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Justin J. Slater

Publications and source records attributed to Justin J. Slater.

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Sequential Importance Sampling for Thinned Count Autoregressions via Latent Gaussian Transformations

Thinned count autoregressions are popular for modelling infectious disease surveillance data due to their flexibility and interpretability. However, such a model is challenging to fit since it involves high-dimensional and serially correlated integer-valued unknowns. One solution is to consider an analogous continuous-valued surrogate model whose values are post-hoc mapped to integers. This procedure produces biased estimates as inference is performed using samples from such a surrogate model and not the thinned count autoregression itself. In this work, we propose a sequential importance sampling procedure to correct this misspecified model. We demonstrate its validity in a simulation study and its applicability for epidemic curve reconstruction using rotavirus data from Germany and meningococcus data from France.

stat.ME

Modelling Under-Reported Data: Pitfalls of Naïve Approaches and a New Statistical Framework for Epidemic Curve Reconstruction

Count-valued autoregressions are widely used to analyse time-series of reported infectious-disease cases because of their close connection with discrete-time transmission models. However, when such models are applied directly to under-reported case counts, their mechanistic interpretation can break down. We establish new theoretical results quantifying the consequences of ignoring under-reporting in these models. To address this issue, reported cases are often modelled as a binomially thinned version of an underlying count process, but such models are difficult to fit because the unobserved true counts are serially correlated and integer-valued. We develop a new statistical framework for under-reported infectious-disease data that uses a normal-normal approximation to a broad class of thinned count autoregressions and then accurately maps this continuous process back to the integers. Through simulations and applications to rotavirus incidence in a German state and Covid-19 incidence in English conurbations, we demonstrate that our approach both retains the mechanistic appeal of thinned autoregressions and substantially simplifies inference.

stat.AP