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Kui Wang

Publications and source records attributed to Kui Wang.

58 records · Page 4Linked to original sources

Isoperimetric comparisons via viscosity

Viscosity solutions are suitable notions in the study of nonlinear PDEs justified by estimates established via the maximum principle or the comparison principle. Here we prove that the isoperimetric profile functions of Riemannian manifolds with Ricci lower bound are viscosity super-solutions of some nonlinear differential equations. From these one can derive the isoperimetric inequalities of Lévy-Gromov and Bérard-Besson-Gallot, as well as some new comparison results.

math.DG↗

Singularities of mean curvature flow and isoperimetric inequalities in H^3

In this article, by following the method in \cite{PT}, combining Willmore energy with isoperimetric inequalities, we construct two examples of singularities under mean curvature flow in $\mathbb{H}^3$. More precisely, there exists a torus, which must develop a singularity under MCF before the volume it encloses decreases to zero. There also exists a topological sphere in the shape of a dumbbell, which must develop a singularity in the flow before its area shrinks to zero. Simultaneously, by using the flow, we proved an isoperimetric inequality for some domains in $\mathbb{H}^3$.

math.DG↗

Joint Modeling and Registration of Cell Populations in Cohorts of High-Dimensional Flow Cytometric Data

In systems biomedicine, an experimenter encounters different potential sources of variation in data such as individual samples, multiple experimental conditions, and multi-variable network-level responses. In multiparametric cytometry, which is often used for analyzing patient samples, such issues are critical. While computational methods can identify cell populations in individual samples, without the ability to automatically match them across samples, it is difficult to compare and characterize the populations in typical experiments, such as those responding to various stimulations or distinctive of particular patients or time-points, especially when there are many samples. Joint Clustering and Matching (JCM) is a multi-level framework for simultaneous modeling and registration of populations across a cohort. JCM models every population with a robust multivariate probability distribution. Simultaneously, JCM fits a random-effects model to construct an overall batch template -- used for registering populations across samples, and classifying new samples. By tackling systems-level variation, JCM supports practical biomedical applications involving large cohorts.

stat.ML↗