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L. Bortolussi

Publications and source records attributed to L. Bortolussi.

3 recordsLinked to original sources

Deep artificial neural network for prediction of atrial fibrillation through the analysis of 12-leads standard ECG

Atrial Fibrillation (AF) is a heart's arrhythmia which, despite being often asymptomatic, represents an important risk factor for stroke, therefore being able to predict AF at the electrocardiogram exam, would be of great impact on actively targeting patients at high risk. In the present work we use Convolution Neural Networks to analyze ECG and predict Atrial Fibrillation starting from realistic datasets, i.e. considering fewer ECG than other studies and extending the maximal distance between ECG and AF diagnosis. We achieved 75.5% (0.75) AUC firstly increasing our dataset size by a shifting technique and secondarily using the dilation parameter of the convolution neural network. In addition we find that, contrarily to what is commonly used by clinicians reporting AF at the exam, the most informative leads for the task of predicting AF are D1 and avR. Similarly, we find that the most important frequencies to check are in the range of 5-20 Hz. Finally, we develop a net able to manage at the same time the electrocardiographic signal together with the electronic health record, showing that integration between different sources of data is a profitable path. In fact, the 2.8% gain of such net brings us to a 78.6% (std 0.77) AUC. In future works we will deepen both the integration of sources and the reason why we claim avR is the most informative lead.

eess.SP

A Logic for Monitoring Dynamic Networks of Spatially-distributed Cyber-Physical Systems

Cyber-Physical Systems (CPS) consist of inter-wined computational (cyber) and physical components interacting through sensors and/or actuators. Computational elements are networked at every scale and can communicate with each other and with humans. Nodes can join and leave the network at any time or they can move to different spatial locations. In this scenario, monitoring spatial and temporal properties plays a key role in the understanding of how complex behaviors can emerge from local and dynamic interactions. We revisit here the Spatio-Temporal Reach and Escape Logic (STREL), a logic-based formal language designed to express and monitor spatio-temporal requirements over the execution of mobile and spatially distributed CPS. STREL considers the physical space in which CPS entities (nodes of the graph) are arranged as a weighted graph representing their dynamic topological configuration. Both nodes and edges include attributes modeling physical and logical quantities that can evolve over time. STREL combines the Signal Temporal Logic with two spatial modalities reach and escape that operate over the weighted graph. From these basic operators, we can derive other important spatial modalities such as everywhere, somewhere and surround. We propose both qualitative and quantitative semantics based on constraint semiring algebraic structure. We provide an offline monitoring algorithm for STREL and we show the feasibility of our approach with the application to two case studies: monitoring spatio-temporal requirements over a simulated mobile ad-hoc sensor network and a simulated epidemic spreading model for COVID19.

cs.LO

Qualitative and Quantitative Monitoring of Spatio-Temporal Properties with SSTL

In spatially located, large scale systems, time and space dynamics interact and drives the behaviour. Examples of such systems can be found in many smart city applications and Cyber-Physical Systems. In this paper we present the Signal Spatio-Temporal Logic (SSTL), a modal logic that can be used to specify spatio-temporal properties of linear time and discrete space models. The logic is equipped with a Boolean and a quantitative semantics for which efficient monitoring algorithms have been developed. As such, it is suitable for real-time verification of both white box and black box complex systems. These algorithms can also be combined with stochastic model checking routines. SSTL combines the until temporal modality with two spatial modalities, one expressing that something is true somewhere nearby and the other capturing the notion of being surrounded by a region that satisfies a given spatio-temporal property. The monitoring algorithms are implemented in an open source Java tool. We illustrate the use of SSTL analysing the formation of patterns in a Turing Reaction-Diffusion system and spatio-temporal aspects of a large bike-sharing system.

cs.LO