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Kayvan Najarian

Publications and source records attributed to Kayvan Najarian.

At least 37 records · Page 2Linked to original sources

Multiple Abnormality Detection for Automatic Medical Image Diagnosis Using Bifurcated Convolutional Neural Network

Automating classification and segmentation process of abnormal regions in different body organs has a crucial role in most of medical imaging applications such as funduscopy, endoscopy, and dermoscopy. Detecting multiple abnormalities in each type of images is necessary for better and more accurate diagnosis procedure and medical decisions. In recent years portable medical imaging devices such as capsule endoscopy and digital dermatoscope have been introduced and made the diagnosis procedure easier and more efficient. However, these portable devices have constrained power resources and limited computational capability. To address this problem, we propose a bifurcated structure for convolutional neural networks performing both classification and segmentation of multiple abnormalities simultaneously. The proposed network is first trained by each abnormality separately. Then the network is trained using all abnormalities. In order to reduce the computational complexity, the network is redesigned to share some features which are common among all abnormalities. Later, these shared features are used in different settings (directions) to segment and classify the abnormal region of the image. Finally, results of the classification and segmentation directions are fused to obtain the classified segmentation map. Proposed framework is simulated using four frequent gastrointestinal abnormalities as well as three dermoscopic lesions and for evaluation of the proposed framework the results are compared with the corresponding ground truth map. Properties of the bifurcated network like low complexity and resource sharing make it suitable to be implemented as a part of portable medical imaging devices.

cs.CV↗

Segmentation of Bleeding Regions in Wireless Capsule Endoscopy for Detection of Informative Frames

Wireless capsule endoscopy (WCE) is an effective mean for diagnosis of gastrointestinal disorders. Detection of informative scenes in WCE video could reduce the length of transmitted videos and help the diagnosis procedure. In this paper, we investigate the problem of simplification of neural networks for automatic bleeding region detection inside capsule endoscopy device. Suitable color channels are selected as neural networks inputs, and image classification is conducted using a multi-layer perceptron (MLP) and a convolutional neural network (CNN) separately. Both CNN and MLP structures are simplified to reduce the number of computational operations. Performances of two simplified networks are evaluated on a WCE bleeding image dataset using the DICE score. Simulation results show that applying simplification methods on both MLP and CNN structures reduces the number of computational operations significantly with AUC greater than 0.97. Although CNN performs better in comparison with simplified MLP, the simplified MLP segments bleeding regions with a significantly smaller number of computational operations. Concerning the importance of having a simple structure or a more accurate model, each of the designed structures could be selected for inside capsule implementation.

cs.CV↗

Deep Learning in Pharmacogenomics: From Gene Regulation to Patient Stratification

This Perspective provides examples of current and future applications of deep learning in pharmacogenomics, including: (1) identification of novel regulatory variants located in noncoding domains and their function as applied to pharmacoepigenomics; (2) patient stratification from medical records; and (3) prediction of drugs, targets, and their interactions. Deep learning encapsulates a family of machine learning algorithms that over the last decade has transformed many important subfields of artificial intelligence (AI) and has demonstrated breakthrough performance improvements on a wide range of tasks in biomedicine. We anticipate that in the future deep learning will be widely used to predict personalized drug response and optimize medication selection and dosing, using knowledge extracted from large and complex molecular, epidemiological, clinical, and demographic datasets.

q-bio.QM↗

Liver segmentation in CT images using three dimensional to two dimensional fully convolutional network

The need for CT scan analysis is growing for pre-diagnosis and therapy of abdominal organs. Automatic organ segmentation of abdominal CT scan can help radiologists analyze the scans faster and segment organ images with fewer errors. However, existing methods are not efficient enough to perform the segmentation process for victims of accidents and emergencies situations. In this paper we propose an efficient liver segmentation with our 3D to 2D fully connected network (3D-2D-FCN). The segmented mask is enhanced by means of conditional random field on the organ's border. Consequently, we segment a target liver in less than a minute with Dice score of 93.52.

cs.CV↗

Adaptive specular reflection detection and inpainting in colonoscopy video frames

Colonoscopy video frames might be contaminated by bright spots with unsaturated values known as specular reflection. Detection and removal of such reflections could enhance the quality of colonoscopy images and facilitate diagnosis procedure. In this paper we propose a novel two-phase method for this purpose, consisting of detection and removal phases. In the detection phase, we employ both HSV and RGB color space information for segmentation of specular reflections. We first train a non-linear SVM for selecting a color space based on image statistical features extracted from each channel of the color spaces. Then, a cost function for detection of specular reflections is introduced. In the removal phase, we propose a two-step inpainting method which consists of appropriate replacement patch selection and removal of the blockiness effects. The proposed method is evaluated by testing on an available colonoscopy image database where accuracy and Dice score of 99.68% and 71.79% are achieved respectively.

cs.CV↗

Left ventricle segmentation By modelling uncertainty in prediction of deep convolutional neural networks and adaptive thresholding inference

Deep neural networks have shown great achievements in solving complex problems. However, there are fundamental problems that limit their real world applications. Lack of measurable criteria for estimating uncertainty in the network outputs is one of these problems. In this paper, we address this limitation by introducing deformation to the network input and measuring the level of stability in the network's output. We calculate simple random transformations to estimate the prediction uncertainty of deep convolutional neural networks. For a real use-case, we apply this method to left ventricle segmentation in MRI cardiac images. We also propose an adaptive thresholding method to consider the deep neural network uncertainty. Experimental results demonstrate state-of-the-art performance and highlight the capabilities of simple methods in conjunction with deep neural networks.

cs.CV↗

Lossless Compression of Angiogram Foreground with Visual Quality Preservation of Background

By increasing the volume of telemedicine information, the need for medical image compression has become more important. In angiographic images, a small ratio of the entire image usually belongs to the vasculature that provides crucial information for diagnosis. Other parts of the image are diagnostically less important and can be compressed with higher compression ratio. However, the quality of those parts affect the visual perception of the image as well. Existing methods compress foreground and background of angiographic images using different techniques. In this paper we first utilize convolutional neural network to segment vessels and then represent a hierarchical block processing algorithm capable of both eliminating the background redundancies and preserving the overall visual quality of angiograms.

cs.CV↗

Left Ventricle Segmentation in Cardiac MR Images Using Fully Convolutional Network

Medical image analysis, especially segmenting a specific organ, has an important role in developing clinical decision support systems. In cardiac magnetic resonance (MR) imaging, segmenting the left and right ventricles helps physicians diagnose different heart abnormalities. There are challenges for this task, including the intensity and shape similarity between left ventricle and other organs, inaccurate boundaries and presence of noise in most of the images. In this paper we propose an automated method for segmenting the left ventricle in cardiac MR images. We first automatically extract the region of interest, and then employ it as an input of a fully convolutional network. We train the network accurately despite the small number of left ventricle pixels in comparison with the whole image. Thresholding on the output map of the fully convolutional network and selection of regions based on their roundness are performed in our proposed post-processing phase. The Dice score of our method reaches 87.24% by applying this algorithm on the York dataset of heart images.

cs.CV↗

Lossless Image Compression Algorithm for Wireless Capsule Endoscopy by Content-Based Classification of Image Blocks

Recent advances in capsule endoscopy systems have introduced new methods and capabilities. The capsule endoscopy system, by observing the entire digestive tract, has significantly improved diagnosing gastrointestinal disorders and diseases. The system has challenges such as the need to enhance the quality of the transmitted images, low frame rates of transmission, and battery lifetime that need to be addressed. One of the important parts of a capsule endoscopy system is the image compression unit. Better compression of images increases the frame rate and hence improves the diagnosis process. In this paper a high precision compression algorithm with high compression ratio is proposed. In this algorithm we use the similarity between frames to compress the data more efficiently.

cs.CV↗

Reversible Image Watermarking for Health Informatics Systems Using Distortion Compensation in Wavelet Domain

Reversible image watermarking guaranties restoration of both original cover and watermark logo from the watermarked image. Capacity and distortion of the image under reversible watermarking are two important parameters. In this study a reversible watermarking is investigated with focusing on increasing the embedding capacity and reducing the distortion in medical images. Integer wavelet transform is used for embedding where in each iteration, one watermark bit is embedded in one transform coefficient. We devise a novel approach that when a coefficient is modified in an iteration, the produced distortion is compensated in the next iteration. This distortion compensation method would result in low distortion rate. The proposed method is tested on four types of medical images including MRI of brain, cardiac MRI, MRI of breast, and intestinal polyp images. Using a one-level wavelet transform, maximum capacity of 1.5 BPP is obtained. Experimental results demonstrate that the proposed method is superior to the state-of-the-art works in terms of capacity and distortion.

cs.CV↗

Segmentation of Bleeding Regions in Wireless Capsule Endoscopy Images an Approach for inside Capsule Video Summarization

Wireless capsule endoscopy (WCE) is an effective means of diagnosis of gastrointestinal disorders. Detection of informative scenes by WCE could reduce the length of transmitted videos and can help with the diagnosis. In this paper we propose a simple and efficient method for segmentation of the bleeding regions in WCE captured images. Suitable color channels are selected and classified by a multi-layer perceptron (MLP) structure. The MLP structure is quantized such that the implementation does not require multiplications. The proposed method is tested by simulation on WCE bleeding image dataset. The proposed structure is designed considering hardware resource constrains that exist in WCE systems.

cs.CV↗

Classification of Informative Frames in Colonoscopy Videos Using Convolutional Neural Networks with Binarized Weights

Colorectal cancer is one of the common cancers in the United States. Polyp is one of the main causes of the colonic cancer and early detection of polyps will increase chance of cancer treatments. In this paper, we propose a novel classification of informative frames based on a convolutional neural network with binarized weights. The proposed CNN is trained with colonoscopy frames along with the labels of the frames as input data. We also used binarized weights and kernels to reduce the size of CNN and make it suitable for implementation in medical hardware. We evaluate our proposed method using Asu Mayo Test clinic database, which contains colonoscopy videos of different patients. Our proposed method reaches a dice score of 71.20% and accuracy of more than 90% using the mentioned dataset.

eess.IV↗

Polyp Segmentation in Colonoscopy Images Using Fully Convolutional Network

Colorectal cancer is a one of the highest causes of cancer-related death, especially in men. Polyps are one of the main causes of colorectal cancer and early diagnosis of polyps by colonoscopy could result in successful treatment. Diagnosis of polyps in colonoscopy videos is a challenging task due to variations in the size and shape of polyps. In this paper we proposed a polyp segmentation method based on convolutional neural network. Performance of the method is enhanced by two strategies. First, we perform a novel image patch selection method in the training phase of the network. Second, in the test phase, we perform an effective post processing on the probability map that is produced by the network. Evaluation of the proposed method using the CVC-ColonDB database shows that our proposed method achieves more accurate results in comparison with previous colonoscopy video-segmentation methods.

eess.IV↗

Adaptive Real-Time Removal of Impulse Noise in Medical Images

Noise is an important factor that degrades the quality of medical images. Impulse noise is a common noise, which is caused by malfunctioning of sensor elements or errors in the transmission of images. In medical images due to presence of white foreground and black background, many pixels have intensities similar to impulse noise and distinction between noisy and regular pixels is difficult. In software techniques, the accuracy of the noise removal is more important than the algorithm's complexity. But for hardware implementation having a low complexity algorithm with an acceptable accuracy is essential. In this paper a low complexity de-noising method is proposed that removes the noise by local analysis of the image blocks. The proposed method distinguishes non-noisy pixels that have noise-like intensities. All steps are designed to have low hardware complexity. Simulation results show that for different magnetic resonance images, the proposed method removes impulse noise with an acceptable accuracy.

cs.CV↗

Vessel Segmentation and Catheter Detection in X-Ray Angiograms Using Superpixels

Coronary artery disease (CAD) is the leading causes of death around the world. One of the most common imaging methods for diagnosing this disease is X-ray angiography. Diagnosing using these images is usually challenging due to non-uniform illumination, low contrast, presence of other body tissues, presence of catheter etc. These challenges make the diagnoses task of cardiologists tougher and more prone to misdiagnosis. In this paper we propose a new automated framework for coronary arteries segmentation, catheter detection and center-line extraction in x-ray angiography images. Our proposed segmentation method is based on superpixels. In this method at first three different superpixel scales are exploited and a measure for vesselness probability of each superpixel is determined. A majority voting is used for obtaining an initial segmentation map from these three superpixel scales. This initial segmentation is refined by finding the orthogonal line on each ridge pixel of vessel region. In this framework we use our catheter detection and tracking method which detects the catheter by finding its ridge in the first frame and traces in other frames by fitting a second order polynomial on it. Also we use the image ridges for extracting the coronary arteries centerlines. We evaluated our method qualitatively and quantitatively on two different challenging datasets and compared it with one of the previous well-known coronary arteries segmentation methods. Our method could detect the catheter and reduced the false positive rate in addition to achieving better segmentation results. The evaluation results prove that our method performs better in a much shorter time.

cs.CV↗

Blind Stereo Image Quality Assessment Inspired by Brain Sensory-Motor Fusion

The use of 3D and stereo imaging is rapidly increasing. Compression, transmission, and processing could degrade the quality of stereo images. Quality assessment of such images is different than their 2D counterparts. Metrics that represent 3D perception by human visual system (HVS) are expected to assess stereoscopic quality more accurately. In this paper, inspired by brain sensory/motor fusion process, two stereo images are fused together. Then from every fused image two synthesized images are extracted. Effects of different distortions on statistical distributions of the synthesized images are shown. Based on the observed statistical changes, features are extracted from these synthesized images. These features can reveal type and severity of distortions. Then, a stacked neural network model is proposed, which learns the extracted features and accurately evaluates the quality of stereo images. This model is tested on 3D images of popular databases. Experimental results show the superiority of this method over state of the art stereo image quality assessment approaches

cs.CV↗

Real-Time Impulse Noise Removal from MR Images for Radiosurgery Applications

In the recent years image processing techniques are used as a tool to improve detection and diagnostic capabilities in the medical applications. Medical applications have been so much affected by these techniques which some of them are embedded in medical instruments such as MRI, CT and other medical devices. Among these techniques, medical image enhancement algorithms play an essential role in removal of the noise which can be produced by medical instruments and during image transfer. It has been proved that impulse noise is a major type of noise, which is produced during medical operations, such as MRI, CT, and angiography, by their image capturing devices. An embeddable hardware module which is able to denoise medical images before and during surgical operations could be very helpful. In this paper an accurate algorithm is proposed for real-time removal of impulse noise in medical images. All image blocks are divided into three categories of edge, smooth, and disordered areas. A different reconstruction method is applied to each category of blocks for the purpose of noise removal. The proposed method is tested on MR images. Simulation results show acceptable denoising accuracy for various levels of noise. Also an FPAG implementation of our denoising algorithm shows acceptable hardware resource utilization. Hence, the algorithm is suitable for embedding in medical hardware instruments such as radiosurgery devices.

cs.AR↗

Hand Gesture Recognition for Contactless Device Control in Operating Rooms

Hand gesture is one of the most important means of touchless communication between human and machines. There is a great interest for commanding electronic equipment in surgery rooms by hand gesture for reducing the time of surgery and the potential for infection. There are challenges in implementation of a hand gesture recognition system. It has to fulfill requirements such as high accuracy and fast response. In this paper we introduce a system of hand gesture recognition based on a deep learning approach. Deep learning is known as an accurate detection model, but its high complexity prevents it from being fabricated as an embedded system. To cope with this problem, we applied some changes in the structure of our work to achieve low complexity. As a result, the proposed method could be implemented on a naive embedded system. Our experiments show that the proposed system results in higher accuracy while having less complexity in comparison with the existing comparable methods.

cs.CV↗