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Konstantin Popov

Publications and source records attributed to Konstantin Popov.

8 recordsLinked to original sources

Staging by the Book: Automatic Sleep Stage Classification Using Scoring Rules

Automated sleep staging is commonly approached as a supervised machine learning problem, with deep learning methods dominating recent research. While machine learning models achieve near-human level agreement with human-scored reference sleep stages, their decisions are typically opaque and not designed to follow clinical scoring rules. We propose a transparent alternative: a deterministic, rule-based sleep staging method that explicitly operationalizes the American Academy of Sleep Medicine's (AASM) scoring logic as executable code, coupled with epoch-level natural-language justifications derived from an explanation trace. We evaluate the approach on 50 polysomnography recordings with a 10-scorer majority-vote consensus as reference. Across all recordings, the method agreed with the majority-vote reference in 60.5% of epochs ($κ=0.42$), with substantially higher agreement on a dataset used during development (77.1%, $κ=0.61$). Agreement with the reference was highest for sleep stage N2 (recall 83.5%) and moderate for sleep stage R (recall 68.7%), while Wake and N1 recall were low. Despite lower agreement with the reference than contemporary deep learning models, the method provides deterministic decisions and natural language explanations aligned with AASM scoring rules, making it a complementary tool for auditing, debugging, and governing deep learning-based sleep staging.

eess.SP

All-atomistic Transferable Neural Potentials for Protein Solvation

Implicit solvent models are widely used to decrease the number of solvent degrees of freedom and enable the calculation of solvation energetics without water molecules. However, its accuracy often falls short compared to explicit models. Recent advancements in neural potentials have shown promise in drug discovery, but transferability remains a persistent challenge. Here, we introduce the Protein Hydration Neural Network (PHNN), an implicit solvent model that extends analytical continuum solvation by learning transferable corrections to model parameters instead of applying post hoc adjustments to final energies. The model is explicitly designed to maximize data efficiency by leveraging physical priors embedded in the data. We demonstrate that PHNN improves accuracy relative to traditional analytical methods and maintains predictive accuracy on out-of-domain protein systems.

physics.chem-ph

KEK Accelerator Test Facility Low-Level RF and Timing Systems

The KEK Accelerator Test Facility (ATF) is a dedicated testbed for nanobeam technologies in support of the International Linear Collider (ILC). Stable pulsed operation requires synchronization of the facility timing system with the Low-Level RF (LLRF) system. The timing system distributes trigger and gate signals to key subsystems, including the DAQ, klystrons, laser systems, pulsed kicker magnets, and interlocks. The LLRF system provides phase-coherent RF references and facility-wide clock distribution for synchronization. Achieving ~100 fs-level synchronization depends critically on the phase-noise power spectral density (PN-PSD) of the distributed clock signals and on preserving this performance throughout the distribution network. We present facility-wide measurements of the KEK ATF LLRF clock PN-PSD and discuss the resulting synchronization floor imposed by the stability of the ATF Linac and Damping Ring signal generators.

physics.acc-ph

Study of laser-beam arrival time synchronization towards sub-picosecond stability level

A precise synchronization between laser pulse and electron beam arrival time is essential for achieving sub-picosecond stability in modern accelerator facilities. In this work, a Low-Level RF system architecture combined with White Rabbit based timing system has been tested through a collaboration between KEK (Japan) and CNRS/IN2P3, IJClab (France). The setup combines a frequency standard generator, an IDROGEN carrier board with an embedded White Rabbit node, and SkyWorks synthesizers of different form factors to distribute phase-locked clock signals over telecommunication fiber. Phase noise power spectral density measurements were performed at several RF sub-harmonics to confirm synchronization performance. These results demonstrate the feasibility of implementing the White Rabbit-IDROGEN synchronization scheme for large-scale accelerators, including applications to laser-based diagnostics.

physics.acc-ph

Measurement of Position Resolutions of L-band Cavity Beam Position Monitors

Beam position monitors (BPMs) are indispensable components of modern particle accelerators, providing real-time diagnostics to ensure precise beam control, stability, and quality. As accelerators such as the International Linear Collider (ILC) aim for nanometer-scale beam sizes at the interaction point, stringent requirements on position resolution arise. Specifically, the main linac of the ILC demands a BPM resolution better than 5 μm to support stable beam transport and minimize emittance growth. To address this, we have developed an L-band cavity BPM optimized for the beam conditions of the ILC. In this paper, we introduce a prototype of an L-band cavity BPM and its signal processing system, describe the methodology for position resolution measurements, discuss the problems and solutions encountered in the past experiment, and report the projected position resolutions of about 300 nm at best.

physics.acc-ph

Self-Employment as a Signal: Career Concerns with Hidden Firm Performance

We study a stationary labour market in which risk-averse workers privately know their permanent talent and choose between risky self-employment, which produces portable public outcomes, and firm employment, which pays a competitive wage but keeps individual performance hidden. Because workers decide whether to generate another public outcome or apply to a firm, both public records and applicant pools are endogenous. We construct market beliefs from the stationary flow of types through all histories leading to each record and then condition them on the current application decision. If the effective continuation factor is below one half, a stationary sequential competitive equilibrium exists and occupational choice follows a talent cutoff at every record. Firm employment is persistent whenever it is strictly optimal for a given worker type at a given record. At any on-path record where both occupations are chosen, higher-talent workers select into self-employment, while the applicant wage lies below mean talent among workers holding that record. This wage discount decomposes exactly into the self-employed share and the talent gap between self-employed workers and applicants. The model yields within-record predictions for occupational choice, wages, subsequent performance, and the duration of opaque employment spells.

econ.TH

Imaging the noncentrosymmetric structural organisation of tissue with Interferometric Second Harmonic Generation microscopy

We report the imaging of tendon, a connective tissue rich in collagen type I proteins, with Interferometric Second Harmonic Generation (I-SHG) microscopy. We observed that the noncentrosymmetric structural organization can be maintained along the fibrillar axis over more than 150 μm, while in the transverse direction it is ~1-15 μm. Those results are explained by modeling tendon as a heterogeneous distribution of noncentrosymmetric nanocylinders (collagen fibrils) oriented along the fibrillar axis. The preservation of the noncentrosymmetric structural organization over multiple tens of microns reveals that tendon is made of domains in which the fraction occupied by fibrils oriented in one direction is larger than in the other.

physics.bio-ph

The Theory of Fermi Condensate Quantum Phase Transition

This report is devoted to the building of the theory and analyzing the phenomenon which take place in such strong correlated Fermi systems as High temperature superconductors, metals with heavy fermions and quasi two dimensional Fermi-systems. The described theory of strong correlated Fermi systems bases on conceptions of Fermi condensate quantum phase transition (FCQPT) and Fermi condensate. It develops the well known Landau paradigm based on quasi particles formalism and order parameter. The description of the FCQPT theory is followed by its verification on the different exactly solvable models, by numerical calculations and by comparing with wide collection of experimental data.

cond-mat.str-el