arXiv subjects

Jutika Borah

Publications and source records attributed to Jutika Borah.

4 recordsLinked to original sources

arXiv2026

Interpretable Deep Learning Framework for Improved Disease Classification in Medical Imaging

Deep learning models have gained increasing adoption in medical image analysis. However, these models often produce overconfident predictions, which can compromise clinical accuracy and reliability. Bridging the gap between high-performance and awareness of uncertainty remains a crucial challenge in biomedical imaging applications. This study focuses on developing a unified deep learning framework for enhancing feature integration, interpretability, and reliability in prediction. We introduced a cross-guided channel spatial attention architecture that fuses feature representations extracted from EfficientNetB4 and ResNet34. Bidirectional attention approach enables the exchange of information across networks with differing receptive fields, enhancing discriminative and contextual feature learning. For quantitative predictive uncertainty assessment, Monte Carlo (MC)-Dropout is integrated with conformal prediction. This provides statistically valid prediction sets with entropy-based uncertainty visualization. The framework is evaluated on four medical imaging benchmark datasets: chest X-rays of COVID-19, Tuberculosis, Pneumonia, and retinal Optical Coherence Tomography (OCT) images. The proposed framework achieved strong classification performance with an AUC of 99.75% for COVID-19, 100% for Tuberculosis, 99.3% for Pneumonia chest X-rays, and 98.69% for retinal OCT images. Uncertainty-aware inference yields calibrated prediction sets with interpretable examples of uncertainty, showing transparency. The results demonstrate that bidirectional cross-attention with uncertainty quantification can improve performance and transparency in medical image classification.

eess.IV↗

arXiv2026

FALCON: Few-Shot Adversarial Learning for Cross-Domain Medical Image Segmentation

Precise delineation of anatomical and pathological structures within 3D medical volumes is crucial for accurate diagnosis, effective surgical planning, and longitudinal disease monitoring. Despite advancements in AI, clinically viable segmentation is often hindered by the scarcity of 3D annotations, patient-specific variability, data privacy concerns, and substantial computational overhead. In this work, we propose FALCON, a cross-domain few-shot segmentation framework that achieves high-precision 3D volume segmentation by processing data as 2D slices. The framework is first meta-trained on natural images to learn-to-learn generalizable segmentation priors, then transferred to the medical domain via adversarial fine-tuning and boundary-aware learning. Task-aware inference, conditioned on support cues, allows FALCON to adapt dynamically to patient-specific anatomical variations across slices. Experiments on four benchmarks demonstrate that FALCON consistently achieves the lowest Hausdorff Distance scores, indicating superior boundary accuracy while maintaining a Dice Similarity Coefficient comparable to the state-of-the-art models. Notably, these results are achieved with significantly less labeled data, no data augmentation, and substantially lower computational overhead.

cs.CV↗

arXiv2024

Disease Classification and Impact of Pretrained Deep Convolution Neural Networks on Diverse Medical Imaging Datasets across Imaging Modalities

Imaging techniques such as Chest X-rays, whole slide images, and optical coherence tomography serve as the initial screening and detection for a wide variety of medical pulmonary and ophthalmic conditions respectively. This paper investigates the intricacies of using pretrained deep convolutional neural networks with transfer learning across diverse medical imaging datasets with varying modalities for binary and multiclass classification. We conducted a comprehensive performance analysis with ten network architectures and model families each with pretraining and random initialization. Our finding showed that the use of pretrained models as fixed feature extractors yields poor performance irrespective of the datasets. Contrary, histopathology microscopy whole slide images have better performance. It is also found that deeper and more complex architectures did not necessarily result in the best performance. This observation implies that the improvements in ImageNet are not parallel to the medical imaging tasks. Within a medical domain, the performance of the network architectures varies within model families with shifts in datasets. This indicates that the performance of models within a specific modality may not be conclusive for another modality within the same domain. This study provides a deeper understanding of the applications of deep learning techniques in medical imaging and highlights the impact of pretrained networks across different medical imaging datasets under five different experimental settings.

eess.IV↗

arXiv2024

Predictive uncertainty estimation in deep learning for lung carcinoma classification in digital pathology under real dataset shifts

Deep learning has shown tremendous progress in a wide range of digital pathology and medical image classification tasks. Its integration into safe clinical decision-making support requires robust and reliable models. However, real-world data comes with diversities that often lie outside the intended source distribution. Moreover, when test samples are dramatically different, clinical decision-making is greatly affected. Quantifying predictive uncertainty in models is crucial for well-calibrated predictions and determining when (or not) to trust a model. Unfortunately, many works have overlooked the importance of predictive uncertainty estimation. This paper evaluates whether predictive uncertainty estimation adds robustness to deep learning-based diagnostic decision-making systems. We investigate the effect of various carcinoma distribution shift scenarios on predictive performance and calibration. We first systematically investigate three popular methods for improving predictive uncertainty: Monte Carlo dropout, deep ensemble, and few-shot learning on lung adenocarcinoma classification as a primary disease in whole slide images. Secondly, we compare the effectiveness of the methods in terms of performance and calibration under clinically relevant distribution shifts such as in-distribution shifts comprising primary disease sub-types and other characterization analysis data; out-of-distribution shifts comprising well-differentiated cases, different organ origin, and imaging modality shifts. While studies on uncertainty estimation exist, to our best knowledge, no rigorous large-scale benchmark compares predictive uncertainty estimation including these dataset shifts for lung carcinoma classification.

eess.IV↗