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Kristian A. Stevens

Publications and source records attributed to Kristian A. Stevens.

2 recordsLinked to original sources

Stochasticity Is Not the Hard Part: Reduction and Complexity in Instructional Sequencing over Prerequisite DAGs

When a student must learn concepts connected by prerequisite dependencies, when does the order of instruction matter, and what does it cost to find the best one? We study instructional sequencing as a stochastic shortest-path problem in which attempting a concept succeeds with a state-dependent probability and failure leaves the learner state unchanged. We first prove that this stochasticity can be eliminated exactly: the problem collapses to a deterministic shortest-path problem on the lattice of prerequisite order ideals, preserving optimal values and actions. The collapse removes stochastic complexity but not combinatorial complexity: optimal sequencing remains NP-hard -- via reduction from feedback arc set in tournaments -- even with no prerequisite edges, unit costs, uniform binary nonnegative transfer, and success probabilities at least $1/2$. Hardness is not uniform: when realizable transfer preferences remain jointly acyclic with the prerequisites, any topological order of the residual joint graph is optimal, and fixed prerequisite width yields polynomial-time exact dynamic programming. A computable diagnostic, $mĪ”$, bounds the value of sequencing before optimization. On 70,893 interactions from an introductory CS course, the diagnostic certifies a doubly easy regime -- little value to optimize and little space to search -- while constructed transfer instances realize the challenging regime, where myopic sequencing suffers large regret yet exact A* with a consistent heuristic expands only linearly many states on that family.

cs.AI↗

Population genomics of sub-Saharan Drosophila melanogaster: African diversity and non-African admixture

(ABRIDGED) We report the genome sequencing of 139 wild-derived strains of D. melanogaster, representing 22 population samples from the sub-Saharan ancestral range of this species, along with one European population. Most genomes were sequenced above 25X depth from haploid embryos. Results indicated a pervasive influence of non-African admixture in many African populations, motivating the development and application of a novel admixture detection method. Admixture proportions varied among populations, with greater admixture in urban locations. Admixture levels also varied across the genome, with localized peaks and valleys suggestive of a non-neutral introgression process. Genomes from the same location differed starkly in ancestry, suggesting that isolation mechanisms may exist within African populations. After removing putatively admixed genomic segments, the greatest genetic diversity was observed in southern Africa (e.g. Zambia), while diversity in other populations was largely consistent with a geographic expansion from this potentially ancestral region. The European population showed different levels of diversity reduction on each chromosome arm, and some African populations displayed chromosome arm-specific diversity reductions. Inversions in the European sample were associated with strong elevations in diversity across chromosome arms. Genomic scans were conducted to identify loci that may represent targets of positive selection. A disproportionate number of candidate selective sweep regions were located near genes with varied roles in gene regulation. Outliers for Europe-Africa FST were found to be enriched in genomic regions of locally elevated cosmopolitan admixture, possibly reflecting a role for some of these loci in driving the introgression of non-African alleles into African populations.

q-bio.PE↗