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Kani Chen

Publications and source records attributed to Kani Chen.

35 records · Page 2Linked to original sources

Efficient semi-supervised inference for logistic regression under case-control studies

Semi-supervised learning has received increasingly attention in statistics and machine learning. In semi-supervised learning settings, a labeled data set with both outcomes and covariates and an unlabeled data set with covariates only are collected. We consider an inference problem in semi-supervised settings where the outcome in the labeled data is binary and the labeled data is collected by case-control sampling. Case-control sampling is an effective sampling scheme for alleviating imbalance structure in binary data. Under the logistic model assumption, case-control data can still provide consistent estimator for the slope parameter of the regression model. However, the intercept parameter is not identifiable. Consequently, the marginal case proportion cannot be estimated from case-control data. We find out that with the availability of the unlabeled data, the intercept parameter can be identified in semi-supervised learning setting. We construct the likelihood function of the observed labeled and unlabeled data and obtain the maximum likelihood estimator via an iterative algorithm. The proposed estimator is shown to be consistent, asymptotically normal, and semiparametrically efficient. Extensive simulation studies are conducted to show the finite sample performance of the proposed method. The results imply that the unlabeled data not only helps to identify the intercept but also improves the estimation efficiency of the slope parameter. Meanwhile, the marginal case proportion can be estimated accurately by the proposed method.

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Test-Time Compensated Representation Learning for Extreme Traffic Forecasting

Traffic forecasting is a challenging task due to the complex spatio-temporal correlations among traffic series. In this paper, we identify an underexplored problem in multivariate traffic series prediction: extreme events. Road congestion and rush hours can result in low correlation in vehicle speeds at various intersections during adjacent time periods. Existing methods generally predict future series based on recent observations and entirely discard training data during the testing phase, rendering them unreliable for forecasting highly nonlinear multivariate time series. To tackle this issue, we propose a test-time compensated representation learning framework comprising a spatio-temporal decomposed data bank and a multi-head spatial transformer model (CompFormer). The former component explicitly separates all training data along the temporal dimension according to periodicity characteristics, while the latter component establishes a connection between recent observations and historical series in the data bank through a spatial attention matrix. This enables the CompFormer to transfer robust features to overcome anomalous events while using fewer computational resources. Our modules can be flexibly integrated with existing forecasting methods through end-to-end training, and we demonstrate their effectiveness on the METR-LA and PEMS-BAY benchmarks. Extensive experimental results show that our method is particularly important in extreme events, and can achieve significant improvements over six strong baselines, with an overall improvement of up to 28.2%.

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Asymptotic Statistical Analysis of $f$-divergence GAN

Generative Adversarial Networks (GANs) have achieved great success in data generation. However, its statistical properties are not fully understood. In this paper, we consider the statistical behavior of the general $f$-divergence formulation of GAN, which includes the Kullback--Leibler divergence that is closely related to the maximum likelihood principle. We show that for parametric generative models that are correctly specified, all $f$-divergence GANs with the same discriminator classes are asymptotically equivalent under suitable regularity conditions. Moreover, with an appropriately chosen local discriminator, they become equivalent to the maximum likelihood estimate asymptotically. For generative models that are misspecified, GANs with different $f$-divergences {converge to different estimators}, and thus cannot be directly compared. However, it is shown that for some commonly used $f$-divergences, the original $f$-GAN is not optimal in that one can achieve a smaller asymptotic variance when the discriminator training in the original $f$-GAN formulation is replaced by logistic regression. The resulting estimation method is referred to as Adversarial Gradient Estimation (AGE). Empirical studies are provided to support the theory and to demonstrate the advantage of AGE over the original $f$-GANs under model misspecification.

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Time Series Generation with Masked Autoencoder

This paper shows that masked autoencoder with extrapolator (ExtraMAE) is a scalable self-supervised model for time series generation. ExtraMAE randomly masks some patches of the original time series and learns temporal dynamics by recovering the masked patches. Our approach has two core designs. First, ExtraMAE is self-supervised. Supervision allows ExtraMAE to effectively and efficiently capture the temporal dynamics of the original time series. Second, ExtraMAE proposes an extrapolator to disentangle two jobs of the decoder: recovering latent representations and mapping them back into the feature space. These unique designs enable ExtraMAE to consistently and significantly outperform state-of-the-art (SoTA) benchmarks in time series generation. The lightweight architecture also makes ExtraMAE fast and scalable. ExtraMAE shows outstanding behavior in various downstream tasks such as time series classification, prediction, and imputation. As a self-supervised generative model, ExtraMAE allows explicit management of the synthetic data. We hope this paper will usher in a new era of time series generation with self-supervised models.

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A General Pairwise Comparison Model for Extremely Sparse Networks

Statistical inference using pairwise comparison data is an effective approach to analyzing large-scale sparse networks. In this paper, we propose a general framework to model the mutual interactions in a network, which enjoys ample flexibility in terms of model parametrization. Under this setup, we show that the maximum likelihood estimator for the latent score vector of the subjects is uniformly consistent under a near-minimal condition on network sparsity. This condition is sharp in terms of the leading order asymptotics describing the sparsity. Our analysis utilizes a novel chaining technique and illustrates an important connection between graph topology and model consistency. Our results guarantee that the maximum likelihood estimator is justified for estimation in large-scale pairwise comparison networks where data are asymptotically deficient. Simulation studies are provided in support of our theoretical findings.

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IDEA: Interpretable Dynamic Ensemble Architecture for Time Series Prediction

We enhance the accuracy and generalization of univariate time series point prediction by an explainable ensemble on the fly. We propose an Interpretable Dynamic Ensemble Architecture (IDEA), in which interpretable base learners give predictions independently with sparse communication as a group. The model is composed of several sequentially stacked groups connected by group backcast residuals and recurrent input competition. Ensemble driven by end-to-end training both horizontally and vertically brings state-of-the-art (SOTA) performances. Forecast accuracy improves by 2.6% over the best statistical benchmark on the TOURISM dataset and 2% over the best deep learning benchmark on the M4 dataset. The architecture enjoys several advantages, being applicable to time series from various domains, explainable to users with specialized modular structure and robust to changes in task distribution.

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Combining case-control studies for identifiability and efficiency improvement in logistic regression

Can two separate case-control studies, one about Hepatitis disease and the other about Fibrosis, for example, be combined together? It would be hugely beneficial if two or more separately conducted case-control studies, even for entirely irrelevant purposes, can be merged together with a unified analysis that produces better statistical properties, e.g., more accurate estimation of parameters. In this paper, we show that, when using the popular logistic regression model, the combined/integrative analysis produces a more accurate estimation of the slope parameters than the single case-control study. It is known that, in a single logistic case-control study, the intercept is not identifiable, contrary to prospective studies. In combined case-control studies, however, the intercepts are proved to be identifiable under mild conditions. The resulting maximum likelihood estimates of the intercepts and slopes are proved to be consistent and asymptotically normal, with asymptotic variances achieving the semiparametric efficiency lower bound.

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Broken Adaptive Ridge Regression for Right-Censored Survival Data

Broken adaptive ridge (BAR) is a computationally scalable surrogate to $L_0$-penalized regression, which involves iteratively performing reweighted $L_2$ penalized regressions and enjoys some appealing properties of both $L_0$ and $L_2$ penalized regressions while avoiding some of their limitations. In this paper, we extend the BAR method to the semi-parametric accelerated failure time (AFT) model for right-censored survival data. Specifically, we propose a censored BAR (CBAR) estimator by applying the BAR algorithm to the Leurgan's synthetic data and show that the resulting CBAR estimator is consistent for variable selection, possesses an oracle property for parameter estimation {and enjoys a grouping property for highly correlation covariates}. Both low and high dimensional covariates are considered. The effectiveness of our method is demonstrated and compared with some popular penalization methods using simulations. Real data illustrations are provided on a diffuse large-B-cell lymphoma data and a glioblastoma multiforme data.

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Surprise sampling: improving and extending the local case-control sampling

Fithian and Hastie (2014) proposed a new sampling scheme called local case-control (LCC) sampling that achieves stability and efficiency by utilizing a clever adjustment pertained to the logistic model. It is particularly useful for classification with large and imbalanced data. This paper proposes a more general sampling scheme based on a working principle that data points deserve higher sampling probability if they contain more information or appear "surprising" in the sense of, for example, a large error of pilot prediction or a large absolute score. Compared with the relevant existing sampling schemes, as reported in Fithian and Hastie (2014) and Ai, et al. (2018), the proposed one has several advantages. It adaptively gives out the optimal forms to a variety of objectives, including the LCC and Ai et al. (2018)'s sampling as special cases. Under same model specifications, the proposed estimator also performs no worse than those in the literature. The estimation procedure is valid even if the model is misspecified and/or the pilot estimator is inconsistent or dependent on full data. We present theoretical justifications of the claimed advantages and optimality of the estimation and the sampling design. Different from Ai, et al. (2018), our large sample theory are population-wise rather than data-wise. Moreover, the proposed approach can be applied to unsupervised learning studies, since it essentially only requires a specific loss function and no response-covariate structure of data is needed. Numerical studies are carried out and the evidence in support of the theory is shown.

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Bidirectional Generative Modeling Using Adversarial Gradient Estimation

This paper considers the general $f$-divergence formulation of bidirectional generative modeling, which includes VAE and BiGAN as special cases. We present a new optimization method for this formulation, where the gradient is computed using an adversarially learned discriminator. In our framework, we show that different divergences induce similar algorithms in terms of gradient evaluation, except with different scaling. Therefore this paper gives a general recipe for a class of principled $f$-divergence based generative modeling methods. Theoretical justifications and extensive empirical studies are provided to demonstrate the advantage of our approach over existing methods.

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Curiosity-Driven Recommendation Strategy for Adaptive Learning via Deep Reinforcement Learning

The design of recommendations strategies in the adaptive learning system focuses on utilizing currently available information to provide individual-specific learning instructions for learners. As a critical motivate for human behaviors, curiosity is essentially the drive to explore knowledge and seek information. In a psychologically inspired view, we aim to incorporate the element of curiosity for guiding learners to study spontaneously. In this paper, a curiosity-driven recommendation policy is proposed under the reinforcement learning framework, allowing for a both efficient and enjoyable personalized learning mode. Given intrinsic rewards from a well-designed predictive model, we apply the actor-critic method to approximate the policy directly through neural networks. Numeric analyses with a large continuous knowledge state space and concrete learning scenarios are used to further demonstrate the power of the proposed method.

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Nearly Semiparametric Efficient Estimation of Quantile Regression

As a competitive alternative to least squares regression, quantile regression is popular in analyzing heterogenous data. For quantile regression model specified for one single quantile level $τ$, major difficulties of semiparametric efficient estimation are the unavailability of a parametric efficient score and the conditional density estimation. In this paper, with the help of the least favorable submodel technique, we first derive the semiparametric efficient scores for linear quantile regression models that are assumed for a single quantile level, multiple quantile levels and all the quantile levels in $(0,1)$ respectively. Our main discovery is a one-step (nearly) semiparametric efficient estimation for the regression coefficients of the quantile regression models assumed for multiple quantile levels, which has several advantages: it could be regarded as an optimal way to pool information across multiple/other quantiles for efficiency gain; it is computationally feasible and easy to implement, as the initial estimator is easily available; due to the nature of quantile regression models under investigation, the conditional density estimation is straightforward by plugging in an initial estimator. The resulting estimator is proved to achieve the corresponding semiparametric efficiency lower bound under regularity conditions. Numerical studies including simulations and an example of birth weight of children confirms that the proposed estimator leads to higher efficiency compared with the Koenker-Bassett quantile regression estimator for all quantiles of interest.

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Estimation of Dynamic Mixed Double Factors Model in High Dimensional Panel Data

The purpose of this article is to develop the dimension reduction techniques in panel data analysis when the number of individuals and indicators is large. We use Principal Component Analysis (PCA) method to represent large number of indicators by minority common factors in the factor models. We propose the Dynamic Mixed Double Factor Model (DMDFM for short) to re ect cross section and time series correlation with interactive factor structure. DMDFM not only reduce the dimension of indicators but also consider the time series and cross section mixed effect. Different from other models, mixed factor model have two styles of common factors. The regressors factors re flect common trend and reduce the dimension, error components factors re ect difference and weak correlation of individuals. The results of Monte Carlo simulation show that Generalized Method of Moments (GMM) estimators have good unbiasedness and consistency. Simulation also shows that the DMDFM can improve prediction power of the models effectively.

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Regression Analysis with Response-biased Sampling

Response-biased sampling, in which samples are drawn from a popula- tion according to the values of the response variable, is common in biomedical, epidemiological, economic and social studies. In particular, the complete obser- vations in data with censoring, truncation or missing covariates can be regarded as response-biased sampling under certain conditions. This paper proposes to use transformation models, known as the generalized accelerated failure time model in econometrics, for regression analysis with response-biased sampling. With unknown error distribution, the transformation models are broad enough to cover linear re- gression models, the Cox's model and the proportional odds model as special cases. To the best of our knowledge, except for the case-control logistic regression, there is no report in the literature that a prospective estimation approach can work for biased sampling without any modification. We prove that the maximum rank corre- lation estimation is valid for response-biased sampling and establish its consistency and asymptotic normality. Unlike the inverse probability methods, the proposed method of estimation does not involve the sampling probabilities, which are often difficult to obtain in practice. Without the need of estimating the unknown trans- formation function or the error distribution, the proposed method is numerically easy to implement with the Nelder-Mead simplex algorithm, which does not require convexity or continuity. We propose an inference procedure using random weight- ing to avoid the complication of density estimation when using the plug-in rule for variance estimation. Numerical studies with supportive evidence are presented. Applications are illustrated with the Forbes Global 2000 data and the Stanford heart transplant data.

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Least Product Relative Error Estimation

A least product relative error criterion is proposed for multiplicative regression models. It is invariant under scale transformation of the outcome and covariates. In addition, the objective function is smooth and convex, resulting in a simple and uniquely defined estimator of the regression parameter. It is shown that the estimator is asymptotically normal and that the simple plugging-in variance estimation is valid. Simulation results confirm that the proposed method performs well. An application to body fat calculation is presented to illustrate the new method.

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Functional and Parametric Estimation in a Semi- and Nonparametric Model with Application to Mass-Spectrometry Data

Motivated by modeling and analysis of mass-spectrometry data, a semi- and nonparametric model is proposed that consists of a linear parametric component for individual location and scale and a nonparametric regression function for the common shape. A multi-step approach is developed that simultaneously estimates the parametric components and the nonparametric function. Under certain regularity conditions, it is shown that the resulting estimators is consistent and asymptotic normal for the parametric part and achieve the optimal rate of convergence for the nonparametric part when the bandwidth is suitably chosen. Simulation results are presented to demonstrate the effectiveness and finite-sample performance of the method. The method is also applied to a SELDI-TOF mass spectrometry data set from a study of liver cancer patients.

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Statistical estimation in the proportional hazards model with risk set sampling

Thomas' partial likelihood estimator of regression parameters is widely used in the analysis of nested case-control data with Cox's model. This paper proposes a new estimator of the regression parameters, which is consistent and asymptotically normal. Its asymptotic variance is smaller than that of Thomas' estimator away from the null. Unlike some other existing estimators, the proposed estimator does not rely on any more data than strictly necessary for Thomas' estimator and is easily computable from a closed form estimating equation with a unique solution. The variance estimation is obtained as minus the inverse of the derivative of the estimating function and therefore the inference is easily available. A numerical example is provided in support of the theory.

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