sub-Kelvin refrigeration.

cond-mat.str-el↗

arXiv2022

Benchmarking the Semi-Stochastic CC(P;Q) Approach for Singlet-Triplet Gaps in Biradicals

We recently proposed a semi-stochastic approach to converging high-level coupled-cluster (CC) energetics, such as those obtained in the CC calculations with singles, doubles, and triples (CCSDT), in which the deterministic CC($P$;$Q$) framework is merged with the stochastic configuration interaction Quantum Monte Carlo propagations [J. E. Deustua, J. Shen, and P. Piecuch, Phys. Rev. Lett. 119, 223003 (2017)]. In this work, we investigate the ability of the semi-stochastic CC($P$;$Q$) methodology to recover the CCSDT energies of the lowest singlet and triplet states and the corresponding singlet-triplet gaps of biradical systems using methylene, ${\rm (HFH)}^{-}$, cyclobutadiene, cyclopentadienyl cation, and trimethylenemethane as examples.

physics.chem-ph↗

arXiv2022

Expression might be enough: representing pressure and demand for reinforcement learning based traffic signal control

Many studies confirmed that a proper traffic state representation is more important than complex algorithms for the classical traffic signal control (TSC) problem. In this paper, we (1) present a novel, flexible and efficient method, namely advanced max pressure (Advanced-MP), taking both running and queuing vehicles into consideration to decide whether to change current signal phase; (2) inventively design the traffic movement representation with the efficient pressure and effective running vehicles from Advanced-MP, namely advanced traffic state (ATS); and (3) develop a reinforcement learning (RL) based algorithm template, called Advanced-XLight, by combining ATS with the latest RL approaches, and generate two RL algorithms, namely "Advanced-MPLight" and "Advanced-CoLight" from Advanced-XLight. Comprehensive experiments on multiple real-world datasets show that: (1) the Advanced-MP outperforms baseline methods, and it is also efficient and reliable for deployment; and (2) Advanced-MPLight and Advanced-CoLight can achieve the state-of-the-art.

cs.AI↗

arXiv2022

Crop and weed classification based on AutoML

CNN models already play an important role in classification of crop and weed with high accuracy, more than 95% as reported in literature. However, to manually choose and fine-tune the deep learning models becomes laborious and indispensable in most traditional practices and research. Moreover, the classic objective functions are not thoroughly compatible with agricultural farming tasks as the corresponding models suffer from misclassifying crop to weed, often more likely than in other deep learning application domains. In this paper, we applied autonomous machine learning with a new objective function for crop and weed classification, achieving higher accuracy and lower crop killing rate (rate of identifying a crop as a weed). The experimental results show that our method outperforms state-of-the-art applications, for example, ResNet and VGG19.

cs.AI↗

arXiv2022

Knowledge Management for Cloud Computing Field

Migration legacy systems to cloud platforms is a knowledge intensive process. There is an ever increasing body of knowledge reporting empirical scenarios of successful and problematic cloud migration. Reusing this body of knowledge, dispersed and fragmented over the academic/multi-vocal literature, has practical values to mitigate costly risks and pitfalls in further projects of legacy to-cloud and cloud-to-cloud migration. In line with this, knowledge management systems/platforms pertinent to cloud migration are a prime prerequisite and a strategic imperative for an organization. We have conducted a qualitative exploratory study to understand the benefits and challenges of developing Knowledge Management Systems (KMS) for cloud migration in real trials. Whilst our prototype system demonstration supported the importance and bene-fits of developing Cloud Migration KMS (CM-KMS), our semi-structured industry interview study with 11 participants highlighted challenging impediments against developing this class of KMS. As a result, this study proposes nine significant challenges that cause the abandon of the design and maintenance of CM-KMS, including continuous changes and updates, integration of knowledge, knowledge granularity, preservation of context, automation, deconstruction of traditional knowledge, dependency on experts, hybrid knowledge of both vendor-specific and vendor-neutral cloud platforms, and parsimony. Our results inform cloud architects to pay attention to adopt CM-KMS for the legacy-to-cloud migration in their organizations.

cs.SE↗

arXiv2021

Blockchain Developments and Innovations

Blockchain has received expanding interest from various domains. Institutions, enterprises, governments, and agencies are interested in Blockchain potential to augment their software systems. The unique requirements and characteristics of Blockchain platforms raise new challenges involving extensive enhancement to conventional software development processes to meet the needs of these domains. Software engineering approaches supporting Blockchain-oriented developments have been slow to materialize, despite proposals in the literature, and they have yet to be objectively analyzed. A critical appraisal of these innovations is crucial to identify their respective strengths and weaknesses. We present an analytical evaluation of several prominent Blockchain-oriented methods through a comprehensive, criteria-based evaluation framework. The results can be used for comparing, adapting, and developing a new generation of Blockchain-oriented software development processes and innovations.

cs.SE↗

arXiv2021

Efficient Pressure: Improving efficiency for signalized intersections

Since conventional approaches could not adapt to dynamic traffic conditions, reinforcement learning (RL) has attracted more attention to help solve the traffic signal control (TSC) problem. However, existing RL-based methods are rarely deployed considering that they are neither cost-effective in terms of computing resources nor more robust than traditional approaches, which raises a critical research question: how to construct an adaptive controller for TSC with less training and reduced complexity based on RL-based approach? To address this question, in this paper, we (1) innovatively specify the traffic movement representation as a simple but efficient pressure of vehicle queues in a traffic network, namely efficient pressure (EP); (2) build a traffic signal settings protocol, including phase duration, signal phase number and EP for TSC; (3) design a TSC approach based on the traditional max pressure (MP) approach, namely efficient max pressure (Efficient-MP) using the EP to capture the traffic state; and (4) develop a general RL-based TSC algorithm template: efficient Xlight (Efficient-XLight) under EP. Through comprehensive experiments on multiple real-world datasets in our traffic signal settings' protocol for TSC, we demonstrate that efficient pressure is complementary to traditional and RL-based modeling to design better TSC methods. Our code is released on Github.

cs.LG↗