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Junwen Guo

Publications and source records attributed to Junwen Guo.

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Rethinking Cross-Dose PET Denoising: Mitigating Averaging Effects via Residual Noise Learning

Cross-dose denoising for low-dose positron emission tomography (LDPET) has been proposed to address the limited generalization of models trained at a single noise level. However, neural networks trained on a specific dose level often fail to generalize to other dose conditions due to variations in noise magnitude and statistical properties. Conventional "one-size-for-all" models attempt to mitigate this variability but tend to learn averaged representations across noise levels, resulting in degraded performance. In this work, we analyze this limitation and show that standard training formulations implicitly optimize an expectation over heterogeneous noise distributions, causing the network to learn an averaged denoising mapping that cannot accurately model dose-specific noise characteristics. We propose a unified residual noise learning framework that estimates noise directly from low-dose PET images rather than predicting full-dose images. Experiments on large-scale multi-dose PET datasets from two medical centers demonstrate that the proposed method outperforms the "one-size-for-all" model, individual dose-specific U-Net models, and dose-conditioned approaches, achieving improved denoising performance. These results indicate that residual noise learning effectively mitigates the averaging effect and enhances generalization for cross-dose PET denoising.

cs.CV

Progressive Masked Refinement Self-supervised Learning for Low-Dose CT Denoising

Self-supervised learning has been increasingly investigated for low-dose computed tomography (LDCT) image denoising, as it alleviates the dependence on paired normal-dose CT (NDCT) data, which are often difficult to obtain. However, many existing self-supervised blind-spot denoising methods may under-utilize pixel-wise supervisory information loss due to evaluating the training loss only at masked locations. To mitigate this issue, we propose a novel Progressive Masked Refinement Learning framework that progressively refines denoising results while preserving and exploiting available LDCT information. Specifically, we explicitly inject a combination of controlled Gaussian and Poisson noise during training to regularize the denoising process and mitigate trivial identity mapping. Furthermore, we introduce a step-wise mask denoising mechanism that gradually reduces the discrepancy between synthetic corruption and the noise characteristics of LDCT images, enabling more fine-grained learning for denoising. Extensive experiments on the Mayo LDCT dataset demonstrate that the proposed method outperforms existing self-supervised approaches and achieves performance comparable to, or better than, several representative supervised denoising methods.

cs.CV

Hybrid Swin Attention Networks for Simultaneously Low-Dose PET and CT Denoising

Low-dose computed tomography (LDCT) and positron emission tomography (PET) have emerged as safer alternatives to conventional imaging modalities by significantly reducing radiation exposure. However, current approaches often face a trade$-$off between training stability and computational efficiency. In this study, we propose a novel Hybrid Swin Attention Network (HSANet), which incorporates Efficient Global Attention (EGA) modules and a hybrid upsampling module to address these limitations. The EGA modules enhance both spatial and channel-wise interaction, improving the network's capacity to capture relevant features, while the hybrid upsampling module mitigates the risk of overfitting to noise. We validate the proposed approach using a publicly available LDCT/PET dataset. Experimental results demonstrate that HSANet achieves superior denoising performance compared to state of the art methods, while maintaining a lightweight model size suitable for deployment on GPUs with standard memory configurations. Thus, our approach demonstrates significant potential for practical, real-world clinical applications.

cs.CV

Graph Context Transformation Learning for Progressive Correspondence Pruning

Most of existing correspondence pruning methods only concentrate on gathering the context information as much as possible while neglecting effective ways to utilize such information. In order to tackle this dilemma, in this paper we propose Graph Context Transformation Network (GCT-Net) enhancing context information to conduct consensus guidance for progressive correspondence pruning. Specifically, we design the Graph Context Enhance Transformer which first generates the graph network and then transforms it into multi-branch graph contexts. Moreover, it employs self-attention and cross-attention to magnify characteristics of each graph context for emphasizing the unique as well as shared essential information. To further apply the recalibrated graph contexts to the global domain, we propose the Graph Context Guidance Transformer. This module adopts a confident-based sampling strategy to temporarily screen high-confidence vertices for guiding accurate classification by searching global consensus between screened vertices and remaining ones. The extensive experimental results on outlier removal and relative pose estimation clearly demonstrate the superior performance of GCT-Net compared to state-of-the-art methods across outdoor and indoor datasets. The source code will be available at: https://github.com/guobaoxiao/GCT-Net/.

cs.CV