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Kamar Hibatallah Baghdadi

Publications and source records attributed to Kamar Hibatallah Baghdadi.

2 recordsLinked to original sources

Hierarchical Reinforcement Learning for Neural Network Compression (HiReLC): Pruning and Quantization

We present HiReLC, a hierarchical ensemble-reinforcement learning framework for automated joint quantization and structured pruning of deep neural networks. The framework decomposes the compression search across two levels of abstraction: low-level agents (LLAs) operate independently per block, selecting per-kernel configurations over a multi-discrete action space spanning bitwidth, pruning keep-ratio, quantization type, and granularity, while high-level agents (HLAs) coordinate global budget allocation via ensemble voting guided by Fisher Information-based sensitivity estimates. To mitigate the computational cost of policy evaluation, an iterative active learning loop interleaves surrogate-guided RL optimization with post-compression fine-tuning, using a lightweight MLP surrogate to amortize expensive evaluations and a logit-MSE proxy during cold-start. The surrogate is used for reward shaping rather than as a replacement for final post-compression evaluation. The controller is architecture-agnostic by design, with a modular layer abstraction decoupling the RL environment from the underlying network topology. Experiments across Vision Transformer and CNN benchmarks demonstrate effective parameter-storage compression ratios of 5.99 - 6.72$\times$ with a 3.83 % gain in one setting and 0.55 - 5.62 % accuracy drops elsewhere, supporting hierarchical policy decomposition and sensitivity-aware guidance as practical design choices for joint neural network compression.

cs.LG↗

VAMP-Net: An Interpretable Multi-Path Network of Genomic Permutation-Invariant Set Attention and Quality-Aware 1D-CNN for MTB Drug Resistance

Genomic prediction of drug resistance in Mycobacterium tuberculosis is often hindered by complex epistatic interactions and variable sequencing quality. We present the Interpretable Variant-Aware Multi-Path Network (VAMP-Net), a novel architecture addressing these challenges through a dual-pathway approach. Path-1 utilizes a Set Attention Transformer to model permutation-invariant variant sets and capture epistatic dependencies, while Path-2 employs a 1D-CNN to analyze VCF quality metrics for adaptive confidence scoring. Evaluated on four critical anti-TB drugs, VAMP-Net significantly outperforms baseline CNN and MLP models, achieving accuracies > 95% and AUCs around 0.97 for Rifampicin and Rifabutin. Feature attribution analysis via Integrated Gradients successfully recovered canonical targets (rpoB, embB, katG) and discovered high-impact novel loci. Functional enrichment confirmed these novel variants constitute non-random metabolic modules (p=0.00239) centered on cell-wall remodeling. Furthermore, systematic ablation of the Quality-Aware pathway demonstrates that the model performs a learned "integrated audit," prioritizing the Fraction of Supporting Reads and relative confidence over raw depth to mitigate technical noise. This dual-layer interpretability, bridging genomic pathogenicity with technical reliability, establishes a new paradigm for robust, auditable, and clinically actionable resistance prediction, positioning VAMP-Net as an important tool for both diagnostic classification and mechanistic discovery in clinical genomics.

cs.LG↗