arXiv subjects

Junjun He

Publications and source records attributed to Junjun He.

121 records · Page 7Linked to original sources

arXiv2023

Vision Transformer Adapter for Dense Predictions

This work investigates a simple yet powerful dense prediction task adapter for Vision Transformer (ViT). Unlike recently advanced variants that incorporate vision-specific inductive biases into their architectures, the plain ViT suffers inferior performance on dense predictions due to weak prior assumptions. To address this issue, we propose the ViT-Adapter, which allows plain ViT to achieve comparable performance to vision-specific transformers. Specifically, the backbone in our framework is a plain ViT that can learn powerful representations from large-scale multi-modal data. When transferring to downstream tasks, a pre-training-free adapter is used to introduce the image-related inductive biases into the model, making it suitable for these tasks. We verify ViT-Adapter on multiple dense prediction tasks, including object detection, instance segmentation, and semantic segmentation. Notably, without using extra detection data, our ViT-Adapter-L yields state-of-the-art 60.9 box AP and 53.0 mask AP on COCO test-dev. We hope that the ViT-Adapter could serve as an alternative for vision-specific transformers and facilitate future research. The code and models will be released at https://github.com/czczup/ViT-Adapter.

cs.CV↗

arXiv2022

Exploring Vanilla U-Net for Lesion Segmentation from Whole-body FDG-PET/CT Scans

Tumor lesion segmentation is one of the most important tasks in medical image analysis. In clinical practice, Fluorodeoxyglucose Positron-Emission Tomography~(FDG-PET) is a widely used technique to identify and quantify metabolically active tumors. However, since FDG-PET scans only provide metabolic information, healthy tissue or benign disease with irregular glucose consumption may be mistaken for cancer. To handle this challenge, PET is commonly combined with Computed Tomography~(CT), with the CT used to obtain the anatomic structure of the patient. The combination of PET-based metabolic and CT-based anatomic information can contribute to better tumor segmentation results. %Computed tomography~(CT) is a popular modality to illustrate the anatomic structure of the patient. The combination of PET and CT is promising to handle this challenge by utilizing metabolic and anatomic information. In this paper, we explore the potential of U-Net for lesion segmentation in whole-body FDG-PET/CT scans from three aspects, including network architecture, data preprocessing, and data augmentation. The experimental results demonstrate that the vanilla U-Net with proper input shape can achieve satisfactory performance. Specifically, our method achieves first place in both preliminary and final leaderboards of the autoPET 2022 challenge. Our code is available at https://github.com/Yejin0111/autoPET2022_Blackbean.

eess.IV↗

arXiv2022

An evaluation of U-Net in Renal Structure Segmentation

Renal structure segmentation from computed tomography angiography~(CTA) is essential for many computer-assisted renal cancer treatment applications. Kidney PArsing~(KiPA 2022) Challenge aims to build a fine-grained multi-structure dataset and improve the segmentation of multiple renal structures. Recently, U-Net has dominated the medical image segmentation. In the KiPA challenge, we evaluated several U-Net variants and selected the best models for the final submission.

eess.IV↗

arXiv2022

Dynamic Instance Domain Adaptation

Most existing studies on unsupervised domain adaptation (UDA) assume that each domain's training samples come with domain labels (e.g., painting, photo). Samples from each domain are assumed to follow the same distribution and the domain labels are exploited to learn domain-invariant features via feature alignment. However, such an assumption often does not hold true -- there often exist numerous finer-grained domains (e.g., dozens of modern painting styles have been developed, each differing dramatically from those of the classic styles). Therefore, forcing feature distribution alignment across each artificially-defined and coarse-grained domain can be ineffective. In this paper, we address both single-source and multi-source UDA from a completely different perspective, which is to view each instance as a fine domain. Feature alignment across domains is thus redundant. Instead, we propose to perform dynamic instance domain adaptation (DIDA). Concretely, a dynamic neural network with adaptive convolutional kernels is developed to generate instance-adaptive residuals to adapt domain-agnostic deep features to each individual instance. This enables a shared classifier to be applied to both source and target domain data without relying on any domain annotation. Further, instead of imposing intricate feature alignment losses, we adopt a simple semi-supervised learning paradigm using only a cross-entropy loss for both labeled source and pseudo labeled target data. Our model, dubbed DIDA-Net, achieves state-of-the-art performance on several commonly used single-source and multi-source UDA datasets including Digits, Office-Home, DomainNet, Digit-Five, and PACS.

cs.CV↗

arXiv2022

OpenKBP-Opt: An international and reproducible evaluation of 76 knowledge-based planning pipelines

We establish an open framework for developing plan optimization models for knowledge-based planning (KBP) in radiotherapy. Our framework includes reference plans for 100 patients with head-and-neck cancer and high-quality dose predictions from 19 KBP models that were developed by different research groups during the OpenKBP Grand Challenge. The dose predictions were input to four optimization models to form 76 unique KBP pipelines that generated 7600 plans. The predictions and plans were compared to the reference plans via: dose score, which is the average mean absolute voxel-by-voxel difference in dose a model achieved; the deviation in dose-volume histogram (DVH) criterion; and the frequency of clinical planning criteria satisfaction. We also performed a theoretical investigation to justify our dose mimicking models. The range in rank order correlation of the dose score between predictions and their KBP pipelines was 0.50 to 0.62, which indicates that the quality of the predictions is generally positively correlated with the quality of the plans. Additionally, compared to the input predictions, the KBP-generated plans performed significantly better (P<0.05; one-sided Wilcoxon test) on 18 of 23 DVH criteria. Similarly, each optimization model generated plans that satisfied a higher percentage of criteria than the reference plans. Lastly, our theoretical investigation demonstrated that the dose mimicking models generated plans that are also optimal for a conventional planning model. This was the largest international effort to date for evaluating the combination of KBP prediction and optimization models. In the interest of reproducibility, our data and code is freely available at https://github.com/ababier/open-kbp-opt.

physics.med-ph↗

arXiv2021

Group Shift Pointwise Convolution for Volumetric Medical Image Segmentation

Recent studies have witnessed the effectiveness of 3D convolutions on segmenting volumetric medical images. Compared with the 2D counterparts, 3D convolutions can capture the spatial context in three dimensions. Nevertheless, models employing 3D convolutions introduce more trainable parameters and are more computationally complex, which may lead easily to model overfitting especially for medical applications with limited available training data. This paper aims to improve the effectiveness and efficiency of 3D convolutions by introducing a novel Group Shift Pointwise Convolution (GSP-Conv). GSP-Conv simplifies 3D convolutions into pointwise ones with 1x1x1 kernels, which dramatically reduces the number of model parameters and FLOPs (e.g. 27x fewer than 3D convolutions with 3x3x3 kernels). Naïve pointwise convolutions with limited receptive fields cannot make full use of the spatial image context. To address this problem, we propose a parameter-free operation, Group Shift (GS), which shifts the feature maps along with different spatial directions in an elegant way. With GS, pointwise convolutions can access features from different spatial locations, and the limited receptive fields of pointwise convolutions can be compensated. We evaluate the proposed methods on two datasets, PROMISE12 and BraTS18. Results show that our method, with substantially decreased model complexity, achieves comparable or even better performance than models employing 3D convolutions.

eess.IV↗

arXiv2021

A Novel Hybrid Convolutional Neural Network for Accurate Organ Segmentation in 3D Head and Neck CT Images

Radiation therapy (RT) is widely employed in the clinic for the treatment of head and neck (HaN) cancers. An essential step of RT planning is the accurate segmentation of various organs-at-risks (OARs) in HaN CT images. Nevertheless, segmenting OARs manually is time-consuming, tedious, and error-prone considering that typical HaN CT images contain tens to hundreds of slices. Automated segmentation algorithms are urgently required. Recently, convolutional neural networks (CNNs) have been extensively investigated on this task. Particularly, 3D CNNs are frequently adopted to process 3D HaN CT images. There are two issues with naïve 3D CNNs. First, the depth resolution of 3D CT images is usually several times lower than the in-plane resolution. Direct employment of 3D CNNs without distinguishing this difference can lead to the extraction of distorted image features and influence the final segmentation performance. Second, a severe class imbalance problem exists, and large organs can be orders of times larger than small organs. It is difficult to simultaneously achieve accurate segmentation for all the organs. To address these issues, we propose a novel hybrid CNN that fuses 2D and 3D convolutions to combat the different spatial resolutions and extract effective edge and semantic features from 3D HaN CT images. To accommodate large and small organs, our final model, named OrganNet2.5D, consists of only two instead of the classic four downsampling operations, and hybrid dilated convolutions are introduced to maintain the respective field. Experiments on the MICCAI 2015 challenge dataset demonstrate that OrganNet2.5D achieves promising performance compared to state-of-the-art methods.

eess.IV↗

arXiv2020

Attention-Driven Dynamic Graph Convolutional Network for Multi-Label Image Recognition

Recent studies often exploit Graph Convolutional Network (GCN) to model label dependencies to improve recognition accuracy for multi-label image recognition. However, constructing a graph by counting the label co-occurrence possibilities of the training data may degrade model generalizability, especially when there exist occasional co-occurrence objects in test images. Our goal is to eliminate such bias and enhance the robustness of the learnt features. To this end, we propose an Attention-Driven Dynamic Graph Convolutional Network (ADD-GCN) to dynamically generate a specific graph for each image. ADD-GCN adopts a Dynamic Graph Convolutional Network (D-GCN) to model the relation of content-aware category representations that are generated by a Semantic Attention Module (SAM). Extensive experiments on public multi-label benchmarks demonstrate the effectiveness of our method, which achieves mAPs of 85.2%, 96.0%, and 95.5% on MS-COCO, VOC2007, and VOC2012, respectively, and outperforms current state-of-the-art methods with a clear margin. All codes can be found at https://github.com/Yejin0111/ADD-GCN.

cs.CV↗

arXiv2020

MIA-Prognosis: A Deep Learning Framework to Predict Therapy Response

Predicting clinical outcome is remarkably important but challenging. Research efforts have been paid on seeking significant biomarkers associated with the therapy response or/and patient survival. However, these biomarkers are generally costly and invasive, and possibly dissatifactory for novel therapy. On the other hand, multi-modal, heterogeneous, unaligned temporal data is continuously generated in clinical practice. This paper aims at a unified deep learning approach to predict patient prognosis and therapy response, with easily accessible data, e.g., radiographics, laboratory and clinical information. Prior arts focus on modeling single data modality, or ignore the temporal changes. Importantly, the clinical time series is asynchronous in practice, i.e., recorded with irregular intervals. In this study, we formalize the prognosis modeling as a multi-modal asynchronous time series classification task, and propose a MIA-Prognosis framework with Measurement, Intervention and Assessment (MIA) information to predict therapy response, where a Simple Temporal Attention (SimTA) module is developed to process the asynchronous time series. Experiments on synthetic dataset validate the superiory of SimTA over standard RNN-based approaches. Furthermore, we experiment the proposed method on an in-house, retrospective dataset of real-world non-small cell lung cancer patients under anti-PD-1 immunotherapy. The proposed method achieves promising performance on predicting the immunotherapy response. Notably, our predictive model could further stratify low-risk and high-risk patients in terms of long-term survival.

cs.LG↗

arXiv2020

EfficientFCN: Holistically-guided Decoding for Semantic Segmentation

Both performance and efficiency are important to semantic segmentation. State-of-the-art semantic segmentation algorithms are mostly based on dilated Fully Convolutional Networks (dilatedFCN), which adopt dilated convolutions in the backbone networks to extract high-resolution feature maps for achieving high-performance segmentation performance. However, due to many convolution operations are conducted on the high-resolution feature maps, such dilatedFCN-based methods result in large computational complexity and memory consumption. To balance the performance and efficiency, there also exist encoder-decoder structures that gradually recover the spatial information by combining multi-level feature maps from the encoder. However, the performances of existing encoder-decoder methods are far from comparable with the dilatedFCN-based methods. In this paper, we propose the EfficientFCN, whose backbone is a common ImageNet pre-trained network without any dilated convolution. A holistically-guided decoder is introduced to obtain the high-resolution semantic-rich feature maps via the multi-scale features from the encoder. The decoding task is converted to novel codebook generation and codeword assembly task, which takes advantages of the high-level and low-level features from the encoder. Such a framework achieves comparable or even better performance than state-of-the-art methods with only 1/3 of the computational cost. Extensive experiments on PASCAL Context, PASCAL VOC, ADE20K validate the effectiveness of the proposed EfficientFCN.

cs.CV↗

arXiv2020

Learning to Predict Context-adaptive Convolution for Semantic Segmentation

Long-range contextual information is essential for achieving high-performance semantic segmentation. Previous feature re-weighting methods demonstrate that using global context for re-weighting feature channels can effectively improve the accuracy of semantic segmentation. However, the globally-sharing feature re-weighting vector might not be optimal for regions of different classes in the input image. In this paper, we propose a Context-adaptive Convolution Network (CaC-Net) to predict a spatially-varying feature weighting vector for each spatial location of the semantic feature maps. In CaC-Net, a set of context-adaptive convolution kernels are predicted from the global contextual information in a parameter-efficient manner. When used for convolution with the semantic feature maps, the predicted convolutional kernels can generate the spatially-varying feature weighting factors capturing both global and local contextual information. Comprehensive experimental results show that our CaC-Net achieves superior segmentation performance on three public datasets, PASCAL Context, PASCAL VOC 2012 and ADE20K.

cs.CV↗

arXiv2020

Tensor Low-Rank Reconstruction for Semantic Segmentation

Context information plays an indispensable role in the success of semantic segmentation. Recently, non-local self-attention based methods are proved to be effective for context information collection. Since the desired context consists of spatial-wise and channel-wise attentions, 3D representation is an appropriate formulation. However, these non-local methods describe 3D context information based on a 2D similarity matrix, where space compression may lead to channel-wise attention missing. An alternative is to model the contextual information directly without compression. However, this effort confronts a fundamental difficulty, namely the high-rank property of context information. In this paper, we propose a new approach to model the 3D context representations, which not only avoids the space compression but also tackles the high-rank difficulty. Here, inspired by tensor canonical-polyadic decomposition theory (i.e, a high-rank tensor can be expressed as a combination of rank-1 tensors.), we design a low-rank-to-high-rank context reconstruction framework (i.e, RecoNet). Specifically, we first introduce the tensor generation module (TGM), which generates a number of rank-1 tensors to capture fragments of context feature. Then we use these rank-1 tensors to recover the high-rank context features through our proposed tensor reconstruction module (TRM). Extensive experiments show that our method achieves state-of-the-art on various public datasets. Additionally, our proposed method has more than 100 times less computational cost compared with conventional non-local-based methods.

cs.CV↗

arXiv2018

Prostate Segmentation using 2D Bridged U-net

In this paper, we focus on three problems in deep learning based medical image segmentation. Firstly, U-net, as a popular model for medical image segmentation, is difficult to train when convolutional layers increase even though a deeper network usually has a better generalization ability because of more learnable parameters. Secondly, the exponential ReLU (ELU), as an alternative of ReLU, is not much different from ReLU when the network of interest gets deep. Thirdly, the Dice loss, as one of the pervasive loss functions for medical image segmentation, is not effective when the prediction is close to ground truth and will cause oscillation during training. To address the aforementioned three problems, we propose and validate a deeper network that can fit medical image datasets that are usually small in the sample size. Meanwhile, we propose a new loss function to accelerate the learning process and a combination of different activation functions to improve the network performance. Our experimental results suggest that our network is comparable or superior to state-of-the-art methods.

cs.CV↗