Comparative Performance and Parameter-Efficient Adaptation of DINOv2 for Active Trachoma Classification
Automated grading of conjunctival photographs could reduce the cost and variability of trachoma prevalence surveys, but the relative value of modern pretrained visual representations, lightweight feature adaptation, and training-objective design has not been established under a common protocol. This study presents a controlled evaluation for binary classification of Trachomatous Inflammation-Follicular (TF) versus Normal using 1,546 images from the public UCSF/Lietman collection. Images are processed using the OPTED pipeline for zero-shot tarsal-conjunctiva segmentation, alignment, cropping, and standardization. We first compare six pretrained backbones using a common classification pipeline and then evaluate four lightweight adaptation mechanisms on DINOv2 ViT-B/14. Under stratified five-fold cross-validation, DINOv2 with Efficient Channel Attention (ECA) and focal-plus-center loss achieved 91.66 +/- 0.97% accuracy, 90.69 +/- 1.10% macro-F1, and 96.06 +/- 0.71% AUC. ECA introduces only five learnable parameters while matching the performance of substantially larger alternatives. Objective ablation further showed that ECA did not consistently improve plain DINOv2 across loss functions; the lowest-variance 91.66% accuracy was obtained with cross-entropy plus center loss. Overall, the fine-tuned DINOv2 representation provided most of the predictive performance, while ECA offered a highly parameter-efficient refinement whose effect depended on the training objective. The resulting workflow provides a reproducible benchmark for active trachoma image classification.