SearcharxivSearch

arXiv subjects

Kelly Bodwin

Publications and source records attributed to Kelly Bodwin.

2 recordsLinked to original sources

Latent Association Mining in Binary Data

We consider the problem of identifying stable sets of mutually associated features in moderate or high-dimensional binary data. In this context we develop and investigate a method called Latent Association Mining for Binary Data (LAMB). The LAMB method is based on a simple threshold model in which the observed binary values represent a random thresholding of a latent continuous vector that may have a complex association structure. We consider a measure of latent association that quantifies association in the latent continuous vector without bias due to the random thresholding. The LAMB method uses an iterative testing based search procedure to identify stable sets of mutually associated features. We compare the LAMB method with several competing methods on artificial binary-valued datasets and two real count-valued datasets. The LAMB method detects meaningful associations in these datasets. In the case of the count-valued datasets, associations detected by the LAMB method are based only on information about whether the counts are zero or non-zero, and is competitive with methods that have access to the full count data.

stat.ME

A testing-based approach to the discovery of differentially correlated variable sets

Given data obtained under two sampling conditions, it is often of interest to identify variables that behave differently in one condition than in the other. We introduce a method for differential analysis of second-order behavior called Differential Correlation Mining (DCM). The DCM method identifies differentially correlated sets of variables, with the property that the average pairwise correlation between variables in a set is higher under one sample condition than the other. DCM is based on an iterative search procedure that adaptively updates the size and elements of a candidate variable set. Updates are performed via hypothesis testing of individual variables, based on the asymptotic distribution of their average differential correlation. We investigate the performance of DCM by applying it to simulated data as well as recent experimental datasets in genomics and brain imaging.

stat.ME