SearcharxivSearch

arXiv subjects

Kartik Chhajed

Publications and source records attributed to Kartik Chhajed.

3 recordsLinked to original sources

Cell size heterogeneity controls crystallization of the developing fruit fly wing

A fundamental question in biology is to understand how patterns and shapes emerge from the collective interplay of large numbers of cells. Cells forming two-dimensional epithelial tissues behave as active materials that undergo remodeling and spontaneous shape changes. Focusing on the fly wing as a model system, we find that the cellular packing in the wing epithelium transitions from a disordered packing to an ordered, crystalline packing. While previous studies propose a role of tissue shear flow in establishing the ordered cell packing in the fly wing, we reveal a role of cell size heterogeneity. Indeed, we find that even if tissue shear have been inhibited, cell packings in the fruit fly wing epithelium transition from disordered to an ordered packing. We propose that the transition is controlled by the cell size heterogeneity, which is quantified by the cell size polydispersity. To explore the role of cell size polydispersity in controlling cellular packings, we implement polydispersity in a vertex model of epithelial tissues. Through numerical simulations of this model, we show that there is a critical value of cell size polydispersity above which cellular packings are disordered and below which they form a crystalline packing. By analyzing experimental data, we find that cell size polydispersity decreases during fly wing development. The observed dynamics of tissue crystallisation is consistent with the slow ordering kinetics we observe in the vertex model. Therefore, although tissue shear does not control the transition, it significantly enhances the rate of tissue-scale ordering by facilitating alignment of locally ordered crystallites. Our results identify cell size heterogeneity as a control parameter, in both the vertex model and the fruit fly wing epithelium, controlling the transition between ordered and disordered cellular packings.

physics.bio-ph

Absorbing phase transitions with memory in critical scaling

Many driven systems alternate between bursts of activity and quiescence and can become trapped in an absorbing state, such as complete inactivity in reaction-diffusion processes or extinction in predator-prey dynamics. It is generally assumed that, conditioned on survival, their long-lived (quasi-stationary) behavior is unique and independent of the initial condition. We show this need not hold, even for memoryless Markov dynamics. When the configuration space fractures into multiple macroscopic communicating classes, where configurations can be reach from one another within a class but not across classes, the system retains a measurable memory of its preparation, which can directly affect the critical exponents near absorbing transitions. Using a minimal birth-death-diffusion model, we demonstrate that the quasi-stationary state is unique when birth processes are present, but becomes nonunique and initial-condition dependent when they are suppressed. This mechanism, arising from vanishing of inter-class escape-rate ratios in thermodynamic limit, challenges the conventional universality hypothesis and suggests possibility of history-dependent critical scaling in controlled lattice or colloidal systems with tunable particle-number.

cond-mat.stat-mech

From Ising model to Kitaev Chain -- An introduction to topological phase transitions

In this general article, we map the one-dimensional transverse field quantum Ising model of ferromagnetism to Kitaev's one-dimensional p-wave superconductor, which has its application in fault-tolerant topological quantum computing. Mapping Pauli's spin operators of transverse Ising chain to spinless fermionic creation and annihilation operators by Inverse Jordan-Wigner transformation leads to a Hamiltonian form closely related to Kitaev Chain, which exhibits topological phase transition where phases are characterized by different topological invariant that changes discontinuously at the transition point. Kitaev Chain supports two Majorana zero modes (MZMs) in the non-trivial topological phase, while none is in the trivial phase. The doubly degenerate ground state of the transverse Ising in ferromagnetic phase corresponds to non-local free fermion degree made from MZMs. The quasi-particle excitations of Ising chain, viz., domain wall formation in the ferromagnetic phase and spin-flip in paramagnetic phase maps to Bogoliubon excitations. The mapping suggests that a non-local order parameter can be defined for Kitaev Chain to work with the usual paradigm of Landau's theory.

cond-mat.mes-hall