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Kwaku Forkuoh Darkwah

Publications and source records attributed to Kwaku Forkuoh Darkwah.

2 recordsLinked to original sources

Fractional Optimal Control Model of SARS-CoV-2 (COVID-19) Disease in Ghana

Research focus on optimal control problems brought on by fractional differential equations has been extensively applied in practice. However, because they are still open-ended and challenging, a number of problems with fractional mathematical modeling and problems with optimal control require additional study. Using fractional-order derivatives defined in the Atangana Baleanu Caputo sense, we alter the integer-order model that has been proposed in the literature. We prove the solution's existence, uniqueness, equilibrium points, fundamental reproduction number, and local stability of the equilibrium points. The operator's numerical approach was put into practice to obtain a numerical simulation to back up the analytical conclusions. Fractional optimum controls were incorporated into the model to identify the most efficient intervention strategies for controlling the disease. Utilizing actual data from Ghana for the months of March 2020 to March 2021, the model is validated. The simulation's results show that the fractional operator significantly affected each compartment and that the incidence rate of the population rose when v>0.6. The examination of the most effective control technique discovered that social exclusion and vaccination were both very effective methods for halting the development of the illness.

q-bio.PE↗

An Optimal Control Model of transmission dynamics of COVID-19 in Ghana

Almost every country in the world is battling to limit the spread of COVID-19. As the world strives to get an effective medication to control the disease, appropriate intervention measures, for now, remains one of the effective methods to reduce the spread of the disease. Optimal control strategies have proven to be an effective method in curtailing the spread of infectious diseases. In this paper, a model has been formulated to study transmission dynamics of the disease. Basic properties of the model such as the basic reproduction number, equilibrium points and stability of the equilibrium points have been determined. Sensitivity analysis was carried on to determine the impact of the model parameters on the basic reproduction number. We also introduced a compartment for the deceased and examined the behaviour of COVID-19 related deaths. The numerical simulation prediction is consistent with real data from Ghana for the period March 2020 to March 2021. The simulation revealed the disease had less impact on the population during the first seven months of the outbreak. To help contain the spread of the disease, time dependent optimal controls were incorporated into the model and Pontryagin maximum principle was used to characterize vital conditions of the optimal control model. Numerical simulations of the optimal control model showed that, combination of optimal preventive strategies such as nose mask and vaccination are effective to significantly decrease the number of COVID-19 cases in different compartments of the model. Vaccination decreases the susceptibility to the disease whereas mask usage preserved the susceptible population from extinction.

q-bio.PE↗