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Ke Yan

Publications and source records attributed to Ke Yan.

121 records · Page 7Linked to original sources

Deep Learning for Image Denoising: A Survey

Since the proposal of big data analysis and Graphic Processing Unit (GPU), the deep learning technology has received a great deal of attention and has been widely applied in the field of imaging processing. In this paper, we have an aim to completely review and summarize the deep learning technologies for image denoising proposed in recent years. Morever, we systematically analyze the conventional machine learning methods for image denoising. Finally, we point out some research directions for the deep learning technologies in image denoising.

cs.CV↗

Passively Q-switching cylindrical vector beam fiber laser operating in high-order mode

We experimentally demonstrate a linear-cavity all-fiber passively Q-switching cylindrical vector beam (CVB) laser operating in high-order mode. This CVB fiber laser operates without any mode converter which always leads to high insertion loss, and it can realize high efficiency. In this fiber laser, the stable Q-switching pulse is achieved with a slope efficiency of 39%. By properly adjusting the polarization controllers, radially polarized and azimuthally polarized beams can be obtained. Our work proves the feasibility of achieving the stable Q-switching CVB pulse with high-order mode directly oscillating, and it may have an enormous potential for enhancing the efficiency.

physics.optics↗

3D Context Enhanced Region-based Convolutional Neural Network for End-to-End Lesion Detection

Detecting lesions from computed tomography (CT) scans is an important but difficult problem because non-lesions and true lesions can appear similar. 3D context is known to be helpful in this differentiation task. However, existing end-to-end detection frameworks of convolutional neural networks (CNNs) are mostly designed for 2D images. In this paper, we propose 3D context enhanced region-based CNN (3DCE) to incorporate 3D context information efficiently by aggregating feature maps of 2D images. 3DCE is easy to train and end-to-end in training and inference. A universal lesion detector is developed to detect all kinds of lesions in one algorithm using the DeepLesion dataset. Experimental results on this challenging task prove the effectiveness of 3DCE. We have released the code of 3DCE in https://github.com/rsummers11/CADLab/tree/master/lesion_detector_3DCE.

cs.CV↗

Deep Lesion Graphs in the Wild: Relationship Learning and Organization of Significant Radiology Image Findings in a Diverse Large-scale Lesion Database

Radiologists in their daily work routinely find and annotate significant abnormalities on a large number of radiology images. Such abnormalities, or lesions, have collected over years and stored in hospitals' picture archiving and communication systems. However, they are basically unsorted and lack semantic annotations like type and location. In this paper, we aim to organize and explore them by learning a deep feature representation for each lesion. A large-scale and comprehensive dataset, DeepLesion, is introduced for this task. DeepLesion contains bounding boxes and size measurements of over 32K lesions. To model their similarity relationship, we leverage multiple supervision information including types, self-supervised location coordinates and sizes. They require little manual annotation effort but describe useful attributes of the lesions. Then, a triplet network is utilized to learn lesion embeddings with a sequential sampling strategy to depict their hierarchical similarity structure. Experiments show promising qualitative and quantitative results on lesion retrieval, clustering, and classification. The learned embeddings can be further employed to build a lesion graph for various clinically useful applications. We propose algorithms for intra-patient lesion matching and missing annotation mining. Experimental results validate their effectiveness.

cs.CV↗

CT Image Enhancement Using Stacked Generative Adversarial Networks and Transfer Learning for Lesion Segmentation Improvement

Automated lesion segmentation from computed tomography (CT) is an important and challenging task in medical image analysis. While many advancements have been made, there is room for continued improvements. One hurdle is that CT images can exhibit high noise and low contrast, particularly in lower dosages. To address this, we focus on a preprocessing method for CT images that uses stacked generative adversarial networks (SGAN) approach. The first GAN reduces the noise in the CT image and the second GAN generates a higher resolution image with enhanced boundaries and high contrast. To make up for the absence of high quality CT images, we detail how to synthesize a large number of low- and high-quality natural images and use transfer learning with progressively larger amounts of CT images. We apply both the classic GrabCut method and the modern holistically nested network (HNN) to lesion segmentation, testing whether SGAN can yield improved lesion segmentation. Experimental results on the DeepLesion dataset demonstrate that the SGAN enhancements alone can push GrabCut performance over HNN trained on original images. We also demonstrate that HNN + SGAN performs best compared against four other enhancement methods, including when using only a single GAN.

cs.CV↗

Accurate Weakly-Supervised Deep Lesion Segmentation using Large-Scale Clinical Annotations: Slice-Propagated 3D Mask Generation from 2D RECIST

Volumetric lesion segmentation from computed tomography (CT) images is a powerful means to precisely assess multiple time-point lesion/tumor changes. However, because manual 3D segmentation is prohibitively time consuming, current practices rely on an imprecise surrogate called response evaluation criteria in solid tumors (RECIST). Despite their coarseness, RECIST markers are commonly found in current hospital picture and archiving systems (PACS), meaning they can provide a potentially powerful, yet extraordinarily challenging, source of weak supervision for full 3D segmentation. Toward this end, we introduce a convolutional neural network (CNN) based weakly supervised slice-propagated segmentation (WSSS) method to 1) generate the initial lesion segmentation on the axial RECIST-slice; 2) learn the data distribution on RECIST-slices; 3) extrapolate to segment the whole lesion slice by slice to finally obtain a volumetric segmentation. To validate the proposed method, we first test its performance on a fully annotated lymph node dataset, where WSSS performs comparably to its fully supervised counterparts. We then test on a comprehensive lesion dataset with 32,735 RECIST marks, where we report a mean Dice score of 92% on RECIST-marked slices and 76% on the entire 3D volumes.

cs.CV↗

Information Design in Crowdfunding under Thresholding Policies

Crowdfunding has emerged as a prominent way for entrepreneurs to secure funding without sophisticated intermediation. In crowdfunding, an entrepreneur often has to decide how to disclose the campaign status in order to collect as many contributions as possible. Such decisions are difficult to make primarily due to incomplete information. We propose information design as a tool to help the entrepreneur to improve revenue by influencing backers' beliefs. We introduce a heuristic algorithm to dynamically compute information-disclosure policies for the entrepreneur, followed by an empirical evaluation to demonstrate its competitiveness over the widely-adopted immediate-disclosure policy. Our results demonstrate that the immediate-disclosure policy is not optimal when backers follow thresholding policies despite its ease of implementation. With appropriate heuristics, an entrepreneur can benefit from dynamic information disclosure. Our work sheds light on information design in a dynamic setting where agents make decisions using thresholding policies.

cs.AI↗

Unsupervised Body Part Regression via Spatially Self-ordering Convolutional Neural Networks

Automatic body part recognition for CT slices can benefit various medical image applications. Recent deep learning methods demonstrate promising performance, with the requirement of large amounts of labeled images for training. The intrinsic structural or superior-inferior slice ordering information in CT volumes is not fully exploited. In this paper, we propose a convolutional neural network (CNN) based Unsupervised Body part Regression (UBR) algorithm to address this problem. A novel unsupervised learning method and two inter-sample CNN loss functions are presented. Distinct from previous work, UBR builds a coordinate system for the human body and outputs a continuous score for each axial slice, representing the normalized position of the body part in the slice. The training process of UBR resembles a self-organization process: slice scores are learned from inter-slice relationships. The training samples are unlabeled CT volumes that are abundant, thus no extra annotation effort is needed. UBR is simple, fast, and accurate. Quantitative and qualitative experiments validate its effectiveness. In addition, we show two applications of UBR in network initialization and anomaly detection.

cs.CV↗

Accurate Weakly Supervised Deep Lesion Segmentation on CT Scans: Self-Paced 3D Mask Generation from RECIST

Volumetric lesion segmentation via medical imaging is a powerful means to precisely assess multiple time-point lesion/tumor changes. Because manual 3D segmentation is prohibitively time consuming and requires radiological experience, current practices rely on an imprecise surrogate called response evaluation criteria in solid tumors (RECIST). Despite their coarseness, RECIST marks are commonly found in current hospital picture and archiving systems (PACS), meaning they can provide a potentially powerful, yet extraordinarily challenging, source of weak supervision for full 3D segmentation. Toward this end, we introduce a convolutional neural network based weakly supervised self-paced segmentation (WSSS) method to 1) generate the initial lesion segmentation on the axial RECIST-slice; 2) learn the data distribution on RECIST-slices; 3) adapt to segment the whole volume slice by slice to finally obtain a volumetric segmentation. In addition, we explore how super-resolution images (2~5 times beyond the physical CT imaging), generated from a proposed stacked generative adversarial network, can aid the WSSS performance. We employ the DeepLesion dataset, a comprehensive CT-image lesion dataset of 32,735 PACS-bookmarked findings, which include lesions, tumors, and lymph nodes of varying sizes, categories, body regions and surrounding contexts. These are drawn from 10,594 studies of 4,459 patients. We also validate on a lymph-node dataset, where 3D ground truth masks are available for all images. For the DeepLesion dataset, we report mean Dice coefficients of 93% on RECIST-slices and 76% in 3D lesion volumes. We further validate using a subjective user study, where an experienced radiologist accepted our WSSS-generated lesion segmentation results with a high probability of 92.4%.

cs.CV↗

DeepLesion: Automated Deep Mining, Categorization and Detection of Significant Radiology Image Findings using Large-Scale Clinical Lesion Annotations

Extracting, harvesting and building large-scale annotated radiological image datasets is a greatly important yet challenging problem. It is also the bottleneck to designing more effective data-hungry computing paradigms (e.g., deep learning) for medical image analysis. Yet, vast amounts of clinical annotations (usually associated with disease image findings and marked using arrows, lines, lesion diameters, segmentation, etc.) have been collected over several decades and stored in hospitals' Picture Archiving and Communication Systems. In this paper, we mine and harvest one major type of clinical annotation data - lesion diameters annotated on bookmarked images - to learn an effective multi-class lesion detector via unsupervised and supervised deep Convolutional Neural Networks (CNN). Our dataset is composed of 33,688 bookmarked radiology images from 10,825 studies of 4,477 unique patients. For every bookmarked image, a bounding box is created to cover the target lesion based on its measured diameters. We categorize the collection of lesions using an unsupervised deep mining scheme to generate clustered pseudo lesion labels. Next, we adopt a regional-CNN method to detect lesions of multiple categories, regardless of missing annotations (normally only one lesion is annotated, despite the presence of multiple co-existing findings). Our integrated mining, categorization and detection framework is validated with promising empirical results, as a scalable, universal or multi-purpose CAD paradigm built upon abundant retrospective medical data. Furthermore, we demonstrate that detection accuracy can be significantly improved by incorporating pseudo lesion labels (e.g., Liver lesion/tumor, Lung nodule/tumor, Abdomen lesions, Chest lymph node and others). This dataset will be made publicly available (under the open science initiative).

cs.CV↗

Learning a Repression Network for Precise Vehicle Search

The growing explosion in the use of surveillance cameras in public security highlights the importance of vehicle search from large-scale image databases. Precise vehicle search, aiming at finding out all instances for a given query vehicle image, is a challenging task as different vehicles will look very similar to each other if they share same visual attributes. To address this problem, we propose the Repression Network (RepNet), a novel multi-task learning framework, to learn discriminative features for each vehicle image from both coarse-grained and detailed level simultaneously. Besides, benefited from the satisfactory accuracy of attribute classification, a bucket search method is proposed to reduce the retrieval time while still maintaining competitive performance. We conduct extensive experiments on the revised VehcileID dataset. Experimental results show that our RepNet achieves the state-of-the-art performance and the bucket search method can reduce the retrieval time by about 24 times.

cs.CV↗

Learning Domain-Invariant Subspace using Domain Features and Independence Maximization

Domain adaptation algorithms are useful when the distributions of the training and the test data are different. In this paper, we focus on the problem of instrumental variation and time-varying drift in the field of sensors and measurement, which can be viewed as discrete and continuous distributional change in the feature space. We propose maximum independence domain adaptation (MIDA) and semi-supervised MIDA (SMIDA) to address this problem. Domain features are first defined to describe the background information of a sample, such as the device label and acquisition time. Then, MIDA learns a subspace which has maximum independence with the domain features, so as to reduce the inter-domain discrepancy in distributions. A feature augmentation strategy is also designed to project samples according to their backgrounds so as to improve the adaptation. The proposed algorithms are flexible and fast. Their effectiveness is verified by experiments on synthetic datasets and four real-world ones on sensors, measurement, and computer vision. They can greatly enhance the practicability of sensor systems, as well as extend the application scope of existing domain adaptation algorithms by uniformly handling different kinds of distributional change.

cs.CV↗

Local Multiple Directional Pattern of Palmprint Image

Lines are the most essential and discriminative features of palmprint images, which motivate researches to propose various line direction based methods for palmprint recognition. Conventional methods usually capture the only one of the most dominant direction of palmprint images. However, a number of points in palmprint images have double or even more than two dominant directions because of a plenty of crossing lines of palmprint images. In this paper, we propose a local multiple directional pattern (LMDP) to effectively characterize the multiple direction features of palmprint images. LMDP can not only exactly denote the number and positions of dominant directions but also effectively reflect the confidence of each dominant direction. Then, a simple and effective coding scheme is designed to represent the LMDP and a block-wise LMDP descriptor is used as the feature space of palmprint images in palmprint recognition. Extensive experimental results demonstrate the superiority of the LMDP over the conventional powerful descriptors and the state-of-the-art direction based methods in palmprint recognition.

cs.CV↗