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Kei Nakamura

Publications and source records attributed to Kei Nakamura.

At least 19 recordsLinked to original sources

Energy-resolved measurement of individual GeV muon tracks generated by electrons from a compact Laser-Plasma Accelerator

Recently, the possibility of LPA-produced muon beams has gained significant interest within the accelerator application community. Directional, multi-GeV muons can be produced via Bethe-Heitler interactions when multi-GeV electrons hit solid targets. They are highly penetrating and, thanks to the compactness of the LPA, offer a path toward a deployable, active muon source. At the BELLA Center of the Lawrence Berkeley National Laboratory, we previously unambiguously detected muons generated during the interaction of multi-GeV electron beams with a 4 meter-thick electron beam dump. A new campaign has now extended our diagnostic capabilities to single-muon trajectory reconstruction and energy measurements. The setup allowed us to individually reconstruct each muon trajectory, defined by us as a muon passing through three detectors used for the reconstruction. For a subset of events, we extracted the muon energy from the magnetic-field bending angle, demonstrating production of GeV-scale muons. This work provides a key demonstration of track-based active-source muography, which enables non-invasive 3D density mapping of concealed or inaccessible samples, and it will accelerate the development of active LPA-based muon sources where compactness, controlled directionality, low divergence, and deep penetration are required.

physics.acc-ph

Radiation damage to normal mammalian tissue in vivo with laser-driven protons at ultra-high instantaneous dose rate

The differential sparing of normal tissues relative to tumor control observed at ultra-high dose rates, referred to as the FLASH effect, has recently gained considerable attention. The therapeutic advantages of FLASH radiotherapy are expected to be further amplified through the use of protons and ions, which enable precise dose deposition at tumor depth while minimizing irradiation of healthy tissues proximal and distal to the target. Nevertheless, the mechanism underlying this sparing effect remains poorly understood. Laser-driven proton accelerators are capable of delivering uniquely high instantaneous dose rates in ultrashort bunches. Here, we report the first in vivo investigation of normal tissue response to laser-driven proton irradiation, with controlled exposures to 8 MeV protons, delivering total doses up to 50 Gy at 2 Gy per laser shot. Our findings reveal a reduction in tissue swelling following laser-driven proton treatment compared with X-ray irradiations at conventional dose rates. RNA sequencing identified differential gene expression associated with immune and epidermal programs following laser-driven proton irradiations at two different dose levels.

physics.med-ph

Generation and control of Doppler harmonics approaching $10^{22}\textrm{W/cm}^2$ on plasma mirrors

In this letter, we report Doppler harmonic generation with a relativistic plasma mirror at unprecedented intensities $>10^{21} ~\textrm{W/cm}^2$ using a PetaWatt-class laser. We show that beyond a few $10^{21} ~\textrm{W/cm}^2$ a precise control of the laser contrast at the sub-picosecond time scale becomes essential to drive the efficient generation of high-order harmonics. Such control is paramount for deploying plasma mirrors in high-field applications at PetaWatt-class laser facilities, including, for instance, their use as intensity boosters in the pursuit of the strong-field regime of quantum electrodynamics.

physics.plasm-ph

Measurement of directional muon beams generated at the Berkeley Lab Laser Accelerator

We present the detection of directional muon beams produced using a PW laser at the Lawrence Berkeley National Laboratory. The muon source is a multi-GeV electron beam generated in a 30 cm laser plasma accelerator interacting with a high-Z converter target. The GeV photons resulting from the interaction are converted into a high-flux, directional muon beam via pair production. By employing scintillators to capture delayed events, we were able to identify the produced muons and characterize the source. Using theoretical knowledge of the muon production process combined with simulations that are in excellent agreement with the experiments, we demonstrate that the multi-GeV electron beams produce GeV-scale muons in numbers far exceeding those from cosmic background. Laser-plasma-accelerator-based muon sources can therefore enhance muon imaging applications thanks to their compactness, directionality, and high yields, which reduce the exposure time by orders of magnitude compared to cosmic ray muons. Using the Geant4-based simulation code we developed to gain insight into the experimental results, we can design future experiments and applications based on LPA-generated muons.

physics.acc-ph

Design Initiative for a 10 TeV pCM Wakefield Collider

This document outlines a community-driven Design Study for a 10 TeV pCM Wakefield Accelerator Collider. The 2020 ESPP Report emphasized the need for Advanced Accelerator R\&D, and the 2023 P5 Report calls for the ``delivery of an end-to-end design concept, including cost scales, with self-consistent parameters throughout." This Design Study leverages recent experimental and theoretical progress resulting from a global R\&D program in order to deliver a unified, 10 TeV Wakefield Collider concept. Wakefield Accelerators provide ultra-high accelerating gradients which enables an upgrade path that will extend the reach of Linear Colliders beyond the electroweak scale. Here, we describe the organization of the Design Study including timeline and deliverables, and we detail the requirements and challenges on the path to a 10 TeV Wakefield Collider.

physics.acc-ph

A Renewable Double Plasma Mirror For Petawatt-class Lasers

Exceptional pulse contrast can be critical for ultraintense laser experiments, particularly when using solid density targets, and their use is becoming widespread. However, current plasma mirror technology is becoming inadequate for the new generation of high repetition rate, high power lasers now available. We describe a novel double plasma mirror configuration based on renewable, free standing, ultrathin liquid crystal films tested at the BELLA Petawatt Laser Center. Although operating at a repetition rate of several shots per minute, this system can be scaled to a high repetition rate exceeding 1 Hz and represents an important step towards enabling sustained, continuous operation of plasma mirrors. We demonstrate an improvement of two to three orders of magnitude in contrast and a total throughput of 80%. We present the first measurements of a beam reflected from a single or double plasma mirror system using a wavefront sensor, showing a well preserved wavefront and spatial mode. Finally, we introduce a model that predicts the total throughput through this double plasma mirror. This is the first model that accurately predicts the peak reflectivity of a plasma mirror when given the laser temporal profile.

physics.plasm-ph

Dephasing of ion beams as Magnetic Vortex Acceleration regime transitions into a bubble-like field structure

The interaction of an ultra-intense laser pulse with a near critical density target results in the formation of a plasma channel, a strong azimuthal magnetic field and moving vortices. An application of this is the generation of energetic and collimated ion beams via Magnetic Vortex Acceleration. The optimized regime of Magnetic Vortex Acceleration is becoming experimentally accessible with new high intensity laser beamlines coming online and advances made in near critical density target fabrication. The robustness of the acceleration mechanism with realistic experimental conditions is examined with three-dimensional simulations. Of particular interest is the acceleration performance with different laser temporal contrast conditions, in some cases leading to pre-expanded target profiles prior to the arrival of the main pulse. Preplasma effects on the structure of the accelerating fields is explored, including a detailed analysis of the ion beam properties and the efficiency of the process. Improved scaling laws for the MVA mechanism, including the laser focal spot size effects, are presented.

physics.plasm-ph

Design Optimization of Permanent-Magnet Based Compact Transport Systems for Laser-Driven Proton Beams

Laser-driven (LD) ion acceleration has been explored in a newly constructed short focal length beamline at the BELLA petawatt facility (interaction point 2, iP2). For applications utilizing such LD ion beams, a beam transport system is required, which for reasons of compactness be ideally contained within 3 m. The large divergence and energy spread of LD ion beams present a unique challenge to transporting them compared to beams from conventional accelerators. This work gives an overview of proposed compact transport designs that can satisfy different requirements depending on the application for the iP2 proton beamline such as radiation biology, material science, and high energy density science. These designs are optimized for different parameters such as energy spread and peak proton density according to an application's need. The various designs consist solely of permanent magnet elements, which can provide high magnetic field gradients on a small footprint. While the field strengths are fixed, we have shown that the beam size and energy can be tuned effectively by varying the placement of the magnets. The performance of each design was evaluated based on high order particle tracking simulations of typical LD proton beams. A more detailed investigation was carried out for a design to deliver 10 MeV LD accelerated ions for radiation biology applications. With these transport system designs, the iP2 beamline is ready to house various application experiments.

physics.acc-ph

Online Charge Measurement for Petawatt Laser-Driven Ion Acceleration

Laser-driven ion beams have gained considerable attention for their potential use in multidisciplinary research and technology. Pre-clinical studies into their radiobiological effectiveness have established the prospect of using laser-driven ion beams for radiotherapy. In particular, research into the beneficial effects of ultra-high instantaneous dose rates is enabled by the high ion bunch charge and uniquely short bunch lengths present for laser-driven ion beams. Such studies require reliable, online dosimetry methods to monitor the bunch charge for every laser shot to ensure that the prescribed dose is accurately applied to the biological sample. In this paper we present the first successful use of an Integrating Current Transformer (ICT) for laser-driven ion accelerators. This is a non-invasive diagnostic to measure the charge of the accelerated ion bunch. It enables online dose measurements in radiobiological experiments and facilitates ion beam tuning, in particular, optimization of the laser ion source and alignment of the proton transport beamline. We present the ICT implementation and the correlation with other diagnostics such as radiochromic films, a Thomson parabola spectrometer and a scintillator.

physics.acc-ph

Defect engineering of silicon with ion pulses from laser acceleration

Defect engineering is foundational to classical electronic device development and for emerging quantum devices. Here, we report on defect engineering of silicon single crystals with ion pulses from a laser accelerator with ion flux levels up to 10^22 ions/cm^2/s. Low energy ions from plasma expansion of the laser-foil target are implanted near the surface and then diffuse into silicon samples that were locally pre-heated by high energy ions. We observe low energy ion fluences of ~10^16 cm^-2, about four orders of magnitude higher than the fluence of high energy (MeV) ions. In the areas of highest energy deposition, silicon crystals exfoliate from single ion pulses. Color centers, predominantly W and G-centers, form directly in response to ion pulses without a subsequent annealing step. We find that the linewidth of G-centers increase in areas with high ion flux much more than the linewidth of W-centers, consistent with density functional theory calculations of their electronic structure. Laser ion acceleration generates aligned pulses of high and low energy ions that expand the parameter range for defect engineering and doping of semiconductors with tunable balances of ion flux, damage rates and local heating.

cond-mat.mtrl-sci

Transformative Technology for FLASH Radiation Therapy: A Snowmass 2021 White Paper

Conventional cancer therapies include surgery, radiation therapy, chemotherapy, and, more recently, immunotherapy. These modalities are often combined to improve the therapeutic index. The general concept of radiation therapy is to increase the therapeutic index by creating a physical dose differential between tumors and normal tissues through precision dose targeting, image guidance, and high radiation beams that deliver radiation dose with high conformality, e.g., protons and ions. However, treatment and cure are still limited by normal tissue radiation toxicity, with many patients experiencing acute and long-term side effects. Recently, however, a fundamentally different paradigm for increasing the therapeutic index of radiation therapy has emerged, supported by preclinical research, and based on the FLASH radiation effect. FLASH radiation therapy (FLASH-RT) is an ultra-high dose-rate delivery of a therapeutic radiation dose within a fraction of a second. Experimental studies have shown that normal tissues seem to be universally spared at these high dose rates, whereas tumors are not. The dose delivery conditions are not yet fully characterized. Still, it is currently estimated that large doses of 10 Gy or more delivered in 200 ms or less produce normal tissue sparing effects yet effectively kill tumor cells. There is a great opportunity, but also many technical challenges, for the accelerator community to create the required dose rates with novel and compact accelerators to ensure the safe delivery of FLASH radiation beams.

physics.med-ph

A Survey of Spatio-Temporal Couplings throughout High-Power Ultrashort Lasers

The investigation of spatio-temporal couplings (STCs) of broadband light beams is becoming a key topic for the optimization as well as applications of ultrashort laser systems. This calls for accurate measurements of STCs. Yet, it is only recently that such complete spatio-temporal or spatio-spectral characterization has become possible, and it has so far mostly been implemented at the output of the laser systems, where experiments take place. In this survey, we present for the first time STC measurements at different stages of a collection of high-power ultrashort laser systems, all based on the chirped-pulse amplification (CPA) technique, but with very different output characteristics. This measurement campaign reveals spatio-temporal effects with various sources, and motivates the expanded use of STC characterization throughout CPA laser chains, as well as in a wider range of types of ultrafast laser systems. In this way knowledge will be gained not only about potential defects, but also about the fundamental dynamics and operating regimes of advanced ultrashort laser systems.

physics.optics

Spatio-temporal structure of a Petawatt femtosecond laser beam

The development of optical metrology suited to ultrafast lasers has played a key role in the progress of these light sources in the last few decades. Measurement techniques providing the complete $E$-field of ultrashort laser beams in both time and space are now being developed. Yet, they had so far not been applied to the most powerful ultrashort lasers, which reach the PetaWatt range by pushing the Chirped Pulse Amplification scheme to its present technical limits. This situation left doubts on their actual performance, and in particular on the peak intensity they can reach at focus. In this article we present the first complete spatio-temporal characterization of a PetaWatt femtosecond laser operating at full intensity, the BELLA laser, using two recently-developed independent measurement techniques. Our results demonstrate that, with adequate optimization, the CPA technique is still suitable at these extreme scales, i.e., it is not inherently limited by spatio-temporal couplings. We also show how these measurements provide unprecedented insight into the physics and operation regime of such laser systems.

physics.optics

The complexity of prime 3-manifolds and the first $\mathbb{Z}_{/2\mathbb{Z}}$-cohomology of small rank

For a closed orientable connected 3-manifold $M$, its complexity $\boldsymbol{T}(M)$ is defined to be the minimal number of tetrahedra in its triangulations. Under the assumption that $M$ is prime (but not necessarily atoroidal), we establish a lower bound for the complexity $\boldsymbol{T}(M)$ in terms of the $\mathbb{Z}_{/2\mathbb{Z}}$-coefficient Thurston norm for $H^1(M;\mathbb{Z}_{/2\mathbb{Z}})$: (1) for any rank-1 subgroup $\{0,φ\} \leqslant H^1(M;\mathbb{Z}_{/2\mathbb{Z}})$, we have $\boldsymbol{T}(M) \geqslant 2+2||φ||$ unless $M$ is a lens space with $\boldsymbol{T}(M)=1+2||φ||$; (2) for any rank-2 subgroup $\{0,φ_1,φ_2,φ_3\} \leqslant H^1(M;\mathbb{Z}_{/2\mathbb{Z}})$, we have $\boldsymbol{T}(M) \geqslant 2+||φ_1||+||φ_2||+||φ_3||$. Under the extra assumption that $M$ is atoroidal, these inequalities had already been shown by Jaco, Rubinstein, and Tillmann. Our work here shows that we do not need to require $M$ to be atoroidal.

math.GT

Geometry and Arithmetic of Crystallographic Sphere Packings

We introduce the notion of a "crystallographic sphere packing," defined to be one whose limit set is that of a geometrically finite hyperbolic reflection group in one higher dimension. We exhibit for the first time an infinite family of conformally-inequivalent such with all radii being reciprocals of integers. We then prove a result in the opposite direction: the "superintegral" ones exist only in finitely many "commensurability classes," all in dimensions below 30.

math.MG

The local-global principle for integral bends in orthoplicial Apollonian sphere packings

We introduce an orthoplicial Apollonian sphere packing, which is a sphere packing obtained by successively inverting a configuration of 8 spheres with 4-orthplicial tangency graph. We will show that there are such packings in which the bends of all constituent spheres are integral, and establish the asymptotic local-global principle for the set of bends in these packings.

math.NT

On Isosystolic Inequalities for T^n, RP^n, and M^3

If a closed smooth n-manifold M admits a finite cover whose Z/2Z-cohomology has the maximal cup-length, then for any riemannian metric g on M, we show that the systole Sys(M,g) and the volume Vol(M,g) of the riemannian manifold (M,g) are related by the following isosystolic inequality: Sys(M,g)^n \leq n! Vol(M,g). The inequality can be regarded as a generalization of Burago and Hebda's inequality for closed essential surfaces and as a refinement of Guth's inequality for closed n-manifolds whose Z/2Z-cohomology has the maximal cup-length. We also establish the same inequality in the context of possibly non-compact manifolds under a similar cohomological condition. The inequality applies to (i) T^n and all other compact euclidean space forms, (ii) RP^n and many other spherical space forms including the Poincaré dodecahedral space, and (iii) most closed essential 3-manifolds including all closed aspherical 3-manifolds.

math.DG

Fox reimbedding and Bing submanifolds

Let M be an orientable closed connected 3-manifold. We introduce the notion of amalgamated Heegaard genus of M with respect to a closed separating 2-manifold F, and use it to show that the following two statements are equivalent: (i) a compact connected 3-manifold Y can be embedded in M so that the exterior of the image of Y is a union of handlebodies; and (ii) a compact connected 3-manifold Y can be embedded in M so that every knot in M can be isotoped to lie within the image of Y . Our result can be regarded as a common generalization of the reimbedding theorem by Fox [Fox48] and the characterization of 3-sphere by Bing [Bin58], as well as more recent results of Hass and Thompson [HT89] and Kobayashi and Nishi [KN94].

math.GT