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Kunihiko Sadakane

Publications and source records attributed to Kunihiko Sadakane.

26 records · Page 2Linked to original sources

Packed Compact Tries: A Fast and Efficient Data Structure for Online String Processing

In this paper, we present a new data structure called the packed compact trie (packed c-trie) which stores a set $S$ of $k$ strings of total length $n$ in $n \logσ+ O(k \log n)$ bits of space and supports fast pattern matching queries and updates, where $σ$ is the size of an alphabet. Assume that $α= \log_σn$ letters are packed in a single machine word on the standard word RAM model, and let $f(k,n)$ denote the query and update times of the dynamic predecessor/successor data structure of our choice which stores $k$ integers from universe $[1,n]$ in $O(k \log n)$ bits of space. Then, given a string of length $m$, our packed c-tries support pattern matching queries and insert/delete operations in $O(\frac{m}α f(k,n))$ worst-case time and in $O(\frac{m}α + f(k,n))$ expected time. Our experiments show that our packed c-tries are faster than the standard compact tries (a.k.a. Patricia trees) on real data sets. As an application of our packed c-trie, we show that the sparse suffix tree for a string of length $n$ over prefix codes with $k$ sampled positions, such as evenly-spaced and word delimited sparse suffix trees, can be constructed online in $O((\frac{n}α + k) f(k,n))$ worst-case time and $O(\frac{n}α + k f(k,n))$ expected time with $n \log σ+ O(k \log n)$ bits of space. When $k = O(\frac{n}α)$, by using the state-of-the-art dynamic predecessor/successor data structures, we obtain sub-linear time construction algorithms using only $O(\frac{n}α)$ bits of space in both cases. We also discuss an application of our packed c-tries to online LZD factorization.

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MEGAHIT: An ultra-fast single-node solution for large and complex metagenomics assembly via succinct de Bruijn graph

MEGAHIT is a NGS de novo assembler for assembling large and complex metagenomics data in a time- and cost-efficient manner. It finished assembling a soil metagenomics dataset with 252Gbps in 44.1 hours and 99.6 hours on a single computing node with and without a GPU, respectively. MEGAHIT assembles the data as a whole, i.e., it avoids pre-processing like partitioning and normalization, which might compromise on result integrity. MEGAHIT generates 3 times larger assembly, with longer contig N50 and average contig length than the previous assembly. 55.8% of the reads were aligned to the assembly, which is 4 times higher than the previous. The source code of MEGAHIT is freely available at https://github.com/voutcn/megahit under GPLv3 license.

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Variable-Order de Bruijn Graphs

The de Bruijn graph $G_K$ of a set of strings $S$ is a key data structure in genome assembly that represents overlaps between all the $K$-length substrings of $S$. Construction and navigation of the graph is a space and time bottleneck in practice and the main hurdle for assembling large, eukaryote genomes. This problem is compounded by the fact that state-of-the-art assemblers do not build the de Bruijn graph for a single order (value of $K$) but for multiple values of $K$. More precisely, they build $d$ de Bruijn graphs, each with a specific order, i.e., $G_{K_1}, G_{K_2}, ..., G_{K_d}$. Although, this paradigm increases the quality of the assembly produced, it increases the memory by a factor of $d$ in most cases. In this paper, we show how to augment a succinct de Bruijn graph representation by Bowe et al. (Proc. WABI, 2012) to support new operations that let us change order on the fly, effectively representing all de Bruijn graphs of order up to some maximum $K$ in a single data structure. Our experiments show our variable-order de Bruijn graph only modestly increases space usage, construction time, and navigation time compared to a single order graph.

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Random Access to Grammar Compressed Strings

Grammar based compression, where one replaces a long string by a small context-free grammar that generates the string, is a simple and powerful paradigm that captures many popular compression schemes. In this paper, we present a novel grammar representation that allows efficient random access to any character or substring without decompressing the string. Let $S$ be a string of length $N$ compressed into a context-free grammar $\mathcal{S}$ of size $n$. We present two representations of $\mathcal{S}$ achieving $O(\log N)$ random access time, and either $O(n\cdot α_k(n))$ construction time and space on the pointer machine model, or $O(n)$ construction time and space on the RAM. Here, $α_k(n)$ is the inverse of the $k^{th}$ row of Ackermann's function. Our representations also efficiently support decompression of any substring in $S$: we can decompress any substring of length $m$ in the same complexity as a single random access query and additional $O(m)$ time. Combining these results with fast algorithms for uncompressed approximate string matching leads to several efficient algorithms for approximate string matching on grammar-compressed strings without decompression. For instance, we can find all approximate occurrences of a pattern $P$ with at most $k$ errors in time $O(n(\min\{|P|k, k^4 + |P|\} + \log N) + occ)$, where $occ$ is the number of occurrences of $P$ in $S$. Finally, we generalize our results to navigation and other operations on grammar-compressed ordered trees. All of the above bounds significantly improve the currently best known results. To achieve these bounds, we introduce several new techniques and data structures of independent interest, including a predecessor data structure, two "biased" weighted ancestor data structures, and a compact representation of heavy paths in grammars.

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Detecting Superbubbles in Assembly Graphs

We introduce a new concept of a subgraph class called a superbubble for analyzing assembly graphs, and propose an efficient algorithm for detecting it. Most assembly algorithms utilize assembly graphs like the de Bruijn graph or the overlap graph constructed from reads. From these graphs, many assembly algorithms first detect simple local graph structures (motifs), such as tips and bubbles, mainly to find sequencing errors. These motifs are easy to detect, but they are sometimes too simple to deal with more complex errors. The superbubble is an extension of the bubble, which is also important for analyzing assembly graphs. Though superbubbles are much more complex than ordinary bubbles, we show that they can be efficiently enumerated. We propose an average-case linear time algorithm (i.e., O(n+m) for a graph with n vertices and m edges) for graphs with a reasonable model, though the worst-case time complexity of our algorithm is quadratic (i.e., O(n(n+m))). Moreover, the algorithm is practically very fast: Our experiments show that our algorithm runs in reasonable time with a single CPU core even against a very large graph of a whole human genome.

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CRAM: Compressed Random Access Memory

We present a new data structure called the \emph{Compressed Random Access Memory} (CRAM) that can store a dynamic string $T$ of characters, e.g., representing the memory of a computer, in compressed form while achieving asymptotically almost-optimal bounds (in terms of empirical entropy) on the compression ratio. It allows short substrings of $T$ to be decompressed and retrieved efficiently and, significantly, characters at arbitrary positions of $T$ to be modified quickly during execution \emph{without decompressing the entire string}. This can be regarded as a new type of data compression that can update a compressed file directly. Moreover, at the cost of slightly increasing the time spent per operation, the CRAM can be extended to also support insertions and deletions. Our key observation that the empirical entropy of a string does not change much after a small change to the string, as well as our simple yet efficient method for maintaining an array of variable-length blocks under length modifications, may be useful for many other applications as well.

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Fully-Functional Static and Dynamic Succinct Trees

We propose new succinct representations of ordinal trees, which have been studied extensively. It is known that any $n$-node static tree can be represented in $2n + o(n)$ bits and a number of operations on the tree can be supported in constant time under the word-RAM model. However the data structures are complicated and difficult to dynamize. We propose a simple and flexible data structure, called the range min-max tree, that reduces the large number of relevant tree operations considered in the literature to a few primitives that are carried out in constant time on sufficiently small trees. The result is extended to trees of arbitrary size, achieving $2n + O(n /\polylog(n))$ bits of space. The redundancy is significantly lower than any previous proposal. Our data structure builds on the range min-max tree to achieve $2n+O(n/\log n)$ bits of space and $O(\log n)$ time for all the operations. We also propose an improved data structure using $2n+O(n\log\log n/\log n)$ bits and improving the time to the optimal $O(\log n/\log \log n)$ for most operations. Furthermore, we support sophisticated operations that allow attaching and detaching whole subtrees, in time $\Order(\log^{1+ε} n / \log\log n)$. Our techniques are of independent interest. One allows representing dynamic bitmaps and sequences supporting rank/select and indels, within zero-order entropy bounds and optimal time $O(\log n / \log\log n)$ for all operations on bitmaps and polylog-sized alphabets, and $O(\log n \log σ/ (\log\log n)^2)$ on larger alphabet sizes $σ$. This improves upon the best existing bounds for entropy-bounded storage of dynamic sequences, compressed full-text self-indexes, and compressed-space construction of the Burrows-Wheeler transform.

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Practical Entropy-Compressed Rank/Select Dictionary

Rank/Select dictionaries are data structures for an ordered set $S \subset \{0,1,...,n-1\}$ to compute $\rank(x,S)$ (the number of elements in $S$ which are no greater than $x$), and $\select(i,S)$ (the $i$-th smallest element in $S$), which are the fundamental components of \emph{succinct data structures} of strings, trees, graphs, etc. In those data structures, however, only asymptotic behavior has been considered and their performance for real data is not satisfactory. In this paper, we propose novel four Rank/Select dictionaries, esp, recrank, vcode and sdarray, each of which is small if the number of elements in $S$ is small, and indeed close to $nH_0(S)$ ($H_0(S) \leq 1$ is the zero-th order \textit{empirical entropy} of $S$) in practice, and its query time is superior to the previous ones. Experimental results reveal the characteristics of our data structures and also show that these data structures are superior to existing implementations in both size and query time.

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