arXiv subjects

Junhao Jia

Publications and source records attributed to Junhao Jia.

10 recordsLinked to original sources

arXiv2026

Beyond the Individual: Virtualizing Multi-Disciplinary Reasoning for Clinical Intake via Collaborative Agents

The initial outpatient consultation is critical for clinical decision-making, yet it is often conducted by a single physician under time pressure, making it prone to cognitive biases and incomplete evidence capture. Although the Multi-Disciplinary Team (MDT) reduces these risks, they are costly and difficult to scale to real-time intake. We propose Aegle, a synchronous virtual MDT framework that brings MDT-level reasoning to outpatient consultations via a graph-based multi-agent architecture. Aegle formalizes the consultation state using a structured SOAP representation, separating evidence collection from diagnostic reasoning to improve traceability and bias control. An orchestrator dynamically activates specialist agents, which perform decoupled parallel reasoning and are subsequently integrated by an aggregator into a coherent clinical note. Experiments on ClinicalBench and a real-world RAPID-IPN dataset across 24 departments and 53 metrics show that Aegle consistently outperforms state-of-the-art proprietary and open-source models in documentation quality and consultation capability, while also improving final diagnosis accuracy. Our code is available at https://github.com/HovChen/Aegle.

cs.MA↗

arXiv2026

Sci-Mind: Cognitively-Inspired Adversarial Debate for Autonomous Mathematical Modeling

Real-world mathematical modeling is inherently an experiential and collaborative endeavor. Domain experts rarely solve complex problems from scratch; instead, they draw upon analogies from historical cases and subject their hypotheses to rigorous peer scrutiny. However, autonomous agents powered by Large Language Models predominantly rely on isolated reasoning paradigms, frequently generating plausible but fundamentally flawed models due to a lack of domain grounding and adversarial verification. To address these limitations, we propose Sci-Mind, a novel framework that mirrors the human scientific discovery process. Sci-Mind integrates Experiential Memory Recall to retrieve executable code snippets and modeling paradigm descriptors, grounding abstract reasoning in historical solutions. Subsequently, it employs an Adversarial Cognitive Dialectic where a Theorist optimizing mathematical coherence and a Pragmatist enforcing data feasibility debate through competing objectives to prune elegant but infeasible formulations. A Self-Validating Execution Strategy further ensures blueprint consistency through formal predicates before code generation, achieving fully autonomous execution. Extensive experiments on the MM-Bench and EngiBench demonstrate that Sci-Mind significantly outperforms leading autonomous agents in both modeling rigorousness and code executability.

cs.MA↗

arXiv2026

This Looks Distinctly Like That: Grounding Interpretable Recognition in Stiefel Geometry against Neural Collapse

Prototype networks provide an intrinsic case based explanation mechanism, but their interpretability is often undermined by prototype collapse, where multiple prototypes degenerate to highly redundant evidence. We attribute this failure mode to the terminal dynamics of Neural Collapse, where cross entropy optimization suppresses intra class variance and drives class conditional features toward a low dimensional limit. To mitigate this, we propose Adaptive Manifold Prototypes (AMP), a framework that leverages Riemannian optimization on the Stiefel manifold to represent class prototypes as orthonormal bases and make rank one prototype collapse infeasible by construction. AMP further learns class specific effective rank via a proximal gradient update on a nonnegative capacity vector, and introduces spatial regularizers that reduce rotational ambiguity and encourage localized, non overlapping part evidence. Extensive experiments on fine-grained benchmarks demonstrate that AMP achieves state-of-the-art classification accuracy while significantly improving causal faithfulness over prior interpretable models.

cs.CV↗

arXiv2026

Unsupervised Causal Prototypical Networks for De-biased Interpretable Dermoscopy Diagnosis

Despite the success of deep learning in dermoscopy image analysis, its inherent black-box nature hinders clinical trust, motivating the use of prototypical networks for case-based visual transparency. However, inevitable selection bias in clinical data often drives these models toward shortcut learning, where environmental confounders are erroneously encoded as predictive prototypes, generating spurious visual evidence that misleads medical decision-making. To mitigate these confounding effects, we propose CausalProto, an Unsupervised Causal Prototypical Network that fundamentally purifies the visual evidence chain. Framed within a Structural Causal Model, we employ an Information Bottleneck-constrained encoder to enforce strict unsupervised orthogonal disentanglement between pathological features and environmental confounders. By mapping these decoupled representations into independent prototypical spaces, we leverage the learned spurious dictionary to perform backdoor adjustment via do-calculus, transforming complex causal interventions into efficient expectation pooling to marginalize environmental noise. Extensive experiments on multiple dermoscopy datasets demonstrate that CausalProto achieves superior diagnostic performance and consistently outperforms standard black box models, while simultaneously providing transparent and high purity visual interpretability without suffering from the traditional accuracy compromise.

eess.IV↗

arXiv2026

Directed Ordinal Diffusion Regularization for Progression-Aware Diabetic Retinopathy Grading

Diabetic Retinopathy (DR) progresses as a continuous and irreversible deterioration of the retina, following a well-defined clinical trajectory from mild to severe stages. However, most existing ordinal regression approaches model DR severity as a set of static, symmetric ranks, capturing relative order while ignoring the inherent unidirectional nature of disease progression. As a result, the learned feature representations may violate biological plausibility, allowing implausible proximity between non-consecutive stages or even reverse transitions. To bridge this gap, we propose Directed Ordinal Diffusion Regularization (D-ODR), which explicitly models the feature space as a directed flow by constructing a progression-constrained directed graph that strictly enforces forward disease evolution. By performing multi-scale diffusion on this directed structure, D-ODR imposes penalties on score inversions along valid progression paths, thereby effectively preventing the model from learning biologically inconsistent reverse transitions. This mechanism aligns the feature representation with the natural trajectory of DR worsening. Extensive experiments demonstrate that D-ODR yields superior grading performance compared to state-of-the-art ordinal regression and DR-specific grading methods, offering a more clinically reliable assessment of disease severity. Our code is available on https://github.com/HovChen/D-ODR.

cs.CV↗

arXiv2025

WDT-MD: Wavelet Diffusion Transformers for Microaneurysm Detection in Fundus Images

Microaneurysms (MAs), the earliest pathognomonic signs of Diabetic Retinopathy (DR), present as sub-60 $\mu m$ lesions in fundus images with highly variable photometric and morphological characteristics, rendering manual screening not only labor-intensive but inherently error-prone. While diffusion-based anomaly detection has emerged as a promising approach for automated MA screening, its clinical application is hindered by three fundamental limitations. First, these models often fall prey to "identity mapping", where they inadvertently replicate the input image. Second, they struggle to distinguish MAs from other anomalies, leading to high false positives. Third, their suboptimal reconstruction of normal features hampers overall performance. To address these challenges, we propose a Wavelet Diffusion Transformer framework for MA Detection (WDT-MD), which features three key innovations: a noise-encoded image conditioning mechanism to avoid "identity mapping" by perturbing image conditions during training; pseudo-normal pattern synthesis via inpainting to introduce pixel-level supervision, enabling discrimination between MAs and other anomalies; and a wavelet diffusion Transformer architecture that combines the global modeling capability of diffusion Transformers with multi-scale wavelet analysis to enhance reconstruction of normal retinal features. Comprehensive experiments on the IDRiD and e-ophtha MA datasets demonstrate that WDT-MD outperforms state-of-the-art methods in both pixel-level and image-level MA detection. This advancement holds significant promise for improving early DR screening.

cs.CV↗

arXiv2025

Geodesic Prototype Matching via Diffusion Maps for Interpretable Fine-Grained Recognition

Nonlinear manifolds are pervasive in deep visual features, where Euclidean distances can misrepresent true similarity. This mismatch is particularly detrimental to prototype-based interpretable fine-grained recognition, where even subtle semantic distinctions are crucial. To mitigate this issue, this work presents a novel paradigm for prototype-based recognition by grounding similarity in the intrinsic geometry of deep features. Concretely, we distill the latent manifold structure of each class into a diffusion space and, critically, devise a differentiable Nystr\"{o}m interpolation to make this geometry accessible to both unseen samples and learnable prototypes. To maintain efficiency, we employ compact per-class landmark sets with periodic updates. This strategy keeps the embedding synchronized with the evolving backbone, enabling fast inference at scale. Comprehensive experiments on two benchmark datasets demonstrate that our GeoProto yields prototypes focusing on semantically corresponding parts, significantly outperforming Euclidean prototype networks.

cs.CV↗

arXiv2025

Brain-HGCN: A Hyperbolic Graph Convolutional Network for Brain Functional Network Analysis

Functional magnetic resonance imaging (fMRI) reveals complex brain functional networks with hierarchical topologies crucial for cognitive processing. Standard Euclidean Graph Neural Networks (GNNs) often struggle to represent these hierarchical structures without high distortion due to inherent spatial constraints. We propose Brain-HGCN, a geometric deep learning framework based on hyperbolic geometry, which leverages negatively curved space to model brain network hierarchy with high fidelity. Grounded in the Lorentz model, our framework employs a novel hyperbolic graph attention layer with a signed aggregation mechanism to distinctly process excitatory and inhibitory connections. Furthermore, we learn robust graph-level representations via a geometrically principled Fr\'echet mean for graph readout. Experiments on two large-scale fMRI datasets for psychiatric disorder classification demonstrate that Brain-HGCN significantly outperforms state-of-the-art Euclidean baselines. This work highlights the potential of hyperbolic GNNs in computational psychiatry by pioneering a new geometric paradigm for fMRI analysis.

cs.CV↗

arXiv2025

RTGMFF: Enhanced fMRI-based Brain Disorder Diagnosis via ROI-driven Text Generation and Multimodal Feature Fusion

Functional magnetic resonance imaging (fMRI) is a powerful tool for probing brain function, yet reliable clinical diagnosis is hampered by low signal-to-noise ratios, inter-subject variability, and the limited frequency awareness of prevailing CNN- and Transformer-based models. Moreover, most fMRI datasets lack textual annotations that could contextualize regional activation and connectivity patterns. We introduce RTGMFF, a framework that unifies automatic ROI-level text generation with multimodal feature fusion for brain-disorder diagnosis. RTGMFF consists of three components: (i) ROI-driven fMRI text generation deterministically condenses each subject's activation, connectivity, age, and sex into reproducible text tokens; (ii) Hybrid frequency-spatial encoder fuses a hierarchical wavelet-mamba branch with a cross-scale Transformer encoder to capture frequency-domain structure alongside long-range spatial dependencies; and (iii) Adaptive semantic alignment module embeds the ROI token sequence and visual features in a shared space, using a regularized cosine-similarity loss to narrow the modality gap. Extensive experiments on the ADHD-200 and ABIDE benchmarks show that RTGMFF surpasses current methods in diagnostic accuracy, achieving notable gains in sensitivity, specificity, and area under the ROC curve. Code is available at https://github.com/BeistMedAI/RTGMFF.

cs.CV↗

arXiv2024

TC-KANRecon: High-Quality and Accelerated MRI Reconstruction via Adaptive KAN Mechanisms and Intelligent Feature Scaling

Magnetic Resonance Imaging (MRI) has become essential in clinical diagnosis due to its high resolution and multiple contrast mechanisms. However, the relatively long acquisition time limits its broader application. To address this issue, this study presents an innovative conditional guided diffusion model, named as TC-KANRecon, which incorporates the Multi-Free U-KAN (MF-UKAN) module and a dynamic clipping strategy. TC-KANRecon model aims to accelerate the MRI reconstruction process through deep learning methods while maintaining the quality of the reconstructed images. The MF-UKAN module can effectively balance the tradeoff between image denoising and structure preservation. Specifically, it presents the multi-head attention mechanisms and scalar modulation factors, which significantly enhances the model's robustness and structure preservation capabilities in complex noise environments. Moreover, the dynamic clipping strategy in TC-KANRecon adjusts the cropping interval according to the sampling steps, thereby mitigating image detail loss typicalching the visual features of the images. Furthermore, the MC-Model incorporates full-sampling k-space information, realizing efficient fusion of conditional information, enhancing the model's ability to process complex data, and improving the realism and detail richness of reconstructed images. Experimental results demonstrate that the proposed method outperforms other MRI reconstruction methods in both qualitative and quantitative evaluations. Notably, TC-KANRecon method exhibits excellent reconstruction results when processing high-noise, low-sampling-rate MRI data. Our source code is available at https://github.com/lcbkmm/TC-KANRecon.

eess.IV↗